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Ecdysterone has been tested on mammals due to the interest in its potential hypertrophic effect. It has been found to increase hypertrophy in rats at a similar level to some
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S 1. This is proposed to be through increase of
Calcium leading to activation of Akt and protein synthesis in skeletal muscles.
553:"Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells"
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de Loof A (2006). "Ecdysteroids: the overlooked sex steroids of insects? Males: the black box".
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and 2-deoxyecdysone. These compounds are synthesized in arthropods from dietary
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177:"Control of molting in mandibulate and chelicerate arthropods by ecdysones"
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536:: CS1 maint: DOI inactive as of September 2024 (
490:"Ecdysteroids: A novel class of anabolic agents?"
431:Dinan L, Savchenko T, Whiting P (July 2001).
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321:"Ecdysteroids Information"
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27:Group of steroid hormones
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508:(inactive 2024-09-12).
181:The Biological Bulletin
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