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plausible and suitably detailed recent evolutionary history of the virus, the identity and provenance of its most recent ancestors, and surprisingly, the place, time, and mechanism of transmission of the first human infection", and that natural and laboratory-associated "spillover" scenarios both remained plausible. He and colleagues in 2021 urged that greater clarity about the origins of the pandemic is necessary for anticipating the next pandemic and feasible.
255:. He was an early pioneer in the study of the human microbiome using these and other modern molecular methods, and published some of the first broad molecular surveys of the human oral and gut microbiota. His current research seeks to elucidate the nature and basis of diversity, assembly, stability and resilience in the human microbial ecosystem, and their relationships with health and disease. Relman became the
348:
In 2020, Relman called for an objective, dispassionate, and transparent investigation into the origins of COVID-19 and SARS-CoV-2, noting that despite many strongly-worded opinions and assertions about the likelihood of various hypotheses, "the 'origin story' is missing many key details, including a
1101:
Bloom, Jesse D.; Chan, Yujia Alina; Baric, Ralph S.; Bjorkman, Pamela J.; Cobey, Sarah; Deverman, Benjamin E.; Fisman, David N.; Gupta, Ravindra; Iwasaki, Akiko; Lipsitch, Marc; Medzhitov, Ruslan (2021-05-14). Sills, Jennifer (ed.).
345:... appears to be the most plausible mechanism in explaining these cases among those that the committee considered" but that "each possible cause remains speculative" and that "the report should not be viewed as conclusive".
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1020:
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at the
National Academy of Medicine from 2007-2017, and a member of the Committee on Science, Technology and Law from 2012-2015 at the National Academies of Science (NAS). He is currently a member of the
274:. He serves as the Chief of Infectious Disease at the Veterans Affairs Palo Alto Health Care System. Relman has also served in a number of United States government advisory capacities, particularly on
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and soon thereafter became interested in the discovery and identification of previously-unrecognized microbial pathogens. The problem of differentiating novel pathogens from normal
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232:, the diversity of the indigenous microbiota, and the relationship of the latter with human health and disease, formed the basis of his subsequent research career.
1028:, Standing Committee to Advise the Department of State on Unexplained Health Effects on U.S. Government Employees and Their Families at Overseas Embassies, of the
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methods for revealing novel microbial pathogens led to the identification of several important previously-uncharacterized human pathogens, including the agents of
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Eckburg, Paul; Bik, Elisabeth; Bernstein, Charles; Purdom, Elizabeth; Dethlefsen, Les; Sargent, Michael; Gill, Steven; Nelson, Karen; Relman, David (2005).
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unexplained clinical signs, symptoms, and findings amongst personnel and their families working for the U.S. Department of State in Havana
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719:"Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation"
1018:
Consensus Study Report: An
Assessment of Illness in U.S. Government Employees and Their Families at Overseas Embassies
484:
375:
240:
Relman joined the faculty at
Stanford University in 1994 and has remained there since. His development of broad range
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833:
Costello, Elizabeth K.; Stagaman, Keaton; Dethlefsen, Les; Bohannan, Brendan J. M.; Relman, David A. (2012-06-08).
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660:"The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing"
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189:
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Palmer, Chana; Bik, Elisabeth M.; DiGiulio, Daniel B.; Relman, David A.; Brown, Patrick O. (2007-06-26).
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and microbial ecosystem—for which he was a pioneer in the use of modern molecular methods, as well as on
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Relman was born in Boston, raised in
Lexington, MA, and then moved to Philadelphia where he attended
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378:, and served as its Chief Medical Officer for about a decade 2006. In the 1990s he was featured on
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and Joan M. Merigan
Professor in Medicine, and in Microbiology & Immunology at the
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835:"The Application of Ecological Theory Toward an Understanding of the Human Microbiome"
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970:"'Havana Syndrome' likely caused by pulsed microwave energy, government study finds"
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for his work there, and he served as MTV's medical correspondent from 1995 to 1997.
778:"An ecological and evolutionary perspective on human–microbe mutualism and disease"
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Dethlefsen, Les; Huse, Sue; Sogin, Mitchell L.; Relman, David A. (2008-11-18).
208:. He completed his infectious diseases and microbiology research training as a
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Dethlefsen, Les; McFall-Ngai, Margaret; Relman, David A. (October 2007).
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1044:"To stop the next pandemic, we need to unravel the origins of COVID-19"
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at
Stanford from 2013-2017 and he is currently a senior fellow at the
968:
Breslauer, Brenda; Dilanian, Ken; Lederman, Josh (December 5, 2020).
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45:
1000:"'Havana syndrome' likely caused by directed microwaves - US report"
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Science and
Security Board of the Bulletin of the Atomic Scientists
193:
379:
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301:(2006) and the Transformative Research Award (2013) from the
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293:(National Academy of Medicine) in 2011, and a member of the
1159:"Dr. Arnold Relman, 91; ex-N.E. Journal of Medicine editor"
371:
485:"Bacterial diversity within the human subgingival crevice"
1030:
National
Academies of Sciences, Engineering, and Medicine
331:
National
Academies of Sciences, Engineering, and Medicine
204:, and a clinical infectious diseases fellowship year at
601:"Development of the Human Infant Intestinal Microbiota"
891:"Center for International Security and Cooperation"
544:"Diversity of the human intestinal microbial flora"
329:In 2019-20, Relman chaired a committee of the U.S.
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259:and Joan M. Merigan Professor at Stanford in 2009.
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105:
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66:
52:
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463:Freeman Spogli Institute for International Studies
268:Freeman Spogli Institute for International Studies
264:Center for International Security and Cooperation
717:Dethlefsen, Les; Relman, David A. (2011-03-15).
262:Relman served as the science co-director of the
1048:Proceedings of the National Academy of Sciences
723:Proceedings of the National Academy of Sciences
916:"IDSA: Career Paths in ID - Academic Medicine"
483:Kroes, Ian; Lepp, Paul; Relman, David (1999).
8:
1262:Massachusetts Institute of Technology alumni
938:
936:
434:"David Relman: Featured Scientist Interview"
196:degree, magna cum laude in 1982. He did his
1272:Members of the National Academy of Medicine
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29:
18:
1238:with David Relman on the human microbiome
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370:Relman was a long-time volunteer for the
337:and in China. The committee concluded in
305:. He has served as the president of the
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295:American Academy of Arts & Sciences
220:. He began his independent career as a
412:Stanford University School of Medicine
307:Infectious Diseases Society of America
272:Center for Innovation in Global Health
150:Stanford University School of Medicine
110:Stanford University School of Medicine
1183:Moretti, M. Mindy (29 October 1995).
1104:"Investigate the origins of COVID-19"
7:
316:Intelligence Community Studies Board
152:. His research focuses on the human
281:Relman was elected a fellow of the
224:with a research focus in microbial
184:and graduated in 1977. He attended
980:from the original on March 3, 2021
14:
61:Harvard University Medical School
1282:Germantown Friends School alumni
1157:Marquard, Bryan (17 June 2014).
341:that, "Overall, directed pulsed
283:American Academy of Microbiology
1042:Relman, David A. (2020-11-24).
432:Taubes, Gary (September 2009).
364:New England Journal of Medicine
357:Relman is the son of the late
326:at the Department of Defense.
206:Massachusetts General Hospital
1:
1267:Harvard Medical School alumni
303:National Institutes of Health
180:. He was an undergraduate at
677:10.1371/journal.pbio.0060280
618:10.1371/journal.pbio.0050177
1257:Stanford University faculty
729:(supplement_1): 4554–4561.
376:Haight Ashbury Free Clinics
1298:
920:Infectious Disease Society
311:Forum on Microbial Threats
297:in 2022. He received the
1023:December 9, 2020, at the
374:program organized by the
361:, longtime editor of the
309:in 2012-13, chair of the
289:in 2010, a member of the
285:in 2003, a fellow of the
178:Germantown Friends School
115:
88:
28:
1252:American microbiologists
895:Freeman Spogli Institute
510:10.1073/pnas.96.25.14547
489:Proc Natl Acad Sci U S A
1210:"David A. Relman, M.D."
1120:10.1126/science.abj0016
1061:10.1073/pnas.2021133117
851:10.1126/science.1224203
736:10.1073/pnas.1000087107
568:10.1126/science.1110591
16:American microbiologist
1236:MicrobeWorld Interview
249:bacillary angiomatosis
190:Harvard Medical School
324:Defense Science Board
291:Institute of Medicine
82:Institute of Medicine
1189:The Washington Post
1054:(47): 29246–29248.
1006:. December 6, 2020.
845:(6086): 1255–1262.
794:10.1038/nature06245
560:2005Sci...308.1635E
501:1999PNAS...9614547K
359:Arnold "Bud" Relman
222:physician-scientist
218:Stanford University
210:postdoctoral fellow
138:David Arnold Relman
70:Study of the human
245:gene amplification
242:small subunit rRNA
160:discovery and the
788:(7164): 811–818.
408:"David A. Relman"
253:Whipple's disease
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90:Scientific career
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438:ScienceWatch
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226:pathogenesis
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106:Institutions
100:Microbiology
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611:(7): e177.
276:biosecurity
1246:Categories
386:References
339:its report
322:, and the
230:microbiota
198:internship
168:response.
154:microbiome
72:microbiome
1218:24 August
1194:24 August
1168:24 August
1144:234487267
1128:0036-8075
1070:0027-8424
953:24 August
925:24 August
900:24 August
859:0036-8075
802:1476-4687
745:0027-8424
686:1545-7885
627:1545-7885
468:24 August
443:24 August
417:24 August
343:RF energy
257:Thomas C.
202:residency
172:Education
146:Thomas C.
127:.stanford
1136:33986172
1088:33144498
1021:Archived
1004:BBC News
978:Archived
974:NBC News
877:22674335
820:17943117
763:20847294
704:19018661
645:17594176
586:15831718
529:10588742
278:issues.
270:and the
162:genomics
158:pathogen
144:and the
1108:Science
1079:7703598
1032:(2020).
868:4208626
839:Science
811:9464033
754:3063582
695:2586385
636:1896187
577:1395357
556:Bibcode
548:Science
497:Bibcode
251:and of
188:at the
120:Website
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125:relman
96:Fields
84:(2011)
78:Awards
46:Boston
1140:S2CID
520:24473
212:with
1220:2016
1196:2016
1170:2016
1132:PMID
1124:ISSN
1084:PMID
1066:ISSN
986:2021
955:2016
927:2016
902:2016
873:PMID
855:ISSN
816:PMID
798:ISSN
759:PMID
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700:PMID
682:ISSN
641:PMID
623:ISSN
582:PMID
525:PMID
470:2016
445:2016
419:2016
194:M.D.
166:host
129:.edu
41:Born
1116:doi
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1074:PMC
1056:doi
1052:117
863:PMC
847:doi
843:336
806:PMC
790:doi
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731:doi
727:108
690:PMC
672:doi
631:PMC
613:doi
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564:doi
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515:PMC
505:doi
380:MTV
216:at
182:MIT
164:of
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