85:
57:
1045:
Different drugs can be prescribed depending on the type of disease. Vitamins (K, P and C) are essential in case of obstruction to walls of blood vessels. Also, vitamin K is required for the production of blood clotting factors, hence the injection of vitamin K
1443:
1428:
578:. Gene therapy treatments may be a solution as they involve in the insertion of normal genes to replace defective genes causing for the genetic disorder. Gene therapy is a source of active research that hold promise for the future.
517:
There are autoimmune causes of coagulation disorders. They include acquired antibodies to coagulation factors, termed inhibitors of coagulation. The main inhibitor is directed against clotting factor VIII. Another example is
509:
may also cause coagulopathy. Furthermore, cystic fibrosis has been known to cause bleeding diathesis, especially in undiagnosed infants, due to malabsorption of fat soluble vitamins like vitamin K.
1508:
126:
being produced and leads to excessive bleeding. Several types of coagulopathy are distinguished, ranging from mild to lethal. Coagulopathy can be caused by thinning of the skin (
1004:
and have regular blood check ups. Have an early diagnostic test for any blood disorders or blood diseases including hemophilia, hemorrhage, and sickle-cell anemia.
130:), such that the skin is weakened and is bruised easily and frequently without any trauma or injury to the body. Also, coagulopathy can be contributed by impaired
1501:
1494:
1038:) to help restore them and to improve the immune defense of the patient after excessive blood loss. Blood transfusion also caused the transfer of
1625:
649:
470:
1227:
1800:
1783:
1178:
1219:
1143:
349:
1862:
1814:
1384:
1581:
1868:
1854:
908:
575:
1842:
1805:
1282:
929:
571:
567:
430:
217:
161:
1675:
1995:
1571:
1009:
605:
1012:
blood tests are useful to investigate the reason behind the excessive bleeding. The PT evaluates coagulation factors
1950:
1795:
832:
2066:
1637:
1618:
1070:
519:
1247:
eMedicine. Author: Pankaj Patel, MD. Coauthor(s): Mageda
Mikhail, MD, Assistant Professor. Updated: Dec 18, 2008
2036:
1779:
1608:
1458:
502:
1819:
1336:
1263:
445:
While there are several possible causes, they generally result in excessive bleeding and a lack of clotting.
2128:
2026:
498:
1940:
1915:
1873:
676:
563:
408:
389:
323:
300:
1935:
1925:
1743:
973:
539:
127:
1691:
1586:
1576:
1360:
622:
466:
177:
1930:
1920:
1716:
1596:
1447:
1361:"Hemorrhagic diathesis: causes, symptoms, diagnosis, treatment | Competently about health on iLive"
423:
84:
2056:
1738:
1175:
1696:
1670:
2123:
1945:
1721:
1630:
1469:
1318:
1223:
1215:
1149:
1139:
1023:
73:
273:
Following are some complications of coagulopathies, some of them caused by their treatments:
1771:
1711:
1706:
1566:
1308:
1131:
1104:
1005:
741:
600:
333:
172:
2051:
1885:
1591:
1182:
885:
454:
1726:
1108:
1244:
2076:
1788:
1731:
1613:
1313:
1296:
1135:
1047:
1035:
615:
399:
210:
167:
1452:
2117:
2086:
1908:
1903:
1898:
1655:
1486:
1122:
Amin C, Sharathkumar A, Griest A (2014-01-01). "Bleeding diathesis and hemophilias".
764:
610:
531:
462:
131:
312:, potentially with severe pain and even destruction of the joint and development of
2096:
1538:
1001:
115:
1026:
involves the transfer of plasma containing all the necessary coagulating factors (
1463:
1211:
17:
1893:
1701:
1533:
1522:
566:
are the major genetic disorders associated with coagulopathy. Rare examples are
486:
119:
1212:
Disorders of thrombosis and hemostasis: clinical and laboratory practice. Page
2081:
2046:
2021:
1665:
1647:
1474:
1437:
1337:"Prothrombin Time (PT) w/INR and Partial Thromboplastin Time (PTT) Blood Test"
1185:
The
International Patient Organisation for Primary Immunodeficiencies (IPOPI).
1027:
952:
699:
559:
295:
290:, e.g. deep-muscle bleeding, leading to swelling, numbness or pain of a limb.
253:
190:
107:
99:
78:
56:
1042:
that can work along with coagulating factors for blood clotting to commence.
2071:
2016:
1603:
494:
474:
313:
153:
1322:
1153:
1075:
Doctors Health Press - Daily Free Health
Articles and Natural Health Advice
1985:
1980:
1970:
1829:
1660:
1518:
1039:
1031:
881:
857:
626:
506:
482:
458:
123:
95:
65:
114:(a condition of irregular and slow blood clotting), in turn caused by a
2031:
1990:
1020:. The analysis of both tests thus helps to diagnose certain disorders.
720:
555:
490:
231:
186:
1420:
1975:
1432:
811:
535:
381:
1095:
Douglas H (April 1949). "Cushing' Syndrome and Thymic
Carcinoma".
592:
Laboratory findings in various platelet and coagulation disorders
478:
558:
coagulation factors that allow normal clotting. Various types of
551:
1490:
353:, from blood transfusions that are given as treatment.
27:
High tendency to bleed due to a blood clotting disorder
1071:"Bleeding Diathesis: Causes, Symptoms, and Treatments"
1410:
2006:
1963:
1884:
1828:
1770:
1763:
1756:
1684:
1646:
1559:
1552:
1414:
513:
Autoimmune causes of acquired coagulation disorders
72:
40:
35:
530:Bleeding diathesis may also be caused by impaired
122:). Therefore, this may result in the reduction of
1259:
1257:
1255:
1253:
1016:, while the PTT evaluates coagulation factors
1502:
8:
1283:Von Willebrand disease --> Complications
1240:
1238:
1236:
1767:
1760:
1556:
1509:
1495:
1487:
1411:
1278:
1276:
1274:
1272:
1050:) is recommended to boost blood clotting.
590:
538:), or by thinning of the skin, such as in
83:
55:
32:
1312:
1097:QJM: An International Journal of Medicine
1214:Rodger L. Bick. Edition 3, illustrated.
522:, an autoimmune, hypercoagulable state.
453:Acquired causes of coagulopathy include
275:
141:
1062:
164:, where they may resemble a few bruises
106:is an unusual susceptibility to bleed (
1207:
1205:
1203:
1201:
1199:
1197:
1195:
1193:
1191:
650:Disseminated intravascular coagulation
481:can cause this condition, for example
471:disseminated intravascular coagulation
1171:
1169:
1167:
1165:
1163:
7:
1109:10.1093/oxfordjournals.qjmed.a066529
1385:"Treatments for bleeding disorders"
1285:By Mayo Clinic staff. Feb. 7, 2009
1266:By Mayo Clinic staff. May 16, 2009
1136:10.1016/B978-0-7020-4087-0.00070-X
25:
1018:I, II, V, VIII, IX, X, XI and XII
350:Transfusion transmitted infection
1863:platelet storage pool deficiency
1815:Heparin-induced thrombocytopenia
1582:Activated protein C resistance
1124:Handbook of Clinical Neurology
477:venom from certain species of
368:to clotting factor treatment.
1:
526:Causes other than coagulation
1676:Trousseau sign of malignancy
1297:"The future of gene therapy"
134:or impaired clot formation.
1996:Nonthrombocytopenic purpura
1572:Antithrombin III deficiency
1010:partial thromboplastin time
606:Partial thromboplastin time
587:Comparing coagulation tests
554:that typically produce the
505:and dengue shock syndrome.
118:(a defect in the system of
2145:
1951:Congenital afibrinogenemia
1855:Glanzmann's thrombasthenia
909:Glanzmann's thrombasthenia
833:Congenital afibrinogenemia
637:Normal or mildly prolonged
576:Glanzmann's thrombasthenia
2067:Gastrointestinal bleeding
1869:Hermansky–Pudlak syndrome
1638:Antiphospholipid syndrome
1619:Essential thrombocythemia
1529:
786:Liver failure, end-stage
520:antiphospholipid syndrome
63:
54:
2037:Subconjunctival bleeding
1843:Bernard–Soulier syndrome
1806:Upshaw–Schulman syndrome
1780:Thrombocytopenic purpura
1609:Sticky platelet syndrome
1301:Biotechnology Healthcare
1264:Hemophilia Complications
1176:Wiskott–Aldrich Syndrome
930:Bernard–Soulier syndrome
572:Wiskott–Aldrich syndrome
568:Bernard–Soulier syndrome
503:dengue hemorrhagic fever
499:Viral hemorrhagic fevers
431:Wiskott–Aldrich syndrome
260:Wiskott–Aldrich syndrome
239:Wiskott–Aldrich syndrome
218:Wiskott–Aldrich syndrome
162:Wiskott–Aldrich syndrome
2027:Intracranial hemorrhage
946:Decreased or unaffected
685:Prolonged or unaffected
220:, especially in infancy
1941:Factor XIII deficiency
1921:Hypoprothrombinemia/II
1916:von Willebrand disease
1874:Gray platelet syndrome
1295:McCain J (June 2005).
884:deficiency as seen in
677:Von Willebrand disease
564:von Willebrand disease
409:Von Willebrand disease
390:Von Willebrand disease
324:Von Willebrand disease
301:Von Willebrand disease
45:Haemorrhagic diathesis
1936:Factor XII deficiency
1926:Factor VII deficiency
1744:Renal vein thrombosis
953:Factor XII deficiency
49:Hemorrhagic diathesis
1692:Deep vein thrombosis
1587:Protein S deficiency
1577:Protein C deficiency
1245:Vitamin K Deficiency
623:Vitamin K deficiency
473:. Additionally, the
467:vitamin K deficiency
416:Vitamin K deficiency
403:(bleeding to death)
288:Soft tissue bleeding
203:Vitamin K deficiency
178:Vitamin K deficiency
1931:Factor X deficiency
1820:May–Hegglin anomaly
1597:Prothrombin G20210A
1014:I, II, V, VII and X
593:
424:Cerebral hemorrhage
68:wound in the finger
2057:Pulmonary hematoma
1964:Signs and symptoms
1739:Pulmonary embolism
1544:Bleeding diathesis
1181:2010-12-21 at the
591:
540:Cushing's syndrome
138:Signs and symptoms
128:Cushing's syndrome
104:bleeding diathesis
36:Bleeding diathesis
2111:
2110:
2107:
2106:
1959:
1958:
1946:Dysfibrinogenemia
1830:Platelet function
1752:
1751:
1631:Purpura fulminans
1484:
1483:
1228:978-0-397-51690-2
1024:Blood transfusion
993:
992:
550:Some people lack
438:
437:
366:Adverse reactions
266:
265:
112:hypocoagulability
92:
91:
30:Medical condition
18:Hypocoagulability
16:(Redirected from
2136:
1772:Thrombocytopenia
1768:
1761:
1717:Lowenberg's sign
1567:Clotting factors
1557:
1511:
1504:
1497:
1488:
1412:
1400:
1399:
1397:
1396:
1381:
1375:
1374:
1372:
1371:
1357:
1351:
1350:
1348:
1347:
1333:
1327:
1326:
1316:
1292:
1286:
1280:
1267:
1261:
1248:
1242:
1231:
1209:
1186:
1173:
1158:
1157:
1119:
1113:
1112:
1092:
1086:
1085:
1083:
1082:
1067:
1006:Prothrombin time
974:C1INH deficiency
742:Thrombocytopenia
601:Prothrombin time
594:
334:Retinal bleeding
276:
245:Chronic leukemia
200:Chronic leukemia
173:Chronic leukemia
142:
110:) mostly due to
88:
87:
59:
33:
21:
2144:
2143:
2139:
2138:
2137:
2135:
2134:
2133:
2114:
2113:
2112:
2103:
2052:Hemopericardium
2002:
1955:
1886:Clotting factor
1880:
1824:
1748:
1697:Bancroft's sign
1680:
1671:Virchow's triad
1642:
1592:Factor V Leiden
1548:
1525:
1515:
1485:
1480:
1479:
1423:
1409:
1404:
1403:
1394:
1392:
1383:
1382:
1378:
1369:
1367:
1359:
1358:
1354:
1345:
1343:
1335:
1334:
1330:
1294:
1293:
1289:
1281:
1270:
1262:
1251:
1243:
1234:
1210:
1189:
1183:Wayback Machine
1174:
1161:
1146:
1121:
1120:
1116:
1094:
1093:
1089:
1080:
1078:
1069:
1068:
1064:
1059:
1053:
998:
886:amyloid purpura
589:
584:
548:
528:
515:
455:anticoagulation
451:
443:
271:
140:
82:
31:
28:
23:
22:
15:
12:
11:
5:
2142:
2140:
2132:
2131:
2129:Coagulopathies
2126:
2116:
2115:
2109:
2108:
2105:
2104:
2102:
2101:
2100:
2099:
2091:
2090:
2089:
2084:
2079:
2077:Hemoperitoneum
2074:
2069:
2061:
2060:
2059:
2054:
2049:
2041:
2040:
2039:
2034:
2029:
2024:
2019:
2010:
2008:
2004:
2003:
2001:
2000:
1999:
1998:
1988:
1983:
1978:
1973:
1967:
1965:
1961:
1960:
1957:
1956:
1954:
1953:
1948:
1943:
1938:
1933:
1928:
1923:
1918:
1913:
1912:
1911:
1906:
1901:
1890:
1888:
1882:
1881:
1879:
1878:
1877:
1876:
1871:
1859:
1858:
1857:
1847:
1846:
1845:
1834:
1832:
1826:
1825:
1823:
1822:
1817:
1811:
1810:
1809:
1808:
1803:
1793:
1792:
1791:
1789:Evans syndrome
1776:
1774:
1765:
1758:
1754:
1753:
1750:
1749:
1747:
1746:
1741:
1736:
1735:
1734:
1729:
1724:
1722:Peabody's sign
1719:
1714:
1709:
1704:
1699:
1688:
1686:
1682:
1681:
1679:
1678:
1673:
1668:
1663:
1658:
1652:
1650:
1644:
1643:
1641:
1640:
1635:
1634:
1633:
1623:
1622:
1621:
1616:
1614:Thrombocytosis
1611:
1601:
1600:
1599:
1594:
1589:
1584:
1579:
1574:
1563:
1561:
1554:
1550:
1549:
1547:
1546:
1541:
1536:
1530:
1527:
1526:
1516:
1514:
1513:
1506:
1499:
1491:
1482:
1481:
1478:
1477:
1466:
1455:
1440:
1424:
1419:
1418:
1416:
1415:Classification
1408:
1407:External links
1405:
1402:
1401:
1376:
1352:
1328:
1287:
1268:
1249:
1232:
1187:
1159:
1144:
1114:
1103:(2): 133–147.
1087:
1061:
1060:
1058:
1055:
1048:phytomenadione
1036:thromboplastin
997:
994:
991:
990:
987:
984:
979:
976:
970:
969:
966:
963:
958:
955:
949:
948:
943:
938:
935:
932:
926:
925:
922:
917:
914:
911:
905:
904:
901:
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878:
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866:
861:
854:
853:
850:
845:
840:
835:
829:
828:
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808:
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802:
797:
792:
787:
783:
782:
779:
776:
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755:
750:
747:
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738:
737:
734:
729:
726:
723:
717:
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710:
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696:
695:
692:
687:
682:
679:
673:
672:
667:
662:
657:
652:
646:
645:
642:
639:
634:
629:
619:
618:
616:Platelet count
613:
608:
603:
598:
588:
585:
583:
580:
547:
544:
527:
524:
514:
511:
450:
447:
442:
439:
436:
435:
434:
433:
426:
420:
419:
418:
417:
414:
413:Acute leukemia
411:
404:
400:Exsanguination
395:
394:
393:
392:
385:
377:
376:
375:
374:
369:
362:
361:
360:
359:
354:
345:
344:
343:
342:
341:Acute leukemia
337:
329:
328:
327:
326:
321:
316:
306:
305:
304:
303:
298:
291:
284:
283:
280:
270:
267:
264:
263:
262:
261:
256:
249:
248:
247:
246:
243:
242:Acute leukemia
240:
235:
227:
226:
225:
224:
223:Acute leukemia
221:
213:
211:Blood in stool
207:
206:
205:
204:
201:
198:
197:Acute leukemia
193:
183:
182:
181:
180:
175:
170:
168:Acute leukemia
165:
157:
150:
149:
146:
139:
136:
90:
89:
76:
70:
69:
61:
60:
52:
51:
42:
38:
37:
29:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2141:
2130:
2127:
2125:
2122:
2121:
2119:
2098:
2095:
2094:
2092:
2088:
2087:Hematosalpinx
2085:
2083:
2080:
2078:
2075:
2073:
2070:
2068:
2065:
2064:
2062:
2058:
2055:
2053:
2050:
2048:
2045:
2044:
2042:
2038:
2035:
2033:
2030:
2028:
2025:
2023:
2020:
2018:
2015:
2014:
2012:
2011:
2009:
2005:
1997:
1994:
1993:
1992:
1989:
1987:
1984:
1982:
1979:
1977:
1974:
1972:
1969:
1968:
1966:
1962:
1952:
1949:
1947:
1944:
1942:
1939:
1937:
1934:
1932:
1929:
1927:
1924:
1922:
1919:
1917:
1914:
1910:
1907:
1905:
1902:
1900:
1897:
1896:
1895:
1892:
1891:
1889:
1887:
1883:
1875:
1872:
1870:
1867:
1866:
1865:
1864:
1860:
1856:
1853:
1852:
1851:
1848:
1844:
1841:
1840:
1839:
1836:
1835:
1833:
1831:
1827:
1821:
1818:
1816:
1813:
1812:
1807:
1804:
1802:
1799:
1798:
1797:
1794:
1790:
1787:
1786:
1785:
1781:
1778:
1777:
1775:
1773:
1769:
1766:
1762:
1759:
1755:
1745:
1742:
1740:
1737:
1733:
1730:
1728:
1725:
1723:
1720:
1718:
1715:
1713:
1712:Louvel's sign
1710:
1708:
1707:Lisker's sign
1705:
1703:
1700:
1698:
1695:
1694:
1693:
1690:
1689:
1687:
1683:
1677:
1674:
1672:
1669:
1667:
1664:
1662:
1659:
1657:
1656:Thrombophilia
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1653:
1651:
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1636:
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1627:
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1620:
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1612:
1610:
1607:
1606:
1605:
1602:
1598:
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1593:
1590:
1588:
1585:
1583:
1580:
1578:
1575:
1573:
1570:
1569:
1568:
1565:
1564:
1562:
1558:
1555:
1551:
1545:
1542:
1540:
1537:
1535:
1532:
1531:
1528:
1524:
1520:
1517:Disorders of
1512:
1507:
1505:
1500:
1498:
1493:
1492:
1489:
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1460:
1456:
1454:
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1449:
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1434:
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1422:
1417:
1413:
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1380:
1377:
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1338:
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1324:
1320:
1315:
1310:
1306:
1302:
1298:
1291:
1288:
1284:
1279:
1277:
1275:
1273:
1269:
1265:
1260:
1258:
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1254:
1250:
1246:
1241:
1239:
1237:
1233:
1229:
1225:
1221:
1220:0-397-51690-8
1217:
1213:
1208:
1206:
1204:
1202:
1200:
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2097:Hemarthrosis
1861:
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1727:Pratt's sign
1543:
1539:coagulopathy
1468:
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1393:. Retrieved
1391:. 2015-11-03
1388:
1379:
1368:. Retrieved
1364:
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1344:. Retrieved
1340:
1331:
1307:(3): 52–60.
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1079:. Retrieved
1077:. 2017-06-23
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1002:hematologist
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487:rattlesnakes
452:
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310:Joint damage
309:
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279:Complication
272:
156:(red spots)
116:coagulopathy
111:
103:
93:
48:
44:
1850:aggregation
1732:Rose's sign
1702:Homans sign
1534:Coagulation
1365:iliveok.com
1341:Walk-In Lab
1230:. 446 pages
1130:: 1045–59.
1032:prothrombin
989:Unaffected
986:Unaffected
978:Unaffected
968:Unaffected
965:Unaffected
957:Unaffected
937:Unaffected
934:Unaffected
924:Unaffected
916:Unaffected
913:Unaffected
903:Unaffected
900:Unaffected
876:Unaffected
873:Unaffected
860:deficiency
852:Unaffected
827:Unaffected
819:Unaffected
816:Unaffected
781:Unaffected
778:Unaffected
775:Unaffected
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728:Unaffected
725:Unaffected
715:Unaffected
712:Unaffected
704:Unaffected
694:Unaffected
681:Unaffected
644:Unaffected
641:Unaffected
254:nose bleeds
120:coagulation
41:Other names
2118:Categories
2082:Hematocele
2047:Hemothorax
2022:Hemoptysis
1894:Hemophilia
1666:Thrombosis
1470:DiseasesDB
1395:2018-09-17
1370:2018-09-17
1346:2018-09-17
1081:2018-09-17
1057:References
1028:fibrinogen
1000:Consult a
996:Treatments
700:Hemophilia
597:Condition
560:hemophilia
489:and other
373:Hemophilia
358:Hemophilia
320:Hemophilia
296:Hemophilia
282:Disorders
252:Prolonged
191:ecchymoses
148:Disorders
108:hemorrhage
100:hematology
79:Hematology
2072:Hemobilia
2017:Epistaxis
1604:Platelets
1389:Netdoctor
1040:platelets
982:Shortened
961:Prolonged
941:Prolonged
920:Prolonged
896:Prolonged
891:Prolonged
869:Prolonged
864:Prolonged
848:Prolonged
843:Prolonged
838:Prolonged
823:Prolonged
805:Decreased
800:Prolonged
795:Prolonged
790:Prolonged
771:Prolonged
758:Decreased
753:Prolonged
732:Prolonged
708:Prolonged
690:Prolonged
670:Decreased
665:Prolonged
660:Prolonged
655:Prolonged
632:Prolonged
582:Diagnosis
475:hemotoxic
314:arthritis
230:Bleeding
154:Petechiae
124:platelets
74:Specialty
2124:Bleeding
2063:abdomen
1986:Petechia
1981:Hematoma
1971:Bleeding
1838:adhesion
1764:By cause
1757:Bleeding
1661:Thrombus
1560:By cause
1553:Clotting
1523:clotting
1519:bleeding
1323:23393464
1179:Archived
1154:24365370
882:Factor X
858:Factor V
767:, early
627:warfarin
507:Leukemia
501:include
483:Bothrops
459:warfarin
449:Acquired
96:medicine
66:bleeding
2032:Hyphema
2007:By site
1991:Purpura
1685:By site
1464:D006474
1314:3564347
721:Aspirin
556:protein
546:Genetic
534:(as in
491:species
234:(gums)
232:gingiva
187:Purpura
145:Symptom
2093:joint
2043:torso
1976:Bruise
1899:A/VIII
1321:
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812:Uremia
536:scurvy
479:snakes
441:Causes
382:Anemia
81:
2013:head
1648:Clots
1453:287.9
1438:D69.9
552:genes
495:viper
457:with
1909:C/XI
1904:B/IX
1521:and
1475:1442
1459:MeSH
1448:9-CM
1319:PMID
1224:ISBN
1216:ISBN
1150:PMID
1140:ISBN
1008:and
574:and
562:and
469:and
189:and
1801:TTP
1784:ITP
1626:DIC
1444:ICD
1429:ICD
1309:PMC
1132:doi
1128:120
1105:doi
625:or
493:of
102:),
94:In
2120::
1796:TM
1782::
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1433:10
1387:.
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1271:^
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