400:
Dupin N, Diss TL, Kellam P, Tulliez M, Du MQ, Sicard D, Weiss RA, Isaacson PG, Boshoff C (2000). "HHV-8 is associated with a plasmablastic variant of
Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma".
738:
Cesarman E, Knowles DM (1997). "Kaposi's sarcoma-associated herpesvirus: a lymphotropic human herpesvirus associated with Kaposi's sarcoma, primary effusion lymphoma, and multicentric
Castleman's disease".
98:
subtype. These plasmablasts can give rise to a spectrum of abnormalities including progression to microlymphoma (microscopic clusters of plasmablast cells) or clinical
239:
548:"Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders"
183:
in the literature, although that is a dissimilar specific entity. Similarly, this subtype is considered distinct from other lymphomas which have a plasmablastic
617:"High incidence of Kaposi sarcoma-associated herpesvirus-related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease"
596:
482:
319:
291:
249:
114:
36:
255:
507:"KSHV-associated multicentric Castleman disease: A tangle of different entities requiring multitarget treatment strategies"
196:
51:
344:"Kaposi Sarcoma-Associated Herpesvirus-Associated Malignancies: Epidemiology, Pathogenesis, and Advances in Treatment"
192:
95:
91:
658:"Unique expression pattern of viral proteins in human herpesvirus 8-positive plasmablastic lymphoma: a case report"
439:
Malnati MS, Dagna L, Ponzoni M, Lusso P (2003). "Human herpesvirus 8 (HHV-8/KSHV) and hematologic malignancies".
207:
188:
67:(HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV) has been found in some cases of multicentric
180:
137:
28:
118:
203:
64:
771:
748:
720:
679:
638:
592:
569:
528:
478:
448:
418:
414:
373:
315:
287:
245:
68:
47:
140:
of the oral cavity of AIDS which is not associated with HHV-8 infection. Despite traditional
710:
669:
628:
559:
518:
410:
363:
355:
165:
145:
110:
184:
20:
674:
657:
368:
343:
161:
122:
83:
765:
715:
698:
359:
141:
31:
in the literature, although that is a dissimilar specific entity. It has variable
17:
Large B-cell lymphoma arising in HHV8-associated multicentric
Castleman's disease
310:
Hoffman, R; Benz, EJ; Silberstein, LE; Heslop, H; Weitz, J; Anastasi, J (2012).
157:
149:
76:
72:
153:
129:
633:
616:
564:
547:
173:
169:
724:
683:
642:
573:
532:
452:
422:
377:
244:. Vol. 2 (4th ed.). International Agency for Research on Cancer.
752:
219:
106:
99:
58:
23:, recognized in the WHO 2008 classification. It is sometimes called the
523:
506:
473:
Armitage, JO; Mauch PM; Harris NL; et al. (2010). "Chapter 35".
133:
80:
55:
241:
WHO classification of tumours of haematopoietic and lymphoid tissues
282:
Jaffe, ES; Harris, NL; Vardiman, JW; Campo, E; Arber, DA (2011).
32:
117:(AIDS) but it can also occur in immunosuppression such as with
87:
615:
Oksenhendler E, Boulanger E, Galicier L, et al. (2002).
54:
of unknown cause. CD is associated with an increased risk of
342:
Bhutani M, Polizzotto MN, Uldrick TS, Yarchoan R (2015).
121:
or the elderly. The plasmablasts do not show rearranged
71:(MCD). The HHV8 can give rise to an increased number of
179:
This lymphoma subtype has sometimes been confused with
656:
Yamada M, Katano H, Yotsumoto M, et al. (2014).
505:
Carbone A, De Paoli P, Gloghini A, Vaccher E (2015).
591:(13th ed.). Lippincott Williams & Wilkins.
25:
plasmablastic form of multicentric
Castleman disease
610:
608:
587:Greer, JP; Arber DA; Glader B; et al. (2013).
477:(2nd ed.). Lippincott Williams & Wilkins.
468:
466:
464:
462:
305:
303:
210:, previously called body cavity-based lymphoma.
277:
275:
273:
271:
269:
267:
265:
500:
498:
496:
494:
434:
432:
337:
335:
333:
331:
8:
546:Du MQ, Liu H, Diss TC, et al. (2001).
395:
393:
391:
389:
387:
714:
673:
632:
563:
522:
415:10.1182/blood.V95.4.1406.004k26_1406_1412
367:
312:Hematology: Basic Principles and Practice
125:genes, and typically lack EBV infection.
230:
206:and with another subtype of lymphoma,
27:. It has sometimes been confused with
197:extracavitary HHV–8-positive lymphoma
7:
164:and inhibition of specific cellular
286:(1st ed.). Elsevier Saunders.
128:The disease predominantly affects
115:acquired immunodeficiency syndrome
109:is predominantly seen in acquired
14:
716:10.1111/j.1365-2141.2007.06879.x
699:"KSHV/HHV8-associated lymphomas"
360:10.1053/j.seminoncol.2014.12.027
176:in this lymphoma has been poor.
160:), and the possible addition of
697:Carbone A, Gloghini A (2008).
589:Wintrobe's Clinical Hematology
37:immunoglobulin variable region
1:
202:HHV8 is also associated with
86:. These plasmablasts express
238:Swerdlow, Steven H. (2008).
52:lymphoproliferative disorder
92:immunoglobulin light chains
788:
314:(6th ed.). Elsevier.
193:ALK+ large B-cell lymphoma
136:, a pattern dissimilar to
208:primary effusion lymphoma
189:primary effusion lymphoma
35:expression and unmutated
634:10.1182/blood.v99.7.2331
565:10.1182/blood.v97.7.2130
181:plasmablastic lymphoma
138:plasmablastic lymphoma
29:plasmablastic lymphoma
662:Int J Clin Exp Pathol
475:Non-Hodgkin Lymphomas
168:including the use of
119:organ transplantation
441:Rev Clin Exp Hematol
258:on October 12, 2013.
65:Human herpesvirus 8
19:is a type of large
741:Semin Diagn Pathol
111:immunodeficiencies
598:978-1-4511-7268-3
524:10.1002/ijc.28923
484:978-0-7817-9116-8
321:978-1-4377-2928-3
293:978-0-7216-0040-6
251:978-92-832-2431-0
162:antiviral therapy
75:cells within the
69:Castleman disease
48:Castleman disease
779:
757:
756:
735:
729:
728:
718:
694:
688:
687:
677:
653:
647:
646:
636:
612:
603:
602:
584:
578:
577:
567:
543:
537:
536:
526:
502:
489:
488:
470:
457:
456:
436:
427:
426:
397:
382:
381:
371:
339:
326:
325:
307:
298:
297:
279:
260:
259:
254:. Archived from
235:
204:Kaposi's sarcoma
146:cyclophosphamide
94:, most often of
787:
786:
782:
781:
780:
778:
777:
776:
762:
761:
760:
737:
736:
732:
703:Br. J. Haematol
696:
695:
691:
655:
654:
650:
614:
613:
606:
599:
586:
585:
581:
545:
544:
540:
504:
503:
492:
485:
472:
471:
460:
438:
437:
430:
399:
398:
385:
341:
340:
329:
322:
309:
308:
301:
294:
284:Hematopathology
281:
280:
263:
252:
237:
236:
232:
228:
216:
185:immunophenotype
45:
21:B-cell lymphoma
12:
11:
5:
785:
783:
775:
774:
764:
763:
759:
758:
730:
689:
648:
604:
597:
579:
538:
511:Int. J. Cancer
490:
483:
458:
447:(4): 375–405.
428:
409:(4): 1406–12.
383:
354:(2): 223–246.
327:
320:
299:
292:
261:
250:
229:
227:
224:
223:
222:
215:
212:
123:immunoglobulin
44:
41:
13:
10:
9:
6:
4:
3:
2:
784:
773:
770:
769:
767:
754:
750:
746:
742:
734:
731:
726:
722:
717:
712:
708:
704:
700:
693:
690:
685:
681:
676:
671:
668:(9): 6415–8.
667:
663:
659:
652:
649:
644:
640:
635:
630:
627:(7): 2331–6.
626:
622:
618:
611:
609:
605:
600:
594:
590:
583:
580:
575:
571:
566:
561:
558:(7): 2130–6.
557:
553:
549:
542:
539:
534:
530:
525:
520:
517:(2): 251–61.
516:
512:
508:
501:
499:
497:
495:
491:
486:
480:
476:
469:
467:
465:
463:
459:
454:
450:
446:
442:
435:
433:
429:
424:
420:
416:
412:
408:
404:
396:
394:
392:
390:
388:
384:
379:
375:
370:
365:
361:
357:
353:
349:
345:
338:
336:
334:
332:
328:
323:
317:
313:
306:
304:
300:
295:
289:
285:
278:
276:
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257:
253:
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243:
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234:
231:
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218:
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205:
200:
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194:
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186:
182:
177:
175:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
126:
124:
120:
116:
112:
108:
105:This type of
103:
101:
97:
93:
89:
85:
82:
78:
74:
70:
66:
62:
60:
57:
53:
49:
42:
40:
38:
34:
30:
26:
22:
18:
747:(1): 54–66.
744:
740:
733:
709:(1): 13–24.
706:
702:
692:
665:
661:
651:
624:
620:
588:
582:
555:
551:
541:
514:
510:
474:
444:
440:
406:
402:
351:
348:Semin. Oncol
347:
311:
283:
256:the original
240:
233:
201:
178:
142:chemotherapy
127:
113:, including
104:
63:
46:
24:
16:
15:
158:vincristine
150:doxorubicin
144:with CHOP (
130:lymph nodes
77:mantle zone
73:plasmablast
226:References
154:prednisone
50:(CD) is a
174:prognosis
170:rituximab
84:follicles
772:Lymphoma
766:Category
725:17991301
684:25337302
643:11895764
574:11264181
533:24771491
453:15129649
423:10666218
378:25843728
220:Lymphoma
214:See also
187:such as
132:and the
107:lymphoma
100:lymphoma
59:lymphoma
753:9044510
675:4203273
369:6309362
166:targets
43:Biology
39:genes.
751:
723:
682:
672:
641:
595:
572:
531:
481:
451:
421:
376:
366:
318:
290:
248:
195:, and
172:, the
134:spleen
96:lambda
81:B-cell
56:B-cell
621:Blood
552:Blood
403:Blood
749:PMID
721:PMID
680:PMID
639:PMID
593:ISBN
570:PMID
529:PMID
479:ISBN
449:PMID
419:PMID
374:PMID
316:ISBN
288:ISBN
246:ISBN
33:CD20
711:doi
707:140
670:PMC
629:doi
560:doi
519:doi
515:137
411:doi
364:PMC
356:doi
88:IgM
79:of
768::
745:14
743:.
719:.
705:.
701:.
678:.
664:.
660:.
637:.
625:99
623:.
619:.
607:^
568:.
556:97
554:.
550:.
527:.
513:.
509:.
493:^
461:^
443:.
431:^
417:.
407:95
405:.
386:^
372:.
362:.
352:42
350:.
346:.
330:^
302:^
264:^
199:.
191:,
156:,
152:,
148:,
102:.
61:.
755:.
727:.
713::
686:.
666:7
645:.
631::
601:.
576:.
562::
535:.
521::
487:.
455:.
445:7
425:.
413::
380:.
358::
324:.
296:.
90:-
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