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shown to be of major clinical importance. His school of protein chemistry established the primary structure of chymotrypsin and trypsin. While studying the aminoacid sequence in polypeptide chains, Šorm, for the first time, deduced a tentative genetic code. His studies of antimetabolites of nucleic acid constituents as potential cancerostatics or virostatics led to the synthesis and determination of the mechanism of several highly active compounds, for example, 5-azacytidine and 6-azauridine. Finally, he was active in the field of insect juvenile hormones.
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In the field of bioorgamic chemistry, he advanced knowledge of sesquiterpenoids, with medium-ring molecules, and explained the structure of different isoprenoid compounds. He also initiated the study of natural peptides, especially neurohypophyseal hormones and their analogues, some of which were
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198:Šorm was the author or co-author of a large number of scientific publications and patents and was highly cited. He also co-authored several chemistry textbooks. His wife Zora was head of the Department of Biochemistry within the institute.
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and biologically active components of plants. Šorm was the founder of the
Institute for Organic Chemistry and Biochemistry of the
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In 1952 Šorm became the director of the
Institute for Organic Chemistry and Biochemistry, part of the newly established
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The institute Šorm founded now awards a medal named after the scientist. Asteroid
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František Šorm was a staunch communist and member of the
Central Committee of
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Members of the
Central Committee of the Communist Party of Czechoslovakia
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Institute of
Organic Chemistry and Biochemistry of the CAS
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Foreign associates of the
National Academy of Sciences
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116:known for synthesis of natural compounds, mainly
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80:Czech Technical University in Prague
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239:"The Restoration of František Šorm"
171:Soviet occupation of Czechoslovakia
269:About Šorm and the Šorm Foundation
254:Essays of an Information Scientist
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163:Communist Party of Czechoslovakia
152:Czechoslovak Academy of Sciences
133:Institute of Chemical Technology
122:Czechoslovak Academy of Sciences
112:– 18 November 1980) was a Czech
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145:Charles University in Prague
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215:"3993 Sorm (1988 VV5)"
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188:Professional activity
108:(28 February 1913 in
219:Minor Planet Center
274:2001-03-06 at the
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141:organic chemistry
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86:Scientific career
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52:February 18, 1913
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169:. After the
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62:(1980-11-18)
300:1980 deaths
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69:Nationality
289:Categories
280:(in Czech)
224:16 January
202:References
48:1913-02-18
178:3993 Šorm
95:Chemistry
272:Archived
242:Archived
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278:, 1994
143:at the
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110:Prague
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226:2019
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