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in identifying potential carriers. If CA is identified in a herd, bulls that have tested negative for CA should be purchased, since both parents must be carriers of the defective gene for affected calves to be born. Angus sires which carry CA include
78:. As the calf grows, signs significantly improve. In mildly affected calves, CA may be less obvious, presenting as tall stature, joint laxity and poor muscling. Joint laxity predisposes affected cattle to the early onset of arthritis.
38:. The disorder affects the connective tissue of muscles, leading to contracture of the upper limb (most obvious in the hind limbs), and laxity of the joints of the lower limbs. CA affects
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Affected calves are usually born alive with normal body weight, and most can walk and suckle, although 20 percent cannot suckle and die soon after birth. Signs include
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90:, a cow born in Indiana, US, in 1978. This cow is an ancestor of approximately half of all Angus cattle in Australia, limiting the usefulness of
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Tammen, I.; Khatkar, M.S.; Cavanagh, J.A.L.; Windsor, P.A.; Thomson, P.C.; Raadsma, H.W. (2011).
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in 1998, and has since been identified in other countries. A genetic test was developed in 2010.
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230:"OMIA 001511-9913 : Contractural arachnodactyly (Fawn calf syndrome) in
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Association for the
Advancement of Animal Breeding and Genetics
264:"Mapping of congenital contractural arachnodactyly in cattle"
46:. The mutation which causes this defect is a deletion on
199:"Congenital contractural arachnodactyly in Angus cattle"
208:. No. 1015. NSW Department of Primary Industries
86:In Australia, affected animals are descended from
161:. Department of Large Animals Clinical Sciences,
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238:Online Mendelian Inheritance in Animals
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17:Congenital contractural arachnodactyly
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123:The disorder was first identified in
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299:Systemic connective tissue disorders
156:"Heritable birth defects in cattle"
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197:Denholm, Laurence (May 2010).
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88:Freestate Barbara 871 of Kaf
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163:University of Tennessee
154:Whitlock, Brian K.
125:Victoria, Australia
113:Boyd On Target 1083
76:congenital kyphosis
29:autosomal recessive
109:SAF 598 Bando 5175
105:Bon View Bando 598
101:Te Mania Kelp K207
25:fawn calf syndrome
97:Rambo 465T of JRS
92:pedigree analysis
48:bovine chromosome
23:), also known as
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165:. Archived from
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32:genetic disorder
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72:hyperextension
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54:Clinical signs
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172:on 2018-10-06
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241:. Retrieved
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210:. Retrieved
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167:the original
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44:Murray Greys
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64:contracture
288:Categories
277:: 215–218.
243:2018-03-10
232:Bos taurus
212:2018-03-10
176:2013-11-05
131:References
82:Prevention
236:. OMIA -
206:PRIMEFACT
60:proximal
27:, is an
119:History
68:distal
36:cattle
267:(PDF)
202:(PDF)
170:(PDF)
159:(PDF)
70:limb
62:limb
40:Angus
111:and
74:and
50:21.
34:in
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275:19
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252:^
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21:CA
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19:(
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