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Denis Baylor is known for work on early steps in vision, in particular the mechanism in which light energy is converted to neural signals within the rod and cone photoreceptor cells of the eye. He provided a quantitative description of the laws that govern the process. Using a new method for
301:. He is known for his research on nerve cells in the retina of the eye. He developed a widely-used method for observing the electrical activity of single rod and cone photoreceptor cells and described how they encode light stimuli. Baylor’s work has been recognized by his election to the
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between 1975 and 1978. In 1978, he became a professor of neurobiology at
Stanford and chaired the Department from 1992-1995. He became Emeritus in 2001. During his career, Baylor has served on the editorial board for
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recording the electrical currents of individual cells he recorded for the first time the response of retinal rods to single photons of light and showed that the response is remarkably reproducible.
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Xu, Jun; Dodd, Robert L.; Makino, Clint L.; Simon, Melvin I.; Baylor, Denis A.; Chen, Jeannie (October 1997). "Prolonged photoresponses in transgenic mouse rods lacking arrestin".
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Chen, J.; Makino, C.; Peachey, N.; Baylor, D.; Simon, M. (January 20, 1995). "Mechanisms of rhodopsin inactivation in vivo as revealed by a COOH-terminal truncation mutant".
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His work revealed how light and color are initially encoded in the primate retina, providing a physiological basis for psychophysical results of Stiles on human vision.
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He also described and defined the molecular mechanism of two components of intrinsic photoreceptor noise that limit our ability to detect very dim light.
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He also helped to elucidate the molecular mechanism of a number of the steps that mediate and control the photoreceptor’s electrical response to light.
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374:. In 1974 he moved to Stanford University, where he was an associate professor of physiology up to 1975. Baylor was then an associate professor of
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421:. He served on the Visual Sciences Study Section of the NIH, which he chaired, as well as the advisory boards of multiple other foundations.
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Mendez, Ana; Burns, Marie E.; Roca, Angela; Lem, Janis; Wu, Lan-Wing; Simon, Melvin I.; Baylor, Denis A.; Chen, Jeannie (October 2000).
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for two years in the laboratory of M.G.F. Fuortes. From 1970 to 1972 he was a
Special Fellow of the USPHS in the laboratory of
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Zimmerman, A. L.; Baylor, D. A. (May 1986). "Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores".
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in 1961, where he graduated magna cum laude and was elected to Phi Beta Kappa. In 1965, Baylor received his M.D. from
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Schnapf, J. L.; Kraft, T. W.; Baylor, D. A. (January 1987). "Spectral sensitivity of human cone photoreceptors".
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297:(January 30, 1940 – March 16, 2022) was an American neurobiologist. He was professor emeritus of neurobiology at
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Baylor died of cardiac arrhythmia at the
Stanford Golf Course on March 16, 2022, at the age of 82.
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1102:"The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis"
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1461:"Rapid and Reproducible Deactivation of Rhodopsin Requires Multiple Phosphorylation Sites"
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medical honor society and graduated cum laude. At Yale, he was a postdoctoral fellow in
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Burns, Marie E.; Mendez, Ana; Chen, Jeannie; Baylor, Denis A. (September 2002).
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1404:"Origin of Reproducibility in the Responses of Retinal Rods to Single Photons"
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947:"Two components of electrical dark noise in toad retinal rod outer segments"
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Baylor's work has been honored by various awards, including election to the
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409:. He served on the Scientific Advisory and Medical Advisory Boards of the
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413:, where he was also a Senior Scientific Officer. He was a member of the
751:"The electrical response of turtle cones to flashes and steps of light"
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702:"Detection and resolution of visual stimuli by turtle photoreceptors"
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653:"Electrical responses of single cones in the retina of the turtle"
1202:"Spectral sensitivity of cones of the monkey Macaca fascicularis"
996:"Molecular origin of continuous dark noise in rod photoreceptors"
800:"Changes in time scale and sensitivity in turtle photoreceptors"
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Baylor, D. A.; Hodgkin, A. L.; Lamb, T. D. (November 1, 1974).
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1053:"Origin and Functional Impact of Dark Noise in Retinal Cones"
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with John
Nicholls from 1965 and 1968. He then joined the
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Members of the United States
National Academy of Sciences
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Baylor, D A; Nunn, B J; Schnapf, J L (December 1, 1984).
560:"Denis Aristide Baylor. 30 January 1940 — 16 March 2022"
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Baylor, D A; Nunn, B J; Schnapf, J L (September 1987).
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In 1972 Baylor joined the faculty of the
University of
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Fellows of the
American Academy of Arts and Sciences
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Baylor, D A; Matthews, G; Yau, K W (December 1980).
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Biographical
Memoirs of Fellows of the Royal Society
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AAAS Award for
Scientific Freedom and Responsibility
849:"The membrane current of single rod outer segments"
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1510:"Dynamics of Cyclic GMP Synthesis in Retinal Rods"
798:Baylor, D. A.; Hodgkin, A. L. (November 1, 1974).
651:Baylor, D. A.; Fuortes, M. G. F. (March 1, 1970).
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700:Baylor, D. A.; Hodgkin, A. L. (October 1, 1973).
896:Baylor, D A; Lamb, T D; Yau, K W (March 1979).
1674:Stanford University School of Medicine faculty
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898:"Responses of retinal rods to single photons"
8:
1051:Rieke, Fred; Baylor, Denis A. (April 2000).
847:Baylor, DA; Lamb, TD; Yau, KW (March 1979).
506:"Denis Baylor's Profile | Stanford Profiles"
425:Research interests and selected publications
558:Lamb FRS, Trevor D.; Yau, King-Wai (2024).
325:. Baylor received his BA in chemistry from
603:https://profiles.stanford.edu/denis-baylor
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417:Jury and was on the Visiting Committee at
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282:Learn how and when to remove this message
1402:Rieke, F.; Baylor, D.A. (October 1998).
321:Baylor was born on January 30, 1940, in
994:Rieke, F; Baylor, D A (November 1996).
632:from the original on September 19, 2020
476:
370:, where he was associate professor of
218:Please improve this article by adding
1608:from the original on January 26, 2023
1578:from the original on January 31, 2020
601:Baylor, Denis "Curriculum Vitae" via
449:American Academy of Arts and Sciences
303:American Academy of Arts and Sciences
163:University of Colorado Medical School
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343:United States Public Health Service
16:American neurobiologist (1940–2022)
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411:Howard Hughes Medical Institute
1664:Knox College (Illinois) alumni
1659:Yale School of Medicine alumni
1218:10.1113/jphysiol.1987.sp016691
1118:10.1113/jphysiol.1984.sp015518
963:10.1113/jphysiol.1980.sp013529
914:10.1113/jphysiol.1979.sp012716
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816:10.1113/jphysiol.1974.sp010732
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718:10.1113/jphysiol.1973.sp010340
669:10.1113/jphysiol.1970.sp009049
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1527:10.1016/s0896-6273(02)00911-x
1478:10.1016/s0896-6273(00)00093-3
1428:10.1016/S0006-3495(98)77625-8
1070:10.1016/s0896-6273(00)81148-4
1020:10.1016/S0006-3495(96)79448-1
622:"1996 | The Grass Foundation"
347:National Institutes of Health
220:secondary or tertiary sources
168:National Institutes of Health
1649:Fellows of the Royal Society
453:National Academy of Sciences
307:National Academy of Sciences
122:National Academy of Sciences
1669:People from Oskaloosa, Iowa
406:The Journal of Neuroscience
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1598:"Denis A. Baylor Obituary"
608:December 13, 2019, at the
394:Journal of Neurophysiology
333:, where he was elected to
1206:The Journal of Physiology
1106:The Journal of Physiology
951:The Journal of Physiology
902:The Journal of Physiology
853:The Journal of Physiology
804:The Journal of Physiology
755:The Journal of Physiology
706:The Journal of Physiology
657:The Journal of Physiology
382:The Journal of Physiology
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534:"Search | Royal Society"
317:Early life and education
106:Royal Society of London
1558:"Denis Aristide Baylor"
1322:10.1126/science.7824934
626:www.grassfoundation.org
457:Royal Society of London
368:Colorado Medical School
353:in Cambridge, England.
331:Yale School of Medicine
311:Royal Society of London
577:10.1098/rsbm.2023.0033
419:Harvard Medical School
207:relies excessively on
510:profiles.stanford.edu
295:Denis Aristide Baylor
35:Denis Aristide Baylor
68:Stanford, California
1420:1998BpJ....75.1836R
1408:Biophysical Journal
1365:1997Natur.389..505X
1314:1995Sci...267..374C
1263:1986Natur.321...70Z
1163:1987Natur.325..439S
1012:1996BpJ....71.2553R
1000:Biophysical Journal
400:Visual Neuroscience
357:Research and career
299:Stanford University
158:Stanford University
89:Yale Medical School
1604:. March 22, 2022.
345:and worked at the
1602:The Register-Mail
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443:Awards and honors
335:Alpha Omega Alpha
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1610:. Retrieved
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145:Neurobiology
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83:Knox College
62:(2022-03-16)
25:Denis Baylor
18:
1639:2022 deaths
1634:1940 births
1612:January 26,
1212:: 145–160.
957:: 591–621.
908:: 613–634.
859:: 589–611.
1628:Categories
471:References
372:Physiology
339:physiology
309:, and the
272:April 2021
242:newspapers
209:references
41:1940-01-30
636:March 31,
543:March 29,
515:March 29,
1606:Archived
1582:April 4,
1576:Archived
1544:17139873
1536:12367508
1495:15566399
1487:11086991
1338:27810310
1187:11399054
1087:14446202
1079:10798402
630:Archived
606:Archived
459:(2003).
1446:9746525
1437:1299855
1416:Bibcode
1389:4419718
1381:9333241
1361:Bibcode
1330:7824934
1310:Bibcode
1302:Science
1287:4371641
1279:2422559
1259:Bibcode
1236:3443931
1227:1192171
1179:3808045
1159:Bibcode
1136:6512705
1127:1193276
1038:8913594
1029:1233743
1008:Bibcode
981:6788941
972:1274605
923:1281447
874:1281446
834:4449053
825:1330660
785:4449052
776:1330659
736:4766219
727:1350657
687:4100807
678:1348693
256:scholar
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685:
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403:, and
388:Neuron
305:, the
258:
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244:
237:
229:
141:Fields
125:(1993)
117:(1992)
109:(2003)
99:Awards
91:(M.D.)
70:, U.S.
51:, U.S.
1540:S2CID
1491:S2CID
1385:S2CID
1334:S2CID
1283:S2CID
1183:S2CID
1083:S2CID
463:Death
263:JSTOR
249:books
1614:2023
1584:2020
1532:PMID
1483:PMID
1442:PMID
1377:PMID
1326:PMID
1275:PMID
1232:PMID
1175:PMID
1132:PMID
1075:PMID
1034:PMID
977:PMID
928:PMID
879:PMID
830:PMID
781:PMID
732:PMID
683:PMID
638:2020
545:2021
517:2021
235:news
85:(BA)
57:Died
31:Born
1522:doi
1473:doi
1432:PMC
1424:doi
1369:doi
1357:389
1318:doi
1306:267
1267:doi
1255:321
1222:PMC
1214:doi
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1167:doi
1155:325
1122:PMC
1114:doi
1110:357
1065:doi
1024:PMC
1016:doi
967:PMC
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918:PMC
910:doi
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869:PMC
861:doi
857:288
820:PMC
812:doi
808:242
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