Knowledge (XXG)

Generalized epilepsy

Source đź“ť

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Vajda, FJ; O'brien, TJ; Hitchcock, A; Graham, J; Cook, M; Lander, C; Eadie, MJ (November 2004). "Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy".
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Most generalized epilepsy starts during childhood. While some patients outgrow their epilepsy during adolescence and no longer need medication, in others, the condition remains for life, thereby requiring lifelong medication and monitoring.
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Valproate, a relatively old drug, is often considered the first-line treatment. It is highly effective, but its association with fetal malformations when taken in pregnancy limits its use in young women.
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that impairs consciousness and distorts the electrical activity of the whole or a larger portion of the brain (which can be seen, for example, on
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GĂłmez-Porro, Pablo; Serrano, Angel Aledo; Toledano, Rafael; GarcĂ­a-Morales, Irene; Gil-Nagel, Antonio (October 2018).
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Seven anti-epileptic drugs are approved for use in cases of suspected primary generalized epilepsy:
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Epilepsy syndrome that is characterised by generalised seizures with no apparent cause
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because the epilepsy is the originally diagnosed condition itself, as opposed to
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All anti-epileptic drugs (including the above) can be used in cases of
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Spinal muscular atrophy with lower extremity predominance (SMALED)
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Generalized seizures occur in various seizure syndromes, including
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epilepsy, which occurs as a symptom of a diagnosed condition.
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characterised by generalised seizures with no apparent cause.
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Archived from 257: 241:partial seizures 163:infantile spasms 159:absence epilepsy 124:absence seizures 95:, are a type of 91:, as opposed to 53: 33: 21: 1887: 1886: 1882: 1881: 1880: 1878: 1877: 1876: 1862: 1861: 1860: 1855: 1822:Epilepsy Action 1804: 1764: 1714: 1691: 1687:Febrile seizure 1652:Absence seizure 1633: 1589:Complex partial 1558: 1541:Personal issues 1535: 1520:Investigations 1516:Anticonvulsants 1504: 1490:Epileptogenesis 1485:Postictal state 1463: 1454: 1424: 1411: 1337:Congenital DSMA 1258: 1215: 1174: 1120: 1108:Sleep disorders 1096: 1073:Cerebrovascular 1067: 1033: 990: 984: 946: 928: 853: 799:Choreoathetosis 672: 649: 636: 600: 534: 524: 494: 489: 488: 439: 425: 420: 419: 388: 387: 383: 378: 374: 338: 337: 333: 324: 322: 313: 312: 308: 299: 297: 288: 287: 283: 274: 272: 259: 258: 254: 249: 188: 179: 140:atonic seizures 132:clonic seizures 120: 31: 28: 23: 22: 15: 12: 11: 5: 1885: 1883: 1875: 1874: 1872:Epilepsy types 1864: 1863: 1857: 1856: 1854: 1853: 1847: 1842: 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1199: 1197: 1194: 1192: 1191:Reye syndrome 1189: 1187: 1184: 1183: 1181: 1177: 1171: 1168: 1166: 1163: 1159: 1156: 1154: 1151: 1149: 1146: 1144: 1143:Hydrocephalus 1141: 1140: 1139: 1136: 1135: 1133: 1131: 1127: 1115: 1111: 1110: 1109: 1106: 1105: 1103: 1099: 1093: 1089: 1087: 1084: 1082: 1079: 1078: 1076: 1074: 1070: 1064: 1060: 1058: 1055: 1053: 1050: 1048: 1045: 1044: 1042: 1040: 1036: 1030: 1026: 1024: 1021: 1019: 1016: 1014: 1011: 1010: 1008: 1006: 1002: 998: 995: 993: 987: 981: 977: 975: 972: 970: 967: 965: 962: 961: 959: 957: 956:Demyelinating 953: 943: 940: 939: 937: 935: 931: 925: 922: 921: 920: 919: 913: 910: 908: 905: 901: 898: 897: 896: 892: 889: 885: 882: 878: 875: 874: 873: 870: 869: 868: 865: 864: 862: 860: 856: 850: 847: 845: 844:Restless legs 842: 838: 835: 833: 830: 829: 828: 825: 824: 819: 816: 812: 809: 808: 807: 804: 800: 797: 796: 795: 792: 790: 787: 783: 782:Blepharospasm 780: 778: 775: 773: 770: 768: 765: 764: 763: 760: 759: 758: 755: 754: 749: 746: 744: 741: 739: 738:Hemiballismus 736: 734: 731: 727: 724: 723: 722: 719: 715: 712: 711: 710: 707: 703: 700: 698: 695: 693: 690: 689: 688: 685: 684: 683: 680: 679: 677: 675: 670: 666: 663: 661: 657: 654: 652: 647: 643: 633: 630: 628: 625: 621: 618: 617: 616: 613: 612: 610: 608: 603: 595: 592: 591: 590: 589:Brain abscess 587: 585: 582: 578: 575: 573: 570: 568: 565: 563: 560: 559: 558: 555: 554: 552: 550: 546: 543: 541: 537: 533: 529: 521: 516: 514: 509: 507: 502: 501: 498: 485: 481: 480: 476: 474: 470: 466: 465: 461: 457: 455: 451: 450: 446: 442: 441: 438: 433: 429: 422: 413: 409: 405: 401: 397: 393: 385: 382: 376: 373: 368: 364: 359: 354: 350: 346: 342: 335: 332: 320: 316: 310: 307: 295: 291: 285: 282: 271:on 2009-11-08 270: 266: 262: 256: 253: 246: 244: 242: 237: 231: 228: 226: 223: 221: 218: 216: 213: 211: 208: 206: 205:Levetiracetam 203: 201: 197: 193: 192: 191: 185: 183: 176: 174: 172: 168: 164: 160: 156: 152: 148: 143: 141: 137: 133: 129: 125: 118:Manifestation 117: 115: 113: 109: 104: 102: 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Retrieved 269:the original 264: 255: 238: 234: 194:Brand Name: 189: 180: 144: 121: 111: 107: 105: 88: 80: 79: 1639:Generalised 1384:Fazio–Londe 1224:Both/either 1018:Generalised 877:Early-onset 872:Alzheimer's 607:spinal cord 265:Med.nyu.edu 225:Lamotrigine 41:Other names 1662:Automatism 1509:Management 992:paroxysmal 964:Autoimmune 757:Dyskinesia 627:Meningitis 605:Brain and 325:2016-12-16 300:2016-12-16 275:2016-12-16 247:References 230:Perampanel 215:Topiramate 210:Zonisamide 989:Episodic/ 867:Tauopathy 818:Akathisia 806:Myoclonus 789:Athetosis 721:Tauopathy 367:1294-9361 220:Valproate 200:Felbamate 186:Treatment 177:Prognosis 112:secondary 73:Neurology 68:Specialty 1866:Category 1600:Epilepsy 1580:Seizures 1461:epilepsy 1457:Seizures 1355:SMALED2B 1350:SMALED2A 1047:Migraine 1039:Headache 1005:epilepsy 1001:Seizures 859:Dementia 762:Dystonia 412:15519862 196:Felbatol 103:, EEG). 85:epilepsy 1367:SMA-PME 1362:SMA-PCH 1345:SMALED1 1057:Tension 1052:Cluster 777:Meige's 594:Amoebic 484:D004829 108:primary 97:seizure 1468:Basics 1086:Stroke 900:Pick's 827:Tremor 794:Chorea 410:  365:  1573:Focal 1400:both: 1332:DSMA1 1327:SMAX2 1322:SMAX1 1302:only: 1275:only: 1179:Other 1101:Other 1013:Focal 646:Brain 549:Brain 473:345.1 469:345.0 454:G40.3 1852:(UK) 1841:(UK) 1835:(US) 1824:(UK) 1818:(US) 1459:and 1003:and 714:PKAN 709:NBIA 479:MeSH 464:9-CM 408:PMID 363:ISSN 1317:SMA 1300:LMN 1273:UMN 1264:MND 1130:CSF 1081:TIA 726:PSP 702:NMS 671:and 532:CNS 460:ICD 445:ICD 400:doi 353:doi 138:or 1868:: 1241:SA 748:OA 743:HD 692:PD 482:: 467:: 452:: 449:10 406:. 396:11 394:. 361:. 349:20 347:. 343:. 317:. 292:. 263:. 243:. 169:, 161:, 157:, 153:, 149:, 142:. 134:, 130:, 126:, 1449:e 1442:t 1435:v 893:/ 648:/ 519:e 512:t 505:v 471:- 462:- 447:- 437:D 414:. 402:: 369:. 355:: 328:. 303:. 278:. 20:)

Index

Generalized seizure
An electroencephalogram of a person with childhood absence epilepsy showing a seizure. The waves are black on a white background.
spike-and-wave
Specialty
Neurology
epilepsy
focal seizures
seizure
electroencephalography
absence seizures
myoclonic seizures
clonic seizures
tonic-clonic seizures
atonic seizures
myoclonic epilepsy
familial neonatal convulsions
childhood absence epilepsy
absence epilepsy
infantile spasms
Juvenile Myoclonic Epilepsy
Lennox-Gastaut syndrome
Felbatol
Felbamate
Levetiracetam
Zonisamide
Topiramate
Valproate
Lamotrigine
Perampanel
partial seizures

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