340:
174:
4135:
335:{\displaystyle {\begin{aligned}{\text{triglyceride}}+{\ce {H2O}}&\longrightarrow {\text{fatty acid}}+{\text{diacylglycerol}}\\{\text{diacylglycerol}}+{\ce {H2O}}&\longrightarrow {\text{fatty acid}}+{\text{monacylglycerol}}\\{\text{monacylglycerol}}+{\ce {H2O}}&\longrightarrow {\text{fatty acid}}+{\text{glycerol}}\end{aligned}}}
1021:
Lipases are catalysts for hydrolysis of esters and are useful outside of the cell, a testament to their wide substrate scope and ruggedness. The ester hydrolysis activity of lipases has been well evaluated for the conversion of triglycerides into biofuels or their precursors.
1917:
Gilbert B, Rouis M, Griglio S, de Lumley L, Laplaud P (2001). "Lipoprotein lipase (LPL) deficiency: a new patient homozygote for the preponderant mutation Gly188Glu in the human LPL gene and review of reported mutations: 75 % are clustered in exons 5 and 6".
1526:
Brady, L.; A. M. Brzozowski; Z. S. Derewenda; E. Dodson; G. Dodson; S. Tolley; J. P. Turkenburg; L. Christiansen; B. Huge-Jensen; L. Norskov; et al. (1990). "A serine protease triad forms the catalytic centre of a triacylglycerol lipase".
2405:
25. Gulzar, Bio-degradation of hydrocarbons using different bacterial and fungal species. Published in international conference on biotechnology and neurosciences. CUSAT (cochin university of science and technology), 2003
179:
1802:
Hube B, Stehr F, Bossenz M, Mazur A, Kretschmar M, Schafer W (2000). "Secreted lipases of
Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members".
1025:
Lipases are chiral, which means that they can be used for the enantioselective hydrolysis prochiral diesters. Several procedures have been reported for applications in the synthesis of fine chemicals.
3576:
1994:
De Caro J, Carriere F, Barboni P, Giller T, Verger R, De Caro A (1998). "Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species".
896:
of a single ancestral pancreatic lipase gene). However, PLRP1 is devoid of detectable lipase activity and its function remains unknown, even though it is conserved in other
467:
Fungi and bacteria may secrete lipases to facilitate nutrient absorption from the external medium (or in examples of pathogenic microbes, to promote invasion of a new host).
2119:
Harding, K.G; Dennis, J.S; von
Blottnitz, H; Harrison, S.T.L (2008). "A life-cycle comparison between inorganic and biological catalysis for the production of biodiesel".
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spaces where they serve to process dietary lipids into more simple forms that can be more easily absorbed and transported throughout the body.
4160:
1461:
1420:
1048:
2801:
1487:"A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig"
2216:
P. Kalaritis, R. W. Regenye (1990). "Enantiomerically Pure Ethyl (R)- And (S)- 2-Fluorohexanoate by Enzyme-Catalyzed
Kinetic Resolution".
3874:
2902:
2896:
2697:
2447:
1245:
Sharma, Rohit; Chisti, Yusuf; Banerjee, Uttam Chand (2001). "Production, purification, characterization, and applications of lipases".
2745:
20:
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2645:
2356:
Bustanji, Yasser; Al-Masri, Ihab M; Mohammad, Mohammad; Hudaib, Mohammad; Tawaha, Khaled; Tarazi, Hamada; Alkhatib, Hatim S (2010).
1018:
In the commercial sphere, lipases are widely used in laundry detergents. Several thousand tons per year are produced for this role.
664:
95:
2339:
348:, i.e. they function by transesterification generating an acyl serine intermediate. Most lipases act at a specific position on the
1082:
1072:
2963:
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1102:
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Pancreatic lipase related protein 1 is very similar to PLRP2 and PL by amino acid sequence (all three genes probably arose via
1763:"The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity"
2772:
2682:
2635:
3441:
2029:
Gupta R, Gupta N, Rathi P (2004). "Bacterial lipases: an overview of production, purification and biochemical properties".
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3831:
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3135:
753:
4125:
874:
848:
3239:
2806:
2796:
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Ban K, Kaieda M, Matsumoto T, Kondo A, Fukuda H (2001). "Whole cell biocatalyst for biodiesel fuel production utilizing
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739:
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Tjoelker LW; Eberhardt C; Unger J; Trong HL; Zimmerman GA; McIntyre TM; Stafforini DM; Prescott SM; PW Gray (1995).
4108:
2785:
2781:
2777:
2693:
2526:
2243:
Leo A. Paquette, Martyn J. Earle, Graham F. Smith (1996). "(4R)-(+)-tert-Butyldimethylsiloxy-2-cyclopenten-1-one".
1107:
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and other disorders of the pancreas. Measured serum lipase values may vary depending on the method of analysis.
380:
3436:
1444:
Egmond, M. R.; C. J. van Bemmel (1997). "Impact of structural information on understanding lipolytic function".
375:
A diverse array of genetically distinct lipase enzymes are found in nature, and they represent several types of
3809:
3390:
3333:
2701:
2550:
2464:
2419:
773:
2154:
Guo Z, Xu X (2005). "New opportunity for enzymatic modification of fats and oils with industrial potentials".
3804:
3672:
3637:
3338:
2570:
2440:
2335:"Anthera Pharmaceuticals – Sollpura." Anthera Pharmaceuticals – Sollpura. N.p., n.d. Web. 21 July 2015. <
698:
610:
457:
357:
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3924:
3762:
3724:
3126:
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1254:
1052:
1662:"Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad"
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493:
1129:
Lombardo, Dominique (2001). "Bile salt-dependent lipase: its pathophysiological implications".
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25:
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Crenon I, Foglizzo E, Kerfelec B, Verine A, Pignol D, Hermoso J, Bonicel J, Chapus C (1998).
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Lipases are involved in diverse biological processes which range from routine metabolism of
345:
140:
48:
661:
Also referred to as lysosomal acid lipase (LAL or LIPA) or acid cholesteryl ester hydrolase
4165:
4085:
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3421:
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Girod A, Wobus C, Zádori Z, Ried M, Leike K, Tijssen P, Kleinschmidt J, Hallek M (2002).
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908:
798:
676:
668:
434:
426:
23:
A computer-generated image of a type of pancreatic lipase (PLRP2) from the guinea pig.
2097:
2007:
1955:"Pancreatic lipase-related protein type I: a specialized lipase or an inactive enzyme"
1931:
1738:
1713:
1637:
1620:
1596:
1579:
1503:
1486:
1453:
1412:
1352:
Winkler FK; D'Arcy A; W Hunziker (1990). "Structure of human boob pancreatic lipase".
1268:
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2584:
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938:
785:
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461:
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407:
365:
3554:
2395:
2189:
Theil, Fritz (1995). "Lipase-Supported
Synthesis of Biologically Active Compounds".
1389:
1338:
1284:
143:; however, these are usually treated separately from "conventional" lipases. Unlike
4041:
4010:
3913:
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3313:
3052:
2983:
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1564:
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Active at gastric pH levels. Optimum pH is about 3.5-6. Secreted by several of the
486:
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384:
361:
132:
38:
2415:
2140:
1729:
2378:
2357:
1301:
Winkler FK; D'Arcy A; W Hunziker (1990). "Structure of human pancreatic lipase".
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3472:
3308:
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2892:
2755:
2721:
2659:
2425:
1700:
1580:"The catalytic site residues and interfacial binding of human pancreatic lipase"
1199:
Goñi F, Alonso A (2002). "Sphingomyelinases: enzymology and membrane activity".
835:
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688:
581:
395:
128:
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1971:
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Functions in the infant at a near-neutral pH to aid in the digestion of lipids
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446:
433:. Thus, some lipase activities are confined to specific compartments within
399:
152:
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2175:
2105:
2050:
1939:
1881:
1832:
1788:
1485:
Withers-Martinez C; Carriere F; Verger R; Bourgeois D; C Cambillau (1996).
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1185:
1150:
1028:
Lipases are generally animal sourced, but can also be sourced microbially.
2015:
1980:
1824:
1747:
1687:
1646:
1605:
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1471:
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1131:
Biochimica et
Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
523:
Some lipases are expressed and secreted by pathogenic organisms during an
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that enhance the effects of injury and inflammation delivered by a sting.
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108:
1036:
Blood tests for lipase may be used to help investigate and diagnose
671:
are both caused by mutations in the gene encoding lysosomal lipase.
537:
activity, which may contribute to the persistence and virulence of
3498:
3131:
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731:
694:
618:
517:
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18:
2358:"Pancreatic lipase inhibition activity of trilactone terpenes of
2863:
2740:
2733:
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2672:
1906:
Familial lipoprotein lipase deficiency – Genetics Home
Reference
761:
403:
3558:
3267:
2429:
171:
Classically, lipases catalyse the hydrolysis of triglycerides:
151:
to an oil–water interface". Lipases perform essential roles in
1044:
614:
120:
147:, which function in water, lipases "are activated only when
84:
78:
63:
57:
3263:
1712:
Afonso C, Tulman E, Lu Z, Oma E, Kutish G, Rock D (1999).
1448:. Methods in Enzymology. Vol. 284. pp. 119–129.
2284:"(4R)-(+)-tert-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE".
1407:. Methods in Enzymology. Vol. 284. pp. 85–107.
1403:
Schrag J, Cygler M (1997). "Lipases and hydrolase fold".
481:
are integral to living cells and are largely composed of
379:
and catalytic mechanisms. However, most are built on an
301:
251:
201:
697:
carried on lipoproteins in the blood to regenerate LDL (
628:
activity in the gut lumen, PL requires another protein,
123:. Some lipases display broad substrate scope including
4123:
2337:
http://www.anthera.com/pipeline/science/sollpura.html
2076:
cells immobilized within biomass support particles".
1621:"Signal transduction through lipid second messengers"
1164:
Diaz, B.L.; J. P. Arm. (2003). "Phospholipase A(2)".
177:
96:
87:
66:
2366:
Journal of Enzyme
Inhibition and Medicinal Chemistry
1714:"The Genome of Melanoplus sanguinipes Entomologists"
509:
and increase skin cell production, causing dandruff.
81:
75:
60:
54:
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2622:
2472:
72:
51:
613:(HPL) is the main enzyme that breaks down dietary
334:
2751:Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
16:Class of enzymes which cleave fats via hydrolysis
3570:
3279:
2441:
516:encoding lipases are even present in certain
8:
2269:: CS1 maint: multiple names: authors list (
533:has many lipases, possibly reflecting broad-
497:, a fungus thought to be the cause of human
1701:Genetic Code of Dandruff Cracked – BBC News
437:while others work in extracellular spaces.
4058:
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3577:
3563:
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3286:
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3264:
3057:
3003:
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2448:
2434:
2426:
1856:"The triglyceride lipases of the pancreas"
2418:at the U.S. National Library of Medicine
2377:
1970:
1871:
1778:
1737:
1677:
1636:
1619:Spiegel S; Foster D; R Kolesnick (1996).
1595:
1502:
1258:
632:, which is also secreted by the pancreas.
323:
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1240:
1238:
1166:Prostaglandins Leukot Essent Fatty Acids
548:
4130:
2641:Ubiquitin carboxy-terminal hydrolase L1
1118:
2262:
1296:
1294:
1124:
1122:
746:) so that cells can take up the freed
155:, transport and processing of dietary
3221:either deoxy- or ribo-
1049:pancreatic enzyme replacement therapy
693:Hepatic lipase acts on the remaining
364:substrates found in ingested oils to
7:
2802:Protein serine/threonine phosphatase
470:Certain wasp and bee venoms contain
3875:Glycogen phosphorylase isoenzyme BB
2903:Cyclic nucleotide phosphodiesterase
2897:Clostridium perfringens alpha toxin
2698:Tartrate-resistant acid phosphatase
875:pancreatic lipase related protein 1
849:pancreatic lipase related protein 2
445:, the enzyme is confined within an
387:-like hydrolysis mechanism using a
2746:Pyruvate dehydrogenase phosphatase
1043:Lipase assist in the breakdown of
485:, lipases play important roles in
14:
2646:4-hydroxybenzoyl-CoA thioesterase
665:Cholesteryl ester storage disease
167:Structure and catalytic mechanism
4133:
1073:Lysosomal acid lipase deficiency
47:
2964:N-acetylglucosamine-6-sulfatase
2852:Sphingomyelin phosphodiesterase
1625:Current Opinion in Cell Biology
1103:Outer membrane phospholipase A1
2773:Inositol-phosphate phosphatase
2636:Palmitoyl protein thioesterase
1446:Lipases, Part A: Biotechnology
1405:Lipases, Part A: Biotechnology
586:aids in the digestion of fats
456:Other lipase enzymes, such as
312:
262:
212:
1:
3832:Comprehensive metabolic panel
3136:RNA-induced silencing complex
2141:10.1016/j.jclepro.2007.07.003
2121:Journal of Cleaner Production
2098:10.1016/S1369-703X(00)00133-9
2008:10.1016/S0167-4838(98)00143-5
1932:10.1016/S0003-3995(01)01037-1
1730:10.1128/JVI.73.1.533-552.1999
1638:10.1016/S0955-0674(96)80061-5
1597:10.1016/S0021-9258(18)41893-5
1504:10.1016/S0969-2126(96)00143-8
1454:10.1016/S0076-6879(97)84008-6
1413:10.1016/S0076-6879(97)84006-2
1269:10.1016/S0734-9750(01)00086-6
1221:10.1016/S0014-5793(02)03482-8
1178:10.1016/S0952-3278(03)00069-3
1143:10.1016/S1388-1981(01)00130-5
1051:(PERT). It is a component in
754:Lipoprotein lipase deficiency
356:(A1, A2 or A3). For example,
4161:Peripheral membrane proteins
3240:Serratia marcescens nuclease
2807:Dual-specificity phosphatase
2797:Protein tyrosine phosphatase
2379:10.3109/14756366.2010.525509
1078:Peripheral membrane proteins
501:, uses lipase to break down
3768:Thyroid-stimulating hormone
3730:Total iron-binding capacity
2717:Fructose 1,6-bisphosphatase
4182:
4109:Elevated alpha-fetoprotein
1873:10.1194/jlr.R200012-JLR200
1780:10.1099/0022-1317-83-5-973
1108:Patatin-like phospholipase
570:bile salt-dependent lipase
414:Physiological distribution
3442:Michaelis–Menten kinetics
2954:Galactosamine-6 sulfatase
2510:6-phosphogluconolactonase
2043:10.1007/s00253-004-1568-8
2031:Appl Microbiol Biotechnol
381:alpha/beta hydrolase fold
3334:Diffusion-limited enzyme
2702:Purple acid phosphatases
2420:Medical Subject Headings
2298:10.15227/orgsyn.073.0036
2257:10.15227/orgsyn.073.0036
2230:10.15227/orgsyn.069.0010
1972:10.1093/protein/11.2.135
1679:10.1074/jbc.270.43.25481
774:hormone-sensitive lipase
107:) refers to a class of
3638:BUN-to-creatinine ratio
699:low density lipoprotein
611:Human pancreatic lipase
358:human pancreatic lipase
135:, and of lipid-soluble
4071:Elevated transaminases
3763:Thyroid function tests
3725:Transferrin saturation
3585:Clinical biochemistry
3127:Microprocessor complex
2766:Beta-propeller phytase
1247:Biotechnology Advances
1053:Sollpura (Liprotamase)
950:Other lipases include
336:
34:
3865:Lactate dehydrogenase
3827:Basic metabolic panel
3758:ACTH stimulation test
3427:Eadie–Hofstee diagram
3360:Allosteric regulation
3062:Endodeoxyribonuclease
2959:Iduronate-2-sulfatase
2712:Glucose 6-phosphatase
2498:Butyrylcholinesterase
1895:Omim – Wolman Disease
1825:10.1007/s002030000218
624:. To exhibit optimal
337:
159:in most, if not all,
22:
3885:Liver function tests
3740:Transferrin receptor
3437:Lineweaver–Burk plot
3245:Micrococcal nuclease
3080:Deoxyribonuclease IV
3075:Deoxyribonuclease II
3008:Exodeoxyribonuclease
2668:Alkaline phosphatase
2493:Acetylcholinesterase
1996:Biochim Biophys Acta
1047:in those undergoing
479:biological membranes
460:, are secreted into
352:backbone of a lipid
175:
3901:Serum total protein
3896:Human serum albumin
3100:UvrABC endonuclease
3070:Deoxyribonuclease I
2793:Protein phosphatase
2729:Protein phosphatase
2527:Bile salt-dependent
2515:PAF acetylhydrolase
2203:10.1021/cr00038a017
2133:2008JCPro..16.1368H
2090:2001BioEJ...8...39B
1817:2000ArMic.174..362H
1541:1990Natur.343..767B
1366:1990Natur.343..771W
1315:1990Natur.343..771W
1213:2002FEBSL.531...38G
1093:Triglyceride lipase
929:at the back of the
303:
253:
203:
3673:Arterial blood gas
3396:Enzyme superfamily
3329:Enzyme promiscuity
3233:Mung bean nuclease
3092:Restriction enzyme
3085:Restriction enzyme
2342:2015-07-18 at the
2312:"Lipase – TheTest"
1038:acute pancreatitis
824:endothelial lipase
766:lipoprotein lipase
742:(very low density
728:Lipoprotein lipase
710:lipoprotein lipase
651:interior space of
494:Malassezia globosa
458:pancreatic lipases
441:In the example of
332:
330:
291:
241:
191:
35:
4121:
4120:
4117:
4116:
4050:
4049:
4003:Blood sugar level
3982:Pancreatic lipase
3820:Total cholesterol
3650:Serum osmolal gap
3645:Plasma osmolality
3552:
3551:
3261:
3260:
3257:
3256:
3253:
3252:
3042:
3041:
3034:Oligonucleotidase
2979:deoxyribonuclease
2947:Steroid sulfatase
2822:Phosphodiesterase
2551:Hormone-sensitive
2286:Organic Syntheses
1463:978-0-12-182185-2
1422:978-0-12-182185-2
1360:(6260): 771–774.
1309:(6260): 771–774.
948:
947:
935:sublingual glands
736:triacylglycerides
730:functions in the
594:pancreatic lipase
541:in human tissue.
527:. In particular,
406:residue, usually
346:serine hydrolases
326:
318:
306:
294:
285:
276:
268:
256:
244:
235:
226:
218:
206:
194:
185:
141:sphingomyelinases
4173:
4138:
4137:
4129:
4093:Hyperproteinemia
4059:
3999:
3579:
3572:
3565:
3556:
3432:Hanes–Woolf plot
3375:Enzyme activator
3370:Enzyme inhibitor
3344:Enzyme catalysis
3288:
3281:
3274:
3265:
3110:Endoribonuclease
3096:
3090:
3058:
3004:
2990:
2690:Acid phosphatase
2571:Monoacylglycerol
2481:ester hydrolases
2450:
2443:
2436:
2427:
2400:
2399:
2381:
2353:
2347:
2333:
2327:
2326:
2324:
2322:
2316:Lab Tests Online
2308:
2302:
2301:
2281:
2275:
2274:
2268:
2260:
2240:
2234:
2233:
2213:
2207:
2206:
2197:(6): 2203–2227.
2191:Chemical Reviews
2186:
2180:
2179:
2168:10.1039/b506763d
2151:
2145:
2144:
2116:
2110:
2109:
2069:
2063:
2062:
2026:
2020:
2019:
1991:
1985:
1984:
1974:
1950:
1944:
1943:
1914:
1908:
1903:
1897:
1892:
1886:
1885:
1875:
1854:Lowe ME (2002).
1851:
1845:
1844:
1799:
1793:
1792:
1782:
1758:
1752:
1751:
1741:
1709:
1703:
1698:
1692:
1691:
1681:
1657:
1651:
1650:
1640:
1616:
1610:
1609:
1599:
1590:(24): 17069–73.
1578:Lowe ME (1992).
1575:
1569:
1568:
1549:10.1038/343767a0
1535:(6260): 767–70.
1523:
1517:
1516:
1506:
1482:
1476:
1475:
1441:
1435:
1434:
1400:
1394:
1393:
1374:10.1038/343771a0
1349:
1343:
1342:
1323:10.1038/343771a0
1298:
1289:
1288:
1262:
1242:
1233:
1232:
1196:
1190:
1189:
1161:
1155:
1154:
1126:
1098:Phospholipase A2
894:gene duplication
640:lysosomal lipase
622:digestive system
549:
530:Candida albicans
443:lysosomal lipase
391:consisting of a
360:(HPL), converts
341:
339:
338:
333:
331:
327:
324:
319:
316:
307:
304:
302:
299:
292:
286:
283:
277:
274:
269:
266:
257:
254:
252:
249:
242:
236:
233:
227:
224:
219:
216:
207:
204:
202:
199:
192:
186:
183:
103:
99:
94:
93:
90:
89:
86:
83:
80:
77:
74:
69:
68:
65:
62:
59:
56:
53:
32:
4181:
4180:
4176:
4175:
4174:
4172:
4171:
4170:
4146:
4145:
4144:
4132:
4124:
4122:
4113:
4097:
4086:Hypoalbuminemia
4081:Hypoproteinemia
4046:
4020:
3994:Small molecules
3988:
3958:
3879:
3836:
3774:
3744:
3701:
3691:
3654:
3589:
3583:
3553:
3548:
3460:Oxidoreductases
3446:
3422:Enzyme kinetics
3410:
3406:List of enzymes
3379:
3348:
3319:Catalytic triad
3297:
3292:
3262:
3249:
3216:
3104:
3094:
3088:
3051:
3038:
3026:Exoribonuclease
3020:
2997:
2981:
2977:
2968:
2942:Arylsulfatase L
2937:Arylsulfatase B
2932:Arylsulfatase A
2907:
2820:
2811:
2650:
2618:
2480:
2468:
2454:
2412:
2403:
2355:
2354:
2350:
2344:Wayback Machine
2334:
2330:
2320:
2318:
2310:
2309:
2305:
2283:
2282:
2278:
2261:
2242:
2241:
2237:
2215:
2214:
2210:
2188:
2187:
2183:
2156:Org Biomol Chem
2153:
2152:
2148:
2127:(13): 1368–78.
2118:
2117:
2113:
2074:Rhizopus oryzae
2071:
2070:
2066:
2028:
2027:
2023:
2002:(1–2): 331–41.
1993:
1992:
1988:
1952:
1951:
1947:
1916:
1915:
1911:
1904:
1900:
1893:
1889:
1866:(12): 2007–16.
1853:
1852:
1848:
1805:Arch. Microbiol
1801:
1800:
1796:
1773:(Pt 5): 973–8.
1760:
1759:
1755:
1711:
1710:
1706:
1699:
1695:
1672:(43): 25481–7.
1659:
1658:
1654:
1618:
1617:
1613:
1577:
1576:
1572:
1525:
1524:
1520:
1497:(11): 1363–74.
1484:
1483:
1479:
1464:
1443:
1442:
1438:
1423:
1402:
1401:
1397:
1351:
1350:
1346:
1300:
1299:
1292:
1260:10.1.1.319.7729
1244:
1243:
1236:
1198:
1197:
1193:
1163:
1162:
1158:
1128:
1127:
1120:
1116:
1088:Phospholipase C
1083:Phospholipase A
1061:
1034:
1016:
923:salivary glands
888:digestive juice
862:digestive juice
811:digestive juice
606:digestive juice
547:
416:
389:catalytic triad
329:
328:
308:
284:monacylglycerol
279:
278:
275:monacylglycerol
258:
229:
228:
208:
173:
172:
169:
101:
97:
71:
50:
46:
24:
17:
12:
11:
5:
4179:
4177:
4169:
4168:
4163:
4158:
4148:
4147:
4143:
4142:
4119:
4118:
4115:
4114:
4112:
4111:
4105:
4103:
4099:
4098:
4096:
4095:
4090:
4089:
4088:
4078:
4073:
4067:
4065:
4056:
4052:
4051:
4048:
4047:
4045:
4044:
4039:
4034:
4028:
4026:
4022:
4021:
4019:
4018:
4013:
4007:
4005:
3996:
3990:
3989:
3987:
3986:
3985:
3984:
3974:
3968:
3966:
3960:
3959:
3957:
3956:
3955:
3954:
3949:
3939:
3934:
3933:
3932:
3927:
3922:
3910:
3905:
3904:
3903:
3898:
3889:
3887:
3881:
3880:
3878:
3877:
3872:
3867:
3862:
3857:
3852:
3850:Cardiac marker
3846:
3844:
3842:Cardiovascular
3838:
3837:
3835:
3834:
3829:
3824:
3823:
3822:
3817:
3812:
3807:
3797:
3796:
3795:
3793:Hemoglobin A1c
3784:
3782:
3776:
3775:
3773:
3772:
3771:
3770:
3760:
3754:
3752:
3746:
3745:
3743:
3742:
3737:
3732:
3727:
3722:
3717:
3711:
3709:
3703:
3702:
3700:
3699:
3694:
3689:
3685:
3680:
3675:
3670:
3664:
3662:
3656:
3655:
3653:
3652:
3647:
3642:
3641:
3640:
3635:
3630:
3623:Renal function
3620:
3615:
3610:
3605:
3599:
3597:
3591:
3590:
3584:
3582:
3581:
3574:
3567:
3559:
3550:
3549:
3547:
3546:
3533:
3520:
3507:
3494:
3481:
3468:
3454:
3452:
3448:
3447:
3445:
3444:
3439:
3434:
3429:
3424:
3418:
3416:
3412:
3411:
3409:
3408:
3403:
3398:
3393:
3387:
3385:
3384:Classification
3381:
3380:
3378:
3377:
3372:
3367:
3362:
3356:
3354:
3350:
3349:
3347:
3346:
3341:
3336:
3331:
3326:
3321:
3316:
3311:
3305:
3303:
3299:
3298:
3293:
3291:
3290:
3283:
3276:
3268:
3259:
3258:
3255:
3254:
3251:
3250:
3248:
3247:
3242:
3237:
3236:
3235:
3224:
3222:
3218:
3217:
3215:
3214:
3209:
3208:
3207:
3202:
3197:
3192:
3182:
3177:
3172:
3167:
3166:
3165:
3160:
3155:
3150:
3140:
3139:
3138:
3129:
3114:
3112:
3106:
3105:
3103:
3102:
3097:
3082:
3077:
3072:
3066:
3064:
3055:
3044:
3043:
3040:
3039:
3037:
3036:
3030:
3028:
3022:
3021:
3019:
3018:
3012:
3010:
3001:
2987:
2970:
2969:
2967:
2966:
2961:
2956:
2951:
2950:
2949:
2944:
2939:
2934:
2921:
2919:
2909:
2908:
2906:
2905:
2900:
2890:
2885:
2876:
2871:
2866:
2861:
2860:
2859:
2849:
2848:
2847:
2842:
2832:
2826:
2824:
2813:
2812:
2810:
2809:
2804:
2799:
2790:
2789:
2788:
2770:
2769:
2768:
2758:
2753:
2748:
2743:
2738:
2737:
2736:
2726:
2725:
2724:
2714:
2709:
2704:
2687:
2686:
2685:
2680:
2675:
2664:
2662:
2652:
2651:
2649:
2648:
2643:
2638:
2632:
2630:
2620:
2619:
2617:
2616:
2611:
2605:
2604:
2603:
2602:
2597:
2592:
2581:
2580:
2579:
2578:
2576:Diacylglycerol
2573:
2568:
2563:
2558:
2553:
2548:
2543:
2538:
2529:
2518:
2517:
2512:
2507:
2505:Pectinesterase
2502:
2501:
2500:
2495:
2488:Cholinesterase
2484:
2482:
2470:
2469:
2455:
2453:
2452:
2445:
2438:
2430:
2424:
2423:
2411:
2410:External links
2408:
2402:
2401:
2348:
2328:
2303:
2276:
2235:
2208:
2181:
2162:(14): 2615–9.
2146:
2111:
2064:
2021:
1986:
1945:
1909:
1898:
1887:
1846:
1811:(5): 362–374.
1794:
1753:
1704:
1693:
1652:
1611:
1570:
1518:
1477:
1462:
1436:
1421:
1395:
1344:
1290:
1253:(8): 627–662.
1234:
1191:
1172:(2–3): 87–97.
1156:
1117:
1115:
1112:
1111:
1110:
1105:
1100:
1095:
1090:
1085:
1080:
1075:
1070:
1067:
1060:
1057:
1033:
1030:
1015:
1012:
946:
945:
942:
939:parotid glands
933:(lingua), the
927:Ebner's glands
919:
914:
911:
909:lingual lipase
905:
904:
901:
890:
885:
877:
871:
870:
867:
864:
859:
851:
845:
844:
841:
838:
833:
826:
820:
819:
816:
813:
808:
801:
799:gastric lipase
795:
794:
791:
788:
783:
776:
770:
769:
751:
725:
720:
712:
706:
705:
702:
691:
686:
679:
677:hepatic lipase
673:
672:
669:Wolman disease
662:
659:
649:
642:
636:
635:
633:
608:
603:
596:
590:
589:
587:
584:
575:
572:
566:
565:
562:
559:
556:
553:
546:
543:
511:
510:
490:
475:
472:phospholipases
468:
465:
454:
427:cell signaling
415:
412:
366:monoglycerides
322:
314:
311:
309:
298:
289:
281:
280:
272:
264:
261:
259:
248:
239:
234:diacylglycerol
231:
230:
225:diacylglycerol
222:
214:
211:
209:
198:
189:
181:
180:
168:
165:
15:
13:
10:
9:
6:
4:
3:
2:
4178:
4167:
4164:
4162:
4159:
4157:
4154:
4153:
4151:
4141:
4136:
4131:
4127:
4110:
4107:
4106:
4104:
4100:
4094:
4091:
4087:
4084:
4083:
4082:
4079:
4077:
4074:
4072:
4069:
4068:
4066:
4064:
4060:
4057:
4053:
4043:
4040:
4038:
4037:Hyperuricemia
4035:
4033:
4030:
4029:
4027:
4023:
4017:
4016:Hyperglycemia
4014:
4012:
4009:
4008:
4006:
4004:
4000:
3997:
3995:
3991:
3983:
3980:
3979:
3978:
3975:
3973:
3970:
3969:
3967:
3965:
3961:
3953:
3950:
3948:
3945:
3944:
3943:
3940:
3938:
3935:
3931:
3930:AST/ALT ratio
3928:
3926:
3923:
3921:
3918:
3917:
3916:
3915:
3914:transaminases
3911:
3909:
3906:
3902:
3899:
3897:
3894:
3893:
3891:
3890:
3888:
3886:
3882:
3876:
3873:
3871:
3868:
3866:
3863:
3861:
3858:
3856:
3855:Troponin test
3853:
3851:
3848:
3847:
3845:
3843:
3839:
3833:
3830:
3828:
3825:
3821:
3818:
3816:
3815:Triglycerides
3813:
3811:
3808:
3806:
3803:
3802:
3801:
3798:
3794:
3791:
3790:
3789:
3788:Blood glucose
3786:
3785:
3783:
3781:
3777:
3769:
3766:
3765:
3764:
3761:
3759:
3756:
3755:
3753:
3751:
3747:
3741:
3738:
3736:
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3712:
3710:
3708:
3704:
3698:
3695:
3693:
3686:
3684:
3681:
3679:
3676:
3674:
3671:
3669:
3666:
3665:
3663:
3661:
3657:
3651:
3648:
3646:
3643:
3639:
3636:
3634:
3631:
3629:
3626:
3625:
3624:
3621:
3619:
3616:
3614:
3611:
3609:
3606:
3604:
3601:
3600:
3598:
3596:
3592:
3588:
3580:
3575:
3573:
3568:
3566:
3561:
3560:
3557:
3544:
3540:
3539:
3534:
3531:
3527:
3526:
3521:
3518:
3514:
3513:
3508:
3505:
3501:
3500:
3495:
3492:
3488:
3487:
3482:
3479:
3475:
3474:
3469:
3466:
3462:
3461:
3456:
3455:
3453:
3449:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3419:
3417:
3413:
3407:
3404:
3402:
3401:Enzyme family
3399:
3397:
3394:
3392:
3389:
3388:
3386:
3382:
3376:
3373:
3371:
3368:
3366:
3365:Cooperativity
3363:
3361:
3358:
3357:
3355:
3351:
3345:
3342:
3340:
3337:
3335:
3332:
3330:
3327:
3325:
3324:Oxyanion hole
3322:
3320:
3317:
3315:
3312:
3310:
3307:
3306:
3304:
3300:
3296:
3289:
3284:
3282:
3277:
3275:
3270:
3269:
3266:
3246:
3243:
3241:
3238:
3234:
3231:
3230:
3229:
3226:
3225:
3223:
3219:
3213:
3210:
3206:
3203:
3201:
3198:
3196:
3193:
3191:
3188:
3187:
3186:
3183:
3181:
3178:
3176:
3173:
3171:
3168:
3164:
3161:
3159:
3156:
3154:
3151:
3149:
3146:
3145:
3144:
3141:
3137:
3133:
3130:
3128:
3124:
3121:
3120:
3119:
3116:
3115:
3113:
3111:
3107:
3101:
3098:
3093:
3086:
3083:
3081:
3078:
3076:
3073:
3071:
3068:
3067:
3065:
3063:
3059:
3056:
3054:
3049:
3045:
3035:
3032:
3031:
3029:
3027:
3023:
3017:
3014:
3013:
3011:
3009:
3005:
3002:
3000:
2995:
2991:
2988:
2985:
2980:
2975:
2971:
2965:
2962:
2960:
2957:
2955:
2952:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2929:
2928:
2927:
2926:arylsulfatase
2923:
2922:
2920:
2918:
2914:
2910:
2904:
2901:
2898:
2894:
2891:
2889:
2886:
2884:
2880:
2877:
2875:
2872:
2870:
2867:
2865:
2862:
2858:
2855:
2854:
2853:
2850:
2846:
2843:
2841:
2838:
2837:
2836:
2835:Phospholipase
2833:
2831:
2828:
2827:
2825:
2823:
2818:
2814:
2808:
2805:
2803:
2800:
2798:
2794:
2791:
2787:
2783:
2779:
2776:
2775:
2774:
2771:
2767:
2764:
2763:
2762:
2759:
2757:
2754:
2752:
2749:
2747:
2744:
2742:
2739:
2735:
2732:
2731:
2730:
2727:
2723:
2720:
2719:
2718:
2715:
2713:
2710:
2708:
2705:
2703:
2699:
2695:
2691:
2688:
2684:
2681:
2679:
2676:
2674:
2671:
2670:
2669:
2666:
2665:
2663:
2661:
2657:
2653:
2647:
2644:
2642:
2639:
2637:
2634:
2633:
2631:
2629:
2625:
2621:
2615:
2612:
2610:
2607:
2606:
2601:
2598:
2596:
2593:
2591:
2588:
2587:
2586:
2585:Phospholipase
2583:
2582:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2557:
2554:
2552:
2549:
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2542:
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2533:
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2516:
2513:
2511:
2508:
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2503:
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2475:
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2439:
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2421:
2417:
2414:
2413:
2409:
2407:
2397:
2393:
2389:
2385:
2380:
2375:
2371:
2367:
2363:
2361:
2360:Ginkgo biloba
2352:
2349:
2345:
2341:
2338:
2332:
2329:
2317:
2313:
2307:
2304:
2299:
2295:
2291:
2287:
2280:
2277:
2272:
2266:
2258:
2254:
2250:
2246:
2239:
2236:
2231:
2227:
2223:
2219:
2212:
2209:
2204:
2200:
2196:
2192:
2185:
2182:
2177:
2173:
2169:
2165:
2161:
2157:
2150:
2147:
2142:
2138:
2134:
2130:
2126:
2122:
2115:
2112:
2107:
2103:
2099:
2095:
2091:
2087:
2083:
2079:
2078:Biochem Eng J
2075:
2068:
2065:
2060:
2056:
2052:
2048:
2044:
2040:
2037:(6): 763–81.
2036:
2032:
2025:
2022:
2017:
2013:
2009:
2005:
2001:
1997:
1990:
1987:
1982:
1978:
1973:
1968:
1965:(2): 135–42.
1964:
1960:
1956:
1949:
1946:
1941:
1937:
1933:
1929:
1925:
1921:
1913:
1910:
1907:
1902:
1899:
1896:
1891:
1888:
1883:
1879:
1874:
1869:
1865:
1861:
1857:
1850:
1847:
1842:
1838:
1834:
1830:
1826:
1822:
1818:
1814:
1810:
1806:
1798:
1795:
1790:
1786:
1781:
1776:
1772:
1768:
1764:
1757:
1754:
1749:
1745:
1740:
1735:
1731:
1727:
1724:(1): 533–52.
1723:
1719:
1715:
1708:
1705:
1702:
1697:
1694:
1689:
1685:
1680:
1675:
1671:
1667:
1663:
1656:
1653:
1648:
1644:
1639:
1634:
1631:(2): 159–67.
1630:
1626:
1622:
1615:
1612:
1607:
1603:
1598:
1593:
1589:
1585:
1581:
1574:
1571:
1566:
1562:
1558:
1554:
1550:
1546:
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1534:
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1514:
1510:
1505:
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1496:
1492:
1488:
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1478:
1473:
1469:
1465:
1459:
1455:
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1447:
1440:
1437:
1432:
1428:
1424:
1418:
1414:
1410:
1406:
1399:
1396:
1391:
1387:
1383:
1379:
1375:
1371:
1367:
1363:
1359:
1355:
1348:
1345:
1340:
1336:
1332:
1328:
1324:
1320:
1316:
1312:
1308:
1304:
1297:
1295:
1291:
1286:
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1278:
1274:
1270:
1266:
1261:
1256:
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1239:
1235:
1230:
1226:
1222:
1218:
1214:
1210:
1206:
1202:
1195:
1192:
1187:
1183:
1179:
1175:
1171:
1167:
1160:
1157:
1152:
1148:
1144:
1140:
1136:
1132:
1125:
1123:
1119:
1113:
1109:
1106:
1104:
1101:
1099:
1096:
1094:
1091:
1089:
1086:
1084:
1081:
1079:
1076:
1074:
1071:
1068:
1066:
1063:
1062:
1058:
1056:
1054:
1050:
1046:
1041:
1039:
1031:
1029:
1026:
1023:
1019:
1013:
1011:
1009:
1008:
1003:
1002:
997:
996:
991:
990:
985:
984:
979:
978:
973:
972:
967:
966:
961:
960:
955:
954:
943:
940:
936:
932:
928:
924:
920:
918:
915:
912:
910:
907:
906:
902:
899:
895:
891:
889:
886:
883:
882:
878:
876:
873:
872:
868:
865:
863:
860:
857:
856:
852:
850:
847:
846:
842:
839:
837:
834:
832:
831:
827:
825:
822:
821:
817:
814:
812:
809:
807:
806:
802:
800:
797:
796:
792:
789:
787:
786:intracellular
784:
782:
781:
777:
775:
772:
771:
767:
763:
759:
756:is caused by
755:
752:
749:
745:
741:
737:
733:
729:
726:
724:
721:
718:
717:
713:
711:
708:
707:
703:
700:
696:
692:
690:
687:
685:
684:
680:
678:
675:
674:
670:
666:
663:
660:
658:
654:
650:
648:
647:
643:
641:
638:
637:
634:
631:
627:
623:
620:
616:
612:
609:
607:
604:
602:
601:
597:
595:
592:
591:
588:
585:
583:
579:
576:
573:
571:
568:
567:
563:
560:
557:
554:
551:
550:
545:Human lipases
544:
542:
540:
536:
532:
531:
526:
521:
519:
515:
508:
504:
500:
496:
495:
491:
488:
484:
483:phospholipids
480:
476:
473:
469:
466:
463:
462:extracellular
459:
455:
452:
448:
444:
440:
439:
438:
436:
432:
428:
424:
423:triglycerides
421:
413:
411:
409:
408:aspartic acid
405:
402:base, and an
401:
397:
394:
390:
386:
383:and employ a
382:
378:
377:protein folds
373:
371:
367:
363:
359:
355:
351:
347:
342:
320:
310:
296:
287:
270:
260:
246:
237:
220:
210:
196:
187:
166:
164:
162:
158:
154:
150:
146:
142:
138:
134:
133:phospholipids
130:
126:
122:
118:
114:
110:
106:
105:
92:
44:
40:
31:
27:
21:
4076:Elevated ALP
4042:Hypouricemia
4011:Hypoglycemia
3976:
3947:Unconjugated
3912:
3595:Electrolytes
3538:Translocases
3535:
3522:
3509:
3496:
3483:
3473:Transferases
3470:
3457:
3314:Binding site
3095:}}
3089:{{
3053:Endonuclease
2984:ribonuclease
2924:
2707:Nucleotidase
2628:Thioesterase
2521:
2404:
2372:(4): 453–9.
2369:
2365:
2359:
2351:
2331:
2319:. Retrieved
2315:
2306:
2292:: 36. 1996.
2289:
2285:
2279:
2265:cite journal
2248:
2244:
2238:
2221:
2217:
2211:
2194:
2190:
2184:
2159:
2155:
2149:
2124:
2120:
2114:
2084:(1): 39–43.
2081:
2077:
2073:
2067:
2034:
2030:
2024:
1999:
1995:
1989:
1962:
1958:
1948:
1926:(1): 25–32.
1923:
1919:
1912:
1901:
1890:
1863:
1859:
1849:
1808:
1804:
1797:
1770:
1766:
1756:
1721:
1717:
1707:
1696:
1669:
1665:
1655:
1628:
1624:
1614:
1587:
1583:
1573:
1532:
1528:
1521:
1494:
1490:
1480:
1445:
1439:
1404:
1398:
1357:
1353:
1347:
1306:
1302:
1250:
1246:
1207:(1): 38–46.
1204:
1200:
1194:
1169:
1165:
1159:
1134:
1130:
1042:
1035:
1027:
1024:
1020:
1017:
1005:
999:
993:
987:
981:
975:
969:
963:
957:
951:
949:
879:
858:or "PLRP2" –
853:
828:
803:
778:
714:
681:
644:
598:
539:C. albicans
538:
528:
522:
512:
492:
487:cell biology
431:inflammation
417:
385:chymotrypsin
374:
362:triglyceride
344:Lipases are
343:
184:triglyceride
170:
42:
39:biochemistry
36:
4025:Nitrogenous
3860:CPK-MB test
3800:Lipid panel
3735:Transferrin
3683:Bicarbonate
3678:Base excess
3587:blood tests
3309:Active site
3228:Nuclease S1
2999:Exonuclease
2893:Lecithinase
2722:Calcineurin
2660:Phosphatase
2566:Lipoprotein
2556:Endothelial
1959:Protein Eng
1860:J Lipid Res
1767:J Gen Virol
1666:J Biol Chem
1584:J Biol Chem
1137:(1): 1–28.
1065:Alpha toxin
1032:Biomedicine
836:endothelium
748:fatty acids
744:lipoprotein
738:carried on
723:endothelium
689:endothelium
667:(CESD) and
582:breast milk
561:Description
449:called the
396:nucleophile
370:fatty acids
129:cholesterol
4156:Hydrolases
4150:Categories
3952:Conjugated
3780:Metabolism
3720:Serum iron
3707:Iron tests
3628:Creatinine
3512:Isomerases
3486:Hydrolases
3353:Regulation
2541:Pancreatic
2478:Carboxylic
2245:Org. Synth
2218:Org. Synth
1114:References
937:, and the
884:or "PLRP1"
764:encoding
734:to act on
507:oleic acid
317:fatty acid
267:fatty acid
217:fatty acid
117:hydrolysis
3942:Bilirubin
3892:Proteins
3870:Myoglobin
3668:Anion gap
3660:Acid-base
3608:Potassium
3391:EC number
3118:RNase III
2976:(includes
2917:Sulfatase
2830:Autotaxin
2694:Prostatic
2546:Lysosomal
2461:esterases
2457:Hydrolase
2059:206934353
1920:Ann Genet
1491:Structure
1255:CiteSeerX
1201:FEBS Lett
1069:Pathology
758:mutations
719:or "LIPD"
653:organelle
564:Disorder
535:lipolytic
525:infection
447:organelle
400:histidine
354:substrate
313:⟶
263:⟶
213:⟶
161:organisms
153:digestion
145:esterases
113:catalyzes
4055:Proteins
4032:Azotemia
3964:Pancreas
3750:Hormones
3715:Ferritin
3613:Chloride
3415:Kinetics
3339:Cofactor
3302:Activity
3212:RNase T1
2974:Nuclease
2609:Cutinase
2396:23597738
2388:21028941
2340:Archived
2176:15999195
2106:11356369
2051:14966663
1940:11334614
1882:12454260
1833:11131027
1789:11961250
1390:37423900
1339:37423900
1285:18615547
1277:14550014
1229:12401200
1186:12895591
1151:11514232
1059:See also
881:PNLIPRP1
855:PNLIPRP2
657:lysosome
630:colipase
578:pancreas
558:Location
499:dandruff
451:lysosome
368:and two
350:glycerol
325:glycerol
149:adsorbed
137:vitamins
100:-payss,
33:.
4140:Biology
3972:Amylase
3697:Lactate
3692:content
3618:Calcium
3525:Ligases
3295:Enzymes
3185:RNase E
3180:RNase Z
3175:RNase A
3170:RNase P
3143:RNase H
2761:Phytase
2561:Hepatic
2536:Lingual
2532:Gastric
2129:Bibcode
2086:Bibcode
2016:9748646
1981:9605548
1841:2231039
1813:Bibcode
1748:9847359
1718:J Virol
1688:7592717
1647:8791422
1606:1512245
1565:4308111
1557:2304552
1537:Bibcode
1513:8939760
1472:9379930
1431:9379946
1382:2106079
1362:Bibcode
1331:2106079
1311:Bibcode
1209:Bibcode
898:mammals
760:in the
617:in the
518:viruses
420:dietary
109:enzymes
4166:EC 3.1
4126:Portal
3977:Lipase
3603:Sodium
3499:Lyases
3123:Drosha
3048:3.1.21
3016:RecBCD
2994:3.1.11
2614:PETase
2522:Lipase
2422:(MeSH)
2416:Lipase
2394:
2386:
2321:12 May
2251:: 36.
2224:: 10.
2174:
2104:
2057:
2049:
2014:
1979:
1938:
1880:
1839:
1831:
1787:
1746:
1739:103860
1736:
1686:
1645:
1604:
1563:
1555:
1529:Nature
1511:
1470:
1460:
1429:
1419:
1388:
1380:
1354:Nature
1337:
1329:
1303:Nature
1283:
1275:
1257:
1227:
1184:
1149:
1004:, and
931:tongue
917:saliva
695:lipids
626:enzyme
393:serine
157:lipids
125:esters
43:lipase
4102:Other
3451:Types
3132:Dicer
3087:;see
2913:3.1.6
2883:PDE4B
2879:PDE4A
2817:3.1.4
2786:IMPA3
2782:IMPA2
2778:IMPA1
2656:3.1.3
2624:3.1.2
2474:3.1.1
2392:S2CID
2346:>.
2055:S2CID
1837:S2CID
1561:S2CID
1386:S2CID
1335:S2CID
1281:S2CID
1001:DAGLB
995:DAGLA
732:blood
619:human
600:PNLIP
514:Genes
505:into
503:sebum
435:cells
111:that
104:-payz
3633:Urea
3543:list
3536:EC7
3530:list
3523:EC6
3517:list
3510:EC5
3504:list
3497:EC4
3491:list
3484:EC3
3478:list
3471:EC2
3465:list
3458:EC1
3050:-31:
2996:-16:
2982:and
2888:PDE5
2874:PDE3
2869:PDE2
2864:PDE1
2756:PTEN
2741:OCRL
2734:PP2A
2683:ALPP
2678:ALPL
2673:ALPI
2467:3.1)
2384:PMID
2323:2014
2271:link
2172:PMID
2102:PMID
2047:PMID
2012:PMID
2000:1387
1977:PMID
1936:PMID
1878:PMID
1829:PMID
1785:PMID
1744:PMID
1684:PMID
1643:PMID
1602:PMID
1553:PMID
1509:PMID
1468:PMID
1458:ISBN
1427:PMID
1417:ISBN
1378:PMID
1327:PMID
1273:PMID
1225:PMID
1182:PMID
1147:PMID
1135:1533
1045:fats
1014:Uses
989:MGLL
983:LIPN
977:LIPM
971:LIPK
965:LIPJ
959:LIPI
953:LIPH
830:LIPG
805:LIPF
780:LIPE
762:gene
740:VLDL
683:LIPC
646:LIPA
615:fats
574:BSDL
555:Gene
552:Name
429:and
404:acid
398:, a
139:and
121:fats
115:the
30:1GPL
4063:LFT
3937:GGT
3925:AST
3920:ALT
3908:ALP
3810:HDL
3805:LDL
3205:4/5
2374:doi
2294:doi
2253:doi
2226:doi
2199:doi
2164:doi
2137:doi
2094:doi
2039:doi
2004:doi
1967:doi
1928:doi
1868:doi
1821:doi
1809:174
1775:doi
1734:PMC
1726:doi
1674:doi
1670:270
1633:doi
1592:doi
1588:267
1545:doi
1533:343
1499:doi
1450:doi
1409:doi
1370:doi
1358:343
1319:doi
1307:343
1265:doi
1217:doi
1205:531
1174:doi
1139:doi
1007:CEL
716:LPL
477:As
425:to
127:of
119:of
37:In
26:PDB
4152::
3688:CO
3163:2C
3158:2B
3153:2A
3134::
3125::
2915::
2795::
2784:,
2780:,
2696:)/
2658::
2626::
2595:A2
2590:A1
2476::
2465:EC
2459::
2390:.
2382:.
2370:26
2368:.
2364:.
2314:.
2290:73
2288:.
2267:}}
2263:{{
2249:73
2247:.
2222:69
2220:.
2195:95
2193:.
2170:.
2158:.
2135:.
2125:16
2123:.
2100:.
2092:.
2080:.
2053:.
2045:.
2035:64
2033:.
2010:.
1998:.
1975:.
1963:11
1961:.
1957:.
1934:.
1924:44
1922:.
1876:.
1864:43
1862:.
1858:.
1835:.
1827:.
1819:.
1807:.
1783:.
1771:83
1769:.
1765:.
1742:.
1732:.
1722:73
1720:.
1716:.
1682:.
1668:.
1664:.
1641:.
1627:.
1623:.
1600:.
1586:.
1582:.
1559:.
1551:.
1543:.
1531:.
1507:.
1493:.
1489:.
1466:.
1456:.
1425:.
1415:.
1384:.
1376:.
1368:.
1356:.
1333:.
1325:.
1317:.
1305:.
1293:^
1279:.
1271:.
1263:.
1251:19
1249:.
1237:^
1223:.
1215:.
1203:.
1180:.
1170:69
1168:.
1145:.
1133:.
1121:^
1055:.
1010:.
998:,
992:,
986:,
980:,
974:,
968:,
962:,
956:,
944:–
903:-
869:–
843:–
818:–
793:–
768:.
704:–
701:).
655::
580:,
520:.
410:.
372:.
163:.
131:,
102:LY
98:LY
85:eɪ
79:aɪ
64:eɪ
58:aɪ
41:,
28::
4128::
3690:2
3578:e
3571:t
3564:v
3545:)
3541:(
3532:)
3528:(
3519:)
3515:(
3506:)
3502:(
3493:)
3489:(
3480:)
3476:(
3467:)
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