411:
467:
344:-like, preneuronal, and intermediate types, while not affecting early neuronal type cells; suggesting ethanol treatment alters the precursor cell pool. Furthermore, there is a greater decrease in differentiation and immature neurons than there is in proliferating progenitors, suggesting that the abnormal decrease in the percentage of actively dividing preneuronal progenitors results in a greater reduction in the maturation and survival of postmitotic cells.
3118:
33:
125:
580:
372:. As an example, long-term chronic alcoholics suffer a variety of cognitive deficiencies. However, multiyear abstinence resolves most neurocognitive deficits, except for some lingering deficits in spatial processing. Nevertheless there are some frequent long-term consequences that are not reversible during abstinence. Alcohol
340:, and may arrest cells in the G1 phase, thus inhibiting their proliferation. Ethanol has different effects on different types of actively dividing hippocampal progenitors during their initial phases of neuronal development. Chronic alcohol exposure decreases the number of proliferating cells that are
347:
Additionally, alcohol exposure increased several markers of cell death. In these studies neural degeneration seems to be mediated by non-apoptotic pathways. One of the proposed mechanisms for alcohol’s neurotoxicity is the production of nitric oxide (NO), yet other studies have found alcohol-induced
299:
remodeling changes which may mediate long-term alterations. Additionally, adolescent rats pre-exposed to ethanol have higher basal levels of dopamine in the nucleus accumbens, along with a prolonged dopamine response in this area in response to a challenge dose of ethanol. Together, these results
165:
The effects can manifest much later—mid-life
Alcohol Use Disorder has been found to correlate with increased risk of severe cognitive and memory deficits in later life. Alcohol related brain damage is not only due to the direct toxic effects of alcohol; alcohol withdrawal, nutritional deficiency,
182:
and neuronal connectivity in different brain regions. These changes may make adolescents especially susceptible to the harmful effects of alcohol. Compared to adults, adolescents exposed to alcohol are more likely to exhibit cognitive deficits (including learning and memory dysfunction). Some of
161:
While the extent of causation is difficult to prove, alcohol intake – even at levels often considered to be low – "is negatively associated with global brain volume measures, regional gray matter volumes, and white matter microstructure" and these associations become stronger as alcohol intake
406:
changes within particular regions of the brain. For example, in rats exposed to alcohol for up to 5 days, there was an increase in histone 3 lysine 9 acetylation in the pronociceptin promoter in the brain amygdala complex. This acetylation is an activating mark for pronociceptin. The
174:
Consuming large amounts of alcohol over a period of time can impair normal brain development in humans. Deficits in retrieval of verbal and nonverbal information and in visuospatial functioning were evident in youths with histories of heavy drinking during early and middle adolescence.
410:
1682:
D'Addario C, Caputi FF, Ekström TJ, Di
Benedetto M, Maccarrone M, Romualdi P, Candeletti S (February 2013). "Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex".
157:
Despite these physiological effects in principle, in some cases occasional moderate consumption may have ancillary benefits on the brain due to social and psychological benefits if compared to alcohol abstinence and soberness.
312:
and glutamatergic signaling, which may affect the remodeling and functions of the adolescent brain. These changes are significant as alcohol’s effect on NMDARs could contribute to learning and memory dysfunction
1070:
Guasch RM, Tomas M, Miñambres R, Valles S, Renau-Piqueras J, Guerri C (2003). "RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol".
992:
Pascual M, Blanco AM, Cauli O, Miñarro J, Guerri C (2007). "Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats".
2529:
566:
Topiwala A, Ebmeier KP, Maullin-Sapey T, Nichols TE (2021-05-12). "No safe level of alcohol consumption for brain health: observational cohort study of 25,378 UK Biobank participants".
142:
consumption in older adults is associated with better cognition and well-being than abstinence, excessive alcohol consumption is associated with widespread and significant brain
247:. The exact mechanism by which various concentrations of ethanol either activates or inhibits TLR4/IL-1RI signaling is not currently known, though it may involve alterations in
3154:
1782:
43:
2453:
2458:
1863:
1115:"Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat"
208:
receptors on these cells to activate intracellular signal transduction pathways. Specifically, ethanol induces the phosphorylation of IL-1R-associated kinase (IRAK),
2840:
2402:
1264:
Oscar-Berman M, Valmas MM, Sawyer KS, Ruiz SM, Luhar RB, Gravitz ZR (2014). "Profiles of impaired, spared, and recovered neuropsychologic processes in alcoholism".
380:. Among 461 individuals who sought help for alcohol problems, followup was provided for up to 16 years. By 16 years, 54% of those who tried to remain abstinent
1035:
Fernandez-Lizarbe S, Pascual M, Gascon MS, Blanco A, Guerri C (2008). "Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages".
1744:
792:
Tapert SF, Brown GG, Kindermann SS, Cheung EH, Frank LR, Brown SA (February 2001). "fMRI measurement of brain dysfunction in alcohol-dependent young women".
392:
3834:
3704:
3043:
2613:
953:"Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes"
913:
Guerri C, Pascual MA (2010). "Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence".
104:
2595:
1945:
76:
3147:
538:
2583:
2102:
83:
3977:
209:
3501:
2566:
217:
2079:
877:
Brown SA, Tapert SF, Granholm E, Delis DC (February 2000). "Neurocognitive functioning of adolescents: effects of protracted alcohol use".
90:
3140:
2800:
2725:
154:
volume. This may imply that alternatives and generally aiming for lowest possible consumption could usually be the advisable approach.
4036:
4008:
3855:
3304:
2698:
2524:
2465:
2136:
1798:
336:, via decreases in neural stem cell proliferation and newborn cell survival. Alcohol decreases the number of cells in S-phase of the
72:
3557:
3083:
3063:
2506:
1550:
1281:
150:
participants – suggest that even "light" or "moderate" consumption of alcohol by itself harms the brain, such as by reducing brain
3610:
2517:
2313:
1737:
3476:
3567:
3459:
2693:
2173:
2126:
3961:
3616:
3210:
2338:
2156:
1960:
205:
3788:
1858:
399:
3637:
3470:
3435:
2779:
2746:
2534:
2008:
1950:
1868:
1853:
1843:
316:
17:
1161:"Alcohol inhibition of neurogenesis: A mechanism of hippocampal neurodegeneration in an adolescent alcohol abuse model"
51:
4001:
3865:
3794:
3782:
3440:
3194:
3121:
2473:
1787:
1730:
97:
597:
3562:
3275:
3229:
3180:
3166:
2989:
2952:
2730:
1981:
1873:
62:
47:
3871:
3665:
2888:
2554:
2443:
1996:
1905:
1848:
434:"Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence"
228:
407:
nociceptin/nociceptin opioid receptor system is involved in the reinforcing or conditioning effects of alcohol.
3430:
3394:
3328:
3312:
3265:
3238:
3017:
879:
794:
622:
Daviet R, Aydogan G, Jagannathan K, Spilka N, Koellinger PD, Kranzler HR, Nave G, Wetherill RR (4 March 2022).
398:
Long-term, stable consequences of chronic hazardous alcohol use are thought to be due to stable alterations of
239:
expression. The upregulation of these inflammatory mediators by ethanol is also associated with an increase in
213:
2419:
708:"History of Alcohol Use Disorders and Risk of Severe Cognitive Impairment: A 19-Year Prospective Cohort Study"
178:
During adolescence critical stages of neurodevelopment occur, including remodeling and functional changes in
3850:
3482:
3336:
3068:
2810:
2683:
1955:
166:
electrolyte disturbances, and liver damage are also believed to contribute to alcohol-related brain damage.
1215:"Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates"
466:
3936:
3897:
3728:
3626:
3506:
3446:
3425:
3384:
3373:
3317:
3220:
3185:
2641:
2588:
2544:
2429:
2397:
2188:
2161:
3631:
3605:
3415:
3354:
2434:
2018:
2013:
1917:
1879:
1772:
232:
3887:
3660:
3400:
3242:
2994:
2981:
2925:
2740:
2358:
2151:
2003:
1900:
1584:
Jangra A, Sriram CS, Pandey S, Choubey P, Rajput P, Saroha B, Bezbaruah BK, Lahkar M (October 2016).
635:
567:
373:
305:
221:
3920:
3805:
3749:
3739:
3582:
3493:
3347:
3342:
3234:
3205:
3073:
2947:
2688:
2673:
2623:
2328:
2318:
2097:
2027:
1815:
179:
3734:
3676:
3465:
2905:
2848:
2830:
2823:
2764:
2663:
2656:
2618:
2578:
2384:
2285:
2200:
2178:
2032:
1991:
1753:
1708:
1507:
1309:
1095:
1017:
301:
1427:"Rates and predictors of relapse after natural and treated remission from alcohol use disorders"
572:
3777:
3365:
3163:
2935:
2805:
2668:
2646:
2549:
2424:
2368:
2146:
2085:
2075:
2047:
2023:
1700:
1664:
1615:
1566:
1546:
1499:
1491:
1456:
1407:
1366:
1297:
1277:
1246:
1190:
1136:
1087:
1052:
1009:
974:
930:
895:
859:
810:
774:
739:
669:
651:
624:"Associations between alcohol consumption and gray and white matter volumes in the UK Biobank"
519:
501:
480:
Dunbar RI, Launay J, Wlodarski R, Robertson C, Pearce E, Carney J, MacCarron P (1 June 2017).
455:
341:
284:
276:
268:
3967:
3451:
2918:
2868:
2512:
2448:
2414:
2407:
2290:
2257:
2247:
1692:
1654:
1646:
1605:
1597:
1556:
1538:
1483:
1446:
1438:
1397:
1386:"Impact of craving on alcohol relapse during, and 12 months following, outpatient treatment"
1356:
1348:
1287:
1269:
1236:
1226:
1180:
1172:
1126:
1079:
1044:
1001:
964:
922:
887:
849:
841:
802:
766:
729:
719:
659:
643:
509:
493:
445:
3132:
3772:
3594:
3225:
3199:
3088:
2769:
2754:
2735:
2240:
2235:
2109:
1321:
639:
138:
has become a growing area of research focus. While researchers have found that moderate
3842:
3532:
3288:
3103:
2913:
2893:
2855:
2720:
2141:
2131:
2121:
1929:
1895:
1761:
1659:
1634:
1610:
1585:
1561:
1542:
1526:
1474:
El-Sayed MS, Ali N, Ali ZE (1 March 2005). "Interaction
Between Alcohol and Exercise".
1451:
1426:
1361:
1336:
1292:
1273:
1241:
1214:
1185:
1160:
891:
854:
829:
806:
770:
734:
707:
664:
623:
514:
481:
329:
139:
757:
Neiman J (Oct 1998). "Alcohol as a risk factor for brain damage: neurologic aspects".
200:
which can produce a proinflammatory response in the brain. Ethanol interacts with the
4030:
3189:
3078:
2959:
2863:
2759:
2348:
2280:
2230:
2225:
2210:
2205:
2183:
2092:
2059:
1924:
1793:
1487:
1442:
1352:
1131:
1114:
1005:
272:
252:
1712:
1511:
1099:
1021:
3688:
3038:
3028:
2818:
2114:
333:
309:
256:
183:
these cognitive effects, such as learning impairments, may persist into adulthood.
926:
1048:
969:
952:
3928:
3879:
2969:
2964:
2835:
2715:
2605:
2498:
2270:
2215:
1820:
403:
295:
H3 and H4 in the prefrontal cortex, nucleus accumbens, and striatum, suggesting
280:
151:
845:
724:
647:
584:
384:
professional help had relapsed, and 39% of those who tried to remain abstinent
4015:
3572:
3526:
3098:
2930:
2878:
2873:
2708:
2678:
2651:
2561:
2343:
2323:
2252:
1835:
1825:
1696:
497:
377:
369:
365:
337:
248:
147:
1495:
688:
655:
505:
3909:
3033:
2940:
2774:
2573:
2539:
2392:
2363:
2333:
2265:
2220:
2193:
2070:
2041:
1976:
1810:
1805:
1402:
1385:
1231:
1213:
Taffe MA, Kotzebue RW, Crean RD, Crawford EF, Edwards S, Mandyam CD (2010).
450:
433:
296:
244:
240:
224:
197:
1704:
1668:
1619:
1570:
1503:
1460:
1411:
1370:
1301:
1250:
1194:
1140:
1091:
1056:
1013:
978:
934:
899:
863:
814:
743:
673:
523:
459:
376:(compulsive need to consume alcohol) is frequently present long-term among
778:
3982:
3823:
3818:
3717:
3699:
3546:
3405:
2703:
2633:
2297:
288:
3948:
3649:
2795:
2353:
1912:
1650:
1176:
579:
292:
61:
if you can. Unsourced or poorly sourced material may be challenged and
1601:
1586:"Epigenetic Modifications, Alcoholic Brain and Potential Drug Targets"
1083:
598:"Sorry, wine lovers. No amount of alcohol is good for you, study says"
267:
Intermittent ethanol treatment causes a decrease in expression of the
220:. Activation of the IRAK/MAPK pathway leads to the stimulation of the
3761:
1722:
143:
1337:"Cognitive performance in long-term abstinent alcoholic individuals"
271:
type 2 (D2R) and a decrease in phosphorylation of 2B subunit of the
1525:
Krishnan HR, Sakharkar AJ, Teppen TL, Berkel TD, Pandey SC (2014).
1268:. Handbook of Clinical Neurology. Vol. 125. pp. 183–210.
300:
suggest that alcohol exposure during adolescence can sensitize the
3093:
3001:
2166:
409:
236:
830:"The influence of substance use on adolescent brain development"
201:
3136:
1726:
539:"Study: No Amount Of Drinking Alcohol Is Safe For Brain Health"
706:
KuĹşma EB, Llewellyn DJ, Langa KM, Wallace RB, Lang IA (2014).
26:
1635:"Emerging Role of Epigenetic Mechanisms in Alcohol Addiction"
561:
559:
1335:
Fein G, Torres J, Price LJ, Di
Sclafani V (September 2006).
263:
Changes in dopaminergic and glutamatergic signaling pathways
146:. Other data – including investigated brain-scans of 36,678
689:"Midlife Alcohol Abuse Linked to Severe Memory Impairment"
2530:
Ban on caffeinated alcoholic drinks in the United States
231:. These transcription factors cause the upregulation of
58:
951:
Blanco Am VS, Vallés SL, Pascual M, Guerri C (2005).
482:"Functional Benefits of (Modest) Alcohol Consumption"
1783:
Alcohol-related traffic crashes in the United States
3993:
3947:
3908:
3817:
3760:
3716:
3687:
3648:
3593:
3545:
3519:
3492:
3414:
3383:
3364:
3327:
3303:
3296:
3287:
3253:
3173:
3056:
3010:
2980:
2904:
2788:
2632:
2604:
2497:
2488:
2454:
List of countries by alcohol consumption per capita
2377:
2306:
2058:
1969:
1938:
1888:
1834:
1771:
1760:
828:Squeglia LM, Jacobus J, Tapert SF (January 2009).
2459:Alcohol consumption by youth in the United States
1864:Collaborative Study on the Genetics of Alcoholism
432:Lang I, Wallace RB, Huppert FA, Melzer D (2007).
3700:Acute intoxication from hallucinogens (bad trip)
2841:Foundation for Advancing Alcohol Responsibility
1219:Proceedings of the National Academy of Sciences
1208:
1206:
1204:
1159:Morris SA, Eaves DW, Smith AR, Nixon K (2009).
1154:
1152:
1150:
946:
944:
291:. It also causes changes in the acetylation of
218:p38 mitogen-activated protein kinase (p38 MAPK)
1113:Pascual M, Boix J, Felipo V, Guerri C (2009).
243:activity and a corresponding increase in cell
57:Please review the contents of the article and
3148:
1738:
391:Alcohol consumption can substantially impair
8:
2403:International Women's Collaboration Brew Day
712:The American Journal of Geriatric Psychiatry
3705:Hallucinogen persisting perception disorder
3300:
3293:
3155:
3141:
3133:
3044:Medicinal Liquor Prescriptions Act of 1933
2614:List of countries with alcohol prohibition
2494:
1768:
1745:
1731:
1723:
364:Many negative physiologic consequences of
73:"Long-term impact of alcohol on the brain"
1946:Short-term effects of alcohol consumption
1658:
1609:
1560:
1450:
1401:
1360:
1291:
1240:
1230:
1184:
1130:
968:
853:
733:
723:
663:
571:
513:
449:
212:, stress-activated protein kinase (SAPK)/
1533:. International Review of Neurobiology.
1527:"The epigenetic landscape of alcoholism"
136:long-term impact of alcohol on the brain
3835:Kindling (sedative–hypnotic withdrawal)
2584:Legal drinking age in the United States
424:
3978:Chronic solvent-induced encephalopathy
1317:
1307:
486:Adaptive Human Behavior and Physiology
351:
324:Inhibition of hippocampal neurogenesis
308:dopamine pathways to cause changes in
233:inducible nitric oxide synthase (iNOS)
196:Ethanol can trigger the activation of
3502:Alcohol-induced respiratory reactions
2567:List of dry communities by U.S. state
414:Results of alcohol consumption levels
7:
2080:List of methanol poisoning incidents
348:NO production to lead to apoptosis (
2801:Alcohol consumption recommendations
2726:Temperance and Good Citizenship Day
1633:Berkel TD, Pandey SC (April 2017).
360:Transient versus stable alterations
332:) causes a decrease in hippocampal
4009:Anabolic-androgenic steroids abuse
3638:Synthetic cannabinoid use disorder
2525:Alcohol packaging warning messages
2137:Alcohol use among college students
1799:Drunk driving in the United States
1543:10.1016/B978-0-12-801311-3.00003-2
1425:Moos RH, Moos BS (February 2006).
1274:10.1016/B978-0-444-62619-6.00012-4
892:10.1111/j.1530-0277.2000.tb04586.x
807:10.1111/j.1530-0277.2001.tb02204.x
771:10.1111/j.1530-0277.1998.tb04389.x
687:Caroline Cassels (July 30, 2014).
14:
3558:Caffeine-induced anxiety disorder
3084:Non-alcoholic fatty liver disease
3064:Index of alcohol-related articles
2507:Administrative License Suspension
3611:Cannabinoid hyperemesis syndrome
3117:
3116:
2518:Alcoholic beverage control state
2314:Andrew Johnson alcoholism debate
1488:10.2165/00007256-200535030-00005
1443:10.1111/j.1360-0443.2006.01310.x
1353:10.1111/j.1530-0277.2006.00185.x
1132:10.1111/j.1471-4159.2008.05835.x
1072:Journal of Neuroscience Research
1006:10.1111/j.1460-9568.2006.05298.x
994:European Journal of Neuroscience
578:
465:
123:
31:
3568:Caffeine-induced sleep disorder
3460:Fetal alcohol spectrum disorder
2127:Alcohol in association football
3962:Sudden sniffing death syndrome
3617:Intravenous marijuana syndrome
3211:Post-acute-withdrawal syndrome
2339:List of deaths through alcohol
2157:Epidemiology of binge drinking
1961:Subjective response to alcohol
1384:Bottlender M, Soyka M (2004).
1266:Alcohol and the Nervous System
59:add the appropriate references
1:
3789:Opioid-induced endocrinopathy
2824:Sweat alcohol content monitor
1859:Alcoholism in rural Australia
927:10.1016/j.alcohol.2009.10.003
573:10.1101/2021.05.10.21256931v1
22:Effect of alcohol consumption
4002:Anabolic-androgenic steroids
3529:(alcohol use disorder (AUD))
3471:Positional alcohol nystagmus
3436:Alcohol-related brain damage
2747:Adult Children of Alcoholics
2535:Drunk driving law by country
1951:Long-term effects of alcohol
1869:Disease theory of alcoholism
1854:Alcoholism in family systems
1844:Alcohol and Native Americans
1049:10.1016/j.molimm.2007.10.025
970:10.4049/jimmunol.175.10.6893
393:neurobiologically-beneficial
317:Effects of alcohol on memory
170:Adolescent brain development
18:Alcohol-related brain damage
3866:Benzodiazepine use disorder
3795:Opioid-induced constipation
3783:Opioid-induced hyperalgesia
3477:Wernicke–Korsakoff syndrome
3441:Alcohol withdrawal syndrome
3230:Substance-related disorders
3195:Substance-induced psychosis
3167:substance-related disorders
2474:International whisk(e)y day
1788:Driving under the influence
44:reliable medical references
4053:
3563:Caffeine-induced psychosis
3494:Respiratory tract diseases
3479:(WKS, Korsakoff psychosis)
3276:Combined drug intoxication
2990:Christian views on alcohol
2596:List of alcohol laws of US
1874:High-functioning alcoholic
846:10.1177/155005940904000110
725:10.1016/j.jagp.2014.06.001
648:10.1038/s41467-022-28735-5
328:Excessive alcohol intake (
15:
4037:Health effects of alcohol
3872:Benzodiazepine dependence
3856:Benzodiazepine withdrawal
3666:Prenatal cocaine exposure
3329:Gastrointestinal diseases
3112:
2889:Alcoholic spirits measure
2874:Low-alcoholic malt drinks
2555:Ignition interlock device
2444:Drunken monkey hypothesis
2277:Routes of administration
1906:Alcohol congener analysis
1849:Alcoholism in adolescence
1697:10.1007/s12031-012-9829-y
1119:Journal of Neurochemistry
498:10.1007/s40750-016-0058-4
395:and -demanding exercise.
50:or relies too heavily on
3431:Alcoholic polyneuropathy
3395:Alcohol-related dementia
3313:Alcoholic cardiomyopathy
3266:Polysubstance dependence
3239:Psychological dependence
880:Alcohol. Clin. Exp. Res.
795:Alcohol. Clin. Exp. Res.
237:cyclooxygenase-2 (COX-2)
3851:Benzodiazepine overdose
3483:Wernicke encephalopathy
3337:Alcoholic liver disease
3305:Cardiovascular diseases
3069:Alcohol and spaceflight
2811:Alcohol server training
2684:Managed alcohol program
2262:Binge drinking devices
1956:Pharmacology of ethanol
1639:Alcohol. Clin. Exp. Res
1341:Alcohol. Clin. Exp. Res
1232:10.1073/pnas.0912810107
759:Alcohol. Clin. Exp. Res
287:, and for only D2R the
3937:Amphetamine dependence
3898:Barbiturate dependence
3729:Green Tobacco Sickness
3627:Amotivational syndrome
3507:Alcoholic lung disease
3447:Alcoholic hallucinosis
3426:Alcoholic hallucinosis
3374:Alcoholic ketoacidosis
3318:Alcohol flush reaction
3186:Substance intoxication
2674:Alcohol rehabilitation
2642:Alcohol detoxification
2545:Field sobriety testing
2430:Health effects of wine
2398:International Beer Day
2162:Holiday heart syndrome
765:(7 Suppl): 346S–351S.
415:
368:are reversible during
3632:Cannabis use disorder
3355:Auto-brewery syndrome
2926:Disulfiram-like drugs
2466:Ritual use of alcohol
2435:Wine and food pairing
2420:Apéritif and digestif
2071:Adulterated moonshine
1918:Blood alcohol content
1880:Seeing pink elephants
1403:10.1093/alcalc/agh073
957:Journal of Immunology
628:Nature Communications
451:10.1093/ageing/afm001
413:
222:transcription factors
3888:Barbiturate overdose
3661:Cocaine intoxication
3401:Alcohol intoxication
3243:Substance dependence
2995:Alcohol in the Bible
2982:Religion and alcohol
2948:General anaesthetics
2741:Alcoholics Anonymous
2699:List of mixed drinks
2152:Alcohol intoxication
2067:Adulterated alcohol
1037:Molecular Immunology
255:complexes and actin
187:Mechanisms of action
3921:Stimulant psychosis
3806:Opioid use disorder
3750:Nicotine dependence
3740:Nicotine withdrawal
3583:Caffeine dependence
3343:Alcoholic hepatitis
3235:Physical dependence
3206:Neonatal withdrawal
3074:Gateway drug effect
2860:Low-alcohol drinks
2689:Non-alcoholic drink
2624:Temperance movement
2606:Alcohol prohibition
2329:Gilbert Paul Jordan
2319:Dionysian Mysteries
2103:on college campuses
2098:Alcohol advertising
1816:Public intoxication
1531:Int. Rev. Neurobiol
1225:(24): 11104–11109.
640:2022NatCo..13.1175D
180:synaptic plasticity
3735:Nicotine poisoning
3677:Cocaine dependence
3606:Cannabis arteritis
3466:Korsakoff syndrome
3366:Endocrine diseases
2906:Addiction medicine
2849:Get Your Sexy Back
2789:Alcohol limitation
2765:Sober living house
2731:Twelve-step groups
2664:Brief intervention
2657:Open-container law
2619:Neo-prohibitionism
2579:Legal drinking age
2385:Alcoholic beverage
2286:Alcohol inhalation
2201:Drinking in public
2179:Blackout Wednesday
2037:Beverage-specific
1754:Alcohol and health
1651:10.1111/acer.13338
1177:10.1002/hipo.20665
416:
4024:
4023:
3778:Opioid withdrawal
3541:
3540:
3515:
3514:
3130:
3129:
3052:
3051:
3002:Islam and alcohol
2936:Calcium carbimide
2806:Alcohol education
2694:List of cocktails
2669:Designated driver
2647:Alcohol-free zone
2550:Hip flask defence
2484:
2483:
2425:Hangover remedies
2369:Whiskey Rebellion
2359:Six o'clock swill
2147:Austrian syndrome
2086:Surrogate alcohol
2076:Denatured alcohol
2048:Red wine headache
1602:10.1159/000449486
1084:10.1002/jnr.10594
963:(10): 6893–6899.
834:Clin EEG Neurosci
718:(10): 1047–1054.
352:Neuroinflammation
285:nucleus accumbens
277:prefrontal cortex
275:(NMDAR2B) in the
269:dopamine receptor
192:Neuroinflammation
132:
131:
108:
4044:
3968:Toluene toxicity
3452:Delirium tremens
3348:Zieve's syndrome
3301:
3294:
3157:
3150:
3143:
3134:
3120:
3119:
2919:Chlordiazepoxide
2869:Low-alcohol beer
2513:Alcohol monopoly
2495:
2415:Drinking culture
2408:Women in brewing
2291:Vodka eyeballing
2258:Passive drinking
1769:
1747:
1740:
1733:
1724:
1717:
1716:
1685:J. Mol. Neurosci
1679:
1673:
1672:
1662:
1630:
1624:
1623:
1613:
1581:
1575:
1574:
1564:
1522:
1516:
1515:
1471:
1465:
1464:
1454:
1422:
1416:
1415:
1405:
1381:
1375:
1374:
1364:
1332:
1326:
1325:
1319:
1315:
1313:
1305:
1295:
1261:
1255:
1254:
1244:
1234:
1210:
1199:
1198:
1188:
1156:
1145:
1144:
1134:
1110:
1104:
1103:
1067:
1061:
1060:
1043:(7): 2007–2016.
1032:
1026:
1025:
989:
983:
982:
972:
948:
939:
938:
910:
904:
903:
874:
868:
867:
857:
825:
819:
818:
789:
783:
782:
754:
748:
747:
737:
727:
703:
697:
696:
684:
678:
677:
667:
619:
613:
612:
610:
608:
594:
588:
583:Available under
582:
577:
575:
563:
554:
553:
551:
549:
534:
528:
527:
517:
477:
471:
470:
469:
463:
453:
429:
198:astroglial cells
127:
126:
118:
115:
109:
107:
66:
35:
34:
27:
4052:
4051:
4047:
4046:
4045:
4043:
4042:
4041:
4027:
4026:
4025:
4020:
3989:
3950:
3943:
3904:
3822:
3813:
3773:Opioid overdose
3756:
3712:
3683:
3644:
3589:
3537:
3511:
3488:
3417:
3410:
3387:system diseases
3386:
3379:
3360:
3323:
3283:
3255:
3249:
3226:Substance abuse
3169:
3161:
3131:
3126:
3108:
3089:Self-medication
3048:
3006:
2976:
2914:Benzodiazepines
2900:
2784:
2770:Sobering center
2755:Sober companion
2736:Al-Anon/Alateen
2628:
2600:
2490:
2480:
2373:
2302:
2242:In vino veritas
2236:Hair of the dog
2054:
1970:Adverse effects
1965:
1934:
1884:
1830:
1774:
1773:Alcohol-related
1764:
1756:
1751:
1721:
1720:
1681:
1680:
1676:
1632:
1631:
1627:
1583:
1582:
1578:
1553:
1524:
1523:
1519:
1476:Sports Medicine
1473:
1472:
1468:
1424:
1423:
1419:
1390:Alcohol Alcohol
1383:
1382:
1378:
1334:
1333:
1329:
1316:
1306:
1284:
1263:
1262:
1258:
1212:
1211:
1202:
1158:
1157:
1148:
1112:
1111:
1107:
1069:
1068:
1064:
1034:
1033:
1029:
991:
990:
986:
950:
949:
942:
912:
911:
907:
876:
875:
871:
827:
826:
822:
791:
790:
786:
756:
755:
751:
705:
704:
700:
686:
685:
681:
621:
620:
616:
606:
604:
602:Washington Post
596:
595:
591:
565:
564:
557:
547:
545:
536:
535:
531:
479:
478:
474:
464:
431:
430:
426:
421:
402:resulting from
400:gene expression
362:
326:
265:
251:clustering or
194:
189:
172:
128:
124:
119:
113:
110:
67:
56:
52:primary sources
36:
32:
23:
20:
12:
11:
5:
4050:
4048:
4040:
4039:
4029:
4028:
4022:
4021:
4019:
4018:
4013:
4012:
4011:
3997:
3995:
3991:
3990:
3988:
3987:
3986:
3985:
3983:Inhalant abuse
3980:
3972:
3971:
3970:
3965:
3955:
3953:
3945:
3944:
3942:
3941:
3940:
3939:
3925:
3924:
3923:
3914:
3912:
3906:
3905:
3903:
3902:
3901:
3900:
3892:
3891:
3890:
3876:
3875:
3874:
3869:
3860:
3859:
3858:
3853:
3843:benzodiazepine
3839:
3838:
3837:
3828:
3826:
3815:
3814:
3812:
3811:
3810:
3809:
3800:
3799:
3798:
3792:
3786:
3780:
3775:
3766:
3764:
3758:
3757:
3755:
3754:
3753:
3752:
3744:
3743:
3742:
3737:
3732:
3722:
3720:
3714:
3713:
3711:
3710:
3709:
3708:
3702:
3693:
3691:
3685:
3684:
3682:
3681:
3680:
3679:
3671:
3670:
3669:
3663:
3654:
3652:
3646:
3645:
3643:
3642:
3641:
3640:
3635:
3629:
3621:
3620:
3619:
3614:
3608:
3599:
3597:
3591:
3590:
3588:
3587:
3586:
3585:
3577:
3576:
3575:
3570:
3565:
3560:
3551:
3549:
3543:
3542:
3539:
3538:
3536:
3535:
3533:Binge drinking
3530:
3523:
3521:
3517:
3516:
3513:
3512:
3510:
3509:
3504:
3498:
3496:
3490:
3489:
3487:
3486:
3480:
3474:
3468:
3463:
3457:
3456:
3455:
3449:
3438:
3433:
3428:
3422:
3420:
3412:
3411:
3409:
3408:
3403:
3398:
3391:
3389:
3381:
3380:
3378:
3377:
3370:
3368:
3362:
3361:
3359:
3358:
3352:
3351:
3350:
3345:
3333:
3331:
3325:
3324:
3322:
3321:
3315:
3309:
3307:
3298:
3291:
3285:
3284:
3282:
3281:
3280:
3279:
3270:
3269:
3268:
3259:
3257:
3251:
3250:
3248:
3247:
3246:
3245:
3232:
3218:
3217:
3216:
3215:
3214:
3208:
3197:
3192:
3177:
3175:
3171:
3170:
3162:
3160:
3159:
3152:
3145:
3137:
3128:
3127:
3125:
3124:
3113:
3110:
3109:
3107:
3106:
3104:French paradox
3101:
3096:
3091:
3086:
3081:
3076:
3071:
3066:
3060:
3058:
3054:
3053:
3050:
3049:
3047:
3046:
3041:
3036:
3031:
3026:
3014:
3012:
3008:
3007:
3005:
3004:
2999:
2998:
2997:
2986:
2984:
2978:
2977:
2975:
2974:
2973:
2972:
2967:
2960:Sulfonic acids
2957:
2956:
2955:
2945:
2944:
2943:
2938:
2933:
2923:
2922:
2921:
2910:
2908:
2902:
2901:
2899:
2898:
2897:
2896:
2894:Standard drink
2891:
2883:
2882:
2881:
2876:
2871:
2866:
2858:
2856:Liquor license
2853:
2852:
2851:
2843:
2838:
2833:
2828:
2827:
2826:
2821:
2813:
2808:
2803:
2798:
2792:
2790:
2786:
2785:
2783:
2782:
2777:
2772:
2767:
2762:
2757:
2752:
2751:
2750:
2744:
2738:
2728:
2723:
2721:Temperance bar
2718:
2713:
2712:
2711:
2706:
2701:
2696:
2686:
2681:
2676:
2671:
2666:
2661:
2660:
2659:
2654:
2644:
2638:
2636:
2630:
2629:
2627:
2626:
2621:
2616:
2610:
2608:
2602:
2601:
2599:
2598:
2593:
2592:
2591:
2586:
2576:
2571:
2570:
2569:
2559:
2558:
2557:
2552:
2547:
2542:
2532:
2527:
2522:
2521:
2520:
2510:
2503:
2501:
2492:
2486:
2485:
2482:
2481:
2479:
2478:
2477:
2476:
2468:
2463:
2462:
2461:
2451:
2446:
2441:
2440:
2439:
2438:
2437:
2427:
2422:
2412:
2411:
2410:
2405:
2400:
2395:
2387:
2381:
2379:
2375:
2374:
2372:
2371:
2366:
2361:
2356:
2351:
2346:
2341:
2336:
2331:
2326:
2321:
2316:
2310:
2308:
2304:
2303:
2301:
2300:
2295:
2294:
2293:
2288:
2283:
2275:
2274:
2273:
2268:
2260:
2255:
2250:
2245:
2238:
2233:
2228:
2223:
2218:
2213:
2208:
2203:
2198:
2197:
2196:
2191:
2181:
2176:
2171:
2170:
2169:
2164:
2159:
2154:
2149:
2142:Binge drinking
2139:
2134:
2132:Alcohol powder
2129:
2124:
2122:Alcohol myopia
2119:
2118:
2117:
2107:
2106:
2105:
2095:
2090:
2089:
2088:
2083:
2073:
2064:
2062:
2056:
2055:
2053:
2052:
2051:
2050:
2044:
2035:
2030:
2021:
2016:
2011:
2006:
2001:
2000:
1999:
1989:
1984:
1979:
1973:
1971:
1967:
1966:
1964:
1963:
1958:
1953:
1948:
1942:
1940:
1936:
1935:
1933:
1932:
1930:Wine chemistry
1927:
1922:
1921:
1920:
1910:
1909:
1908:
1898:
1896:Beer chemistry
1892:
1890:
1886:
1885:
1883:
1882:
1877:
1871:
1866:
1861:
1856:
1851:
1846:
1840:
1838:
1832:
1831:
1829:
1828:
1823:
1818:
1813:
1808:
1803:
1802:
1801:
1791:
1785:
1779:
1777:
1766:
1758:
1757:
1752:
1750:
1749:
1742:
1735:
1727:
1719:
1718:
1674:
1645:(4): 666–680.
1625:
1596:(4): 246–260.
1576:
1551:
1517:
1482:(3): 257–269.
1466:
1417:
1376:
1347:(9): 1538–44.
1327:
1318:|journal=
1282:
1256:
1200:
1171:(5): 596–607.
1146:
1125:(4): 920–931.
1105:
1078:(4): 487–502.
1062:
1027:
1000:(2): 541–550.
984:
940:
905:
869:
820:
784:
749:
698:
679:
614:
589:
555:
529:
492:(2): 118–133.
472:
438:Age and Ageing
423:
422:
420:
417:
388:had relapsed.
361:
358:
330:binge drinking
325:
322:
264:
261:
259:organization.
193:
190:
188:
185:
171:
168:
130:
129:
122:
120:
39:
37:
30:
21:
13:
10:
9:
6:
4:
3:
2:
4049:
4038:
4035:
4034:
4032:
4017:
4014:
4010:
4007:
4006:
4004:
4003:
3999:
3998:
3996:
3992:
3984:
3981:
3979:
3976:
3975:
3973:
3969:
3966:
3963:
3960:
3959:
3957:
3956:
3954:
3952:
3946:
3938:
3935:
3934:
3932:
3930:
3926:
3922:
3919:
3918:
3916:
3915:
3913:
3911:
3907:
3899:
3896:
3895:
3893:
3889:
3886:
3885:
3883:
3881:
3877:
3873:
3870:
3867:
3864:
3863:
3861:
3857:
3854:
3852:
3849:
3848:
3846:
3844:
3840:
3836:
3833:
3832:
3830:
3829:
3827:
3825:
3820:
3816:
3807:
3804:
3803:
3801:
3796:
3793:
3790:
3787:
3784:
3781:
3779:
3776:
3774:
3771:
3770:
3768:
3767:
3765:
3763:
3759:
3751:
3748:
3747:
3745:
3741:
3738:
3736:
3733:
3730:
3727:
3726:
3724:
3723:
3721:
3719:
3715:
3706:
3703:
3701:
3698:
3697:
3695:
3694:
3692:
3690:
3686:
3678:
3675:
3674:
3672:
3667:
3664:
3662:
3659:
3658:
3656:
3655:
3653:
3651:
3647:
3639:
3636:
3633:
3630:
3628:
3625:
3624:
3622:
3618:
3615:
3612:
3609:
3607:
3604:
3603:
3601:
3600:
3598:
3596:
3592:
3584:
3581:
3580:
3578:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3555:
3553:
3552:
3550:
3548:
3544:
3534:
3531:
3528:
3525:
3524:
3522:
3518:
3508:
3505:
3503:
3500:
3499:
3497:
3495:
3491:
3484:
3481:
3478:
3475:
3472:
3469:
3467:
3464:
3461:
3458:
3453:
3450:
3448:
3445:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3423:
3421:
3419:
3413:
3407:
3404:
3402:
3399:
3396:
3393:
3392:
3390:
3388:
3382:
3375:
3372:
3371:
3369:
3367:
3363:
3356:
3353:
3349:
3346:
3344:
3341:
3340:
3338:
3335:
3334:
3332:
3330:
3326:
3319:
3316:
3314:
3311:
3310:
3308:
3306:
3302:
3299:
3295:
3292:
3290:
3286:
3277:
3274:
3273:
3271:
3267:
3264:
3263:
3261:
3260:
3258:
3256:substance use
3252:
3244:
3240:
3236:
3233:
3231:
3227:
3224:
3223:
3222:
3219:
3212:
3209:
3207:
3204:
3203:
3201:
3198:
3196:
3193:
3191:
3190:Drug overdose
3187:
3184:
3183:
3182:
3179:
3178:
3176:
3172:
3168:
3165:
3158:
3153:
3151:
3146:
3144:
3139:
3138:
3135:
3123:
3115:
3114:
3111:
3105:
3102:
3100:
3097:
3095:
3092:
3090:
3087:
3085:
3082:
3080:
3079:Mood disorder
3077:
3075:
3072:
3070:
3067:
3065:
3062:
3061:
3059:
3055:
3045:
3042:
3040:
3037:
3035:
3032:
3030:
3027:
3025:
3024:
3020:
3016:
3015:
3013:
3009:
3003:
3000:
2996:
2993:
2992:
2991:
2988:
2987:
2985:
2983:
2979:
2971:
2968:
2966:
2963:
2962:
2961:
2958:
2954:
2953:Nitrous oxide
2951:
2950:
2949:
2946:
2942:
2939:
2937:
2934:
2932:
2929:
2928:
2927:
2924:
2920:
2917:
2916:
2915:
2912:
2911:
2909:
2907:
2903:
2895:
2892:
2890:
2887:
2886:
2884:
2880:
2877:
2875:
2872:
2870:
2867:
2865:
2864:Fermented tea
2862:
2861:
2859:
2857:
2854:
2850:
2847:
2846:
2844:
2842:
2839:
2837:
2834:
2832:
2829:
2825:
2822:
2820:
2817:
2816:
2814:
2812:
2809:
2807:
2804:
2802:
2799:
2797:
2794:
2793:
2791:
2787:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2761:
2760:Sober curious
2758:
2756:
2753:
2748:
2745:
2742:
2739:
2737:
2734:
2733:
2732:
2729:
2727:
2724:
2722:
2719:
2717:
2714:
2710:
2707:
2705:
2702:
2700:
2697:
2695:
2692:
2691:
2690:
2687:
2685:
2682:
2680:
2677:
2675:
2672:
2670:
2667:
2665:
2662:
2658:
2655:
2653:
2650:
2649:
2648:
2645:
2643:
2640:
2639:
2637:
2635:
2631:
2625:
2622:
2620:
2617:
2615:
2612:
2611:
2609:
2607:
2603:
2597:
2594:
2590:
2587:
2585:
2582:
2581:
2580:
2577:
2575:
2572:
2568:
2565:
2564:
2563:
2560:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2537:
2536:
2533:
2531:
2528:
2526:
2523:
2519:
2516:
2515:
2514:
2511:
2508:
2505:
2504:
2502:
2500:
2496:
2493:
2487:
2475:
2472:
2471:
2469:
2467:
2464:
2460:
2457:
2456:
2455:
2452:
2450:
2449:Ladies' night
2447:
2445:
2442:
2436:
2433:
2432:
2431:
2428:
2426:
2423:
2421:
2418:
2417:
2416:
2413:
2409:
2406:
2404:
2401:
2399:
2396:
2394:
2391:
2390:
2388:
2386:
2383:
2382:
2380:
2376:
2370:
2367:
2365:
2362:
2360:
2357:
2355:
2352:
2350:
2349:Rum Rebellion
2347:
2345:
2342:
2340:
2337:
2335:
2332:
2330:
2327:
2325:
2322:
2320:
2317:
2315:
2312:
2311:
2309:
2305:
2299:
2296:
2292:
2289:
2287:
2284:
2282:
2281:Alcohol enema
2279:
2278:
2276:
2272:
2269:
2267:
2264:
2263:
2261:
2259:
2256:
2254:
2251:
2249:
2246:
2244:
2243:
2239:
2237:
2234:
2232:
2231:Flaming drink
2229:
2227:
2226:Dutch courage
2224:
2222:
2219:
2217:
2214:
2212:
2211:Drunk walking
2209:
2207:
2206:Drunk dialing
2204:
2202:
2199:
2195:
2192:
2190:
2187:
2186:
2185:
2184:Drinking game
2182:
2180:
2177:
2175:
2172:
2168:
2165:
2163:
2160:
2158:
2155:
2153:
2150:
2148:
2145:
2144:
2143:
2140:
2138:
2135:
2133:
2130:
2128:
2125:
2123:
2120:
2116:
2113:
2112:
2111:
2108:
2104:
2101:
2100:
2099:
2096:
2094:
2093:Alcohol abuse
2091:
2087:
2084:
2081:
2077:
2074:
2072:
2069:
2068:
2066:
2065:
2063:
2061:
2060:Social issues
2057:
2049:
2045:
2043:
2039:
2038:
2036:
2034:
2031:
2029:
2025:
2022:
2020:
2017:
2015:
2012:
2010:
2007:
2005:
2002:
1998:
1997:breast cancer
1995:
1994:
1993:
1990:
1988:
1985:
1983:
1980:
1978:
1975:
1974:
1972:
1968:
1962:
1959:
1957:
1954:
1952:
1949:
1947:
1944:
1943:
1941:
1937:
1931:
1928:
1926:
1925:Fusel alcohol
1923:
1919:
1916:
1915:
1914:
1911:
1907:
1904:
1903:
1902:
1899:
1897:
1894:
1893:
1891:
1887:
1881:
1878:
1875:
1872:
1870:
1867:
1865:
1862:
1860:
1857:
1855:
1852:
1850:
1847:
1845:
1842:
1841:
1839:
1837:
1833:
1827:
1824:
1822:
1819:
1817:
1814:
1812:
1809:
1807:
1804:
1800:
1797:
1796:
1795:
1794:Drunk driving
1792:
1789:
1786:
1784:
1781:
1780:
1778:
1776:
1770:
1767:
1763:
1759:
1755:
1748:
1743:
1741:
1736:
1734:
1729:
1728:
1725:
1714:
1710:
1706:
1702:
1698:
1694:
1690:
1686:
1678:
1675:
1670:
1666:
1661:
1656:
1652:
1648:
1644:
1640:
1636:
1629:
1626:
1621:
1617:
1612:
1607:
1603:
1599:
1595:
1591:
1587:
1580:
1577:
1572:
1568:
1563:
1558:
1554:
1552:9780128013113
1548:
1544:
1540:
1536:
1532:
1528:
1521:
1518:
1513:
1509:
1505:
1501:
1497:
1493:
1489:
1485:
1481:
1477:
1470:
1467:
1462:
1458:
1453:
1448:
1444:
1440:
1437:(2): 212–22.
1436:
1432:
1428:
1421:
1418:
1413:
1409:
1404:
1399:
1396:(4): 357–61.
1395:
1391:
1387:
1380:
1377:
1372:
1368:
1363:
1358:
1354:
1350:
1346:
1342:
1338:
1331:
1328:
1323:
1311:
1303:
1299:
1294:
1289:
1285:
1283:9780444626196
1279:
1275:
1271:
1267:
1260:
1257:
1252:
1248:
1243:
1238:
1233:
1228:
1224:
1220:
1216:
1209:
1207:
1205:
1201:
1196:
1192:
1187:
1182:
1178:
1174:
1170:
1166:
1162:
1155:
1153:
1151:
1147:
1142:
1138:
1133:
1128:
1124:
1120:
1116:
1109:
1106:
1101:
1097:
1093:
1089:
1085:
1081:
1077:
1073:
1066:
1063:
1058:
1054:
1050:
1046:
1042:
1038:
1031:
1028:
1023:
1019:
1015:
1011:
1007:
1003:
999:
995:
988:
985:
980:
976:
971:
966:
962:
958:
954:
947:
945:
941:
936:
932:
928:
924:
920:
916:
909:
906:
901:
897:
893:
889:
886:(2): 164–71.
885:
882:
881:
873:
870:
865:
861:
856:
851:
847:
843:
839:
835:
831:
824:
821:
816:
812:
808:
804:
801:(2): 236–45.
800:
797:
796:
788:
785:
780:
776:
772:
768:
764:
760:
753:
750:
745:
741:
736:
731:
726:
721:
717:
713:
709:
702:
699:
694:
690:
683:
680:
675:
671:
666:
661:
657:
653:
649:
645:
641:
637:
633:
629:
625:
618:
615:
603:
599:
593:
590:
586:
581:
574:
569:
562:
560:
556:
544:
540:
533:
530:
525:
521:
516:
511:
507:
503:
499:
495:
491:
487:
483:
476:
473:
468:
461:
457:
452:
447:
444:(3): 256–61.
443:
439:
435:
428:
425:
418:
412:
408:
405:
401:
396:
394:
389:
387:
383:
379:
375:
371:
367:
359:
357:
355:
353:
345:
343:
339:
335:
331:
323:
321:
319:
318:
311:
307:
303:
298:
294:
290:
286:
282:
278:
274:
273:NMDA receptor
270:
262:
260:
258:
254:
253:cell adhesion
250:
246:
242:
238:
234:
230:
226:
223:
219:
215:
211:
207:
203:
199:
191:
186:
184:
181:
176:
169:
167:
163:
159:
155:
153:
149:
145:
141:
137:
121:
117:
106:
103:
99:
96:
92:
89:
85:
82:
78:
75: –
74:
70:
69:Find sources:
64:
60:
54:
53:
49:
45:
40:This article
38:
29:
28:
25:
19:
4000:
3927:
3878:
3841:
3689:Hallucinogen
3416:Neurological
3164:Psychoactive
3039:Gin Act 1751
3029:Bratt System
3022:
3018:
2885:Measurement
2819:Breathalyzer
2589:Shoulder tap
2241:
2115:Beer goggles
1986:
1691:(2): 312–9.
1688:
1684:
1677:
1642:
1638:
1628:
1593:
1590:Ann Neurosci
1589:
1579:
1534:
1530:
1520:
1479:
1475:
1469:
1434:
1430:
1420:
1393:
1389:
1379:
1344:
1340:
1330:
1265:
1259:
1222:
1218:
1168:
1164:
1122:
1118:
1108:
1075:
1071:
1065:
1040:
1036:
1030:
997:
993:
987:
960:
956:
921:(1): 15–26.
918:
914:
908:
883:
878:
872:
837:
833:
823:
798:
793:
787:
762:
758:
752:
715:
711:
701:
695:. WebMD LLC.
692:
682:
631:
627:
617:
605:. Retrieved
601:
592:
546:. Retrieved
542:
532:
489:
485:
475:
441:
437:
427:
397:
390:
385:
381:
363:
349:
346:
334:neurogenesis
327:
314:
310:dopaminergic
306:mesocortical
266:
257:cytoskeleton
195:
177:
173:
164:
160:
156:
135:
133:
111:
101:
94:
87:
80:
68:
48:verification
41:
24:
3929:amphetamine
3880:barbiturate
3019:Beer Street
2970:Homotaurine
2965:Acamprosate
2836:Dry January
2815:Monitoring
2716:Teetotalism
2709:Malt drinks
2499:Alcohol law
2271:Yard of ale
2216:Drunkorexia
2028:intolerance
1821:Rum-running
1165:Hippocampus
840:(1): 31–8.
634:(1): 1175.
537:Ramirez E.
342:radial glia
281:hippocampus
162:increases.
152:grey matter
42:needs more
3910:Stimulants
3573:Caffeinism
3527:Alcoholism
3200:Withdrawal
3099:Town drunk
2931:Disulfiram
2879:Small beer
2845:Campaigns
2679:Drunk tank
2652:Dry campus
2562:Dry county
2344:Rum ration
2324:Dipsomania
2253:Pantsdrunk
2046:Red wine:
1836:Alcoholism
1826:Wine fraud
1537:: 75–116.
419:References
404:epigenetic
378:alcoholics
370:abstinence
366:alcoholism
338:cell cycle
302:mesolimbic
249:lipid raft
148:UK Biobank
114:April 2022
84:newspapers
16:See also:
4016:Chocolate
3418:disorders
3034:Dry state
2941:Cyanamide
2775:Sobrietol
2574:Last call
2540:DWI court
2393:Beer mile
2364:Speakeasy
2334:Gin Craze
2266:Beer bong
2221:Dry drunk
2194:Pregaming
2042:Potomania
2024:Tolerance
2014:Pregnancy
1889:Chemistry
1811:Nip joint
1806:Moonshine
1496:1179-2035
1431:Addiction
1320:ignored (
1310:cite book
656:2041-1723
585:CC BY 4.0
506:2198-7335
386:with help
297:chromatin
245:apoptosis
241:caspase 3
225:NF-kappaB
4031:Category
3949:Volatile
3824:hypnotic
3819:Sedative
3718:Nicotine
3595:Cannabis
3547:Caffeine
3406:Hangover
3254:Combined
3122:Category
3023:Gin Lane
2780:Quit lit
2704:Spritzer
2634:Sobriety
2489:Alcohol
2470:Whiskey
2298:Sconcing
2248:Nightcap
2174:Blackout
2004:Cortisol
1901:Congener
1713:14013417
1705:22684622
1669:28111764
1620:27780992
1571:25131543
1512:33487248
1504:15730339
1461:16445550
1412:15208171
1371:16930216
1302:25307576
1251:20534463
1195:19554644
1141:19077056
1100:22182633
1092:12704810
1057:18061674
1022:26318057
1014:17284196
979:16272348
935:20113871
900:10698367
864:19278130
815:11236838
744:25091517
693:Medscape
674:35246521
607:19 April
524:32104646
460:17353234
293:histones
289:striatum
3994:Related
3951:solvent
3762:Opioids
3650:Cocaine
3443:(AWS):
3385:Nervous
3339:(ALD):
3289:Alcohol
3174:General
3057:Related
3011:History
2796:0-0-1-3
2491:control
2378:General
2354:Shebeen
2307:History
1977:Anxiety
1939:Effects
1913:Ethanol
1762:Alcohol
1660:5378655
1611:5075742
1562:4337828
1452:1976118
1362:1868685
1293:4515358
1242:2890755
1186:2861155
915:Alcohol
855:2827693
779:9799959
735:4165640
665:8897479
636:Bibcode
568:medRxiv
548:13 June
515:7010365
382:without
374:craving
354:section
144:lesions
140:alcohol
98:scholar
63:removed
4005:: SUD
3964:(SSDS)
3707:(HPPD)
3462:(FASD)
3213:(PAWS)
2831:FRAMES
2040:Beer:
2033:Weight
2009:Memory
1992:Cancer
1775:crimes
1711:
1703:
1667:
1657:
1618:
1608:
1569:
1559:
1549:
1510:
1502:
1494:
1459:
1449:
1410:
1369:
1359:
1300:
1290:
1280:
1249:
1239:
1193:
1183:
1139:
1098:
1090:
1055:
1020:
1012:
977:
933:
898:
862:
852:
813:
777:
742:
732:
672:
662:
654:
570:
543:Forbes
522:
512:
504:
458:
216:, and
210:ERK1/2
206:IL-1RI
100:
93:
86:
79:
71:
3868:(BUD)
3808:(OUD)
3797:(OIC)
3791:(OIE)
3785:(OIH)
3731:(GTS)
3668:(PCE)
3634:(CUD)
3613:(CHS)
3473:(PAN)
3454:(DTs)
3397:(ARD)
3376:(AKA)
3357:(ABS)
3320:(AFR)
3278:(CDI)
3094:Spins
2749:(ACA)
2743:(AA):
2509:(ALS)
2389:Beer
2167:Zapoy
2019:Sleep
1987:Brain
1982:Aging
1876:(HFA)
1790:(DUI)
1709:S2CID
1508:S2CID
1096:S2CID
1018:S2CID
105:JSTOR
91:books
3974:SUD
3958:SID
3933:SUD
3917:SID
3894:SUD
3884:SID
3862:SUD
3847:SID
3831:SID
3802:SUD
3769:SID
3746:SUD
3725:SID
3696:SID
3673:SUD
3657:SID
3623:SUD
3602:SID
3579:SUD
3554:SID
3485:(WE)
3272:SID
3262:SUD
3021:and
2189:list
1701:PMID
1665:PMID
1616:PMID
1567:PMID
1547:ISBN
1500:PMID
1492:ISSN
1457:PMID
1408:PMID
1367:PMID
1322:help
1298:PMID
1278:ISBN
1247:PMID
1191:PMID
1137:PMID
1088:PMID
1053:PMID
1010:PMID
975:PMID
931:PMID
896:PMID
860:PMID
811:PMID
775:PMID
740:PMID
670:PMID
652:ISSN
609:2022
550:2021
520:PMID
502:ISSN
456:PMID
350:see
315:see
304:and
235:and
229:AP-1
227:and
204:and
202:TLR4
134:The
77:news
46:for
3520:SUD
3297:SID
3221:SUD
3181:SID
2110:Sex
1765:use
1693:doi
1655:PMC
1647:doi
1606:PMC
1598:doi
1557:PMC
1539:doi
1535:115
1484:doi
1447:PMC
1439:doi
1435:101
1398:doi
1357:PMC
1349:doi
1288:PMC
1270:doi
1237:PMC
1227:doi
1223:107
1181:PMC
1173:doi
1127:doi
1123:108
1080:doi
1045:doi
1002:doi
965:doi
961:175
923:doi
888:doi
850:PMC
842:doi
803:doi
767:doi
730:PMC
720:doi
660:PMC
644:doi
510:PMC
494:doi
446:doi
356:).
320:).
214:JNK
4033::
3241:/
3237:/
3228:/
3202::
3188:/
1707:.
1699:.
1689:49
1687:.
1663:.
1653:.
1643:41
1641:.
1637:.
1614:.
1604:.
1594:23
1592:.
1588:.
1565:.
1555:.
1545:.
1529:.
1506:.
1498:.
1490:.
1480:35
1478:.
1455:.
1445:.
1433:.
1429:.
1406:.
1394:39
1392:.
1388:.
1365:.
1355:.
1345:30
1343:.
1339:.
1314::
1312:}}
1308:{{
1296:.
1286:.
1276:.
1245:.
1235:.
1221:.
1217:.
1203:^
1189:.
1179:.
1169:20
1167:.
1163:.
1149:^
1135:.
1121:.
1117:.
1094:.
1086:.
1076:72
1074:.
1051:.
1041:45
1039:.
1016:.
1008:.
998:25
996:.
973:.
959:.
955:.
943:^
929:.
919:44
917:.
894:.
884:24
858:.
848:.
838:40
836:.
832:.
809:.
799:25
773:.
763:22
761:.
738:.
728:.
716:22
714:.
710:.
691:.
668:.
658:.
650:.
642:.
632:13
630:.
626:.
600:.
558:^
541:.
518:.
508:.
500:.
488:.
484:.
454:.
442:36
440:.
436:.
283:,
279:,
65:.
3931::
3882::
3845::
3821:/
3156:e
3149:t
3142:v
2082:)
2078:(
2026:/
1746:e
1739:t
1732:v
1715:.
1695::
1671:.
1649::
1622:.
1600::
1573:.
1541::
1514:.
1486::
1463:.
1441::
1414:.
1400::
1373:.
1351::
1324:)
1304:.
1272::
1253:.
1229::
1197:.
1175::
1143:.
1129::
1102:.
1082::
1059:.
1047::
1024:.
1004::
981:.
967::
937:.
925::
902:.
890::
866:.
844::
817:.
805::
781:.
769::
746:.
722::
676:.
646::
638::
611:.
587:.
576:.
552:.
526:.
496::
490:3
462:.
448::
313:(
116:)
112:(
102:·
95:·
88:·
81:·
55:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.