43:
340:
271:. However, as different lines of research converged, it became clear that some of the same signaling proteins which the hematopoietic and immune systems use were also being used by all sorts of other cells and tissues, during development and in the mature organism.
1058:
3075:
1076:
Del Angel-Mosqueda C, Gutiérrez-Puente Y, López-Lozano AP, Romero-Zavaleta RE, Mendiola-Jiménez A, Medina-De la Garza CE, Márquez-M M, De la Garza-Ramos MA (September 2015).
2369:
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291:
4990:
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5950:
5606:
4754:
643:
4371:
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1154:
Cottler-Fox M, Klein HG (April 1994). "Transfusion support of hematology and oncology patients. The role of recombinant hematopoietic growth factors".
948:
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324:
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204:
5321:
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4000:
3611:
2731:
1403:
815:
126:
3269:
3213:
3204:
876:
1343:
286:
is a neutral term with respect to whether a molecule affects proliferation. While some cytokines can be growth factors, such as
5843:
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1689:
1618:
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666:
5930:
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4602:
4465:
1750:
1418:
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64:
60:
347:
107:
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79:
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53:
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Domouzoglou EM, Naka KK, Vlahos AP, Papafaklis MI, Michalis LK, Tsatsoulis A, Maratos-Flier E (September 2015).
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contain growth factors PDGF, IGF-1, EGF, and TGF-β which begin healing of wounds by attracting and activating
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They often promote cell differentiation and maturation, which varies between growth factors. For example,
75:
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4172:
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3095:
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5301:
4233:
4182:
2717:
1190:
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4167:
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2559:
1827:
1034:
1024:
821:
632:
316:
4092:
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Individual growth factor proteins tend to occur as members of larger families of structurally and
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5532:
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5166:
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1078:"Epidermal growth factor enhances osteogenic differentiation of dental pulp stem cells in vitro"
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100:
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For the last two decades, growth factors have been increasingly used in the treatment of
1194:
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784:
384:
208:
196:
720:– T-cell growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells.
1226:"Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21"
17:
5945:
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5217:
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295:
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42:
165:. Growth factors are important for regulating a variety of cellular processes.
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779:
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252:
240:
1298:
302:, are used as "death" signals; they cause target cells to undergo programmed
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1202:
773:
654:
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460:
374:
related proteins. There are many families, some of which are listed below:
371:
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1113:
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1167:
263:
in which cells can occur in a liquid suspension and not bound up in solid
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1004:
965:
941:
913:
853:
268:
267:, it makes sense for them to communicate by soluble, circulating protein
226:
173:
5935:
5356:
4821:
4223:
3184:
1719:
1658:
1019:
732:– Growth factor for activated B cells, resting T cells, and mast cells.
684:
659:
177:
158:
5848:
5512:
5401:
5326:
5031:
5026:
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2156:
2140:
2135:
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2125:
2120:
2110:
2105:
1273:
Gorenoi, Vitali; Brehm, Michael U.; Koch, Armin; Hagen, Anja (2017).
455:
248:
244:
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2226:
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2100:
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2028:
2023:
2018:
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2008:
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1773:
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1529:
1523:
1517:
1511:
1491:
1487:
1478:
1474:
1465:
1461:
770:(MSP), also known as hepatocyte growth factor-like protein (HGFLP)
620:
615:
610:
605:
600:
595:
590:
585:
580:
575:
570:
565:
560:
1353:
949:
skin wound healing and regeneration of other tissues such as bone
224:
is sometimes used interchangeably among scientists with the term
27:
Protein or other substance that stimulates cellular proliferation
5351:
3957:
3953:
3949:
3945:
3941:
3937:
3872:
3868:
3864:
3860:
3856:
3759:
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3592:
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3515:
3496:
3020:
2958:
2721:
2668:
2236:
2177:
2172:
1952:
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1937:
1931:
1925:
1919:
1913:
1908:
1483:
1470:
1457:
1435:
1431:
1427:
1422:
1414:
1275:"Growth factors for angiogenesis in peripheral arterial disease"
1230:
American
Journal of Physiology. Heart and Circulatory Physiology
761:
555:
544:
539:
534:
529:
524:
3057:
2962:
1847:
1357:
738:– Induces differentiation of activated B cells and eosinophils.
334:
36:
1181:
Aaronson SA (November 1991). "Growth factors and cancer".
744:– Stimulates Ig synthesis. Growth factor for plasma cells.
145:
is a naturally occurring substance capable of stimulating
1040:
Wound healing § Overview of involved growth factors
351:
5951:
Pituitary adenylate cyclase-activating peptide (PACAP)
30:"Growth factors" redirects here. For the journal, see
5818:
5605:
5500:
5269:
5009:
5000:
4980:
4894:
4871:
4840:
4809:
4778:
4742:
4733:
4585:
4428:
4361:
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3549:
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3212:
3203:
3172:
3094:
2853:
2811:
2780:
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2512:
2477:
2440:
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2304:
2289:
2280:
2190:
2165:
2149:
2052:
1901:
1892:
1885:
1820:
1782:
1749:
1686:
1655:
1644:
1609:
1581:
1539:
1500:
1444:
1400:
1391:
67:. Unsourced material may be challenged and removed.
5897:Glucose-6-phosphate isomerase (GPI; PGI, PHI, AMF)
4755:Glial cell line-derived neurotrophic factor (GDNF)
4408:Cleavage products/derivatives with unknown target:
726:– Stimulates production of all non-lymphoid cells.
5931:Macrophage-stimulating protein (MSP; HLP, HGFLP)
714:- Cofactor for IL-3 and IL-6. Activates T cells.
442:Granulocyte macrophage colony-stimulating factor
3572:Heparin-binding EGF-like growth factor (HB-EGF)
3255:Heparin-binding EGF-like growth factor (HB-EGF)
1156:Archives of Pathology & Laboratory Medicine
298:or cell proliferation. Some cytokines, such as
944:diseases and cardiovascular diseases such as:
5983:Additional growth factor receptor modulators:
3069:
2974:
1859:
1369:
231:Historically, cytokines were associated with
8:
4337:Insulin-like growth factor-2 (somatomedin A)
4219:Insulin-like growth factor-2 (somatomedin A)
4209:Insulin-like growth factor-1 (somatomedin C)
1279:The Cochrane Database of Systematic Reviews
1130:Ocular Therapeutics: Eye on New Discoveries
644:Glial cell line-derived neurotrophic factor
195:(EGF) enhances osteogenic differentiation (
5006:
4739:
4187:
3616:
3209:
3076:
3062:
3054:
2981:
2967:
2959:
2586:
2518:
2301:
2286:
1898:
1889:
1866:
1852:
1844:
1652:
1397:
1376:
1362:
1354:
1336:at the U.S. National Library of Medicine
1306:
1249:
1103:
1093:
127:Learn how and when to remove this message
5941:Migration-stimulating factor (MSF; PRG4)
207:stimulate blood vessel differentiation (
3270:Transforming growth factor alpha (TGFα)
1051:
856:(RNLS) – Anti-apoptotic survival factor
5844:Connective tissue growth factor (CTGF)
294:, others have an inhibitory effect on
172:molecules between cells. Examples are
5907:Hepatoma-derived growth factor (HDGF)
436:Granulocyte colony-stimulating factor
325:Nobel Prize in Physiology or Medicine
7:
430:Macrophage colony-stimulating factor
235:(blood and lymph forming) cells and
65:adding citations to reliable sources
401:Ciliary neurotrophic factor family
205:vascular endothelial growth factors
1127:Yorio T, Clark AF, Wax MB (2007).
897:Vascular endothelial growth factor
626:Fibroblast growth factor 23(FGF23)
621:Fibroblast growth factor 22(FGF22)
616:Fibroblast growth factor 21(FGF21)
611:Fibroblast growth factor 20(FGF20)
606:Fibroblast growth factor 19(FGF19)
601:Fibroblast growth factor 18(FGF18)
596:Fibroblast growth factor 17(FGF17)
591:Fibroblast growth factor 16(FGF16)
586:Fibroblast growth factor 15(FGF15)
581:Fibroblast growth factor 14(FGF14)
576:Fibroblast growth factor 13(FGF13)
571:Fibroblast growth factor 12(FGF12)
566:Fibroblast growth factor 11(FGF11)
561:Fibroblast growth factor 10(FGF10)
25:
816:Brain-derived neurotrophic factor
5926:Leukemia inhibitory factor (LIF)
877:Transforming growth factor alpha
750:– Growth factor for pre-B cells.
556:Fibroblast growth factor 9(FGF9)
551:Fibroblast growth factor 8(FGF8)
540:Fibroblast growth factor 6(FGF6)
535:Fibroblast growth factor 5(FGF5)
530:Fibroblast growth factor 4(FGF4)
525:Fibroblast growth factor 3(FGF3)
520:Fibroblast growth factor 2(FGF2)
515:Fibroblast growth factor 1(FGF1)
338:
168:Growth factors typically act as
41:
5094:Negative allosteric modulators:
1690:Relaxin family peptide hormones
883:Transforming growth factor beta
667:Growth differentiation factor-9
545:Fibroblast growth factor 7(FGF7
184:on the surface of their target
52:needs additional citations for
5412:Gossypetin (3,5,7,8,3',4'-HHF)
4603:Platelet-derived growth factor
1291:10.1002/14651858.CD011741.pub2
1133:. Academic Press. p. 88.
848:Platelet-derived growth factor
768:Macrophage-stimulating protein
679:Hepatoma-derived growth factor
319:(NGF) was first discovered by
1:
5618:Placental growth factor (PGF)
278:implies a positive effect on
5902:Glia maturation factor (GMF)
4411:Glypromate (GPE, (1-3)IGF-1)
1064:Dorland's Medical Dictionary
762:Migration-stimulating factor
701:Insulin-like growth factor-2
695:Insulin-like growth factor-1
1344:FGF5 in Hair Tonic Products
1242:10.1152/ajpheart.00527.2015
984:for cardiovascular diseases
891:Tumor necrosis factor-alpha
872:Transforming growth factors
690:Insulin-like growth factors
633:Foetal Bovine Somatotrophin
405:Ciliary neurotrophic factor
396:Bone morphogenetic proteins
157:. Usually it is a secreted
6029:
5834:Colony-stimulating factors
5826:Additional growth factors:
1663:Insulin-like growth factor
756:Keratinocyte growth factor
425:Colony-stimulating factors
411:Leukemia inhibitory factor
199:or bone formation), while
29:
5182:SNA-120 (pegylated K252a)
4354:(against IGF-1 and IGF-2)
4316:(against IGF-1 and IGF-2)
2996:
2829:Colony-stimulating factor
1349:FGF1 in Cosmetic Products
1095:10.1186/s13005-015-0086-5
1015:Human Genome Organisation
391:Autocrine motility factor
201:fibroblast growth factors
4018:Hepatocyte growth factor
3577:Neuregulins (heregulins)
3508:Neuregulins (heregulins)
3452:Trastuzumab duocarmazine
3165:(against angiopoietin 2)
3159:(against angiopoietin 3)
2864:proinflammatory cytokine
1338:Medical Subject Headings
1082:Head & Face Medicine
960:myelodysplastic syndrome
673:Hepatocyte growth factor
509:Fibroblast growth factor
155:cellular differentiation
32:Growth Factors (journal)
3365:Depatuxizumab mafodotin
1503:FGF homologous factors:
1203:10.1126/science.1659742
1030:Receptor (biochemistry)
842:Placental growth factor
450:Epidermal growth factor
217:Comparison to cytokines
193:epidermal growth factor
5988:(neurotrophin mixture)
5976:Wnt signaling proteins
5657:Allosteric modulators:
5377:Norwogonin (5,7,8-THF)
3597:5 (tomoregulin, TMEFF)
3447:Trastuzumab deruxtecan
3085:Growth factor receptor
1995:/PARC/DCCK1/AMAC1/MIP4
1010:Growth factor receptor
639:GDNF family of ligands
243:and tissue cells from
180:that bind to specific
5916:T-cell growth factors
4173:Telisotuzumab vedotin
3457:Trastuzumab emtansine
4501:EVT-901 (SAR-127963)
4234:Mecasermin rinfabate
1784:Vascular endothelial
860:T-cell growth factor
352:adding missing items
321:Rita Levi-Montalcini
61:improve this article
2560:Interferon type III
1195:1991Sci...254.1146A
1035:Signal transduction
1025:Neurotrophic factor
822:Nerve growth factor
317:nerve growth factor
153:, and occasionally
5667:Kinase inhibitors:
5530:Kinase inhibitors:
5429:Kinase inhibitors:
5104:Kinase inhibitors:
4919:Kinase inhibitors:
4879:Kinase inhibitors:
4860:Kinase inhibitors:
4829:Kinase inhibitors:
4798:Kinase inhibitors:
4767:Kinase inhibitors:
4627:Kinase inhibitors:
4241:Kinase inhibitors:
4035:Kinase inhibitors:
3824:Kinase inhibitors:
3817:Aprutumab ixadotin
3464:Kinase inhibitors:
3277:Kinase inhibitors:
3134:Kinase inhibitors:
3011:Granulation tissue
1000:Bone growth factor
350:; you can help by
323:, which won her a
280:cell proliferation
257:circulatory system
147:cell proliferation
5995:
5994:
5601:
5600:
5362:N-Acetylserotonin
5261:ReN-1820 (TrkAd5)
4890:
4889:
4424:
4423:
4369:Binding proteins:
4028:Dihexa (PNB-0408)
3995:
3994:
3606:
3605:
3520:6 (neuroglycan C)
3240:EGF (urogastrone)
3218:
3051:
3050:
2956:
2955:
2849:
2848:
2807:
2806:
2704:
2703:
2700:
2699:
2508:
2507:
2186:
2185:
1841:
1840:
1745:
1744:
1577:
1576:
1189:(5035): 1146–53.
1140:978-0-12-370585-3
926:endothelial cells
368:
367:
137:
136:
129:
111:
18:Growth substances
16:(Redirected from
6020:
5807:Decoy receptors:
5780:Alacizumab pegol
5258:Decoy receptors:
5007:
4912:Stem cell factor
4853:Persephin (PSPN)
4791:Neurturin (NRTN)
4740:
4577:LEVI-04 (p75-Fc)
4574:Decoy receptors:
4188:
3617:
3216:
3210:
3078:
3071:
3064:
3055:
2983:
2976:
2969:
2960:
2587:
2519:
2302:
2287:
1899:
1890:
1868:
1861:
1854:
1845:
1751:Platelet-derived
1693:
1666:
1653:
1547:
1505:
1451:
1408:
1398:
1378:
1371:
1364:
1355:
1321:
1320:
1310:
1270:
1264:
1263:
1253:
1221:
1215:
1214:
1178:
1172:
1171:
1151:
1145:
1144:
1124:
1118:
1117:
1107:
1097:
1073:
1067:
1056:
971:aplastic anaemia
932:Uses in medicine
363:
360:
342:
341:
335:
132:
125:
121:
118:
112:
110:
69:
45:
37:
21:
6028:
6027:
6023:
6022:
6021:
6019:
6018:
6017:
5998:
5997:
5996:
5991:
5936:Midkine (NEGF2)
5814:
5597:
5496:
5265:
5203:ABT-110 (PG110)
4996:
4976:
4886:
4867:
4836:
4805:
4774:
4729:
4581:
4519:ABT-110 (PG110)
4420:
4357:
4319:
4177:
3991:
3972:
3912:
3909:(against FGF23)
3831:
3698:
3602:
3545:
3491:
3404:
3215:
3199:
3168:
3090:
3082:
3052:
3047:
3036:Intussusception
2992:
2987:
2957:
2952:
2918:
2897:
2855:
2845:
2803:
2776:
2696:
2678:
2576:
2504:
2473:
2436:
2374:
2346:
2297:
2295:
2293:
2276:
2182:
2161:
2145:
2048:
1881:
1872:
1842:
1837:
1816:
1778:
1741:
1687:
1682:
1656:
1647:
1640:
1605:
1583:EGF-like domain
1573:
1540:
1535:
1501:
1496:
1445:
1440:
1401:
1387:
1382:
1330:
1325:
1324:
1285:(6): CD011741.
1272:
1271:
1267:
1236:(6): H1029-38.
1223:
1222:
1218:
1180:
1179:
1175:
1153:
1152:
1148:
1141:
1126:
1125:
1121:
1075:
1074:
1070:
1059:"growth factor"
1057:
1053:
1048:
991:
978:transplantation
934:
906:
364:
358:
355:
339:
333:
331:List of classes
219:
163:steroid hormone
133:
122:
116:
113:
76:"Growth factor"
70:
68:
58:
46:
35:
28:
23:
22:
15:
12:
11:
5:
6026:
6024:
6016:
6015:
6010:
6008:Growth factors
6000:
5999:
5993:
5992:
5990:
5989:
5979:
5978:
5973:
5966:Thrombopoietin
5963:
5958:
5953:
5948:
5943:
5938:
5933:
5928:
5923:
5909:
5904:
5899:
5894:
5887:Erythropoietin
5884:
5846:
5841:
5831:
5829:Adrenomedullin
5822:
5820:
5816:
5815:
5813:
5812:
5803:
5802:
5797:
5792:
5787:
5782:
5773:
5772:
5767:
5762:
5757:
5752:
5747:
5742:
5737:
5732:
5727:
5722:
5717:
5712:
5707:
5702:
5697:
5692:
5687:
5682:
5677:
5672:
5663:
5662:
5653:
5652:
5630:
5625:
5620:
5611:
5609:
5603:
5602:
5599:
5598:
5596:
5595:
5590:
5585:
5580:
5575:
5570:
5565:
5560:
5555:
5550:
5545:
5540:
5535:
5526:
5525:
5520:
5515:
5506:
5504:
5498:
5497:
5495:
5494:
5489:
5484:
5479:
5474:
5469:
5464:
5459:
5454:
5449:
5444:
5439:
5434:
5425:
5424:
5415:
5414:
5409:
5404:
5395:
5394:
5389:
5384:
5379:
5374:
5369:
5364:
5359:
5354:
5349:
5344:
5339:
5334:
5329:
5324:
5319:
5314:
5309:
5304:
5299:
5294:
5292:4'-DMA-7,8-DHF
5289:
5284:
5275:
5273:
5267:
5266:
5264:
5263:
5254:
5253:
5241:
5240:
5235:
5230:
5225:
5220:
5215:
5210:
5205:
5186:
5185:
5179:
5174:
5169:
5164:
5159:
5154:
5149:
5144:
5139:
5134:
5129:
5124:
5119:
5114:
5109:
5100:
5099:
5090:
5089:
5084:
5079:
5074:
5065:
5064:
5059:
5054:
5052:Gambogic amide
5049:
5044:
5039:
5034:
5029:
5024:
5015:
5013:
5004:
4998:
4997:
4995:
4994:
4986:
4984:
4978:
4977:
4975:
4974:
4969:
4964:
4959:
4954:
4949:
4944:
4939:
4934:
4929:
4924:
4915:
4914:
4909:
4900:
4898:
4892:
4891:
4888:
4887:
4885:
4884:
4875:
4873:
4869:
4868:
4866:
4865:
4856:
4855:
4846:
4844:
4838:
4837:
4835:
4834:
4825:
4824:
4822:Artemin (ARTN)
4815:
4813:
4807:
4806:
4804:
4803:
4794:
4793:
4784:
4782:
4776:
4775:
4773:
4772:
4763:
4762:
4757:
4748:
4746:
4737:
4731:
4730:
4728:
4727:
4722:
4717:
4708:
4707:
4702:
4697:
4692:
4687:
4682:
4677:
4672:
4667:
4662:
4657:
4652:
4647:
4642:
4637:
4632:
4623:
4622:
4600:
4591:
4589:
4583:
4582:
4580:
4579:
4570:
4569:
4557:
4556:
4551:
4546:
4541:
4536:
4531:
4526:
4521:
4509:
4508:
4503:
4498:
4493:
4484:
4483:
4478:
4473:
4468:
4463:
4458:
4453:
4448:
4443:
4434:
4432:
4426:
4425:
4422:
4421:
4419:
4418:
4413:
4404:
4403:
4365:
4363:
4359:
4358:
4356:
4355:
4349:
4340:
4339:
4329:
4327:
4321:
4320:
4318:
4317:
4311:
4306:
4301:
4296:
4291:
4286:
4281:
4276:
4267:
4266:
4261:
4256:
4251:
4246:
4237:
4236:
4231:
4226:
4221:
4216:
4211:
4206:
4196:
4194:
4185:
4179:
4178:
4176:
4175:
4170:
4165:
4160:
4155:
4150:
4145:
4136:
4135:
4130:
4125:
4120:
4115:
4110:
4105:
4100:
4095:
4090:
4085:
4080:
4075:
4070:
4065:
4060:
4055:
4050:
4045:
4040:
4031:
4030:
4021:
4020:
4015:
4005:
4003:
3997:
3996:
3993:
3992:
3990:
3989:
3980:
3978:
3974:
3973:
3971:
3970:
3965:
3931:
3922:
3920:
3914:
3913:
3911:
3910:
3900:
3899:
3894:
3889:
3884:
3850:
3841:
3839:
3833:
3832:
3830:
3829:
3820:
3819:
3814:
3805:
3804:
3799:
3794:
3789:
3784:
3779:
3717:
3708:
3706:
3700:
3699:
3697:
3696:
3691:
3686:
3681:
3676:
3634:
3625:
3623:
3614:
3608:
3607:
3604:
3603:
3601:
3600:
3574:
3569:
3564:
3555:
3553:
3547:
3546:
3544:
3543:
3538:
3533:
3524:
3523:
3501:
3499:
3493:
3492:
3490:
3489:
3484:
3479:
3474:
3469:
3460:
3459:
3454:
3449:
3444:
3439:
3434:
3425:
3424:
3414:
3412:
3406:
3405:
3403:
3402:
3397:
3392:
3387:
3382:
3377:
3372:
3367:
3362:
3357:
3348:
3347:
3342:
3337:
3332:
3327:
3322:
3317:
3312:
3307:
3302:
3297:
3292:
3287:
3282:
3273:
3272:
3267:
3262:
3257:
3252:
3247:
3242:
3237:
3232:
3222:
3220:
3207:
3201:
3200:
3198:
3197:
3192:
3187:
3178:
3176:
3170:
3169:
3167:
3166:
3160:
3150:
3149:
3144:
3139:
3130:
3129:
3127:Angiopoietin 3
3124:
3122:Angiopoietin 2
3115:
3114:
3112:Angiopoietin 4
3109:
3107:Angiopoietin 1
3100:
3098:
3092:
3091:
3083:
3081:
3080:
3073:
3066:
3058:
3049:
3048:
3046:
3045:
3043:Vasculogenesis
3040:
3039:
3038:
3028:
3023:
3018:
3013:
3008:
3006:Maggot therapy
3003:
2997:
2994:
2993:
2988:
2986:
2985:
2978:
2971:
2963:
2954:
2953:
2951:
2950:
2949:
2948:
2947:
2946:
2941:
2936:
2931:
2926:
2916:
2912:
2911:
2910:
2905:
2895:
2886:
2880:
2879:
2878:
2877:
2872:
2859:
2857:
2851:
2850:
2847:
2846:
2844:
2843:
2838:
2833:
2832:
2831:
2826:
2815:
2813:
2809:
2808:
2805:
2804:
2802:
2801:
2786:
2784:
2778:
2777:
2775:
2774:
2769:
2764:
2759:
2754:
2749:
2744:
2739:
2734:
2729:
2724:
2714:
2712:
2710:Ig superfamily
2706:
2705:
2702:
2701:
2698:
2697:
2695:
2694:
2688:
2686:
2680:
2679:
2677:
2676:
2671:
2666:
2661:
2656:
2651:
2646:
2641:
2636:
2631:
2626:
2621:
2616:
2611:
2606:
2601:
2595:
2593:
2584:
2578:
2577:
2575:
2574:
2573:
2572:
2567:
2557:
2552:
2547:
2542:
2537:
2527:
2525:
2516:
2510:
2509:
2506:
2505:
2503:
2502:
2497:
2492:
2487:
2481:
2479:
2475:
2474:
2472:
2471:
2466:
2461:
2456:
2450:
2448:
2438:
2437:
2435:
2434:
2433:
2432:
2427:
2422:
2417:
2406:
2401:
2396:
2391:
2385:
2383:
2376:
2375:
2373:
2372:
2367:
2362:
2356:
2354:
2348:
2347:
2345:
2344:
2339:
2334:
2329:
2320:
2310:
2308:
2299:
2284:
2278:
2277:
2275:
2274:
2269:
2264:
2259:
2254:
2249:
2244:
2239:
2234:
2229:
2224:
2219:
2218:
2217:
2212:
2202:
2196:
2194:
2188:
2187:
2184:
2183:
2181:
2180:
2175:
2169:
2167:
2163:
2162:
2160:
2159:
2153:
2151:
2147:
2146:
2144:
2143:
2138:
2133:
2128:
2123:
2118:
2113:
2108:
2103:
2098:
2093:
2088:
2083:
2078:
2073:
2068:
2063:
2056:
2054:
2050:
2049:
2047:
2046:
2041:
2036:
2031:
2026:
2021:
2016:
2011:
2006:
2001:
1996:
1990:
1985:
1980:
1975:
1970:
1965:
1960:
1955:
1950:
1945:
1940:
1935:
1929:
1923:
1917:
1911:
1905:
1903:
1896:
1887:
1883:
1882:
1875:Cell signaling
1873:
1871:
1870:
1863:
1856:
1848:
1839:
1838:
1836:
1835:
1830:
1824:
1822:
1818:
1817:
1815:
1814:
1809:
1804:
1799:
1794:
1788:
1786:
1780:
1779:
1777:
1776:
1771:
1766:
1761:
1755:
1753:
1747:
1746:
1743:
1742:
1740:
1739:
1738:
1737:
1732:
1727:
1717:
1712:
1707:
1702:
1696:
1694:
1684:
1683:
1681:
1680:
1675:
1669:
1667:
1650:
1648:Relaxin family
1642:
1641:
1639:
1638:
1637:
1636:
1631:
1626:
1615:
1613:
1607:
1606:
1604:
1603:
1598:
1593:
1587:
1585:
1579:
1578:
1575:
1574:
1572:
1571:
1566:
1561:
1556:
1550:
1548:
1537:
1536:
1534:
1533:
1527:
1521:
1515:
1508:
1506:
1498:
1497:
1495:
1494:
1481:
1468:
1454:
1452:
1442:
1441:
1439:
1438:
1425:
1411:
1409:
1395:
1389:
1388:
1385:Growth factors
1383:
1381:
1380:
1373:
1366:
1358:
1352:
1351:
1346:
1341:
1334:Growth+Factors
1329:
1328:External links
1326:
1323:
1322:
1265:
1216:
1173:
1146:
1139:
1119:
1068:
1050:
1049:
1047:
1044:
1043:
1042:
1037:
1032:
1027:
1022:
1017:
1012:
1007:
1002:
997:
990:
987:
986:
985:
979:
973:
968:
963:
957:
952:
933:
930:
910:alpha granules
905:
902:
901:
900:
894:
888:
887:
886:
880:
869:
866:Thrombopoietin
863:
857:
851:
845:
839:
838:
837:
834:Neurotrophin-4
831:
828:Neurotrophin-3
825:
819:
808:
807:
806:
800:
794:
788:
777:
771:
765:
759:
753:
752:
751:
745:
739:
733:
727:
721:
715:
706:
705:
704:
698:
687:
682:
676:
670:
664:
663:
662:
657:
652:
647:
636:
630:
629:
628:
623:
618:
613:
608:
603:
598:
593:
588:
583:
578:
573:
568:
563:
558:
553:
548:
542:
537:
532:
527:
522:
517:
506:
503:Erythropoietin
500:
499:
498:
493:
488:
483:
478:
473:
468:
463:
453:
447:
446:
445:
439:
433:
422:
421:
420:
414:
408:
399:
393:
388:
382:
379:Adrenomedullin
372:evolutionarily
366:
365:
345:
343:
332:
329:
218:
215:
135:
134:
49:
47:
40:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
6025:
6014:
6013:Immune system
6011:
6009:
6006:
6005:
6003:
5987:
5984:
5981:
5980:
5977:
5974:
5971:
5967:
5964:
5962:
5959:
5957:
5954:
5952:
5949:
5947:
5944:
5942:
5939:
5937:
5934:
5932:
5929:
5927:
5924:
5921:
5917:
5913:
5910:
5908:
5905:
5903:
5900:
5898:
5895:
5892:
5888:
5885:
5882:
5878:
5874:
5870:
5866:
5862:
5858:
5854:
5850:
5847:
5845:
5842:
5839:
5835:
5832:
5830:
5827:
5824:
5823:
5821:
5817:
5811:
5808:
5805:
5804:
5801:
5798:
5796:
5793:
5791:
5788:
5786:
5783:
5781:
5778:
5775:
5774:
5771:
5768:
5766:
5763:
5761:
5758:
5756:
5753:
5751:
5748:
5746:
5743:
5741:
5738:
5736:
5733:
5731:
5728:
5726:
5723:
5721:
5718:
5716:
5713:
5711:
5708:
5706:
5703:
5701:
5698:
5696:
5693:
5691:
5688:
5686:
5683:
5681:
5678:
5676:
5673:
5671:
5668:
5665:
5664:
5661:
5660:Cyclotraxin B
5658:
5655:
5654:
5650:
5646:
5642:
5638:
5634:
5631:
5629:
5626:
5624:
5621:
5619:
5616:
5613:
5612:
5610:
5608:
5604:
5594:
5591:
5589:
5586:
5584:
5581:
5579:
5576:
5574:
5573:Larotrectinib
5571:
5569:
5566:
5564:
5561:
5559:
5556:
5554:
5551:
5549:
5546:
5544:
5541:
5539:
5536:
5534:
5531:
5528:
5527:
5524:
5521:
5519:
5516:
5514:
5511:
5508:
5507:
5505:
5503:
5499:
5493:
5490:
5488:
5485:
5483:
5480:
5478:
5475:
5473:
5472:Larotrectinib
5470:
5468:
5465:
5463:
5460:
5458:
5455:
5453:
5450:
5448:
5445:
5443:
5440:
5438:
5435:
5433:
5430:
5427:
5426:
5423:
5420:
5417:
5416:
5413:
5410:
5408:
5407:Cyclotraxin B
5405:
5403:
5400:
5397:
5396:
5393:
5390:
5388:
5385:
5383:
5380:
5378:
5375:
5373:
5370:
5368:
5365:
5363:
5360:
5358:
5355:
5353:
5350:
5348:
5345:
5343:
5340:
5338:
5335:
5333:
5330:
5328:
5325:
5323:
5320:
5318:
5317:Amitriptyline
5315:
5313:
5310:
5308:
5305:
5303:
5300:
5298:
5295:
5293:
5290:
5288:
5285:
5283:
5280:
5277:
5276:
5274:
5272:
5268:
5262:
5259:
5256:
5255:
5252:
5249:
5246:
5243:
5242:
5239:
5236:
5234:
5231:
5229:
5226:
5224:
5221:
5219:
5216:
5214:
5211:
5209:
5206:
5204:
5201:
5197:
5194:
5193:Against TrkA:
5191:
5188:
5187:
5183:
5180:
5178:
5175:
5173:
5170:
5168:
5165:
5163:
5160:
5158:
5155:
5153:
5150:
5148:
5147:Larotrectinib
5145:
5143:
5140:
5138:
5135:
5133:
5130:
5128:
5125:
5123:
5120:
5118:
5115:
5113:
5110:
5108:
5105:
5102:
5101:
5098:
5095:
5092:
5091:
5088:
5085:
5083:
5080:
5078:
5077:Dexamethasone
5075:
5073:
5070:
5067:
5066:
5063:
5060:
5058:
5055:
5053:
5050:
5048:
5045:
5043:
5040:
5038:
5035:
5033:
5030:
5028:
5025:
5023:
5022:Amitriptyline
5020:
5017:
5016:
5014:
5012:
5008:
5005:
5003:
4999:
4992:
4988:
4987:
4985:
4983:
4979:
4973:
4970:
4968:
4965:
4963:
4960:
4958:
4955:
4953:
4950:
4948:
4945:
4943:
4940:
4938:
4935:
4933:
4930:
4928:
4925:
4923:
4920:
4917:
4916:
4913:
4910:
4908:
4905:
4902:
4901:
4899:
4897:
4893:
4883:
4880:
4877:
4876:
4874:
4870:
4864:
4861:
4858:
4857:
4854:
4851:
4848:
4847:
4845:
4843:
4839:
4833:
4830:
4827:
4826:
4823:
4820:
4817:
4816:
4814:
4812:
4808:
4802:
4799:
4796:
4795:
4792:
4789:
4786:
4785:
4783:
4781:
4777:
4771:
4768:
4765:
4764:
4761:
4758:
4756:
4753:
4750:
4749:
4747:
4745:
4741:
4738:
4736:
4732:
4726:
4723:
4721:
4718:
4716:
4713:
4710:
4709:
4706:
4703:
4701:
4698:
4696:
4693:
4691:
4688:
4686:
4683:
4681:
4678:
4676:
4673:
4671:
4668:
4666:
4663:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4641:
4638:
4636:
4633:
4631:
4628:
4625:
4624:
4620:
4616:
4612:
4608:
4604:
4601:
4599:
4596:
4593:
4592:
4590:
4588:
4584:
4578:
4575:
4572:
4571:
4568:
4565:
4562:
4559:
4558:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4535:
4532:
4530:
4527:
4525:
4522:
4520:
4517:
4514:
4511:
4510:
4507:
4504:
4502:
4499:
4497:
4496:Dexamethasone
4494:
4492:
4489:
4486:
4485:
4482:
4479:
4477:
4474:
4472:
4469:
4467:
4464:
4462:
4459:
4457:
4454:
4452:
4449:
4447:
4444:
4442:
4439:
4436:
4435:
4433:
4431:
4427:
4417:
4414:
4412:
4409:
4406:
4405:
4401:
4397:
4393:
4389:
4385:
4381:
4377:
4373:
4370:
4367:
4366:
4364:
4360:
4353:
4350:
4348:
4345:
4342:
4341:
4338:
4334:
4331:
4330:
4328:
4326:
4322:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4295:
4292:
4290:
4287:
4285:
4282:
4280:
4277:
4275:
4272:
4269:
4268:
4265:
4262:
4260:
4257:
4255:
4252:
4250:
4247:
4245:
4242:
4239:
4238:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4205:
4204:des(1-3)IGF-1
4201:
4198:
4197:
4195:
4193:
4189:
4186:
4184:
4180:
4174:
4171:
4169:
4168:Telisotuzumab
4166:
4164:
4161:
4159:
4156:
4154:
4151:
4149:
4146:
4144:
4141:
4138:
4137:
4134:
4131:
4129:
4126:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4061:
4059:
4056:
4054:
4051:
4049:
4046:
4044:
4041:
4039:
4036:
4033:
4032:
4029:
4026:
4025:Potentiators:
4023:
4022:
4019:
4016:
4014:
4010:
4007:
4006:
4004:
4002:
3998:
3988:
3985:
3982:
3981:
3979:
3975:
3969:
3966:
3963:
3959:
3955:
3951:
3947:
3943:
3939:
3935:
3932:
3930:
3927:
3924:
3923:
3921:
3919:
3915:
3908:
3905:
3902:
3901:
3898:
3895:
3893:
3890:
3888:
3887:Selpercatinib
3885:
3882:
3878:
3874:
3870:
3866:
3862:
3858:
3854:
3851:
3849:
3846:
3843:
3842:
3840:
3838:
3834:
3828:
3825:
3822:
3821:
3818:
3815:
3813:
3810:
3807:
3806:
3803:
3800:
3798:
3795:
3793:
3792:Selpercatinib
3790:
3788:
3785:
3783:
3780:
3777:
3773:
3769:
3765:
3761:
3757:
3753:
3749:
3745:
3741:
3737:
3733:
3729:
3725:
3721:
3718:
3716:
3713:
3710:
3709:
3707:
3705:
3701:
3695:
3692:
3690:
3687:
3685:
3684:Selpercatinib
3682:
3680:
3677:
3674:
3670:
3666:
3662:
3658:
3654:
3650:
3646:
3642:
3638:
3635:
3633:
3630:
3627:
3626:
3624:
3622:
3618:
3615:
3613:
3609:
3598:
3594:
3590:
3586:
3582:
3578:
3575:
3573:
3570:
3568:
3565:
3563:
3560:
3557:
3556:
3554:
3552:
3548:
3542:
3539:
3537:
3534:
3532:
3529:
3526:
3525:
3521:
3517:
3513:
3509:
3506:
3503:
3502:
3500:
3498:
3494:
3488:
3485:
3483:
3480:
3478:
3475:
3473:
3470:
3468:
3465:
3462:
3461:
3458:
3455:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3433:
3430:
3427:
3426:
3423:
3419:
3416:
3415:
3413:
3411:
3407:
3401:
3398:
3396:
3393:
3391:
3388:
3386:
3383:
3381:
3378:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3360:Depatuxizumab
3358:
3356:
3353:
3350:
3349:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3326:
3323:
3321:
3318:
3316:
3313:
3311:
3308:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3288:
3286:
3283:
3281:
3278:
3275:
3274:
3271:
3268:
3266:
3263:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3236:
3233:
3231:
3227:
3224:
3223:
3221:
3219:
3211:
3208:
3206:
3202:
3196:
3193:
3191:
3188:
3186:
3183:
3180:
3179:
3177:
3175:
3171:
3164:
3161:
3158:
3155:
3152:
3151:
3148:
3145:
3143:
3140:
3138:
3135:
3132:
3131:
3128:
3125:
3123:
3120:
3117:
3116:
3113:
3110:
3108:
3105:
3102:
3101:
3099:
3097:
3093:
3089:
3086:
3079:
3074:
3072:
3067:
3065:
3060:
3059:
3056:
3044:
3041:
3037:
3034:
3033:
3032:
3029:
3027:
3024:
3022:
3019:
3017:
3016:Growth factor
3014:
3012:
3009:
3007:
3004:
3002:
2999:
2998:
2995:
2991:
2990:Wound healing
2984:
2979:
2977:
2972:
2970:
2965:
2964:
2961:
2945:
2942:
2940:
2937:
2935:
2932:
2930:
2927:
2925:
2922:
2921:
2920:
2913:
2909:
2906:
2904:
2901:
2900:
2899:
2892:
2891:
2890:
2887:
2885:
2882:
2881:
2876:
2873:
2871:
2868:
2867:
2866:
2865:
2861:
2860:
2858:
2852:
2842:
2839:
2837:
2834:
2830:
2827:
2825:
2822:
2821:
2820:
2819:Hematopoietic
2817:
2816:
2814:
2810:
2799:
2795:
2791:
2788:
2787:
2785:
2783:
2779:
2773:
2770:
2768:
2765:
2763:
2760:
2758:
2755:
2753:
2750:
2748:
2745:
2743:
2740:
2738:
2735:
2733:
2730:
2728:
2725:
2723:
2719:
2716:
2715:
2713:
2711:
2707:
2693:
2690:
2689:
2687:
2685:
2681:
2675:
2672:
2670:
2667:
2665:
2662:
2660:
2657:
2655:
2652:
2650:
2647:
2645:
2642:
2640:
2637:
2635:
2632:
2630:
2627:
2625:
2622:
2620:
2617:
2615:
2612:
2610:
2607:
2605:
2602:
2600:
2597:
2596:
2594:
2592:
2588:
2585:
2583:
2579:
2571:
2568:
2566:
2563:
2562:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2536:
2532:
2529:
2528:
2526:
2524:
2520:
2517:
2515:
2511:
2501:
2498:
2496:
2493:
2491:
2488:
2486:
2483:
2482:
2480:
2476:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2451:
2449:
2447:
2443:
2439:
2431:
2428:
2426:
2423:
2421:
2418:
2416:
2412:
2411:
2410:
2407:
2405:
2402:
2400:
2397:
2395:
2392:
2390:
2387:
2386:
2384:
2382:
2377:
2371:
2368:
2366:
2363:
2361:
2358:
2357:
2355:
2353:
2349:
2343:
2340:
2338:
2335:
2333:
2330:
2328:
2324:
2321:
2319:
2315:
2312:
2311:
2309:
2307:
2303:
2300:
2292:
2288:
2285:
2283:
2279:
2273:
2270:
2268:
2265:
2263:
2260:
2258:
2255:
2253:
2250:
2248:
2245:
2243:
2240:
2238:
2235:
2233:
2230:
2228:
2227:TNFSF5/CD40LG
2225:
2223:
2220:
2216:
2213:
2211:
2208:
2207:
2206:
2203:
2201:
2198:
2197:
2195:
2193:
2189:
2179:
2176:
2174:
2171:
2170:
2168:
2164:
2158:
2155:
2154:
2152:
2148:
2142:
2139:
2137:
2134:
2132:
2129:
2127:
2124:
2122:
2119:
2117:
2114:
2112:
2109:
2107:
2104:
2102:
2099:
2097:
2094:
2092:
2089:
2087:
2084:
2082:
2079:
2077:
2074:
2072:
2069:
2067:
2064:
2061:
2058:
2057:
2055:
2051:
2045:
2042:
2040:
2037:
2035:
2032:
2030:
2027:
2025:
2022:
2020:
2017:
2015:
2012:
2010:
2007:
2005:
2002:
2000:
1997:
1994:
1991:
1989:
1986:
1984:
1981:
1979:
1976:
1974:
1971:
1969:
1966:
1964:
1961:
1959:
1956:
1954:
1951:
1949:
1946:
1944:
1941:
1939:
1936:
1933:
1930:
1927:
1924:
1921:
1918:
1915:
1912:
1910:
1907:
1906:
1904:
1900:
1897:
1895:
1891:
1888:
1884:
1880:
1876:
1869:
1864:
1862:
1857:
1855:
1850:
1849:
1846:
1834:
1831:
1829:
1826:
1825:
1823:
1819:
1813:
1810:
1808:
1805:
1803:
1800:
1798:
1795:
1793:
1790:
1789:
1787:
1785:
1781:
1775:
1772:
1770:
1767:
1765:
1762:
1760:
1757:
1756:
1754:
1752:
1748:
1736:
1733:
1731:
1728:
1726:
1723:
1722:
1721:
1718:
1716:
1713:
1711:
1708:
1706:
1703:
1701:
1698:
1697:
1695:
1692:
1691:
1685:
1679:
1676:
1674:
1671:
1670:
1668:
1665:
1664:
1660:
1654:
1651:
1649:
1643:
1635:
1632:
1630:
1627:
1625:
1622:
1621:
1620:
1617:
1616:
1614:
1612:
1608:
1602:
1599:
1597:
1594:
1592:
1589:
1588:
1586:
1584:
1580:
1570:
1567:
1565:
1562:
1560:
1557:
1555:
1552:
1551:
1549:
1546:
1543:
1542:hormone-like:
1538:
1531:
1528:
1525:
1522:
1519:
1516:
1513:
1510:
1509:
1507:
1504:
1499:
1493:
1489:
1485:
1482:
1480:
1476:
1472:
1469:
1467:
1463:
1459:
1456:
1455:
1453:
1450:
1449:
1443:
1437:
1433:
1429:
1426:
1424:
1420:
1416:
1413:
1412:
1410:
1407:
1405:
1399:
1396:
1394:
1390:
1386:
1379:
1374:
1372:
1367:
1365:
1360:
1359:
1356:
1350:
1347:
1345:
1342:
1339:
1335:
1332:
1331:
1327:
1318:
1314:
1309:
1304:
1300:
1296:
1292:
1288:
1284:
1280:
1276:
1269:
1266:
1261:
1257:
1252:
1247:
1243:
1239:
1235:
1231:
1227:
1220:
1217:
1212:
1208:
1204:
1200:
1196:
1192:
1188:
1184:
1177:
1174:
1169:
1165:
1162:(4): 417–20.
1161:
1157:
1150:
1147:
1142:
1136:
1132:
1131:
1123:
1120:
1115:
1111:
1106:
1101:
1096:
1091:
1087:
1083:
1079:
1072:
1069:
1066:
1065:
1060:
1055:
1052:
1045:
1041:
1038:
1036:
1033:
1031:
1028:
1026:
1023:
1021:
1018:
1016:
1013:
1011:
1008:
1006:
1003:
1001:
998:
996:
993:
992:
988:
983:
980:
977:
974:
972:
969:
967:
964:
961:
958:
956:
953:
950:
947:
946:
945:
943:
939:
931:
929:
927:
923:
919:
915:
911:
903:
898:
895:
892:
889:
884:
881:
878:
875:
874:
873:
870:
867:
864:
861:
858:
855:
852:
849:
846:
843:
840:
835:
832:
829:
826:
823:
820:
817:
814:
813:
812:
811:Neurotrophins
809:
804:
801:
798:
795:
792:
789:
786:
783:
782:
781:
778:
775:
772:
769:
766:
763:
760:
757:
754:
749:
746:
743:
740:
737:
734:
731:
728:
725:
722:
719:
716:
713:
710:
709:
708:Interleukins
707:
702:
699:
696:
693:
692:
691:
688:
686:
683:
680:
677:
674:
671:
668:
665:
661:
658:
656:
653:
651:
648:
645:
642:
641:
640:
637:
634:
631:
627:
624:
622:
619:
617:
614:
612:
609:
607:
604:
602:
599:
597:
594:
592:
589:
587:
584:
582:
579:
577:
574:
572:
569:
567:
564:
562:
559:
557:
554:
552:
549:
546:
543:
541:
538:
536:
533:
531:
528:
526:
523:
521:
518:
516:
513:
512:
510:
507:
504:
501:
497:
494:
492:
489:
487:
484:
482:
479:
477:
474:
472:
469:
467:
464:
462:
459:
458:
457:
454:
451:
448:
443:
440:
437:
434:
431:
428:
427:
426:
423:
418:
417:Interleukin-6
415:
412:
409:
406:
403:
402:
400:
397:
394:
392:
389:
386:
383:
380:
377:
376:
375:
373:
362:
359:February 2011
353:
349:
346:This list is
344:
337:
336:
330:
328:
326:
322:
318:
313:
311:
310:
305:
301:
297:
293:
289:
285:
281:
277:
276:growth factor
272:
270:
266:
262:
258:
254:
250:
246:
242:
239:cells (e.g.,
238:
237:immune system
234:
233:hematopoietic
230:
228:
223:
222:Growth factor
216:
214:
212:
210:
206:
202:
198:
194:
189:
187:
183:
179:
175:
171:
166:
164:
160:
156:
152:
151:wound healing
148:
144:
143:growth factor
139:
131:
128:
120:
117:February 2014
109:
106:
102:
99:
95:
92:
88:
85:
81:
78: –
77:
73:
72:Find sources:
66:
62:
56:
55:
50:This article
48:
44:
39:
38:
33:
19:
5986:Cerebrolysin
5982:
5956:Pleiotrophin
5912:Interleukins
5825:
5806:
5776:
5695:Fruquintinib
5685:Cabozantinib
5666:
5656:
5614:
5578:Lestaurtinib
5529:
5509:
5477:Lestaurtinib
5428:
5418:
5399:Antagonists:
5398:
5332:Deoxygedunin
5287:3,7,8,2'-THF
5278:
5257:
5248:Against NGF:
5247:
5244:
5200:Against NGF:
5199:
5192:
5189:
5152:Lestaurtinib
5103:
5093:
5087:Testosterone
5069:Antagonists:
5068:
5018:
4918:
4903:
4878:
4859:
4849:
4828:
4818:
4797:
4787:
4766:
4751:
4711:
4626:
4594:
4573:
4564:Against NGF:
4563:
4560:
4516:Against NGF:
4515:
4512:
4506:Testosterone
4488:Antagonists:
4487:
4437:
4407:
4368:
4343:
4332:
4309:Teprotumumab
4270:
4240:
4199:
4148:Ficlatuzumab
4143:Emibetuzumab
4139:
4093:JNJ-38877605
4063:Cabozantinib
4034:
4024:
4013:Fosgonimeton
4008:
3983:
3925:
3903:
3844:
3827:Infigratinib
3823:
3808:
3711:
3628:
3562:Betacellulin
3558:
3541:Seribantumab
3527:
3504:
3463:
3428:
3422:Unknown/none
3421:
3417:
3351:
3276:
3235:Betacellulin
3230:Amphiregulin
3225:
3217:(ErbB1/HER1)
3181:
3153:
3133:
3119:Antagonists:
3118:
3103:
3096:Angiopoietin
3031:Angiogenesis
3015:
2914:
2893:
2862:
2854:By function/
2565:IL28/IFNL2+3
1688:
1657:
1646:Insulin/IGF/
1611:TGFβ pathway
1541:
1502:
1446:
1404:FGF receptor
1402:
1384:
1282:
1278:
1268:
1233:
1229:
1219:
1186:
1182:
1176:
1159:
1155:
1149:
1129:
1122:
1085:
1081:
1071:
1062:
1054:
995:Angiogenesis
982:angiogenesis
935:
907:
904:In platelets
803:Neuregulin 4
797:Neuregulin 3
791:Neuregulin 2
785:Neuregulin 1
385:Angiopoietin
369:
356:
314:
307:
283:
275:
273:
225:
221:
220:
213:
209:angiogenesis
197:osteogenesis
190:
167:
142:
140:
138:
123:
114:
104:
97:
90:
83:
71:
59:Please help
54:verification
51:
5946:Oncomodulin
5810:Aflibercept
5800:Ranibizumab
5795:Ramucirumab
5785:Bevacizumab
5777:Antibodies:
5735:Regorafenib
5675:Altiratinib
5588:ONO-5390556
5558:Entrectinib
5533:Altiratinib
5487:ONO-5390556
5457:Entrectinib
5432:Altiratinib
5218:Frunevetmab
5190:Antibodies:
5167:ONO-5390556
5132:Entrectinib
5107:Altiratinib
5062:Tavilermide
4957:Quizartinib
4896:SCF (c-Kit)
4720:Ramucirumab
4712:Antibodies:
4685:Quizartinib
4635:Avapritinib
4598:Becaplermin
4534:Frunevetmab
4513:Antibodies:
4416:Trofinetide
4347:Dusigitumab
4344:Antibodies:
4299:Robatumumab
4289:Figitumumab
4284:Dalotuzumab
4279:Cixutumumab
4271:Antibodies:
4163:Rilotumumab
4158:Onartuzumab
4153:Flanvotumab
4140:Antibodies:
4108:PF-04217903
4038:Altiratinib
4001:HGF (c-Met)
3904:Antibodies:
3809:Antibodies:
3531:Duligotumab
3528:Antibodies:
3442:Trastuzumab
3432:Ertumaxomab
3429:Antibodies:
3400:Zalutumumab
3395:Panitumumab
3390:Nimotuzumab
3385:Necitumumab
3375:Imgatuzumab
3352:Antibodies:
3335:Osimertinib
3300:Dacomitinib
3195:Dapiclermin
3154:Antibodies:
3137:Altiratinib
2782:IL17 family
2523:IL10 family
2442:IL12 family
2294:(grouped by
2282:Interleukin
2205:Lymphotoxin
976:bone marrow
955:neutropenia
938:hematologic
922:fibroblasts
918:macrophages
780:Neuregulins
296:cell growth
261:bone marrow
255:). For the
253:lymph nodes
241:lymphocytes
6002:Categories
5765:Vandetanib
5730:Rebastinib
5725:Pegaptanib
5715:Nintedanib
5705:Lenvatinib
5670:Agerafenib
5623:Ripretinib
5548:CH-7057288
5447:CH-7057288
5312:7,8,3'-THF
5307:7,8,2'-THF
5233:Ranevetmab
5223:Fulranumab
5177:Rebastinib
5122:CH-7057288
5037:Cenegermin
4922:Agerafenib
4882:Agerafenib
4863:Vandetanib
4832:Vandetanib
4801:Vandetanib
4770:Vandetanib
4715:Olaratumab
4690:Ripretinib
4670:Nintedanib
4655:Lenvatinib
4645:Crenolanib
4630:Agerafenib
4549:Ranevetmab
4539:Fulranumab
4456:Cenegermin
4430:LNGF (p75)
4352:Xentuzumab
4314:Xentuzumab
4259:NVP-AEW541
4254:NVP-ADW742
4249:Linsitinib
4244:BMS-754807
4229:Mecasermin
4128:Tivantinib
4118:PHA-665752
4113:PF-2341066
4083:Golvatinib
4073:Crizotinib
4068:Capmatinib
4058:BMS-777607
4053:Amuvatinib
3929:Ersofermin
3892:Sprifermin
3848:Ersofermin
3797:Sprifermin
3787:Repifermin
3782:Palifermin
3715:Ersofermin
3694:Velafermin
3679:Repifermin
3632:Ersofermin
3551:ErbB4/HER4
3536:Patritumab
3497:ErbB3/HER3
3477:Mubritinib
3437:Pertuzumab
3410:ErbB2/HER2
3340:Vandetanib
3295:Canertinib
3290:Brigatinib
3285:Agerafenib
3265:Nepidermin
3260:Murodermin
3250:Epiregulin
3205:EGF (ErbB)
3163:Nesvacumab
3157:Evinacumab
3147:Rebastinib
3088:modulators
2889:Lymphokine
2727:IL1B/IL1F2
2722:IL1A/IL1F1
2718:IL1 family
2582:Interferon
2570:IL29/IFNL1
1833:Hepatocyte
1393:Fibroblast
1046:References
348:incomplete
304:cell death
300:Fas ligand
87:newspapers
5790:Icrucumab
5770:WHI-P 154
5760:Tivozanib
5755:Toceranib
5750:Sunitinib
5745:Sorafenib
5740:Semaxanib
5720:Pazopanib
5710:Motesanib
5700:Lapatinib
5690:Cediranib
5628:Telbermin
5615:Agonists:
5563:GZ-389988
5543:CE-245677
5510:Agonists:
5462:GZ-389988
5442:CE-245677
5342:Diosmetin
5279:Agonists:
5245:Aptamers:
5238:Tanezumab
5213:Fasinumab
5157:Milciclib
5137:GZ-389988
5117:CE-245677
5019:Agonists:
4972:Toceranib
4967:Sunitinib
4962:Sorafenib
4952:Pazopanib
4947:Nilotinib
4942:Masitinib
4932:Dasatinib
4904:Agonists:
4850:Agonists:
4819:Agonists:
4788:Agonists:
4760:Liatermin
4752:Agonists:
4735:RET (GFL)
4725:Tovetumab
4705:Toceranib
4700:Sorafenib
4695:Sunitinib
4680:Radotinib
4675:Pazopanib
4665:Motesanib
4660:Masitinib
4595:Agonists:
4561:Aptamers:
4554:Tanezumab
4529:Fasinumab
4438:Agonists:
4294:Ganitumab
4214:IGF-1 LR3
4133:Volitinib
4088:INCB28060
4078:Foretinib
3984:Agonists:
3968:Trafermin
3926:Agonists:
3907:Burosumab
3897:Trafermin
3845:Agonists:
3812:Aprutumab
3802:Trafermin
3764:10 (KGF2)
3712:Agonists:
3689:Trafermin
3669:10 (KGF2)
3629:Agonists:
3559:Agonists:
3505:Agonists:
3487:Tucatinib
3482:Neratinib
3472:Lapatinib
3380:Matuzumab
3370:Futuximab
3355:Cetuximab
3345:WHI-P 154
3330:Neratinib
3325:Lapatinib
3315:Grandinin
3310:Gefitinib
3305:Erlotinib
3182:Agonists:
3142:CE-245677
3104:Agonists:
3026:Stem cell
2767:33/IL1F11
2732:1Ra/IL1F3
2379:IL6 like/
2096:CXCL8/IL8
1894:Chemokine
1886:By family
1879:cytokines
1299:1469-493X
966:leukemias
951:(PDGF-BB)
942:oncologic
914:platelets
912:in blood
774:Myostatin
655:Persephin
650:Neurturin
496:Ephrin B3
491:Ephrin B2
486:Ephrin B1
481:Ephrin A5
476:Ephrin A4
471:Ephrin A3
466:Ephrin A2
461:Ephrin A1
309:apoptosis
269:molecules
182:receptors
174:cytokines
170:signaling
5972:instead)
5961:Renalase
5922:instead)
5893:instead)
5840:instead)
5680:Axitinib
5649:D (FIGF)
5593:PLX-7486
5583:ONO-4474
5538:AZD-6918
5492:PLX-7486
5482:ONO-4474
5437:AZD-6918
5419:Ligands:
5337:Deprenyl
5297:7,3'-DHF
5228:MEDI-578
5208:ASP-6294
5172:PLX-7486
5162:ONO-4474
5112:AZD-6918
5072:ALE-0540
4993:instead.
4937:Imatinib
4927:Axitinib
4907:Ancestim
4872:Unsorted
4650:Imatinib
4640:Axitinib
4544:MEDI-578
4524:ASP-6294
4491:ALE-0540
4333:Agonists
4274:AVE-1642
4200:Agonists
4123:SU-11274
4009:Agonists
3987:FGF15/19
3977:Unsorted
3942:2 (bFGF)
3861:2 (bFGF)
3728:2 (bFGF)
3645:2 (bFGF)
3467:Afatinib
3418:Agonists
3320:Icotinib
3280:Afatinib
3226:Agonists
3001:Fibrosis
2884:Monokine
2413:+non IL
2298:subunit)
2296:receptor
2267:TNFSF13B
2215:TNFC/LTB
2210:TNFB/LTA
1545:FGF15/19
1406:ligands:
1317:28594443
1260:26232236
1114:26334535
1005:Cytokine
989:See also
854:Renalase
444:(GM-CSF)
284:cytokine
227:cytokine
178:hormones
5849:Ephrins
5553:DS-6051
5452:DS-6051
5357:LM22A-4
5347:DMAQ-B1
5302:7,8-DHF
5282:3,7-DHF
5251:RBM-004
5196:GBR-900
5127:DS-6051
5097:VM-902A
4567:RBM-004
4264:OSl-906
4224:Insulin
4103:MK-2461
4048:AMG-458
3185:Axokine
2772:18/IL1G
2514:Type II
2446:IL12RB1
2352:β chain
2306:γ chain
2262:TNFSF13
2257:TNFSF11
2252:TNFSF10
1934:/RANTES
1720:Relaxin
1659:Insulin
1308:6481523
1251:4747916
1211:1659742
1191:Bibcode
1183:Science
1168:7909429
1105:4558932
1020:Mitogen
893:(TNF-α)
885:(TGF-β)
879:(TGF-α)
776:(GDF-8)
703:(IGF-2)
697:(IGF-1)
685:Insulin
660:Artemin
456:Ephrins
438:(G-CSF)
432:(M-CSF)
159:protein
101:scholar
5819:Others
5513:BNN-20
5402:ANA-12
5327:BNN-20
5047:DHEA-S
5032:BNN-27
5027:BNN-20
4466:DHEA-S
4451:BNN-27
4446:BNN-20
4362:Others
3567:Epigen
3245:Epigen
2762:IL1F10
2659:IFNA21
2654:IFNA17
2649:IFNA16
2644:IFNA14
2639:IFNA13
2634:IFNA10
2291:Type I
2247:TNFSF9
2242:TNFSF8
2237:TNFSF7
2232:TNFSF6
2222:TNFSF4
2157:CX3CL1
2141:CXCL17
2136:CXCL16
2131:CXCL15
2126:CXCL14
2121:CXCL13
2116:CXCL12
2111:CXCL11
2106:CXCL10
1928:/MIP1β
1922:/MIP1α
1807:VEGF-D
1802:VEGF-C
1797:VEGF-B
1792:VEGF-A
1601:HB-EGF
1532:(FHF4)
1526:(FHF2)
1520:(FHF1)
1514:(FHF3)
1340:(MeSH)
1315:
1305:
1297:
1258:
1248:
1209:
1166:
1137:
1112:
1102:
1088:: 29.
924:, and
899:(VEGF)
862:(TCGF)
850:(PDGF)
836:(NT-4)
830:(NT-3)
818:(BDNF)
805:(NRG4)
799:(NRG3)
793:(NRG2)
787:(NRG1)
681:(HDGF)
669:(GDF9)
646:(GDNF)
511:(FGF)
419:(IL-6)
407:(CNTF)
398:(BMPs)
292:GM-CSF
274:While
265:tissue
251:, and
249:thymus
245:spleen
103:
96:
89:
82:
74:
5968:(see
5918:(see
5889:(see
5836:(see
5568:K252a
5467:K252a
5142:K252a
5082:FX007
4842:GFRα4
4811:GFRα3
4780:GFRα2
4744:GFRα1
4372:IGFBP
4325:IGF-2
4304:R1507
4192:IGF-1
4098:K252a
3918:FGFR4
3837:FGFR3
3704:FGFR2
3621:FGFR1
2824:KITLG
2812:Other
2798:IL17A
2757:IL1F9
2752:IL1F8
2747:IL1F7
2742:IL1F6
2737:IL1F5
2674:IFNW1
2664:IFNB1
2629:IFNA8
2624:IFNA7
2619:IFNA6
2614:IFNA5
2609:IFNA4
2604:IFNA2
2599:IFNA1
2478:Other
2381:gp130
2370:GMCSF
2150:CX3CL
2101:CXCL9
2091:CXCL7
2086:CXCL6
2081:CXCL5
2076:CXCL4
2071:CXCL3
2066:CXCL2
2060:CXCL1
2044:CCL28
2039:CCL27
2034:CCL26
2029:CCL25
2024:CCL24
2019:CCL23
2014:CCL22
2009:CCL21
2004:CCL20
1999:CCL19
1993:CCL18
1988:CCL17
1983:CCL16
1978:CCL15
1973:CCL14
1968:CCL13
1963:CCL12
1958:CCL11
1916:/MCP1
1828:Nerve
1821:Other
1774:PDGFD
1769:PDGFC
1764:PDGFB
1759:PDGFA
1715:INSL6
1710:INSL5
1705:INSL4
1700:INSL3
1634:TGFβ3
1629:TGFβ2
1624:TGFβ1
1569:FGF23
1564:FGF21
1559:FGF19
1554:FGF15
1530:FGF14
1524:FGF13
1518:FGF12
1512:FGF11
1492:FGF20
1488:FGF16
1479:FGF18
1475:FGF17
1466:FGF22
1462:FGF10
962:(MDS)
868:(TPO)
844:(PGF)
824:(NGF)
764:(MSF)
758:(KGF)
675:(HGF)
635:(FBS)
505:(EPO)
452:(EGF)
413:(LIF)
387:(Ang)
288:G-CSF
186:cells
161:or a
108:JSTOR
94:books
5970:here
5920:here
5891:here
5838:here
5633:VEGF
5607:VEGF
5523:NT-3
5518:DHEA
5502:TrkC
5422:DHEA
5392:TDP6
5372:NT-4
5367:NT-3
5352:HIOC
5322:BDNF
5271:TrkB
5042:DHEA
5011:TrkA
4991:here
4989:See
4982:TGFβ
4587:PDGF
4481:NT-4
4476:NT-3
4461:DHEA
4441:BDNF
3190:CNTF
3174:CNTF
3021:Scar
2944:IL13
2939:IL10
2908:TNFβ
2903:IFNγ
2875:TNFA
2856:cell
2836:SPP1
2794:IL25
2790:IL17
2692:IFNG
2669:IFNK
2555:IL26
2550:IL24
2545:IL20
2540:IL19
2535:IL22
2531:IL10
2500:IL34
2495:IL32
2490:IL16
2485:IL14
2469:IL35
2464:IL27
2459:IL23
2454:IL12
2430:CTF1
2425:CNTF
2409:IL31
2404:IL30
2399:IL27
2394:IL11
2342:IL21
2327:IL13
2318:IL15
2200:TNFA
2178:XCL2
2173:XCL1
2053:CXCL
1953:CCL9
1948:CCL8
1943:CCL7
1938:CCL6
1932:CCL5
1926:CCL4
1920:CCL3
1914:CCL2
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