34:
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The success of ANPs and widespread use in HIV drugs brought IOCB significant financial resources making it the richest research institution in the Czech
Republic, allowing to extend and refurbish its campus and grow significantly. Its general income from licenses in 2021 was around USD 130 mil.
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and has been renamed multiple times. The official date that is considered as the establishment of IOCB is the year 1953, when the institute was renamed
Institute of Organic Chemistry and incorporated into newly established
1038:
994:
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The research is conducted by approximately 50 independent groups divided into several categories according to their main research focus, type, and status:
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In addition to basic research, IOCB has been active in applied research and practical applications, particularly in medicinal chemistry.
514:"IOCB Prague - Excellent Basic Research and Successful Applications: IOCB Prague - Excellent Basic Research and Successful Applications"
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453:
456:. In 1955, the institute was renamed to Chemical Institute of CAS. The institute was finally renamed to IOCB in 1993, after the
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developed by Gilead
Sciences were used in multiple drugs used for the treatment of HIV/AIDS and chronic hepatitis B, e.g.
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before the establishment of CAS. The original institute was established under the
Faculty of Chemistry of
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185:. The institute also takes part in university education, supervising master's and doctoral theses.
742:"Biochemie je v Česku na špičce. Bývalé působiště Antonína Holého mělo loni čtyřmiliardové příjmy"
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Dějiny Ústavu organické chemie a biochemie AV ČR, M. Franc a kolektiv, MÚA AV ČR 2013, kap. I
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and their analogues, eg. the development of first method for industrial production of human
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The original institute that has later turned into IOCB was established at the end of the
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This Czech
Republic university, college or other education institution article is a
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Institute of
Organic Chemistry and Biochemistry of the Czech Academy of Sciences
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Institute of
Organic Chemistry and Biochemistry of the Czech Academy of Sciences
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Status: junior, senior, honorary, distinguished emeritus, distinguished
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Cold War
Triangle : How Scientists in East and West Tamed HIV
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431:, as well as an ointment Dermazulen based on a natural compound
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and neighboring disciplines, mostly oriented at applications in
155:Ústav organické chemie a biochemie Akademie věd České republiky
26:Ústav organické chemie a biochemie Akademie věd České republiky
692:"Vědci jako byznysmeni. Elitní ústav loni vydělal 780 milionů"
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161:(CAS). The institute centers around research in the fields of
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Type: research, research-service, targeted research, service
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Institute of
Organic Chemistry and Biochemistry of the CAS
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718:"The Greatest Science Story in the Czech Republic"
722:Research & Development in the Czech Republic
815:"Lysin-vasopressin, Terlipressin, Desmopressin"
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1019:Science and technology in the Czech Republic
896:"60 let Ústavu organické chemie a biochemie"
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603:: CS1 maint: location missing publisher (
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1029:Research institutes in the Czech Republic
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482:"Rejstřík veřejných výzkumných institucí"
619:"Renowned HIV scientist Holy dies at 75"
415:, development of its analogues, such as
1024:Research institutes established in 1953
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373:compounds which became approved drugs:
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298:, approved as a drug for treatment of
1044:1953 establishments in Czechoslovakia
638:. Baltimore, Maryland: Project Muse.
518:European Journal of Organic Chemistry
512:Hostomský, Zdeněk, ed. (2018-10-09).
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449:Czech Technical University in Prague
157:) is a research institute under the
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967:. You can help Knowledge (XXG) by
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400:Among its other achievements are
262:Its most significant results are
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557:"Research groups of IOCB Prague"
454:Czechoslovak Academy of Sciences
266:antivirals (ANPs) discovered by
193:IOCB's research in oriented on
369:At IOCB originated also other
316:tenofovir alafenamide fumarate
270:at IOCB in collaboration with
264:acyclic nucleotide phosphonate
1:
458:dissolution of Czechoslovakia
312:tenofovir disoproxil fumarate
282:into approved drugs, include
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581:Research at IOCB Prague 2022
716:Pašek, Roman (2017-04-25).
54:Public research institution
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229:, bioconjugate chemistry,
1014:Czech Academy of Sciences
767:"Azacitidine, Decitabine"
460:and establishment of the
377:used in the treatment of
288:cytomegalovirus retinitis
159:Czech Academy of Sciences
31:
24:
791:"Dihydroxypropyladenine"
632:Loeckx, Renilde (2017).
419:, or the development of
406:neurohypophysial hormone
387:myelodysplastic syndrome
244:Cluster: CHEM, BIO, PHYS
25:
16:Czech research institute
1054:Europe university stubs
839:"Oxytocin, Carbetocin"
748:(in Czech). 2022-07-08
531:10.1002/ejoc.201801344
402:human peptide hormones
379:acute myeloid leukemia
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934:50.10556°N 14.39139°E
389:, both discovered by
280:Gilead Sciences, Inc.
395:herpes simplex virus
322:(approved in 2001),
310:. Its prodrug forms
223:analytical chemistry
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900:Akademický bulletin
207:medicinal chemistry
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939:50.10556; 14.39139
46:IOCB Prague, ÚOCHB
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645:978-94-6166-245-3
590:978-80-86241-68-5
524:(37): 5076–5079.
421:Lysin-vasopressin
332:Complera/Eviplera
227:materials science
199:organic chemistry
163:organic chemistry
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276:Rega Institute
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698:. 2019-07-11
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489:. Retrieved
486:rvvi.msmt.cz
485:
476:
442:
429:Desmopressin
425:Terlipressin
399:
368:
364:
268:Antonín Holý
261:
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211:biochemistry
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167:biochemistry
146:
142:
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136:www.uochb.cz
937: /
867:IOCB Prague
843:IOCB Prague
819:IOCB Prague
795:IOCB Prague
771:IOCB Prague
746:CzechCrunch
672:IOCB Prague
668:"Tenofovir"
561:IOCB Prague
433:Guaiazulene
383:Azacytidine
300:hepatitis B
215:theoretical
175:environment
147:IOCB Prague
84:Total staff
70:USD 60 mil.
59:Established
1008:Categories
925:14°23′29″E
905:2022-05-01
872:2022-08-05
848:2022-08-05
824:2022-08-05
800:2022-08-05
776:2022-08-05
752:2022-08-05
727:2022-08-05
702:2022-08-05
677:2022-08-05
654:1009361134
566:2022-08-05
491:2022-05-01
468:References
417:Carbetocin
375:Decitabine
371:nucleoside
294:patients,
203:bioorganic
42:Other name
922:50°6′20″N
599:cite book
540:240081214
308:tenofovir
284:cidofovir
274:from the
409:oxytocin
362:(2018).
358:(2018),
356:Biktarvy
354:(2016),
350:(2016),
346:(2016),
342:(2015),
338:(2012),
336:Stribild
334:(2011),
330:(2006),
326:(2004),
296:adefovir
219:physical
189:Research
171:medicine
115:Location
75:Director
439:History
360:Symtuza
352:Vemlidy
348:Descovy
344:Odefsey
340:Genvoya
328:Atripla
324:Truvada
304:Hepsera
133:Website
696:Forbes
652:
642:
587:
538:
427:, and
320:Viread
306:, and
255:Impact
221:, and
120:Prague
67:Budget
536:S2CID
151:Czech
965:stub
650:OCLC
640:ISBN
605:link
585:ISBN
522:2018
385:for
381:and
314:and
292:AIDS
205:and
181:and
173:and
110:~230
88:~950
62:1953
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526:doi
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290:in
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183:HBV
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
