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Thyroid dysgenesis

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53: 133:, is a form of thyroid dysgenesis in which an entire or parts of the thyroid located in another part of the body than what is the usual case. A completely ectopic thyroid gland may be located anywhere along the path of the descent of the thyroid during 153:, and may appear anywhere along its original length. Accessory thyroid tissue may be functional, but is generally insufficient for normal function if the main thyroid gland is entirely removed. 396: 156:
Lingual thyroid is 4-7 times more common in females, with symptoms developing during puberty, pregnancy or menopause. Lingual thyroid may be asymptomatic, or give symptoms such as
529: 313: 145:. If the thyroid fails to descend to even higher degree, then the resulting final resting point of the thyroid gland may be high in the neck, such as just below the 389: 382: 226:
Macchia PE, Lapi P, Krude H, et al. (May 1998). "PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis".
346: 297: 187:"A novel loss-of-function mutation in TTF-2 is associated with congenital hypothyroidism, thyroid agenesis and cleft palate" 445: 52: 422: 465: 455: 107: 103: 87: 357: 149:. Parts of ectopic thyroid tissue ("accessory thyroid tissue") can also occur, and arises from remnants of the 186: 138: 276:
emedicine > Embryology of the Thyroid and Parathyroids > Thyroid Embryology Clinical Correlations
508: 60: 275: 490: 307: 251: 95: 482: 450: 406: 293: 243: 208: 150: 99: 72: 534: 470: 235: 198: 440: 414: 137:, although it is most commonly located at the base of the tongue, just posterior to the 17: 523: 500: 255: 64: 374: 362: 146: 113:
Congenital hypothyroidism caused by thyroid dysgenesis can be associated with
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Bouquot, Brad W. Neville, Douglas D. Damm, Carl M. Allen, Jerry E. (2002).
212: 247: 338: 432: 165: 141:. In this location, an aberrant or ectopic thyroid gland is known as a 134: 91: 239: 351: 114: 378: 110:, where the thyroid is present but not functioning correctly. 98:, or severely underdeveloped. It should not be confused with 292:(2. ed.). Philadelphia: W.B. Saunders. pp. 11–12. 185:
Castanet M, Park SM, Smith A, et al. (August 2002).
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By David J Kay and Arlen D Meyers. Updated: Jan 14, 2010
328: 499: 481: 431: 413: 332: 71: 40: 35: 390: 8: 312:: CS1 maint: multiple names: authors list ( 27:Malformation or misplacement of the thyroid 397: 383: 375: 329: 51: 32: 271: 269: 267: 265: 202: 530:Congenital disorders of endocrine system 177: 305: 7: 290:Oral & maxillofacial pathology 67:images of lingular ectopic thyroid 25: 491:Congenital absence of parathyroid 1: 135:its embryological development 446:Persistent thyroglossal duct 139:foramen cecum of the tongue 551: 423:Congenital hypopituitarism 466:Thyroid dyshormonogenesis 456:Congenital hypothyroidism 164:(difficulty talking) and 160:(difficulty swallowing), 108:thyroid dyshormonogenesis 104:congenital hypothyroidism 102:, or with other forms of 88:congenital hypothyroidism 59: 50: 168:(difficulty breathing). 131:accessory thyroid gland 204:10.1093/hmg/11.17.2051 18:Ectopic thyroid tissue 509:Absent adrenal gland 407:endocrine disorders 461:Thyroid dysgenesis 84:Thyroid dysgenesis 36:Thyroid dysgenesis 517: 516: 451:Thyroglossal cyst 372: 371: 240:10.1038/ng0598-83 151:thyroglossal duct 100:iodine deficiency 81: 80: 30:Medical condition 16:(Redirected from 542: 471:Pendred syndrome 399: 392: 385: 376: 330: 318: 317: 311: 303: 285: 279: 273: 260: 259: 223: 217: 216: 206: 182: 55: 45:Thyroid agenesis 33: 21: 550: 549: 545: 544: 543: 541: 540: 539: 520: 519: 518: 513: 495: 477: 441:Thyroid disease 427: 409: 403: 373: 368: 367: 341: 327: 322: 321: 304: 300: 287: 286: 282: 274: 263: 225: 224: 220: 191:Hum. Mol. Genet 184: 183: 179: 174: 143:lingual thyroid 127:ectopic thyroid 123: 121:Ectopic thyroid 31: 28: 23: 22: 15: 12: 11: 5: 548: 546: 538: 537: 532: 522: 521: 515: 514: 512: 511: 505: 503: 497: 496: 494: 493: 487: 485: 479: 478: 476: 475: 474: 473: 468: 463: 453: 448: 443: 437: 435: 429: 428: 426: 425: 419: 417: 411: 410: 404: 402: 401: 394: 387: 379: 370: 369: 366: 365: 354: 342: 337: 336: 334: 333:Classification 326: 325:External links 323: 320: 319: 299:978-0721690032 298: 280: 261: 218: 197:(17): 2051–9. 176: 175: 173: 170: 129:, also called 122: 119: 86:is a cause of 79: 78: 75: 69: 68: 57: 56: 48: 47: 42: 38: 37: 29: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 547: 536: 533: 531: 528: 527: 525: 510: 507: 506: 504: 502: 498: 492: 489: 488: 486: 484: 480: 472: 469: 467: 464: 462: 459: 458: 457: 454: 452: 449: 447: 444: 442: 439: 438: 436: 434: 430: 424: 421: 420: 418: 416: 412: 408: 400: 395: 393: 388: 386: 381: 380: 377: 364: 360: 359: 355: 353: 349: 348: 344: 343: 340: 335: 331: 324: 315: 309: 301: 295: 291: 284: 281: 277: 272: 270: 268: 266: 262: 257: 253: 249: 245: 241: 237: 233: 229: 222: 219: 214: 210: 205: 200: 196: 192: 188: 181: 178: 171: 169: 167: 163: 159: 154: 152: 148: 144: 140: 136: 132: 128: 120: 118: 116: 111: 109: 105: 101: 97: 93: 89: 85: 77:Endocrinology 76: 74: 70: 66: 62: 58: 54: 49: 46: 43: 39: 34: 19: 460: 356: 345: 289: 283: 231: 227: 221: 194: 190: 180: 155: 142: 130: 126: 124: 112: 94:is missing, 83: 82: 65:scintigraphy 44: 483:Parathyroid 405:Congenital 234:(1): 83–6. 41:Other names 524:Categories 228:Nat. Genet 172:References 147:hyoid bone 106:, such as 90:where the 415:Pituitary 308:cite book 162:dysphonia 158:dysphagia 73:Specialty 256:33957230 213:12165566 535:Thyroid 501:Adrenal 433:Thyroid 363:D050033 248:9590296 166:dyspnea 96:ectopic 92:thyroid 61:CT scan 352:218700 296:  254:  246:  211:  252:S2CID 358:MeSH 347:OMIM 314:link 294:ISBN 244:PMID 209:PMID 115:PAX8 63:and 236:doi 199:doi 125:An 526:: 361:: 350:: 310:}} 306:{{ 264:^ 250:. 242:. 232:19 230:. 207:. 195:11 193:. 189:. 117:. 398:e 391:t 384:v 339:D 316:) 302:. 258:. 238:: 215:. 201:: 20:)

Index

Ectopic thyroid tissue

CT scan
scintigraphy
Specialty
congenital hypothyroidism
thyroid
ectopic
iodine deficiency
congenital hypothyroidism
thyroid dyshormonogenesis
PAX8
its embryological development
foramen cecum of the tongue
hyoid bone
thyroglossal duct
dysphagia
dysphonia
dyspnea
"A novel loss-of-function mutation in TTF-2 is associated with congenital hypothyroidism, thyroid agenesis and cleft palate"
doi
10.1093/hmg/11.17.2051
PMID
12165566
doi
10.1038/ng0598-83
PMID
9590296
S2CID
33957230

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