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Clonus

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thigh horizontal and foot supported on the floor. Move the foot inward toward you so that the heel is off the floor and the ball of the foot supports the weight of the leg. When the weights and angles are correctly adjusted, an oscillation will start in the muscle of the calf with a frequency of about six to eight per second and an amplitude of about half an inch at the knee. This oscillation is called
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Balance is a partly involuntary and unconscious business, dependent on "spinal reflexes." When provided with appropriate context, these reflexes go into oscillation that is called "clonus," a phenomenon that is familiar to everybody and which is easily produced. (While sitting, place the leg with
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likely due to their common physiological origins. Some consider clonus as simply an extended outcome of spasticity. Although closely linked, clonus is not seen in all patients with spasticity. Clonus tends to not be present with spasticity in patients with significantly increased
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injury). This lack of inhibition biases neurons to a net excitatory state, therefore increasing total signal conduction. Signaling delay is present due to an increased nerve conduction time. Long delays are primarily due to long reflex pathways, which are common in
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The self re-excitation of hyperactive stretch reflexes theory involves a repetitive contract-relax cycle in the affected muscle, which creates oscillatory movements in the affected limb. In order for self re-excitation to exist, both an increase in
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in neurophysiology and is a recurrent series of patellar reflexes, generated in a feedback circuit. The effect of each contraction is fed back as a modification of tension to the calf muscle. This change of tension triggers the next patellar
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Although the two proposed mechanisms are very different in and are still debated, some studies now propose the potential of both mechanisms co-existing to create clonus. It is thought that the
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Clonus is most commonly found at the ankle, specifically with a dorsiflexion/plantarflexion movement (up and down). Some case studies have also reported clonus in the finger, toe, and
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muscle. Subsequent beating of the foot will result, however only a sustained clonus (5 beats or more) is considered abnormal. Clonus can also be tested in the
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Clonus, with respect to the presence of a central oscillator, functions on the theory that when the central oscillator is turned on by a
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Hilder, Joseph M.; Zev W. Rymer (September 1999). "A Stimulation Study of Reflex Instability in Spasticity: Origins of Clonus".
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tracts found in distal muscle groups. Clonus is commonly seen in the ankle but may exist in other distal structures as well.
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excitability is likely accomplished by alterations to the net inhibition of neurons occurring as a result of injury to the
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would be more readily conducted, and thus turn on this central oscillator. This theory is still being investigated.
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of clonus beats have been found to be directly proportional to the length of the reflex pathway it is found in.
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Douglas, Wallace M.; Bruce H Ross; Christine K. Thomas (Aug 25, 2005). "Motor unit behaviour during clonus".
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In the text, Bateson goes on to describe induction of clonus as a key element of Balinese ritual.
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on average, and may last a few seconds to several minutes depending on the patient's condition.
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is tested by rapidly flexing the foot into dorsiflexion (upward), inducing a stretch to the
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pathway may be stimulated first, and through its events, cause a decreased
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involving descending motor pathways, and in many cases is accompanied by
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pathology), clonus causes large motions that are usually initiated by a
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Set of involuntary and rhythmic muscular contractions and relaxations
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drugs, where clonus strongly predicts imminent serotonin toxicity (
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in the ankle (as opposed to the typical up and down motion).
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described the induction of clonus in healthy people:
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A Sacred Unity: Further Steps To An Ecology of Mind
47: 42: 682:Anthony, J; Damasceno, A; Ojjii, D (2016-05-18). 504:IEEE Transactions on Rehabilitation Engineering 397: 290:event, it will continue to rhythmically excite 200:, and in pregnant women presenting with severe 541: 539: 537: 535: 533: 497: 495: 493: 491: 489: 487: 485: 483: 481: 479: 599: 597: 595: 477: 475: 473: 471: 469: 467: 465: 463: 461: 459: 88:and relaxations. Clonus is a sign of certain 8: 757: 39: 707: 559: 92:conditions, particularly associated with 789:Video about Clonus at the knee (patella) 604:Weisenburg, Theodore H (November 1903). 172:Clonus is typically seen in people with 455: 410:Gregory Bateson, A Sacred Unity, p. 85 649:Journal of Nervous and Mental Disease 610:Journal of Nervous and Mental Disease 388:Voluntary Induction in Healthy People 242:signal delay are required. Increased 7: 212:, such as after ingestion of potent 606:"Triceps, Biceps and Finger Clonus" 345:Clonus results due to an increased 25: 115:. Studies have shown clonus beat 779:Dr. Gilman on Serotonin Toxicity 688:Cardiovascular Journal of Africa 661:10.1097/00005053-190205000-00002 622:10.1097/00005053-190311000-00003 430:Generalized tonic–clonic seizure 198:generalized tonic–clonic seizure 784:Video about Clonus at the ankle 570:10.1152/japplphysiol.00649.2005 643:Mitchell, John K. (May 1902). 384:(knee cap), towards the toes. 325:Clonus tends to co-exist with 1: 548:Journal of Applied Physiology 294:, therefore creating clonus. 119:to range from three to eight 274:structures like the ankle. 248:central nervous system (CNS) 229:Hyperactive stretch reflexes 80:is a set of involuntary and 825: 29: 731:Bateson, Gregory (1991). 32:Parts: The Clonus Horror 380:by rapidly pushing the 413: 349:excitation (decreased 190:hepatic encephalopathy 74: 700:10.5830/CVJA-2016-051 321:Clonus and spasticity 210:adverse drug reaction 72: 445:Tetanic contractions 208:. It can also be an 107:(usually caused by 335:spinal cord injury 282:Central oscillator 218:serotonin syndrome 192:. It can occur in 186:spinal cord damage 182:multiple sclerosis 109:lower motor neuron 94:upper motor neuron 75: 30:For the film, see 774: 773: 516:10.1109/86.788469 329:in many cases of 238:excitability and 70: 59: 58: 37:Medical condition 16:(Redirected from 816: 758: 747: 746: 728: 722: 721: 711: 679: 673: 672: 640: 634: 633: 601: 590: 589: 563: 554:(6): 2166–2172. 543: 528: 527: 499: 411: 351:action potential 313:excitability as 71: 40: 21: 824: 823: 819: 818: 817: 815: 814: 813: 794: 793: 775: 770: 769: 755: 750: 743: 730: 729: 725: 681: 680: 676: 642: 641: 637: 616:(11): 681–683. 603: 602: 593: 561:10.1.1.501.9581 545: 544: 531: 501: 500: 457: 453: 421: 412: 409: 393:Gregory Bateson 390: 366: 323: 284: 231: 226: 170: 129: 61: 38: 35: 28: 23: 22: 18:Clonic seizures 15: 12: 11: 5: 822: 820: 812: 811: 806: 796: 795: 792: 791: 786: 781: 772: 771: 765: 764: 762: 761:Classification 754: 753:External links 751: 749: 748: 741: 723: 694:(2): 104–110. 674: 655:(5): 260–261. 635: 591: 529: 510:(3): 327–340. 454: 452: 449: 448: 447: 442: 437: 435:Stretch reflex 432: 427: 420: 417: 407: 389: 386: 368:Clonus at the 365: 362: 322: 319: 315:nerve impulses 299:stretch reflex 283: 280: 230: 227: 225: 222: 174:cerebral palsy 169: 166: 165: 164: 162:Biceps brachii 159: 154: 144: 139:Ankle (medial 128: 125: 105:fasciculations 57: 56: 51: 45: 44: 36: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 821: 810: 809:Seizure types 807: 805: 804:Medical signs 802: 801: 799: 790: 787: 785: 782: 780: 777: 776: 768: 763: 759: 752: 744: 742:0-06-250100-3 738: 734: 727: 724: 719: 715: 710: 705: 701: 697: 693: 689: 685: 678: 675: 670: 666: 662: 658: 654: 650: 646: 639: 636: 631: 627: 623: 619: 615: 611: 607: 600: 598: 596: 592: 587: 583: 579: 575: 571: 567: 562: 557: 553: 549: 542: 540: 538: 536: 534: 530: 525: 521: 517: 513: 509: 505: 498: 496: 494: 492: 490: 488: 486: 484: 482: 480: 478: 476: 474: 472: 470: 468: 466: 464: 462: 460: 456: 450: 446: 443: 441: 438: 436: 433: 431: 428: 426: 423: 422: 418: 416: 406: 403: 396: 394: 387: 385: 383: 379: 375: 374:gastrocnemius 371: 363: 361: 359: 355: 352: 348: 343: 341: 336: 332: 328: 320: 318: 316: 312: 308: 304: 300: 295: 293: 292:motor neurons 289: 281: 279: 277: 273: 269: 265: 262: 257: 253: 249: 245: 241: 237: 228: 223: 221: 219: 215: 211: 207: 203: 202:pre-eclampsia 199: 196:as part of a 195: 191: 187: 183: 179: 175: 167: 163: 160: 158: 157:Triceps surae 155: 152: 148: 145: 142: 141:gastrocnemius 138: 137: 136: 134: 126: 124: 122: 118: 114: 110: 106: 102: 98: 95: 91: 87: 83: 79: 55: 52: 50: 46: 41: 33: 19: 732: 726: 691: 687: 677: 652: 648: 638: 613: 609: 551: 547: 507: 503: 414: 401: 398: 391: 367: 347:motor neuron 344: 324: 311:motor neuron 296: 285: 244:motor neuron 236:motor neuron 232: 214:serotonergic 171: 130: 90:neurological 86:contractions 77: 76: 73:Ankle clonus 340:muscle tone 256:spinal cord 798:Categories 451:References 327:spasticity 288:peripheral 101:spasticity 669:145648718 630:143749312 556:CiteSeerX 425:Myoclonus 364:Diagnosis 354:threshold 307:threshold 276:Frequency 224:Mechanism 206:eclampsia 133:laterally 117:frequency 84:muscular 54:Neurology 49:Specialty 718:27213858 578:16099891 524:10498378 419:See also 408:—  405:reflex.) 305:current 303:synaptic 194:epilepsy 151:knee cap 82:rhythmic 709:4928160 586:8598394 382:patella 268:muscles 147:Patella 97:lesions 739:  716:  706:  667:  628:  584:  576:  558:  522:  440:Tetany 402:clonus 358:reflex 331:stroke 272:distal 264:joints 261:distal 252:stroke 178:stroke 113:reflex 78:Clonus 43:Clonus 665:S2CID 626:S2CID 582:S2CID 378:knees 370:ankle 240:nerve 168:Cause 127:Signs 737:ISBN 714:PMID 574:PMID 520:PMID 333:and 266:and 204:and 188:and 704:PMC 696:doi 657:doi 618:doi 566:doi 512:doi 220:). 800:: 712:. 702:. 692:27 690:. 686:. 663:. 653:29 651:. 647:. 624:. 614:30 612:. 608:. 594:^ 580:. 572:. 564:. 552:99 550:. 532:^ 518:. 506:. 458:^ 254:/ 184:, 180:, 176:, 121:Hz 767:D 745:. 720:. 698:: 671:. 659:: 632:. 620:: 588:. 568:: 526:. 514:: 508:7 250:( 153:) 149:( 143:) 34:. 20:)

Index

Clonic seizures
Parts: The Clonus Horror
Specialty
Neurology
rhythmic
contractions
neurological
upper motor neuron
lesions
spasticity
fasciculations
lower motor neuron
reflex
frequency
Hz
laterally
gastrocnemius
Patella
knee cap
Triceps surae
Biceps brachii
cerebral palsy
stroke
multiple sclerosis
spinal cord damage
hepatic encephalopathy
epilepsy
generalized tonic–clonic seizure
pre-eclampsia
eclampsia

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