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adverse effects. Tolerability, however, is often relative to the severity of the medical condition a drug is designed to treat. For instance, cancer patients may tolerate significant pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache, are less likely to.
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of a drug can be tolerated by a patient. Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study. Usually, it is measured by the rate of "dropouts", or patients that forfeit participation in a study due to extreme
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effects, whereas newer antidepressants have far fewer adverse effects and are well tolerated.
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147:(TCAs) are very poorly tolerated and often produce severe side effects including
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Degree to which overt adverse effects of a drug can be tolerated by a patient
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Ton, Nu Thanh Huyen; Hartstra, Jan; Persiani, Stefano; Beckert, Michael.
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60:. Unsourced material may be challenged and removed.
162:Drug tolerability should not be confused with
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120:Learn how and when to remove this message
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766:Physical medicine and rehabilitation
135:refers to the degree to which overt
58:adding citations to reliable sources
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1902:. You can help Knowledge (XXG) by
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902:Medical Scientist Training Program
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1849:Minimum inhibitory concentration
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1789:WHO list of essential medicines
1282:Non-specific effect of vaccines
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45:needs additional citations for
1844:Antimicrobial pharmacodynamics
892:Doctor of Osteopathic Medicine
326:Oral and maxillofacial surgery
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1769:Functional analog (chemistry)
1322:Hill equation (biochemistry)
872:Bachelor of Medical Sciences
639:Neurosurgical anesthesiology
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1837:Antimicrobial pharmacology
1317:Dose–response relationship
1247:Desensitization (medicine)
1759:Coinduction (anesthetics)
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1797:Tolerance and resistance
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634:Obstetric anesthesiology
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314:Digestive system surgery
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1337:Cheng-Prussoff Equation
1332:Del Castillo Katz model
1259:Other effects of ligand
1242:Receptor (biochemistry)
1160:Irreversible antagonist
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671:Mass gathering medicine
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200:"Safety - Tolerability"
153:orthostatic hypotension
1898:-related article is a
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54:improve this article
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1652:Pharmacoinformatics
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1227:Mechanism of action
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206:. David W.A. Bourne
1954:Pharmacology stubs
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1684:Pharmacotoxicology
1585:Psychopharmacology
1377:Intrinsic activity
1277:Pleiotropy (drugs)
1198:Agonist-antagonist
1110:Endogenous agonist
930:Molecular oncology
887:Doctor of Medicine
877:Master of Medicine
794:Radiation oncology
666:Emergency medicine
619:Addiction medicine
586:Clinical chemistry
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1640:Biochemistry
1564:Neuroscience
1512:Distribution
1442:Loading dose
1125:Superagonist
1082:Pharmacology
950:Rural health
935:Nanomedicine
486:Rheumatology
417: /
336:Hand surgery
321:Neurosurgery
208:. Retrieved
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1864:Bactericide
1540:Compartment
1351:Patch clamp
1327:Schild plot
1020:Wikiproject
809:Venereology
754:Neonatology
651:Dermatology
506:Gynaecology
498:gynaecology
481:Pulmonology
299:Eye surgery
261:Specialties
210:13 November
176:Side effect
1943:Categories
1744:Physiology
1676:Toxicology
1568:psychology
1517:Metabolism
1507:Absorption
1501:Liberation
1343:Organ bath
1271:Functional
1150:Antagonist
1143:Inhibitory
1098:Excitatory
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768:(PM&R)
761:Phlebology
749:Pediatrics
576:Anatomical
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471:Nephrology
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444:Hepatology
429:Cardiology
419:Immunology
182:References
80:newspapers
1526:Clearance
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1341:Methods (
970:Physician
854:education
712:Neurology
707:Narcology
571:Pathology
549:Radiology
424:Angiology
388:Andrology
1644:genetics
1616:Pharmacy
1603:Medicine
1413:Affinity
1372:Efficacy
1310:Analysis
1292:Toxicity
1000:Category
476:Oncology
407:medicine
405:Internal
253:Medicine
170:See also
149:sedation
1554:Related
1497:(L)ADME
1451:Initial
1435:Metrics
1382:Potency
1365:Metrics
1267:Binding
1237:Binding
1105:Agonist
1040:Outline
1010:Commons
955:Therapy
852:Medical
415:Allergy
383:Urology
276:Surgery
94:scholar
1556:fields
1030:Portal
897:MD–PhD
155:, and
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1753:Other
1490:LADME
612:Other
101:JSTOR
87:books
1900:stub
1642:and
1566:and
1402:TD50
1398:LD50
1394:ED50
1390:IC50
1386:EC50
1188:Drug
212:2013
73:news
1499:: (
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