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175:, "generalized lichen myxedematosus" and "sclerodermoid lichen myxedematosus") is a rare skin disease. Localized and disseminated cases are called papular mucinosis or lichen myxedematosus while generalized, confluent papular forms with
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are called scleromyxedema. Frequently, all three forms are regarded as papular mucinosis. However, some authors restrict it to only mild cases. Another form, acral persistent papular mucinosis is regarded as a separate entity.
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have also been shown to improve the conditions. All medications listed can cause adverse symptoms, with isotretinoin and etretinate particularly dangerous since they are both
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for the disease is poor. There are reported instances of remission of the disease when treated with a combination of
Revlimid and Dexamethasone over a 24-month period.
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Papular mucinosis affects adults of both sexes equally and appears between ages 30 and 80. Recently, it has been reported in patients infected with the
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layer of the skin breaks out into small and solid bumps, usually conical in shape and measured from 2 to 4 mm or sometimes flat-topped
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cells in lungs and the sensitive part of the nose. They usually come in clusters such as linear arrays. Less frequently,
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251:-like induration occurs on the skin. In addition, the mobility of the lips, hands, arms, and legs is reduced. Proximal
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is a rare neurological complication of the disease presenting with fever, seizures and altered mental status.
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aspect of the hands, face, elbows, and extensor portions of the extremities are most frequently affected.
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208:, a waxy substance of mucus, the body's natural and protective lubricant found in saliva and
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There is no effective treatment for this condition. It has been reported that clearance of
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468:"Clinicopathological Challenge: Multiple Skin-Colored Papules With Diffuse Sclerosis"
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aperistalsis, and hoarseness are among the notable systemic symptoms. If
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if you can. Unsourced or poorly sourced material may be challenged and
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In scleromyxedema, symptoms can occur on larger part of the body.
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Papular mucinosis may be divided into several types or variants:
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236:, results in longitudinal folding and gives the appearance of a
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Papular mucinosis is chronic and may be progressive. The
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Rothfleisch JE (December 2001). "Papular mucinosis".
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405:virus. It has also been associated with certain
466:Applebaum DS, Daulat S, Duvic M (August 2014).
57:Please review the contents of the article and
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529:. Malaysia. December 20, 2006. Archived from
8:
271:is involved, the disease will be fatal. The
441:Rapini RP, Bolognia JL, Jorizzo JL (2007).
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377:photochemotherapy, electron-beam therapy,
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727:Self-healing juvenile cutaneous mucinosis
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228:lesions are absent. The coalescence of
713:Discrete papular lichen myxedematosus
365:. Other attempted treatments include
325:Discrete papular lichen myxedematosus
7:
409:such as IgG lambda paraproteinemia.
718:Acral persistent papular mucinosis
295:Acral persistent papular mucinosis
25:
232:on the face, particularly on the
798:Reticular erythematous mucinosis
793:Generalized lichen myxedematosus
216:, nodular, or sometimes annular
123:
31:
18:Generalized lichen myxedematosus
723:Self-healing papular mucinosis
705:Localized lichen myxedematosus
320:Localized lichen myxedematosus
310:Cutaneous mucinosis of infancy
300:Self-healing papular mucinosis
59:add the appropriate references
1:
737:Atypical lichen myxedematosus
349:alone or in combination with
200:, these bumps do not contain
747:Nodular lichen myxedematosus
732:Papular mucinosis of infancy
523:"What is Papular mucinosis?"
484:10.1001/jamadermatol.2014.14
419:List of cutaneous conditions
315:Nodular lichen myxedematosus
305:Papular mucinosis of infancy
44:reliable medical references
856:
742:Atypical tuberous myxedema
540:Dermatology Online Journal
768:Cutaneous lupus mucinosis
763:Cutaneous focal mucinosis
443:Dermatology: 2-Volume Set
50:or relies too heavily on
783:Perifollicular mucinosis
220:may be appreciated. The
756:Other primary mucinoses
385:. However, the overall
204:. Instead they contain
261:central nervous system
273:dermatoneuro syndrome
814:Basal-cell carcinoma
697:Lichen myxedematosus
498:on December 29, 2012
445:. St. Louis: Mosby.
807:Secondary mucinoses
788:Stiff skin syndrome
73:"Papular mucinosis"
819:Granuloma annulare
633:External resources
552:10.5070/D30v13r619
827:
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778:Alopecia mucinosa
773:Eccrine mucinosis
656:
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452:978-1-4160-2999-1
341:can be done with
169:Papular mucinosis
166:
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142:Papular mucinosis
136:Medical condition
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16:(Redirected from
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494:. Archived from
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347:cyclophosphamide
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515:Further reading
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533:on 2011-06-08.
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478:(8): 893–894.
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238:leonine facies
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173:scleromyxedema
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75: –
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69:Find sources:
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40:This article
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531:the original
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500:. Retrieved
496:the original
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383:dermabrasion
371:cyclosporine
355:isotretinoin
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187:
184:Presentation
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111:
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48:verification
41:
249:scleroderma
153:Dermatology
114:August 2024
42:needs more
502:August 18,
425:References
367:interferon
363:teratogens
359:etretinate
351:prednisone
265:esophageal
263:symptoms,
214:urticarial
210:epithelial
84:newspapers
840:Mucinoses
693:Mucinosis
642:eMedicine
546:(2): 13.
393:Incidence
387:prognosis
343:melphalan
333:Treatment
279:Diagnosis
196:. Unlike
177:sclerosis
148:Specialty
834:Category
560:12165229
527:The Star
492:24919716
413:See also
369:-alpha,
253:myopathy
234:glabella
198:pustules
623:D053718
598:: L98.5
353:. Both
339:lesions
269:viscera
245:Redness
230:papules
226:Mucosal
218:lesions
194:papules
98:scholar
63:removed
558:
490:
449:
222:dorsal
190:dermal
155:
100:
93:
86:
79:
71:
612:701.8
206:mucin
105:JSTOR
91:books
618:MeSH
607:9-CM
556:PMID
504:2014
488:PMID
447:ISBN
403:AIDS
381:and
379:IVIg
375:PUVA
357:and
345:and
247:and
77:news
46:for
603:ICD
591:ICD
548:doi
480:doi
476:150
399:HIV
202:pus
836::
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595:10
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470:.
433:^
373:,
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65:.
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685:e
678:t
671:v
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583:D
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544:7
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401:/
116:)
112:(
102:·
95:·
88:·
81:·
55:.
20:)
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