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Family history of disease is collected in case studies, which seeks if a certain disease of one family member increases the risk of that disease being passed down to others. This could be related to either genes or environmental
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studies, and to study potential modifiers of an individual's genetic risk. If a family study shows that a trait is familial, this is a necessary, but not sufficient, criterion for it to be established as genetically influenced.
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Chromosomes carry genetic information across all of it, each gene having its specific location and position. There are 40,000 to 100,000 protein coding genes across human chromosomes.
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This can occur with sex linked genes with the X or Y chromosome. Although it is more common to be inherited from the X chromosome because the Y chromosome has less genes attached.
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Ezkurdia, Iakes; Juan, David; Rodriguez, Jose Manuel; Frankish, Adam; Diekhans, Mark; Harrow, Jennifer; Vazquez, Jesus; Valencia, Alfonso; Tress, Michael L. (2014-11-15).
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Nestadt, Gerald; Samuels, Jack; Riddle, Mark; Bienvenu, O. Joseph; Liang, Kung-Yee; LaBuda, Michele; Walkup, John; Grados, Marco; Hoehn-Saric, Rudolf (2000-04-01).
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are studies of whether a disease or trait "runs in a family". In other words, they are studies aimed at detecting the presence or absence of
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Hopper, John L.; Bishop, D. Timothy; Easton, Douglas F. (October 2005). "Population-based family studies in genetic epidemiology".
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Roy, Alec; Rylander, Gunnar; Sarchiapone, Marco (December 1997). "Genetics of
Suicide.: Family Studies and Molecular Genetics".
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Familial aggregation is the practice of combing multiple data sets of different traits and/or characteristics in a family.
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Locus (loci plural) is the physical location and position of a gene or genetic marker on the chromosome.
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Genetic linkage occurs when two genes on a DNA sequence on the same chromosome are inherited together.
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is associated with greater risk. The family research design can also be used to estimate
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Association studies aimed at detecting loci with relatively small effects on risk.
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Matthews, Abigail G.; Finkelstein, Dianne M.; Betensky, Rebecca A. (2008-10-30).
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Those aimed at measuring the extent of familial aggregation for a trait
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There are three main types of family studies in genetics:
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404:. Thousand Oaks: SAGE Publications, Inc. 2008.
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