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Libman–Sacks endocarditis

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is considered the primary evaluation for Libman–Sacks endocarditis; transesophageal echocardiography has greater sensitivity and specificity than transthoracic echocardiography. In case of a negative TTE in the presence of clinical signs of Libman–Sacks endocarditis, transesophageal echocardiography
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In systemic lupus erythematosus, Libman–Sacks endocarditis has been linked to pericarditis, presence of anticardiolipin antibodies, arterial and venous thromboses, and neuropsychiatric manifestations of systemic lupus erythematosus. Libman–Sacks endocarditis is associated with greater systemic lupus
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Libman–Sacks endocarditis vegetations are observed in 10% of systemic lupus erythematosus cases (however, in one study, vegetations were noted in 43% of systemic lupus erythematosus cases (0% in controls), and valvular thickening in 51% of systemic lupus erythematosus cases (7% in controls)). There
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The initial cause of Libman–Sacks endocarditis is poorly understood. It is thought to occur in the context of a hypercoagulable state which leads to endothelial injury and subsequent deposition of thrombi and inflammatory molecules in affected valves. The vegetations that are thus formed consist of
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Vegetations of the cardiac valves and endocardium are characterised by irregular borders, heterogenous echo density, and an absence of independent motion. Vegetations are usually small, but may be as large as 10mm. The basal and middle portions of the mitral and aortic valves are most commonly
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There is a paucity of empirical evidence on treatment options for persons with Libman–Sacks endocarditis, and treatment should focus on the underlying cause. Anticoagulant treatment is recommended in cases with previous thromboembolic event for prevention of subsequent occurrences. Surgical
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Libman–Sacks lesions rarely produce significant valve dysfunction and the lesions only rarely embolize. However, there is data to suggest an association between Libman–Sacks endocarditis and a higher risk for embolic cerebrovascular disease in people with systemic lupus erythematosus.
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is typically affected, and the vegetations occur on the ventricular and atrial surface of the valve. Though the left-sided heart valves (mitral and aortic) are most commonly affected, any heart valve as well as adjoining structures may become involved.
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secondary to dislodged vegetations. However, in some cases, severe valvular dysfunction may develop. People with systemic lupus erythematosus may present with other symptoms of the underlying diseases that give rise to Libman–Sacks endocarditis.
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Libman–Sacks endocarditis should be considered in instances of thromboembolism in persons with underlying pathology that is associated with LSE. Libman–Sacks endocarditis is diagnosed with echocardiography. Other potential etiologies (e.g.
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is a significant correlation between systemic lupus erythematosus duration and severity, and the incidence of Libman–Sacks endocarditis. Libman–Sacks endocarditis has been identified in 1.25% of those with malignant disease at autopsy.
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Differential diagnoses include: rheumatic valvular disease, atrial myxoma, degenerative valvular disease, infective endocarditis, vasculitis, cholesterol emboli syndrome, fibroelastoma, and Lambl's excrescences.
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erythematosus duration and severity. In some cases, Libman–Sacks endocarditis may be the presenting pathology in systemic lupus erythematosus, especially in the presence of concurrent antiphospholipid syndrome.
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Libman–Sacks endocarditis may result in arterial emboli, valvular insufficiency, and heart failure. Infective endocarditis occurs more frequently with those with systemic lupus erythematosus.
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The condition should be monitored to follow the development of the vegetations, and health personnel should be conscious of the potential risks associated with the condition.
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Hojnik Maja; George Jacob; Ziporen Lea; Shoenfeld Yehuda (1996-04-15). "Heart Valve Involvement (Libman-Sacks Endocarditis) in the Antiphospholipid Syndrome".
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Libman–Sacks endocarditis has been observed in 0.2% in of the general population at autopsy. It occurs most commonly in those aged 40 to 80 years.
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involved. Leaflet thickening or regurgitation may be present. There may be other cardiac pathology related to the underlying cause, e.g., lupus.
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Libman–Sacks endocarditis involves formation of cardiac lesions that may take the form of vegetations or thickening of the valvular leaflets.
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immune complexes, platelet thrombi, fibrin, and mononuclear cells. The vegetations may dislodge and cause embolisms.
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Libman–Sacks endocarditis itself is typically asymptomatic. Affected persons most commonly present with
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Doherty, N. E.; Siegel, R. J. (1985). "Cardiovascular manifestations of systemic lupus erythematosus".
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Libman, E.; Sacks, B. (1924). "A hitherto undescribed form of valvular and mural endocarditis".
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Libman–Sacks endocarditis is often associated with considerable morbidity and mortality.
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Vegetations occurring in the context of Libman–Sacks endocarditis may dislodge to form
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Nonbacterial thrombotic endocarditis, Marantic endocarditis, verrucous endocarditis
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intervention may be indicated in case of significant valvular dysfunction.
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in 1924. The association between Libman–Sacks endocarditis and
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may be attempted to confirm the presence of the condition.
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Mosby's Medical, Nursing & Allied Health Dictionary
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Libman–Sacks endocarditis occurs in association with
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Jr (2013). 350: 2121:Congenital contractural arachnodactyly 854:Spontaneous coronary artery dissection 534: 401: 399: 397: 395: 393: 391: 389: 218:are small and formed from strands of 7: 2149:Systemic connective tissue disorders 1178:Nonbacterial thrombotic endocarditis 614:10.1001/archinte.1924.00110300044002 556: 554: 552: 504: 502: 500: 498: 496: 494: 492: 490: 488: 436: 434: 387: 385: 383: 381: 379: 377: 375: 373: 371: 369: 1474:Accelerated idioventricular rhythm 25: 104:that is seen in association with 2038:Mixed connective tissue disease 1159:Subacute bacterial endocarditis 2014:Progressive systemic sclerosis 1: 2101:Eosinophilia–myalgia syndrome 1676:Pulseless electrical activity 1605:Multifocal atrial tachycardia 1479:Catecholaminergic polymorphic 601:Archives of Internal Medicine 513:(Ninth ed.). Edinburgh. 358:"Libman–Sacks endocarditis". 1930:Systemic lupus erythematosus 577:10.1016/0002-8703(85)90023-7 189:Systemic lupus erythematosus 175:systemic lupus erythematosus 106:systemic lupus erythematosus 68:Systemic lupus erythematosus 1915:connective tissue disorders 408:"Libman Sacks Endocarditis" 100:is a form of non-bacterial 2165: 1620:Wandering atrial pacemaker 1167:non-infective endocarditis 1108:Endocardial fibroelastosis 461:10.1016/j.jcmg.2013.04.012 321:It was first described by 159:transient ischaemic attack 2029: 1943:Libman–Sacks endocarditis 1698:hexaxial reference system 1643:Jervell and Lange-Nielsen 1173:Libman–Sacks endocarditis 414:, StatPearls Publishing, 341:was first noted in 1985. 339:antiphospholipid syndrome 179:antiphospholipid syndrome 110:antiphospholipid syndrome 98:Libman–Sacks endocarditis 78:Antiphospholipid syndrome 33:Libman–Sacks endocarditis 18:Libman-Sacks endocarditis 1980:Juvenile dermatomyositis 1578:Ventricular fibrillation 849:Coronary artery aneurysm 661:10.1161/01.CIR.93.8.1579 1989:Inclusion body myositis 1855:Diastolic heart failure 1829:Athletic heart syndrome 1790:Ventricular hypertrophy 1524:Pre-excitation syndrome 1378:Left posterior fascicle 903:Acute coronary syndrome 843:Coronary artery disease 2144:Valvular heart disease 2106:Ehlers–Danlos syndrome 2096:Eosinophilic fasciitis 2091:Polymyalgia rheumatica 1373:Left anterior fascicle 1153:infective endocarditis 938:Hibernating myocardium 819:Cardiovascular disease 564:American Heart Journal 448:Cardiovascular Imaging 276:Differential diagnosis 254:infective endocarditis 1958:Inflammatory myopathy 1537:Wolff–Parkinson–White 1497:Premature contraction 1395:Adams–Stokes syndrome 1098:Loeffler endocarditis 908:Myocardial infarction 2081:IgG4-related disease 2009:Systemic scleroderma 1704:Right axis deviation 1666:Sudden cardiac death 1024:Pericardial effusion 967:Ventricular aneurysm 331:Mount Sinai Hospital 285:Management/treatment 163:mesenteric ischaemia 1971:Dermatopolymyositis 1709:Left axis deviation 1566:Atrial fibrillation 1561:Ventricular flutter 1484:Torsades de pointes 1358:Bundle branch block 1317:Sick sinus syndrome 1103:Cardiac amyloidosis 1088:Tachycardia-induced 943:Myocardial stunning 891:Prinzmetal's angina 860:Coronary thrombosis 1812:Atrial enlargement 1610:Pacemaker syndrome 1532:Lown–Ganong–Levine 1454:Junctional ectopic 1449:AV nodal reentrant 955:Myocardial rupture 865:Coronary vasospasm 762:External resources 2131: 2130: 2046: 2045: 1880: 1879: 1872:Obstructive shock 1776: 1775: 1723:Short QT syndrome 1690:Other / ungrouped 1681:Sinoatrial arrest 1596:Ectopic pacemaker 1492: 1491: 1312:Sinus bradycardia 1284: 1283: 1280: 1279: 1029:Cardiac tamponade 982: 981: 972:Dressler syndrome 870:Myocardial bridge 785: 784: 520:978-0-323-55064-2 95: 94: 85:Diagnostic method 27:Medical condition 16:(Redirected from 2156: 2086:Behçet's disease 2065:Sjögren syndrome 2053:hypersensitivity 2034:Overlap syndrome 1938:Drug-induced SLE 1926: 1907: 1900: 1893: 1884: 1845:Cardiac fibrosis 1737:T wave alternans 1630:Long QT syndrome 1424:Supraventricular 1420: 1353:Intraventricular 1300: 1140: 991: 836:Coronary disease 833: 812: 805: 798: 789: 685: 673: 672: 655:(8): 1579–1587. 644: 638: 637: 635: 634: 624: 618: 617: 595: 589: 588: 571:(6): 1257–1265. 558: 547: 546: 540: 532: 506: 483: 482: 472: 438: 429: 428: 427: 426: 403: 364: 363: 355: 265:Echocardiography 260:Echocardiography 90:Echocardiography 30: 21: 2164: 2163: 2159: 2158: 2157: 2155: 2154: 2153: 2134: 2133: 2132: 2127: 2116:Marfan syndrome 2069: 2042: 2025: 1995: 1976:Dermatomyositis 1952: 1948:Lupus nephritis 1917: 1911: 1881: 1876: 1867:Rheumatic fever 1833: 1772: 1685: 1652: 1624: 1582: 1541: 1518: 1488: 1460: 1407: 1399: 1293: 1276: 1184: 1133: 1124: 1040: 1034:Hemopericardium 978: 919: 913:Unstable angina 886:Angina pectoris 879:Active ischemia 874: 822: 816: 786: 781: 780: 757: 756: 696: 682: 677: 676: 646: 645: 641: 632: 630: 626: 625: 621: 597: 596: 592: 560: 559: 550: 533: 521: 508: 507: 486: 440: 439: 432: 424: 422: 405: 404: 367: 357: 356: 352: 347: 319: 307: 299: 287: 278: 262: 249: 209: 200: 198:Pathophysiology 191: 171: 147: 139: 126: 76: 71: 28: 23: 22: 15: 12: 11: 5: 2162: 2160: 2152: 2151: 2146: 2136: 2135: 2129: 2128: 2126: 2125: 2124: 2123: 2118: 2108: 2103: 2098: 2093: 2088: 2083: 2077: 2075: 2071: 2070: 2068: 2067: 2061: 2059: 2048: 2047: 2044: 2043: 2041: 2040: 2030: 2027: 2026: 2024: 2023: 2022: 2021: 2019:CREST syndrome 2016: 2005: 2003: 1997: 1996: 1994: 1993: 1992: 1991: 1982: 1968: 1962: 1960: 1954: 1953: 1951: 1950: 1945: 1940: 1934: 1932: 1923: 1919: 1918: 1912: 1910: 1909: 1902: 1895: 1887: 1878: 1877: 1875: 1874: 1869: 1864: 1863: 1862: 1860:Cardiac asthma 1857: 1847: 1841: 1839: 1835: 1834: 1832: 1831: 1826: 1825: 1824: 1819: 1809: 1808: 1807: 1802: 1797: 1786: 1784: 1778: 1777: 1774: 1773: 1771: 1770: 1768:Strain pattern 1765: 1764: 1763: 1758: 1753: 1741: 1740: 1739: 1727: 1726: 1725: 1713: 1712: 1711: 1706: 1693: 1691: 1687: 1686: 1684: 1683: 1678: 1673: 1668: 1662: 1660: 1658:Cardiac arrest 1654: 1653: 1651: 1650: 1645: 1640: 1638:Andersen–Tawil 1634: 1632: 1626: 1625: 1623: 1622: 1617: 1612: 1607: 1602: 1592: 1590: 1584: 1583: 1581: 1580: 1575: 1574: 1573: 1563: 1558: 1556:Atrial flutter 1552: 1550: 1543: 1542: 1540: 1539: 1534: 1528: 1526: 1520: 1519: 1517: 1516: 1511: 1506: 1500: 1498: 1494: 1493: 1490: 1489: 1487: 1486: 1481: 1476: 1470: 1468: 1462: 1461: 1459: 1458: 1457: 1456: 1451: 1441: 1440: 1439: 1428: 1426: 1417: 1401: 1400: 1398: 1397: 1392: 1391: 1390: 1385: 1380: 1375: 1370: 1365: 1355: 1350: 1349: 1348: 1343: 1338: 1328: 1319: 1314: 1308: 1306: 1297: 1286: 1285: 1282: 1281: 1278: 1277: 1275: 1274: 1273: 1272: 1267: 1255: 1254: 1253: 1248: 1236: 1235: 1234: 1229: 1217: 1216: 1215: 1210: 1205: 1192: 1190: 1186: 1185: 1183: 1182: 1181: 1180: 1175: 1163: 1162: 1161: 1148: 1146: 1137: 1126: 1125: 1123: 1122: 1117: 1116: 1115: 1110: 1105: 1100: 1095: 1090: 1085: 1080: 1079: 1078: 1066:Cardiomyopathy 1063: 1062: 1061: 1059:Chagas disease 1050: 1048: 1042: 1041: 1039: 1038: 1037: 1036: 1031: 1021: 1020: 1019: 1010: 999: 997: 988: 984: 983: 980: 979: 977: 976: 975: 974: 969: 959: 958: 957: 947: 946: 945: 940: 929: 927: 921: 920: 918: 917: 916: 915: 910: 900: 899: 898: 893: 882: 880: 876: 875: 873: 872: 867: 862: 857: 851: 846: 839: 837: 830: 824: 823: 817: 815: 814: 807: 800: 792: 783: 782: 779: 778: 766: 765: 763: 759: 758: 755: 754: 743: 732: 717: 697: 692: 691: 689: 688:Classification 681: 680:External links 678: 675: 674: 639: 619: 608:(6): 701–737. 590: 548: 519: 484: 455:(9): 973–983. 430: 365: 349: 348: 346: 343: 327:Benjamin Sacks 323:Emanuel Libman 318: 315: 306: 303: 298: 295: 286: 283: 277: 274: 261: 258: 248: 245: 208: 207:Histopathology 205: 199: 196: 190: 187: 170: 167: 146: 143: 138: 135: 125: 122: 93: 92: 87: 81: 80: 65: 61: 60: 57: 51: 50: 41: 35: 34: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2161: 2150: 2147: 2145: 2142: 2141: 2139: 2122: 2119: 2117: 2114: 2113: 2112: 2109: 2107: 2104: 2102: 2099: 2097: 2094: 2092: 2089: 2087: 2084: 2082: 2079: 2078: 2076: 2072: 2066: 2063: 2062: 2060: 2058: 2054: 2049: 2039: 2035: 2032: 2031: 2028: 2020: 2017: 2015: 2012: 2011: 2010: 2007: 2006: 2004: 2002: 1998: 1990: 1986: 1983: 1981: 1977: 1974: 1973: 1972: 1969: 1967: 1964: 1963: 1961: 1959: 1955: 1949: 1946: 1944: 1941: 1939: 1936: 1935: 1933: 1931: 1927: 1924: 1920: 1916: 1908: 1903: 1901: 1896: 1894: 1889: 1888: 1885: 1873: 1870: 1868: 1865: 1861: 1858: 1856: 1853: 1852: 1851: 1850:Heart failure 1848: 1846: 1843: 1842: 1840: 1836: 1830: 1827: 1823: 1820: 1818: 1815: 1814: 1813: 1810: 1806: 1803: 1801: 1798: 1796: 1793: 1792: 1791: 1788: 1787: 1785: 1783: 1779: 1769: 1766: 1762: 1761:ST depression 1759: 1757: 1754: 1752: 1749: 1748: 1747: 1746: 1742: 1738: 1735: 1734: 1733: 1732: 1728: 1724: 1721: 1720: 1719: 1718: 1714: 1710: 1707: 1705: 1702: 1701: 1700: 1699: 1695: 1694: 1692: 1688: 1682: 1679: 1677: 1674: 1672: 1669: 1667: 1664: 1663: 1661: 1659: 1655: 1649: 1646: 1644: 1641: 1639: 1636: 1635: 1633: 1631: 1627: 1621: 1618: 1616: 1613: 1611: 1608: 1606: 1603: 1601: 1597: 1594: 1593: 1591: 1589: 1585: 1579: 1576: 1572: 1569: 1568: 1567: 1564: 1562: 1559: 1557: 1554: 1553: 1551: 1549: 1544: 1538: 1535: 1533: 1530: 1529: 1527: 1525: 1521: 1515: 1512: 1510: 1507: 1505: 1502: 1501: 1499: 1495: 1485: 1482: 1480: 1477: 1475: 1472: 1471: 1469: 1467: 1463: 1455: 1452: 1450: 1447: 1446: 1445: 1442: 1438: 1435: 1434: 1433: 1430: 1429: 1427: 1425: 1421: 1418: 1415: 1411: 1406: 1402: 1396: 1393: 1389: 1388:Trifascicular 1386: 1384: 1381: 1379: 1376: 1374: 1371: 1369: 1366: 1364: 1361: 1360: 1359: 1356: 1354: 1351: 1347: 1344: 1342: 1339: 1337: 1334: 1333: 1332: 1329: 1327: 1323: 1320: 1318: 1315: 1313: 1310: 1309: 1307: 1305: 1301: 1298: 1296: 1291: 1287: 1271: 1270:regurgitation 1268: 1266: 1263: 1262: 1261: 1260: 1256: 1252: 1251:regurgitation 1249: 1247: 1244: 1243: 1242: 1241: 1237: 1233: 1232:regurgitation 1230: 1228: 1225: 1224: 1223: 1222: 1218: 1214: 1213:regurgitation 1211: 1209: 1206: 1204: 1201: 1200: 1199: 1198: 1194: 1193: 1191: 1187: 1179: 1176: 1174: 1171: 1170: 1169: 1168: 1164: 1160: 1157: 1156: 1155: 1154: 1150: 1149: 1147: 1145: 1141: 1138: 1136: 1131: 1127: 1121: 1118: 1114: 1111: 1109: 1106: 1104: 1101: 1099: 1096: 1094: 1091: 1089: 1086: 1084: 1081: 1077: 1074: 1073: 1072: 1069: 1068: 1067: 1064: 1060: 1057: 1056: 1055: 1052: 1051: 1049: 1047: 1043: 1035: 1032: 1030: 1027: 1026: 1025: 1022: 1018: 1014: 1011: 1009: 1006: 1005: 1004: 1001: 1000: 998: 996: 992: 989: 985: 973: 970: 968: 965: 964: 963: 960: 956: 953: 952: 951: 948: 944: 941: 939: 936: 935: 934: 931: 930: 928: 926: 922: 914: 911: 909: 906: 905: 904: 901: 897: 896:Stable angina 894: 892: 889: 888: 887: 884: 883: 881: 877: 871: 868: 866: 863: 861: 858: 855: 852: 850: 847: 844: 841: 840: 838: 834: 831: 829: 825: 820: 813: 808: 806: 801: 799: 794: 793: 790: 777: 773: 772: 768: 767: 764: 760: 753: 749: 748: 744: 742: 738: 737: 733: 731: 727: 726: 722: 718: 716: 712: 708: 707: 703: 699: 698: 695: 690: 686: 679: 670: 666: 662: 658: 654: 650: 643: 640: 629: 623: 620: 615: 611: 607: 603: 602: 594: 591: 586: 582: 578: 574: 570: 566: 565: 557: 555: 553: 549: 544: 538: 530: 526: 522: 516: 512: 505: 503: 501: 499: 497: 495: 493: 491: 489: 485: 480: 476: 471: 466: 462: 458: 454: 450: 449: 444: 437: 435: 431: 421: 417: 413: 409: 402: 400: 398: 396: 394: 392: 390: 388: 386: 384: 382: 380: 378: 376: 374: 372: 370: 366: 361: 354: 351: 344: 342: 340: 336: 335:New York City 332: 328: 324: 316: 314: 310: 304: 302: 296: 294: 290: 284: 282: 275: 273: 269: 266: 259: 257: 255: 246: 244: 240: 237: 233: 229: 225: 221: 217: 212: 206: 204: 197: 195: 188: 186: 184: 180: 176: 168: 166: 164: 160: 156: 152: 144: 142: 137:Complications 136: 134: 131: 123: 121: 119: 115: 111: 107: 103: 99: 91: 88: 86: 82: 79: 74: 69: 66: 62: 58: 56: 52: 49: 45: 42: 40: 36: 31: 19: 1985:Polymyositis 1942: 1782:Cardiomegaly 1756:ST elevation 1743: 1729: 1715: 1696: 1600:Ectopic beat 1548:fibrillation 1383:Bifascicular 1257: 1238: 1219: 1195: 1172: 1165: 1151: 1144:Endocarditis 1083:Hypertrophic 1017:Constrictive 1003:Pericarditis 961: 949: 932: 769: 745: 734: 719: 700: 652: 648: 642: 631:. Retrieved 622: 605: 599: 593: 568: 562: 510: 452: 446: 423:, retrieved 411: 359: 353: 320: 311: 308: 305:Epidemiology 300: 291: 288: 279: 270: 263: 250: 241: 236:mitral valve 213: 210: 201: 192: 183:malignancies 172: 148: 140: 127: 124:Presentation 118:pericarditis 114:malignancies 102:endocarditis 97: 96: 44:Rheumatology 2001:Scleroderma 1648:Romano–Ward 1615:Parasystole 1514:Ventricular 1466:Ventricular 1405:Tachycardia 1322:Heart block 1304:Bradycardia 1130:Endocardium 1093:Restrictive 1054:Myocarditis 995:Pericardium 649:Circulation 232:histiocytes 228:lymphocytes 224:neutrophils 216:vegetations 2138:Categories 2057:autoimmune 1546:Flutter / 1509:Junctional 1444:Junctional 1437:Multifocal 1410:paroxysmal 1326:Sinoatrial 1295:arrhythmia 1290:Conduction 1046:Myocardium 747:DiseasesDB 633:2008-08-11 529:1051140253 425:2020-05-30 412:StatPearls 345:References 153:and cause 73:Malignancy 48:Cardiology 2111:fibrillin 1913:Systemic 1805:Pulmonary 1588:Pacemaker 1259:pulmonary 1240:tricuspid 1076:Alcoholic 771:eMedicine 537:cite book 297:Prognosis 247:Diagnosis 130:embolisms 39:Specialty 1966:Myositis 1671:Asystole 1571:Familial 1265:stenosis 1246:stenosis 1227:stenosis 1208:stenosis 1203:prolapse 925:Sequelae 828:Ischemia 776:med/1295 479:24029368 420:30422459 155:embolism 55:Symptoms 1922:General 1071:Dilated 1013:Chronic 821:(heart) 741:D008180 669:8608627 585:3907317 470:3941465 317:History 2051:Other 1751:J wave 1504:Atrial 1432:Atrial 1221:aortic 1197:mitral 1189:Valves 1135:valves 987:Layers 856:(SCAD) 667:  583:  527:  517:  477:  467:  418:  230:, and 220:fibrin 181:, and 169:Causes 151:emboli 145:Emboli 112:, and 64:Causes 2074:Other 1838:Other 1822:Right 1800:Right 1414:sinus 1363:Right 1113:Viral 1008:Acute 962:weeks 933:hours 845:(CAD) 752:29254 730:710.0 715:M32.1 1817:Left 1795:Left 1412:and 1368:Left 950:days 736:MeSH 725:9-CM 665:PMID 581:PMID 543:link 525:OCLC 515:ISBN 475:PMID 416:PMID 325:and 214:The 721:ICD 711:I39 702:ICD 657:doi 610:doi 573:doi 569:110 465:PMC 457:doi 333:in 329:at 161:), 120:). 2140:: 2036:/ 1987:* 1745:ST 1717:QT 1598:/ 1346:3° 1341:2° 1336:1° 1331:AV 1324:: 1015:/ 774:: 750:: 739:: 728:: 713:, 709:: 706:10 663:. 653:93 651:. 606:33 604:. 579:. 567:. 551:^ 539:}} 535:{{ 523:. 487:^ 473:. 463:. 451:. 445:. 433:^ 410:, 368:^ 226:, 222:, 185:. 177:, 108:, 46:, 2055:/ 1978:/ 1906:e 1899:t 1892:v 1731:T 1416:) 1408:( 1292:/ 1132:/ 811:e 804:t 797:v 723:- 704:- 694:D 671:. 659:: 636:. 616:. 612:: 587:. 575:: 545:) 531:. 481:. 459:: 453:6 75:, 70:, 20:)

Index

Libman-Sacks endocarditis
Specialty
Rheumatology
Cardiology
Symptoms
Systemic lupus erythematosus
Malignancy
Antiphospholipid syndrome
Diagnostic method
Echocardiography
endocarditis
systemic lupus erythematosus
antiphospholipid syndrome
malignancies
pericarditis
embolisms
emboli
embolism
transient ischaemic attack
mesenteric ischaemia
systemic lupus erythematosus
antiphospholipid syndrome
malignancies
vegetations
fibrin
neutrophils
lymphocytes
histiocytes
mitral valve
infective endocarditis

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