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Woo, C. M.; Lu, L.; Gholap, S. L.; Smith, D. R.; Herzon, S. B. (2010). "Development of a
Convergent Entry to the Diazofluorene Antitumor Antibiotics: Enantioselective Synthesis of Kinamycin F".
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synthesize kinamycins C, F, and J were discovered. In 2010 a method was found to allow easier synthesis of these compounds in fewer steps, making research into their properties more feasible.
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O'Hara, K. A.; Wu, X.; Patel, D.; Liang, H.; Yalowich, J. C.; Chen, N.; Goodfellow, V.; Adedayo, O.; Dmitrienko, G. I.; Hasinoff, B. B. (2007).
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Nicolaou, K. C.; Li, H.; Nold, A. L.; Pappo, D.; Lenzen, A. (2007). "Total
Synthesis of Kinamycins C, F, and J".
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Lei, X.; Porco Ja, J. (2006). "Total synthesis of the diazobenzofluorene antibiotic (-)-kinamycin C1".
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Ballard, T. E.; Melander, C. (2008). "Kinamycin-mediated DNA cleavage under biomimetic conditions".
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EMBL-EBI listing—includes links to structural formula and other properties of group members
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Description of Porco(2006) and
Nicolaou(2007) synthesis on University of Pittsburgh site
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102:"Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F"
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and are considered of interest for potential use in anti-cancer therapies.
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53:In 2006 and 2007 the means to totally and
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221:Journal of the American Chemical Society
186:Journal of the American Chemical Society
151:Journal of the American Chemical Society
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41:group. Kinamycins are known for their
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118:10.1016/j.freeradbiomed.2007.07.005
288:Nucleic acid inhibitor antibiotics
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106:Free Radical Biology and Medicine
23:Chemical structure of kinamycin A
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87:10.1016/j.tetlet.2008.03.019
16:Group of chemical compounds
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30:are a group of bacterial
258:kinamycin (CHEBI:48207)
278:Polyketide antibiotics
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35:secondary metabolites
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157:(46): 14790–14791.
75:Tetrahedron Letters
55:enantioselectively
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112:(8): 1132–1144.
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272:Categories
61:References
32:polyketide
28:Kinamycins
49:Synthesis
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