159:
59:
The "small cleaved cells" are usually centrocytes that express B-cell markers such as CD20. The disease is strongly correlated with the genetic translocation t(14;18), which results in juxtaposition of the bcl-2 proto-oncogene with the heavy chain JH locus, and thus in overexpression of bcl-2.
73:
Abe M, Wakasa H (1994). "Histogenesis and pathogenesis of follicular small cleaved cell lymphoma (FSCCL), diffuse small cleaved cell lymphoma (DSCCL) and intermediate lymphocytic lymphoma/lymphocytic lymphoma of intermediate differentiation (ILL/IDL)".
97:"Histogenesis of diffuse small cleaved cell lymphoma. An immunohistochemical and molecular genetic (bcl-2 gene) study with comparison to follicular small cleaved cell lymphoma and mantle zone lymphoma"
200:
60:
Bcl-2 is a well known anti-apoptotic gene, and thus its overexpression results in the "failure to die" motif of cancer seen in follicular lymphoma.
113:
96:
63:
Follicular lymphoma must be carefully monitored, as it often progresses into a more aggressive "Diffuse Large B-Cell
Lymphoma."
193:
129:
139:
158:
224:
143:
133:
219:
186:
17:
41:
118:
83:
170:
108:
49:
213:
40:
When used to uniquely identify a type of lymphoma, they are usually categorized as
114:
10.1002/1097-0142(19920815)70:4<821::AID-CNCR2820700417>3.0.CO;2-Y
53:
45:
166:
122:
87:
34:
95:
Abe M, Ono N, Tominaga K, Hojo H, Seto M, Fukuhara S, Wakasa H (1992).
33:
are a distinctive type of cell that appears in certain types of
174:
194:
8:
201:
187:
142:at the U.S. National Library of Medicine
132:at the U.S. National Library of Medicine
112:
130:Lymphoma,+Small+Cleaved-Cell,+Follicular
18:Lymphoma, small cleaved-cell, follicular
140:Lymphoma,+Small+Cleaved-Cell,+Diffuse
7:
155:
153:
173:. You can help Knowledge (XXG) by
25:
157:
1:
27:Cell type found in lymphomas
241:
152:
165:This article related to
144:Medical Subject Headings
134:Medical Subject Headings
76:Fukushima J Med Sci
31:Small cleaved cells
182:
181:
16:(Redirected from
232:
203:
196:
189:
161:
154:
126:
116:
91:
21:
240:
239:
235:
234:
233:
231:
230:
229:
225:Pathology stubs
210:
209:
208:
207:
150:
94:
72:
69:
28:
23:
22:
15:
12:
11:
5:
238:
236:
228:
227:
222:
220:Histopathology
212:
211:
206:
205:
198:
191:
183:
180:
179:
162:
148:
147:
137:
127:
92:
68:
67:External links
65:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
237:
226:
223:
221:
218:
217:
215:
204:
199:
197:
192:
190:
185:
184:
178:
176:
172:
168:
163:
160:
156:
151:
145:
141:
138:
135:
131:
128:
124:
120:
115:
110:
106:
102:
98:
93:
89:
85:
82:(2): 85–101.
81:
77:
71:
70:
66:
64:
61:
57:
55:
51:
47:
43:
38:
36:
32:
19:
175:expanding it
164:
149:
107:(4): 821–9.
104:
100:
79:
75:
62:
58:
39:
30:
29:
214:Categories
42:follicular
167:pathology
35:lymphoma
123:1643614
88:7642169
50:diffuse
146:(MeSH)
136:(MeSH)
121:
101:Cancer
86:
169:is a
54:C83.1
48:) or
46:C82.0
171:stub
119:PMID
84:PMID
56:) .
109:doi
216::
117:.
105:70
103:.
99:.
80:40
78:.
37:.
202:e
195:t
188:v
177:.
125:.
111::
90:.
52:(
44:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
