57:
Research & Development Center (LRDC) at
University of Pittsburgh launched the 2009 Pittsburgh Brain Competition to invite the best research team to work on this problem. A prize of $ 10,000 was offered to the team that could track optic radiations, and teams from 168 countries took part in the competition. A winning team from Taiwan revealed Meyer's loop, which no other team had successfully tracked. The key of the method was multiple observations of water molecules and improved algorithms to better capture how axons connects brain regions. The technique was further developed as HDFT between the University of Pittsburgh and Carnegie Mellon University.
17:
73:(TBI) to identify which brain connections have been broken and which are still intact. HDFT allows neurosurgeons to localize fiber breaks caused by traumatic brain injuries to provide better diagnoses and prognoses. It could also provide an objective way of identifying brain injury, predicting outcome and planning rehabilitation. HDFT can also be used to determine the optimal surgical approach for difficult-to-reach tumors and vascular malformations.
1640:
541:
Shin, Samuel S.; Verstynen, Timothy; Pathak, Sudhir; Jarbo, Kevin; Hricik, Allison J.; Maserati, Megan; Beers, Sue R.; Puccio, Ava M.; Boada, Fernando E. (May 2012). "High-definition fiber tracking for assessment of neurological deficit in a case of traumatic brain injury: finding, visualizing, and
56:
Traditional DTI uses six diffusivity characteristics to model how water molecules diffuse in brain tissues and makes axonal fiber tracking possible. However, DTI had a major limitation in resolving axons from different tracts intersected and crossed en route to their target. In 2009, Learning
43:
connections. HDFT is based on data acquired from diffusion spectrum imaging and processed by generalized q-sampling imaging. The technique makes it possible to virtually dissect 40 major fiber tracts in the brain. The HDFT scan is consistent with brain anatomy unlike diffusion tensor imaging
113:
Fernandez-Miranda, Juan C.; Pathak, Sudhir; Engh, Johnathan; Jarbo, Kevin; Verstynen, Timothy; Yeh, Fang-Cheng; Wang, Yibao; Mintz, Arlan; Boada, Fernando (August 2012). "High-definition fiber tractography of the human brain: neuroanatomical validation and neurosurgical applications".
60:
HDFT is currently used by UPMC neurosurgery department to provide neurosurgical planning, neuro-structural damage assessment, intraoperative navigation, and evaluation of changes and responses to rehabilitation therapy after brain surgery.
157:
Wedeen, V. J.; Wang, R. P.; Schmahmann, J. D.; Benner, T.; Tseng, W. Y. I.; Dai, G.; Pandya, D. N.; Hagmann, P.; D'Arceuil, H. (2008-07-15). "Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers".
636:"Longitudinal evaluation of corticospinal tract in patients with resected brainstem cavernous malformations using high-definition fiber tractography and diffusion connectometry analysis: preliminary experience"
696:
thejns.org: High-definition fiber tracking for assessment of neurological deficit in a case of traumatic brain injury: finding, visualizing, and interpreting small sites of damage Case report
634:
Faraji, Amir H.; Abhinav, Kumar; Jarbo, Kevin; Yeh, Fang-Cheng; Shin, Samuel S.; Pathak, Sudhir; Hirsch, Barry E.; Schneider, Walter; Fernandez-Miranda, Juan C. (November 2015).
383:
1314:
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scanners is processed through computer algorithms to reveal the detailed wiring of the brain and to pinpoint fiber tracts. Each tract contains millions of
1468:
472:
Shin, Samuel S.; Pathak, Sudhir; Presson, Nora; Bird, William; Wagener, Lauren; Schneider, Walter; Okonkwo, David O.; Fernandez-Miranda, Juan C. (2014).
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upmc.com: New High
Definition Fiber Tracking Reveals Damage Caused by Traumatic Brain Injury, Pitt Team Reports
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Yeh, Fang-Cheng; Wedeen, Van Jay; Tseng, Wen-Yih Isaac (September 2010). "Generalized q-sampling imaging".
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337:"High Definition Fiber Tracking ' the nerve blog | Blog Archive | Boston University"
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Detection of white matter injury in concussion using high-definition fiber tractography
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1084:
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32:
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Alexander, Andrew L.; Lee, Jee Eun; Lazar, Mariana; Field, Aaron S. (July 2007).
127:
48:). Thus, the use of HDFT is essential in pinpointing damaged neural connections.
1509:
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pitt.edu: Featured in this “60 Minutes” feature: Apps for Autism
722:
364:
401:"Seeing the Brain's Broken Cables | DiscoverMagazine.com"
253:"Diffusion MRI Reconstruction in DSI Studio - DSI Studio"
707:
611:"High Definition Fiber Tracking | UPMC | Pittsburgh, PA"
449:"High Definition Fiber Tracking | UPMC | Pittsburgh, PA"
91:(fMRI), measures blood flow to infer neural activity
20:
High-definition fiber tracking of arcuate fasciculus
1613:
1585:
1541:
1490:
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1457:
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85:(DTI), uses the magnetic properties of water
382:: CS1 maint: numeric names: authors list (
1464:
1346:
1336:
932:
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767:
741:
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719:
651:
312:
1577:Orthogonal polarization spectral imaging
708:hdft.info: HDFT for Connection Disorders
15:
281:"Diffusion Tensor Imaging of the Brain"
100:
523:
513:
375:
542:interpreting small sites of damage".
89:Functional magnetic resonance imaging
7:
395:
393:
274:
272:
211:IEEE Transactions on Medical Imaging
108:
106:
104:
586:"University Times ' Research Notes"
1384:Sestamibi parathyroid scintigraphy
14:
1639:
1638:
476:. Vol. 28. pp. 86–93.
172:10.1016/j.neuroimage.2008.03.036
1141:Cholangiopancreatography (MRCP)
1389:Radioactive iodine uptake test
25:High definition fiber tracking
1:
1369:Radionuclide ventriculography
843:Lower gastrointestinal series
835:Upper gastrointestinal series
691:pitt.edu: Concept | HDFT
453:UPMC | Life Changing Medicine
1560:Optical coherence tomography
1482:Myocardial perfusion imaging
1070:Dental panoramic radiography
128:10.1227/NEU.0b013e3182592faa
1686:
1670:Magnetic resonance imaging
1364:Ventilation/perfusion scan
839:Small-bowel follow-through
297:10.1016/j.nurt.2007.05.011
35:technique where data from
1634:
1605:Dynamic angiothermography
1349:
1273:Abdominal ultrasonography
779:
653:10.3171/2014.12.JNS142169
69:HDFT has been applied to
1595:Non-contact thermography
1374:Radionuclide angiography
1226:Doppler echocardiography
590:University of Pittsburgh
556:10.3171/2012.1.JNS111282
429:dsi-studio.labsolver.org
361:PBAIC2009 (2009-02-05),
257:dsi-studio.labsolver.org
223:10.1109/TMI.2010.2045126
1379:Radioisotope renography
640:Journal of Neurosurgery
544:Journal of Neurosurgery
1414:Gastric emptying study
686:Fiber Tractography Lab
71:traumatic brain injury
21:
1075:X-ray motion analysis
958:X-ray microtomography
877:Hysterosalpingography
784:Pneumoencephalography
19:
1600:Contact thermography
1310:Emergency ultrasound
1248:Transcranial Doppler
999:Abdominal and pelvis
1567:Confocal microscopy
1445:Indium-111 WBC scan
1268:Echoencephalography
1004:Virtual colonoscopy
1555:Optical tomography
1404:Dacryoscintigraphy
1399:Immunoscintigraphy
1038:Whole body imaging
789:Dental radiography
22:
1652:
1651:
1614:Target conditions
1537:
1536:
1533:
1532:
1453:
1452:
1394:Bone scintigraphy
1359:Scintimammography
1354:Cholescintigraphy
1199:contrast-enhanced
1093:
1092:
1053:
1052:
1043:Full-body CT scan
943:General operation
922:
921:
892:Angiocardiography
491:978-3-318-02648-1
482:10.1159/000358767
405:Discover Magazine
341:Boston University
285:Neurotherapeutics
1677:
1642:
1641:
1465:
1347:
1337:
1221:Echocardiography
1080:Hounsfield scale
933:
852:Cholecystography
777:
768:
743:
736:
729:
720:
674:
673:
655:
646:(5): 1133–1144.
631:
625:
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607:
601:
600:
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597:
582:
576:
575:
550:(5): 1062–1069.
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1515:PET mammography
1486:
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1435:Gallium-67 scan
1430:Octreotide scan
1418:
1326:
1177:
1089:
1049:
972:
953:High-resolution
918:
882:Skeletal survey
848:Cholangiography
761:
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750:Medical imaging
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1572:Endomicroscopy
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914:Orbital x-ray
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809:Bronchography
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1621:Acute stroke
1587:Thermography
1342:scintigraphy
1332:Radionuclide
1320:pre-hospital
1166:Tractography
1085:Radiodensity
987:calcium scan
948:Quantitative
715:(2011-10-23)
704:(2012-03-02)
698:(2012-04-30)
643:
639:
629:
618:. Retrieved
615:www.upmc.com
614:
605:
594:. Retrieved
592:. 2012-03-22
580:
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543:
536:
473:
467:
456:. Retrieved
452:
443:
432:. Retrieved
428:
425:"DSI Studio"
419:
408:. Retrieved
404:
368:, retrieved
363:
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345:. Retrieved
343:. 2012-10-10
331:
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260:. Retrieved
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119:
116:Neurosurgery
115:
68:
65:Applications
59:
55:
33:tractography
28:
24:
23:
1510:Cardiac PET
1283:renal tract
1258:Gynecologic
1190:Techniques
1161:restriction
1136:Angiography
1119:Neurography
1065:Fluoroscopy
1011:Angiography
992:angiography
936:Techniques:
897:Aortography
887:Angiography
867:Cystography
857:Mammography
799:Myelography
794:Sialography
763:radiography
1665:Inventions
1659:Categories
1423:Full body:
1209:endoscopic
1183:Ultrasound
1112:functional
909:Lymphogram
904:Venography
872:Arthrogram
620:2018-01-31
596:2013-11-10
458:2019-04-24
434:2019-04-22
410:2017-11-25
370:2018-01-31
347:2013-11-10
262:2019-04-22
160:NeuroImage
96:References
1626:Pregnancy
1505:Brain PET
1473:gamma ray
1409:DMSA scan
1263:Obstetric
1156:diffusion
1151:Sequences
1129:perfusion
1021:Pulmonary
968:Cone beam
862:Pyelogram
662:1933-0693
564:1933-0693
526:ignored (
516:cite book
500:1662-3924
305:1933-7213
231:1558-254X
180:1053-8119
136:1524-4040
1644:Category
1496:positron
1016:Coronary
670:26047420
572:22381003
508:24923395
378:citation
323:17599699
239:20304721
188:18495497
144:22513841
77:See also
41:neuronal
1543:Optical
1525:PET-MRI
1305:Carotid
1300:Scrotal
1194:doppler
1124:Cardiac
1033:Thyroid
977:Targets
928:CT scan
314:2041910
196:2660208
52:History
31:) is a
1520:PET-CT
1295:Breast
1290:Rectal
1214:duplex
1146:Breast
983:Heart
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1547:Laser
1469:SPECT
1278:renal
1107:Brain
1058:Other
758:X-ray
192:S2CID
1315:FAST
1028:Head
666:PMID
658:ISSN
568:PMID
560:ISSN
528:help
504:PMID
496:ISSN
486:ISBN
384:link
319:PMID
301:ISSN
235:PMID
227:ISSN
184:PMID
176:ISSN
140:PMID
132:ISSN
29:HDFT
1492:PET
1460:ECT
1458:3D/
1340:2D/
1241:ICE
1236:TEE
1231:TTE
1099:MRI
830:DXR
826:DXA
821:KUB
816:AXR
804:CXR
648:doi
644:123
552:doi
548:116
478:doi
309:PMC
293:doi
219:doi
168:doi
124:doi
46:DTI
37:MRI
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