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Focal seizure

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400:, often beginning with the fingers. This is felt as a tingling sensation, or a feeling of waves through the fingers when touched together. They then affect the hand and move on to more proximal areas on the same side of the body. Symptoms often associated with a Jacksonian seizure are sudden head and eye movements, tingling, numbness, smacking of the lips, and sudden muscle contractions. Typically, any of these actions can be seen as a normal movement, without being associated with the seizure occurring. They occur at no particular moment and last only briefly. They may result in secondary generalized seizure involving both hemispheres. They can also start at the feet, manifesting as 163: 36: 309:
Simple partial seizures are a very subjective experience, and the symptoms vary greatly between people. Since symptoms can be subtle, diagnosis can be delayed by months or years. The symptoms of these seizures can also be misconstrued as auras, especially for epileptics with multiple types of seizure
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Most people with focal seizures due to epilepsy require medications to manage the condition. Not all epileptics find that the medications given are effective at preventing seizures; approximately 30% cannot keep their seizures in remission. A newer pharmaceutical approach using immunomodulator drugs
479:) surrounding the seizural event. The person may still be able to perform routine tasks such as walking, although such movements are not purposeful or planned. Witnesses may not recognize that anything is wrong, and the person may or may not realize that he experienced a seizure. 513:
and atrophy. Complex partial seizures occur when excessive and synchronous electrical brain activity causes the impaired awareness and responsiveness. The abnormal electrical activity might spread to the rest of the brain and cause a focal to bilateral seizure or a generalized
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In focal onset aware seizures, a small part of one of the lobes may be affected and the person remains conscious. This can often be a precursor to a larger focal onset impaired awareness seizure; in such cases, the focal aware seizure is usually called an
195:– the frontal, temporal, parietal and occipital lobes. A focal seizure is generated in and affects just one part of the brain – a whole hemisphere or part of a lobe. Symptoms will vary according to where the seizure occurs. When seizures occur in the 1007: 988: 297:. People who have focal aware seizures remain conscious. Focal aware seizures often precede larger focal impaired awareness seizures, where the abnormal electrical activity spreads to a larger area of the brain. This can result in a 527:
in addition to standard medication treatments has been suggested and there is some evidence that this approach may reduce the frequency of focal seizures. It is not clear if this medicine is well tolerated in adults and children.
314:). A simple partial seizure may go unnoticed by others or shrugged off by the patient as merely a "funny turn." Focal aware seizures usually start suddenly and are very brief, typically lasting 60 to 120 seconds. 1540: 594: 1926: 1921: 1938: 1916: 1089: 732:
Pellinen, Jacob; Tafuro, Erica; Yang, Annie; Price, Dana; Friedman, Daniel; Holmes, Manisha; Barnard, Sarah; Detyniecki, Kamil; Hegde, Manu; Hixson, John; Haut, Sheryl (2020).
1285: 518:. The newer classification of 2017 groups only focal and generalized seizures, and generalized seizures are those that involve both sides of the brain from the onset. 2019: 369:
Hallucinations may occur during focal aware seizures, but they are differentiated from psychotic symptoms by the sufferer's awareness that they are hallucinations.
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A focal impaired awareness seizure affects a larger part of the hemisphere and the person may lose consciousness.
46: 2399: 1883: 1851: 1803: 1652: 1231: 506: 635: 515: 266: 2195: 1950: 1724: 1138: 1026: 86: 1955: 419:, whose studies led to the discovery of the seizures' initiation point (in the primary motor cortex) in 1863. 2160: 2125: 1888: 1644: 1462: 1314: 1304: 1148: 2443: 2175: 2155: 2095: 1820: 1812: 1767: 1443: 1415: 1263: 611: 509:. Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal 409: 377:
Jacksonian march or Jacksonian seizure is a phenomenon in which a simple partial seizure spreads from the
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If a focal seizure spreads from one hemisphere to the other side of the brain, this will give rise to a
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Panebianco, Mariangela; Walker, Lauren; Marson, Anthony G (2023-10-16). Cochrane Epilepsy Group (ed.).
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together with painful cramps, due to the signals from the brain. Because it is a partial seizure, the
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or a change in the perceived size of objects. Once consciousness is impaired, the person may display
393: 298: 396:. Uniquely, they travel through the primary motor cortex in succession, affecting the corresponding 310:
diagnosis. This is due to the varying locations of the brain in which the seizures originate (e.g.,
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altered sense of hearing, smelling, tasting, seeing, and tactile perception (sensory
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is of normal consciousness. Jacksonian seizures are named after their discoverer,
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that affect initially only one hemisphere of the brain. The brain is divided into
1031: 475:, such as lip smacking, chewing or swallowing. There may also be loss of memory ( 1217: 1178: 1120: 1050: 662: 498: 416: 401: 294: 269:. Individuals with multiple focal seizures typically have a condition known as 216: 35: 832: 392:
Jacksonian seizures are initiated with abnormal electrical activity within the
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face (on same side of body). They involve a progression of the location of the
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in the brain, which leads to a "march" of the motor presentation of symptoms.
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sudden and inexplicable feelings of fear, anger, sadness, happiness or nausea
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A complex partial seizure is a seizure that is associated with unilateral
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Spinal muscular atrophy with lower extremity predominance (SMALED)
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a sense of spatial distortion—near objects may appear to be distant
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As of 2017, focal seizures are split into two main categories,
467:. The aura might also occur as a visual disturbance, such as 277:
is one that involves both sides of the brain from the onset.)
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Steven C. Schachter, MD; Joseph I. Sirven, MD (July 2013).
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Trescher, William H., and Ronald P. Lescher 2000, p. 1747.
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Trescher, William H., and Ronald P. Lescher 2000, p. 1750.
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Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.
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Trescher, William H., and Ronald P. Lescher 2000, p. 1749.
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Trescher, William H., and Ronald P. Lescher 2000, p. 1748.
265:. The person will become unconscious and may experience a 874: 872: 870: 289:
that affect only a small region of the brain, often the
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may be experienced. When seizures are localized to the
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Some common symptoms of a simple partial seizure are:
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or responsiveness, i.e. alteration of consciousness.
341:), or feeling as though the environment is not real ( 970: 2380: 2344: 2290: 2267: 2209: 2143: 2134: 2111: 2080: 2039: 1834: 1811: 1802: 1795: 1750: 1700: 1672: 1643: 1609: 1571: 1560: 1526: 1504: 1429: 1239: 1230: 1216: 1176: 1119: 1110: 1041: 974: 940:"Immunomodulatory interventions for focal epilepsy" 150: 142: 137: 60:. Unsourced material may be challenged and removed. 505:regions. A common associated brain abnormality is 447:Complex partial seizures are often preceded by an 816:"Dorlands Medical Dictionary:jacksonian epilepsy" 486:of the brain. They most commonly arise from the 345:) or dissociation from the environment or self ( 620:, Epilepsy Society - Are all seizures the same. 27:Seizures which affect only one brain hemisphere 914:"International League Against Epilepsy." 2008. 482:Complex partial seizures might arise from any 330:experiencing of unusual feelings or sensations 2013: 1083: 8: 365:labored speech or inability to speak at all 2140: 2020: 2006: 1998: 1808: 1799: 1568: 1236: 1227: 1116: 1090: 1076: 1068: 971: 630: 628: 626: 219:may occur. With seizures occurring in the 161: 134: 636:"2017 Revised Classification of Seizures" 120:Learn how and when to remove this message 2388:Citizens United for Research in Epilepsy 572:Bradley's neurology in clinical practice 944:Cochrane Database of Systematic Reviews 827: 825: 785: 783: 657: 655: 653: 651: 649: 536: 293:or structures found there, such as the 1879:Distal hereditary motor neuronopathies 1552:Template:Demyelinating diseases of CNS 933: 931: 929: 7: 2305:Dentatorubral–pallidoluysian atrophy 1730:Idiopathic intracranial hypertension 146:Partial seizures, localized seizures 58:adding citations to reliable sources 2352:Sudden unexpected death in epilepsy 709:Amit M. Shelat (27 February 2016). 2282:Complex partial status epilepticus 1961:Infantile progressive bulbar palsy 25: 2367:Psychogenic non-epileptic seizure 2239:Benign familial neonatal seizures 2191:Sleep-related hypermotor epilepsy 1664:Template:Cerebrovascular diseases 1467:Frontotemporal lobar degeneration 570:Bradley, Walter G. (2012). "67". 327:sensations of falling or movement 1684:For more detailed coverage, see 1662:For more detailed coverage, see 1633:For more detailed coverage, see 1599:For more detailed coverage, see 1550:For more detailed coverage, see 34: 239:. What was previously termed a 45:needs additional citations for 2327:Early myoclonic encephalopathy 2300:Progressive myoclonus epilepsy 956:10.1002/14651858.CD009945.pub3 792:Epilepsy Questions and Answers 551:. The Johns Hopkins University 237:focal onset impaired awareness 1: 1977:Amyotrophic lateral sclerosis 1862:Hereditary spastic paraplegia 1720:Normal pressure hydrocephalus 241:secondary generalised seizure 2277:Epilepsia partialis continua 1946:Progressive muscular atrophy 600:Dorland's Medical Dictionary 402:tingling or pins and needles 381:part of the limb toward the 285:Simple partial seizures are 2332:Juvenile myoclonic epilepsy 2310:Unverricht–Lundborg disease 1456:Primary progressive aphasia 2460: 2249:Myoclonic astatic epilepsy 1778:Hashimoto's encephalopathy 1484:Posterior cortical atrophy 1305:Striatonigral degeneration 1156:Cavernous sinus thrombosis 545:"Partial (Focal) Seizures" 263:focal to bilateral seizure 245:focal to bilateral seizure 2400:Epilepsy Action Australia 1884:Spinal muscular atrophies 1852:Primary lateral sclerosis 1710:Intracranial hypertension 1490:Creutzfeldt–Jakob disease 711:"Partial (focal) seizure" 507:mesial temporal sclerosis 2362:Landau–Kleffner syndrome 2196:Panayiotopoulos syndrome 1951:Progressive bulbar palsy 1742:Intracranial hypotension 1725:Choroid plexus papilloma 1139:Herpesviral encephalitis 423:Complex partial seizures 2244:Lennox–Gastaut syndrome 2126:Epilepsy and employment 1463:Frontotemporal dementia 1149:Encephalitis lethargica 878:Murro, Anthony M. 2006. 685:"Simple Focal Seizures" 431:involvement and causes 321:preserved consciousness 281:Simple partial seizures 2176:Temporal lobe epilepsy 2096:Electroencephalography 1768:Hepatic encephalopathy 549:Johns Hopkins Medicine 410:John Hughlings Jackson 271:temporal lobe epilepsy 2181:Frontal lobe epilepsy 1826:Ataxia–telangiectasia 1783:Static encephalopathy 1506:Mitochondrial disease 1344:Spasmodic torticollis 1254:Basal ganglia disease 191:, each consisting of 2417:Epilepsy Research UK 2201:Vertiginous epilepsy 2121:Epilepsy and driving 2072:Epilepsy in children 1773:Toxic encephalopathy 1479:Lewy bodies dementia 905:Trepeta, Scott 2007. 794:. Merit Publishing. 516:tonic–clonic seizure 394:primary motor cortex 299:tonic-clonic seizure 267:tonic–clonic seizure 54:improve this article 2405:Epilepsy Foundation 2372:Epilepsy in animals 2052:Aura (warning sign) 1821:Friedreich's ataxia 1204:Meningoencephalitis 1144:Limbic encephalitis 689:Epilepsy Foundation 667:Epilepsy Foundation 663:"Types of Seizures" 640:Epilepsy Foundation 493:, particularly the 429:cerebral hemisphere 275:generalized seizure 18:Jacksonian seizures 2292:Myoclonic epilepsy 2269:Status epilepticus 1857:Pseudobulbar palsy 1595:Status epilepticus 1546:Multiple sclerosis 1383:Myoclonic epilepsy 1246:movement disorders 1192:Acute disseminated 1134:Viral encephalitis 1042:External resources 616:2013-08-09 at the 181:localized seizures 2431: 2430: 2345:Related disorders 2340: 2339: 2186:Rolandic epilepsy 1995: 1994: 1991: 1990: 1987: 1986: 1791: 1790: 1696: 1695: 1635:Template:Headache 1601:Template:Epilepsy 1522: 1521: 1496:Vascular dementia 1339:Status dystonicus 1212: 1211: 1187:Encephalomyelitis 1065: 1064: 790:Hart, YM (2007). 750:10.1111/epi.16707 744:(12): 2643–2652. 595:"partial seizure" 465:depersonalization 358:(familiarity) or 347:depersonalization 233:focal onset aware 170: 169: 132:Medical condition 130: 129: 122: 104: 16:(Redirected from 2451: 2422:Epilepsy Society 2411:Epilepsy Outlook 2254:Epileptic spasms 2166:Gelastic seizure 2141: 2067:Neonatal seizure 2022: 2015: 2008: 1999: 1809: 1800: 1758:Brain herniation 1569: 1409:Intention tremor 1404:Essential tremor 1269:Postencephalitic 1237: 1228: 1117: 1098:Diseases of the 1092: 1085: 1078: 1069: 972: 960: 959: 935: 924: 921: 915: 912: 906: 903: 897: 894: 888: 885: 879: 876: 865: 862: 849: 846: 840: 829: 820: 819: 812: 806: 805: 787: 778: 777: 729: 723: 722: 720: 718: 706: 700: 699: 697: 695: 680: 671: 670: 659: 644: 643: 632: 621: 609: 603: 592: 586: 585: 567: 561: 560: 558: 556: 541: 373:Jacksonian march 243:is now termed a 177:partial seizures 166: 165: 135: 125: 118: 114: 111: 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203:, a feeling of 189:two hemispheres 160: 133: 126: 115: 109: 106: 69:"Focal seizure" 63: 61: 51: 39: 28: 23: 22: 15: 12: 11: 5: 2457: 2455: 2447: 2446: 2436: 2435: 2429: 2428: 2426: 2425: 2419: 2414: 2408: 2402: 2397: 2391: 2384: 2382: 2378: 2377: 2375: 2374: 2369: 2364: 2359: 2357:Todd's paresis 2354: 2348: 2346: 2342: 2341: 2338: 2337: 2335: 2334: 2329: 2324: 2323: 2322: 2320:Lafora disease 2317: 2315:MERRF syndrome 2312: 2307: 2296: 2294: 2288: 2287: 2285: 2284: 2279: 2273: 2271: 2265: 2264: 2262: 2261: 2256: 2251: 2246: 2241: 2236: 2231: 2229:Atonic seizure 2226: 2221: 2215: 2213: 2207: 2206: 2204: 2203: 2198: 2193: 2188: 2183: 2178: 2173: 2169: 2168: 2163: 2158: 2156:Simple partial 2153: 2149: 2147: 2138: 2132: 2131: 2129: 2128: 2123: 2117: 2115: 2109: 2108: 2106: 2105: 2103:Epileptologist 2100: 2099: 2098: 2090: 2084: 2082: 2078: 2077: 2075: 2074: 2069: 2064: 2059: 2054: 2049: 2043: 2041: 2037: 2036: 2027: 2025: 2024: 2017: 2010: 2002: 1993: 1992: 1989: 1988: 1985: 1984: 1982: 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1588: 1586: 1583: 1582: 1580: 1578: 1574: 1570: 1567: 1565: 1559: 1553: 1549: 1547: 1544: 1542: 1539: 1537: 1534: 1533: 1531: 1529: 1528:Demyelinating 1525: 1515: 1512: 1511: 1509: 1507: 1503: 1497: 1494: 1493: 1492: 1491: 1485: 1482: 1480: 1477: 1473: 1470: 1469: 1468: 1464: 1461: 1457: 1454: 1450: 1447: 1446: 1445: 1442: 1441: 1440: 1437: 1436: 1434: 1432: 1428: 1422: 1419: 1417: 1416:Restless legs 1414: 1410: 1407: 1405: 1402: 1401: 1400: 1397: 1396: 1391: 1388: 1384: 1381: 1380: 1379: 1376: 1372: 1369: 1368: 1367: 1364: 1362: 1359: 1355: 1354:Blepharospasm 1352: 1350: 1347: 1345: 1342: 1340: 1337: 1336: 1335: 1332: 1331: 1330: 1327: 1326: 1321: 1318: 1316: 1313: 1311: 1310:Hemiballismus 1308: 1306: 1303: 1299: 1296: 1295: 1294: 1291: 1287: 1284: 1283: 1282: 1279: 1275: 1272: 1270: 1267: 1265: 1262: 1261: 1260: 1257: 1256: 1255: 1252: 1251: 1249: 1247: 1242: 1238: 1235: 1233: 1229: 1226: 1224: 1219: 1215: 1205: 1202: 1200: 1197: 1193: 1190: 1189: 1188: 1185: 1184: 1182: 1180: 1175: 1167: 1164: 1163: 1162: 1161:Brain abscess 1159: 1157: 1154: 1150: 1147: 1145: 1142: 1140: 1137: 1135: 1132: 1131: 1130: 1127: 1126: 1124: 1122: 1118: 1115: 1113: 1109: 1105: 1101: 1093: 1088: 1086: 1081: 1079: 1074: 1073: 1070: 1057: 1053: 1052: 1048: 1047: 1044: 1040: 1033: 1029: 1028: 1024: 1022: 1018: 1014: 1013: 1009: 1005: 1003: 999: 995: 994: 990: 986: 985: 982: 977: 973: 966: 957: 953: 949: 945: 941: 934: 932: 930: 926: 920: 917: 911: 908: 902: 899: 893: 890: 884: 881: 875: 873: 871: 867: 861: 859: 857: 855: 851: 845: 842: 839: 838:Who Named It? 835: 834: 828: 826: 822: 817: 811: 808: 803: 797: 793: 786: 784: 780: 775: 771: 767: 763: 759: 755: 751: 747: 743: 739: 735: 728: 725: 713:. MedlinePlus 712: 705: 702: 690: 686: 679: 677: 673: 668: 664: 658: 656: 654: 652: 650: 646: 641: 637: 631: 629: 627: 623: 619: 615: 612: 608: 605: 602: 601: 596: 591: 588: 583: 577: 573: 566: 563: 550: 546: 540: 537: 530: 528: 521: 519: 517: 512: 508: 504: 500: 496: 492: 491:temporal lobe 489: 485: 480: 478: 474: 470: 469:tunnel vision 466: 462: 458: 454: 450: 442: 440: 438: 434: 430: 422: 420: 418: 415: 411: 407: 403: 399: 395: 390: 388: 384: 380: 372: 370: 364: 361: 357: 354: 351: 348: 344: 343:derealization 340: 336: 332: 329: 326: 323: 320: 319: 318: 315: 313: 304: 302: 300: 296: 292: 288: 280: 278: 276: 272: 268: 264: 259: 256: 254: 248: 246: 242: 238: 234: 226: 224: 222: 218: 214: 210: 209:parietal lobe 206: 202: 201:temporal lobe 198: 194: 190: 186: 182: 178: 175:(also called 174: 164: 158: 155: 153: 149: 145: 141: 138:Focal seizure 136: 124: 121: 113: 110:February 2013 102: 99: 95: 92: 88: 85: 81: 78: 74: 71: â€“  70: 66: 65:Find sources: 59: 55: 49: 48: 43:This article 41: 37: 32: 31: 19: 2219:Tonic–clonic 2144: 1971: 1870: 1843: 1804:Degenerative 1584: 1541:Inflammatory 1488: 1421:Stiff-person 1259:Parkinsonism 1232:Degenerative 1129:Encephalitis 1112:Inflammation 1102:, primarily 1049: 1025: 1006: 987: 947: 943: 919: 910: 901: 892: 883: 844: 831: 810: 791: 741: 737: 727: 715:. Retrieved 704: 692:. Retrieved 688: 666: 639: 607: 598: 590: 571: 565: 553:. Retrieved 548: 539: 525: 481: 446: 443:Presentation 426: 391: 376: 368: 316: 308: 305:Presentation 284: 262: 260: 257: 249: 244: 240: 236: 232: 230: 197:frontal lobe 180: 176: 172: 171: 116: 107: 97: 90: 83: 76: 64: 52:Please help 47:verification 44: 2211:Generalised 1956:Fazio–Londe 1796:Both/either 1590:Generalised 1449:Early-onset 1444:Alzheimer's 1179:spinal cord 1051:MedlinePlus 555:1 September 503:neocortical 499:hippocampus 473:automatisms 417:neurologist 383:ipsilateral 143:Other names 2234:Automatism 2081:Management 1564:paroxysmal 1536:Autoimmune 1329:Dyskinesia 1199:Meningitis 1177:Brain and 531:References 433:impairment 295:hippocampi 193:four lobes 80:newspapers 1561:Episodic/ 1439:Tauopathy 1390:Akathisia 1378:Myoclonus 1361:Athetosis 1293:Tauopathy 833:synd/3332 774:224811014 758:1528-1167 738:Epilepsia 717:31 August 694:31 August 522:Treatment 457:jamais vu 437:awareness 360:jamais vu 335:illusions 157:Neurology 152:Specialty 2438:Category 2172:Epilepsy 2152:Seizures 2033:epilepsy 2029:Seizures 1927:SMALED2B 1922:SMALED2A 1619:Migraine 1611:Headache 1577:epilepsy 1573:Seizures 1431:Dementia 1334:Dystonia 766:33078409 614:Archived 495:amygdala 461:euphoria 459:, fear, 312:Rolandic 287:seizures 217:tingling 213:numbness 185:seizures 1939:SMA-PME 1934:SMA-PCH 1917:SMALED1 1629:Tension 1624:Cluster 1349:Meige's 1166:Amoebic 1032:D004828 511:gliosis 477:amnesia 453:dĂ©jĂ  vu 414:English 398:muscles 387:seizure 356:dĂ©jĂ  vu 205:dĂ©jĂ  vu 94:scholar 2040:Basics 1658:Stroke 1472:Pick's 1399:Tremor 1366:Chorea 1056:000697 950:(10). 798:  772:  764:  756:  578:  501:, and 488:mesial 379:distal 235:, and 183:) are 159:  96:  89:  82:  75:  67:  2145:Focal 1972:both: 1904:DSMA1 1899:SMAX2 1894:SMAX1 1874:only: 1847:only: 1751:Other 1673:Other 1585:Focal 1218:Brain 1121:Brain 1021:345.5 1017:345.4 1002:G40.2 998:G40.0 770:S2CID 412:, an 273:. (A 227:Types 101:JSTOR 87:books 2424:(UK) 2413:(UK) 2407:(US) 2396:(UK) 2390:(US) 2031:and 1575:and 1286:PKAN 1281:NBIA 1027:MeSH 1012:9-CM 948:2023 796:ISBN 762:PMID 754:ISSN 719:2016 696:2016 576:ISBN 557:2016 484:lobe 449:aura 253:aura 211:, a 179:and 73:news 1889:SMA 1872:LMN 1845:UMN 1836:MND 1702:CSF 1653:TIA 1298:PSP 1274:NMS 1243:and 1104:CNS 1008:ICD 989:ICD 952:doi 836:at 746:doi 597:at 463:or 435:of 337:or 215:or 56:by 2440:: 1813:SA 1320:OA 1315:HD 1264:PD 1054:: 1030:: 1015:: 996:: 993:10 946:. 942:. 928:^ 869:^ 853:^ 824:^ 782:^ 768:. 760:. 752:. 742:61 740:. 736:. 687:. 675:^ 665:. 648:^ 638:. 625:^ 547:. 497:, 455:, 301:. 255:. 247:. 2021:e 2014:t 2007:v 1465:/ 1220:/ 1091:e 1084:t 1077:v 1019:- 1010:- 1000:- 991:- 981:D 958:. 954:: 818:. 804:. 776:. 748:: 721:. 698:. 669:. 642:. 584:. 559:. 349:) 123:) 117:( 112:) 108:( 98:· 91:· 84:· 77:· 50:. 20:)

Index

Jacksonian seizures

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seizures
two hemispheres
four lobes
frontal lobe
temporal lobe
déjà vu
parietal lobe
numbness
tingling
occipital lobe
aura
tonic–clonic seizure
temporal lobe epilepsy
generalized seizure
seizures

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