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Frank Hu

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red meat, saturated and polyunsaturated fatty acids, iron, and dietary patterns. These findings have contributed to current public health recommendations and policies for prevention of chronic diseases. Dr. Hu's group has also identified novel biomarkers (e.g., adipokines and nutrient metabolites) and gene-environment interactions in relation to risk of obesity and diabetes by integrating cutting-edge omics technologies into epidemiological studies (Systems Epidemiology approach). In addition, Dr. Hu has been collaborating with researchers from China to study nutrition transition, metabolic phenotypes, and cardiovascular disease in Chinese populations. His researches have also extended to global nutrition, obesity and policy issues.
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Hu's research has focused on diet/lifestyle, metabolic, and genetic determinants of obesity, type 2 diabetes, and cardiovascular disease (CVD). His group has conducted detailed analyses of many dietary and lifestyle factors and risk of diabetes and CVD, including sugar-sweetened beverages, coffee,
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In 2001, Hu published a study to quantify the preventability of type 2 diabetes through diet and lifestyle, showing that up to 90% of diabetes cases can be prevented by eating a healthy diet, maintaining normal weight, exercising regularly, not smoking tobacco, and consuming alcohol moderately.
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in 2010. He served on the IOM Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries (2009-2010), and the AHA/ACC Obesity Guidelines Expert Panel (2008-2013). Dr. Hu also served on the 2015 Dietary Guidelines Advisory Committee,
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Hu is also the Director of the Epidemiology and Genetics Core of the Boston Obesity Nutrition Research Center; and co-director of the Program in Obesity Epidemiology and Prevention at the Harvard T.H. Chan School of Public Health.
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Schulze, M. B.; Manson, J. E.; Ludwig, D. S.; Colditz, G. A.; Stampfer, M. J.; Willett, W. C.; Hu, F. B. (2004). "Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women".
1748: 176:. His recent work shows that unsaturated fats, especially polyunsaturated fats, and/or high-quality carbohydrates can be used to replace saturated fats to reduce coronary heart disease risk in the 1921: 1891: 109:; born 1966) is a Chinese American nutrition and diabetes researcher. He is Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nutrition and Epidemiology at the 1936: 1752: 1638:"Resolved: There is sufficient scientific evidence that decreasing sugar-sweetened beverage consumption will reduce the prevalence of obesity and obesity-related diseases" 1896: 1906: 149: 525:
Jiang, R; Manson, JE; Meigs, JB; Ma, J; Rifai, N; Hu, FB (2004). "Body iron stores in relation to risk of type 2 diabetes in apparently healthy women".
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Li, Y; Hruby, A; Bernstein, A. M.; Ley, S. H.; Wang, D. D.; Chiuve, S. E.; Sampson, L.; Rexrode, K. M.; Rimm, E. B.; Willett, W. C.; Hu, F. B. (2015).
1168:"Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease: A Prospective Cohort Study" 282:"Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies" 110: 1931: 1926: 799:
Qi, Q; Chu, AY; Kang, JH; Jensen, MK; Curhan, GC; Pasquale, LR; Ridker, PM; Hunter, DJ; Willett, WC; Rimm, EB; Chasman, DI; Hu, FB; Qi, L (2012).
1217:"Intake of individual saturated fatty acids and risk of coronary heart disease in US men and women: two prospective longitudinal cohort studies" 172:
In 1997, he published a study showing that types of fat are more important than total amount of fat in determining risk of heart disease in the
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Cornelis, MC; Hu, FB (2012). "Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges".
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Hu has conducted extensive research on sugar-sweetened beverages and the risk of obesity, type 2 diabetes, and cardiovascular disease.
1819: 331:"Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis" 1911: 157: 652:"Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies" 1916: 1901: 1125:
Hu, F. B.; Stampfer, M. J.; Manson, J. E.; Rimm, E.; Colditz, G. A.; Rosner, B. A.; Hennekens, C. H.; Willett, W. C. (1997).
603:"Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of women" 650:
Satija, A; Bhupathiraju, SN; Rimm, EB; Spiegelman, D; Chiuve, SE; Borgi, L; Willett, WC; Manson, JE; Sun, Q; Hu, FB (2016).
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Ding, M; Satija, A; Bhupathiraju, SN; Hu, Y; Sun, Q; Han, J; Lopez-Garcia, E; Willett, W; van Dam, RM; Hu, FB (2015).
145: 703:"Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women" 1074: 934:"Exposure to the Chinese famine in early life and the risk of hyperglycemia and type 2 diabetes in adulthood" 204: 177: 173: 1886: 380:"Association of Coffee Consumption With Total and Cause-Specific Mortality in 3 Large Prospective Cohorts" 114: 1734: 1589:"Sugar-sweetened beverages and weight gain in children and adults: A systematic review and meta-analysis" 750:
Guasch-Ferré, M; Hruby, A; Toledo, E; Clish, CB; Martínez-González, MA; Salas-Salvadó, J; Hu, FB (2016).
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Malik, VS; Willett, WC; Hu, FB (2013). "Global obesity: trends, risk factors and policy implications".
429:"Red meat consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis" 1778:
Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health
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Hu, F. B.; Manson, J. E.; Stampfer, M. J.; Colditz, G; Liu, S; Solomon, C. G.; Willett, W. C. (2001).
1881: 1792:"Managing Overweight and Obesity in Adults: Systematic Evidence Review from the Obesity Expert Panel" 1491:"Sugar-sweetened and artificially sweetened beverage consumption and risk of type 2 diabetes in men" 701:
Heidemann, C; Sun, Q; van Dam, RM; Meigs, JB; Zhang, C; Tworoger, SS; Mantzoros, CS; Hu, FB (2008).
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Pan, A; Sun, Q; Bernstein, AM; Schulze, MB; Manson, JE; Stampfer, MJ; Willett, WC; Hu, FB (2012).
1055: 1687:"Fructose and Cardiometabolic Health: What the Evidence From Sugar-Sweetened Beverages Tells Us" 1540:"Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men" 983:"Potential Impact of Time Trend of Life-Style Factors on Cardiovascular Disease Burden in China" 1442:"Sugar-Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes: A meta-analysis" 1393:"Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk" 1265: 1716: 1667: 1618: 1569: 1520: 1471: 1422: 1373: 1324: 1288: 1246: 1197: 1148: 1107: 1047: 1012: 963: 914: 865: 830: 781: 732: 683: 632: 583: 542: 507: 458: 409: 360: 311: 1440:
Malik, V. S.; Popkin, B. M.; Bray, G. A.; Despres, J. -P.; Willett, W. C.; Hu, F. B. (2010).
1805: 1706: 1698: 1657: 1649: 1608: 1600: 1559: 1551: 1510: 1502: 1461: 1453: 1412: 1404: 1363: 1355: 1316: 1280: 1236: 1228: 1187: 1179: 1138: 1097: 1089: 1075:"Globalization of diabetes: The role of diet, lifestyle, and genes (The Kelly West Lecture)" 1039: 1002: 994: 953: 945: 904: 896: 857: 820: 812: 771: 763: 722: 718: 714: 673: 663: 622: 614: 573: 534: 497: 489: 448: 440: 399: 391: 350: 342: 301: 293: 195: 1538:
De Koning, L; Malik, V. S.; Kellogg, M. D.; Rimm, E. B.; Willett, W. C.; Hu, F. B. (2012).
1862: 1806:"HHS AND USDA announce the appointment of the 2015 Dietary Guidelines Advisory Committee" 1844: 1866: 1711: 1686: 1662: 1637: 1613: 1588: 1564: 1539: 1515: 1490: 1466: 1441: 1417: 1392: 1368: 1343: 1241: 1216: 1215:
Zong, G; Li, Y; Wanders, AJ; Alssema, M; Zock, PL; Willett, WC; Hu, FB; Sun, Q (2016).
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Heidemann, C; Schulze, MB; Franco, OH; van Dam, RM; Mantzoros, CS; Hu, FB (July 2008).
502: 477: 453: 428: 404: 379: 355: 330: 306: 281: 137: 1555: 1408: 618: 395: 297: 1875: 1059: 493: 885:"Systems Epidemiology: A New Direction in Nutrition and Metabolic Disease Research" 30: 752:"Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis" 668: 1143: 1126: 1702: 1183: 998: 478:"Red meat consumption and mortality: results from 2 prospective cohort studies" 128:(NAM) in 2015, one of the highest honors in the fields of health and medicine. 1773: 981:
Li, Y; Wang, DD; Ley, SH; Howard, AG; He, Y; Lu, Y; Danaei, G; Hu, FB (2016).
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Li, Y; He, Y; Qi, L; Jaddoe, VW; Feskens, EJ; Yang, X; Ma, G; Hu, FB (2010).
562:"Low-carbohydrate-diet score and the risk of coronary heart disease in women" 1604: 1506: 1391:
Malik, V. S.; Popkin, B. M.; Bray, G. A.; Després, J. P.; Hu, F. B. (2010).
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USDA/HHS. He is the principal author of a textbook on Obesity Epidemiology (
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De Koning, L; Malik, V. S.; Rimm, E. B.; Willett, W. C.; Hu, F. B. (2011).
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Ding, M; Bhupathiraju, SN; Satija, A; van Dam, RM; Hu, FB (February 2014).
1344:"Intake of sugar-sweetened beverages and weight gain: A systematic review" 1152: 816: 1284: 578: 561: 224: 1653: 1457: 1232: 1093: 949: 767: 346: 100: 1266:"Diet, lifestyle, and the risk of type 2 diabetes mellitus in women" 1127:"Dietary Fat Intake and the Risk of Coronary Heart Disease in Women" 153: 141: 329:
Ding, M; Bhupathiraju, SN; Chen, M; van Dam, RM; Hu, FB (2014).
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Halton, TL; Willett, WC; Liu, S; et al. (November 2006).
1735:"Frank Hu receives award for diabetes epidemiology research" 427:
Pan, A; Sun, Q; Bernstein, AM; et al. (October 2011).
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Malik, V. S.; Pan, A; Willett, W. C.; Hu, F. B. (2013).
801:"Sugar-sweetened beverages and genetic risk of obesity" 198:
for Outstanding Achievement in Epidemiology from the
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Huazhong University of Science and Technology alumni
238: 74: 66: 49: 37: 21: 1892:Harvard T.H. Chan School of Public Health faculty 1342:Malik, V. S.; Schulze, M. B.; Hu, F. B. (2006). 1691:Journal of the American College of Cardiology 150:Huazhong University of Science and Technology 55:Huazhong University of Science and Technology 8: 1937:Members of the National Academy of Medicine 1348:The American Journal of Clinical Nutrition 239:"Boston Nutrition Obesity Research Center" 29: 18: 1710: 1661: 1612: 1563: 1514: 1465: 1416: 1367: 1240: 1191: 1142: 1101: 1006: 957: 908: 824: 775: 726: 677: 667: 626: 577: 501: 452: 403: 354: 305: 111:Harvard T.H. Chan School of Public Health 719:10.7326/0003-4819-149-5-200809020-00005 216: 1897:Chinese emigrants to the United States 1780:. National Academies Press (US). 2010. 1593:American Journal of Clinical Nutrition 1495:American Journal of Clinical Nutrition 1907:University of Illinois Chicago alumni 7: 182:Health Professionals Follow-up Study 148:(now Tongji Medical College of the 113:, and Professor of Medicine at the 862:10.1146/annurev-nutr-071811-150648 14: 1774:"Committee and Staff Biographies" 1556:10.1161/CIRCULATIONAHA.111.067017 1409:10.1161/CIRCULATIONAHA.109.876185 619:10.1161/CIRCULATIONAHA.108.771881 396:10.1161/CIRCULATIONAHA.115.017341 298:10.1161/CIRCULATIONAHA.113.005925 158:University of Illinois at Chicago 1837: 1685:Malik, V. S.; Hu, F. B. (2015). 156:in 1988, and his Ph.D. from the 144:, Hu received his M.D. from the 1273:New England Journal of Medicine 1131:New England Journal of Medicine 494:10.1001/archinternmed.2011.2287 1932:American public health doctors 1927:Harvard Medical School faculty 105: 96: 53:University of Illinois Chicago 1: 883:Cornelis, MC; Hu, FB (2013). 200:American Diabetes Association 194:Dr. Hu is a recipient of the 669:10.1371/journal.pmed.1002039 126:National Academy of Medicine 1144:10.1056/NEJM199711203372102 267:"NAM Elects 80 New Members" 41:1966 (age 57–58) 1953: 1703:10.1016/j.jacc.2015.08.025 1184:10.1016/j.jacc.2015.07.055 999:10.1016/j.jacc.2016.06.011 901:10.1007/s13668-013-0052-4 146:Tongji Medical University 82: 59: 28: 1912:American food scientists 124:Hu was elected into the 1605:10.3945/ajcn.113.058362 1507:10.3945/ajcn.110.007922 1044:10.1038/nrendo.2012.199 445:10.3945/ajcn.111.018978 205:Oxford University Press 1917:American nutritionists 1820:"Obesity Epidemiology" 1321:10.1001/jama.292.8.927 539:10.1001/jama.291.6.711 115:Harvard Medical School 78:Harvard Medical School 1902:Scientists from Hubei 1749:"Kelly M. West Award" 1360:10.1093/AJCN/84.2.274 817:10.1056/NEJMoa1203039 44:Hubei Province, China 1285:10.1056/NEJMoa010492 579:10.1056/NEJMoa055317 178:Nurses' Health Study 174:Nurses' Health Study 16:Nutrition researcher 1550:(14): 1735–41, S1. 1847:has a profile for 1636:Hu, F. B. (2013). 1032:Nat Rev Endocrinol 1853: 1654:10.1111/obr.12040 1458:10.2337/dc10-1079 1452:(11): 2477–2483. 1233:10.1136/bmj.i5796 1172:J Am Coll Cardiol 1137:(21): 1491–1499. 1094:10.2337/dc11-0442 987:J Am Coll Cardiol 950:10.2337/db10-0385 768:10.2337/dc15-2251 572:(19): 1991–2002. 482:Arch. Intern. Med 433:Am. J. Clin. Nutr 347:10.2337/dc13-1203 253:"Obesity Program" 227:. 5 January 2021. 86: 85: 61:Scientific career 1944: 1851: 1841: 1840: 1824: 1823: 1816: 1810: 1809: 1802: 1796: 1795: 1788: 1782: 1781: 1770: 1764: 1763: 1761: 1760: 1751:. 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Med 559: 558: 554: 524: 523: 519: 475: 474: 470: 426: 425: 421: 390:(24): 2305–15. 377: 376: 372: 328: 327: 323: 279: 278: 274: 265: 264: 260: 251: 250: 246: 237: 236: 232: 223: 222: 218: 213: 166: 134: 54: 50:Alma mater 45: 42: 24: 17: 12: 11: 5: 1950: 1948: 1940: 1939: 1934: 1929: 1924: 1919: 1914: 1909: 1904: 1899: 1894: 1889: 1884: 1874: 1873: 1870: 1869: 1867:Google Scholar 1843: 1836: 1835: 1834: 1832: 1831:External links 1829: 1826: 1825: 1811: 1797: 1783: 1765: 1740: 1726: 1677: 1628: 1579: 1530: 1481: 1432: 1383: 1354:(2): 274–288. 1334: 1298: 1256: 1207: 1158: 1117: 1088:(6): 1249–57. 1065: 1022: 973: 944:(10): 2400–6. 924: 895:(4): 225–235. 875: 840: 791: 742: 707:Ann Intern Med 693: 642: 593: 552: 517: 468: 439:(4): 1088–96. 419: 370: 321: 272: 258: 244: 230: 215: 214: 212: 209: 165: 162: 138:Hubei Province 133: 130: 84: 83: 80: 79: 76: 72: 71: 68: 64: 63: 57: 56: 51: 47: 46: 43: 39: 35: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1949: 1938: 1935: 1933: 1930: 1928: 1925: 1923: 1920: 1918: 1915: 1913: 1910: 1908: 1905: 1903: 1900: 1898: 1895: 1893: 1890: 1888: 1887:Living people 1885: 1883: 1880: 1879: 1877: 1868: 1864: 1861: 1860: 1855: 1854: 1846: 1830: 1821: 1815: 1812: 1807: 1801: 1798: 1793: 1787: 1784: 1779: 1775: 1769: 1766: 1755:on 2014-10-21 1754: 1750: 1744: 1741: 1736: 1730: 1727: 1722: 1718: 1713: 1708: 1704: 1700: 1696: 1692: 1688: 1681: 1678: 1673: 1669: 1664: 1659: 1655: 1651: 1648:(8): 606–19. 1647: 1643: 1639: 1632: 1629: 1624: 1620: 1615: 1610: 1606: 1602: 1598: 1594: 1590: 1583: 1580: 1575: 1571: 1566: 1561: 1557: 1553: 1549: 1545: 1541: 1534: 1531: 1526: 1522: 1517: 1512: 1508: 1504: 1501:(6): 1321–7. 1500: 1496: 1492: 1485: 1482: 1477: 1473: 1468: 1463: 1459: 1455: 1451: 1447: 1446:Diabetes Care 1443: 1436: 1433: 1428: 1424: 1419: 1414: 1410: 1406: 1402: 1398: 1394: 1387: 1384: 1379: 1375: 1370: 1365: 1361: 1357: 1353: 1349: 1345: 1338: 1335: 1330: 1326: 1322: 1318: 1315:(8): 927–34. 1314: 1310: 1302: 1299: 1294: 1290: 1286: 1282: 1279:(11): 790–7. 1278: 1274: 1267: 1260: 1257: 1252: 1248: 1243: 1238: 1234: 1230: 1226: 1222: 1218: 1211: 1208: 1203: 1199: 1194: 1189: 1185: 1181: 1177: 1173: 1169: 1162: 1159: 1154: 1150: 1145: 1140: 1136: 1132: 1128: 1121: 1118: 1113: 1109: 1104: 1099: 1095: 1091: 1087: 1083: 1082:Diabetes Care 1076: 1069: 1066: 1061: 1057: 1053: 1049: 1045: 1041: 1037: 1033: 1026: 1023: 1018: 1014: 1009: 1004: 1000: 996: 993:(8): 818–33. 992: 988: 984: 977: 974: 969: 965: 960: 955: 951: 947: 943: 939: 935: 928: 925: 920: 916: 911: 906: 902: 898: 894: 890: 889:Curr Nutr Rep 886: 879: 876: 871: 867: 863: 859: 855: 851: 850:Annu Rev Nutr 844: 841: 836: 832: 827: 822: 818: 814: 810: 806: 802: 795: 792: 787: 783: 778: 773: 769: 765: 762:(5): 833–46. 761: 757: 756:Diabetes Care 753: 746: 743: 738: 734: 729: 724: 720: 716: 713:(5): 307–16. 712: 708: 704: 697: 694: 689: 685: 680: 675: 670: 665: 661: 657: 653: 646: 643: 638: 634: 629: 624: 620: 616: 612: 608: 604: 597: 594: 589: 585: 580: 575: 571: 567: 563: 556: 553: 548: 544: 540: 536: 532: 528: 521: 518: 513: 509: 504: 499: 495: 491: 488:(7): 555–63. 487: 483: 479: 472: 469: 464: 460: 455: 450: 446: 442: 438: 434: 430: 423: 420: 415: 411: 406: 401: 397: 393: 389: 385: 381: 374: 371: 366: 362: 357: 352: 348: 344: 341:(2): 569–86. 340: 336: 335:Diabetes Care 332: 325: 322: 317: 313: 308: 303: 299: 295: 292:(6): 643–59. 291: 287: 283: 276: 273: 268: 262: 259: 254: 248: 245: 240: 234: 231: 226: 220: 217: 210: 208: 206: 201: 197: 192: 189: 185: 183: 179: 175: 170: 163: 161: 159: 155: 151: 147: 143: 139: 131: 129: 127: 122: 118: 116: 112: 108: 102: 94: 90: 81: 77: 73: 69: 65: 62: 58: 52: 48: 40: 36: 32: 27: 20: 1850:Frank B. Hu 1849: 1814: 1800: 1786: 1777: 1768: 1757:. Retrieved 1753:the original 1743: 1729: 1694: 1690: 1680: 1645: 1641: 1631: 1596: 1592: 1582: 1547: 1543: 1533: 1498: 1494: 1484: 1449: 1445: 1435: 1400: 1396: 1386: 1351: 1347: 1337: 1312: 1308: 1301: 1276: 1272: 1259: 1224: 1220: 1210: 1175: 1171: 1161: 1134: 1130: 1120: 1085: 1081: 1068: 1038:(1): 13–27. 1035: 1031: 1025: 990: 986: 976: 941: 937: 927: 892: 888: 878: 853: 849: 843: 808: 805:N Engl J Med 804: 794: 759: 755: 745: 710: 706: 696: 659: 655: 645: 613:(3): 230–7. 610: 606: 596: 569: 565: 555: 533:(6): 711–7. 530: 526: 520: 485: 481: 471: 436: 432: 422: 387: 383: 373: 338: 334: 324: 289: 285: 275: 261: 247: 233: 219: 193: 190: 186: 171: 167: 136:A native of 135: 123: 119: 106:Hú Bǐngcháng 104: 88: 87: 75:Institutions 60: 1882:1966 births 1852:(Q18062122) 1544:Circulation 1397:Circulation 607:Circulation 384:Circulation 286:Circulation 89:Frank B. Hu 23:Frank B. 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Index


Chinese
pinyin
Harvard T.H. Chan School of Public Health
Harvard Medical School
National Academy of Medicine
Hubei Province
China
Tongji Medical University
Huazhong University of Science and Technology
Wuhan
University of Illinois at Chicago
Nurses' Health Study
Nurses' Health Study
Health Professionals Follow-up Study
Kelly West Award
American Diabetes Association
Oxford University Press
"Frank Hu"
"Boston Nutrition Obesity Research Center"
"Obesity Program"
"NAM Elects 80 New Members"
"Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies"
doi
10.1161/CIRCULATIONAHA.113.005925
PMC
3945962
PMID
24201300
"Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis"

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