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PET radiotracer

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systems it is often used to quantify the binding of a test molecule to the binding site of radioligand. The higher the affinity of the molecule the more radioligand is displaced from the binding site and the increasing radioactive decay can be measured by
147:) of the PET-tracers must be high. In addition, since via the PET imaging technique is desired to investigate a function accurately, the selectivity of bindings to the specific targets is very important. 308: 143:
of molecules to receptors. Due to the probable injuries of PET-radiotracers, they could not be administered in the normal doses of the medications. Therefore, the binding affinity (P
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technique that produces a three-dimensional image of functional processes in the body. The system detects pairs of
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Bailey, D.L; D.W. Townsend; P.E. Valk; M.N. Maisey (2005).
201:"Basics and principles of radiopharmaceuticals for PET/CT" 1101: 819: 804: 772: 637: 590: 532: 495: 468: 419: 396: 330: 57: 45: 21: 302: 199:Wadsak Wolfgang, Mitterhauser Markus (2010). 8: 241:Positron Emission Tomography: Basic Sciences 139:. This assay is commonly used to calculate 816: 309: 295: 287: 61:used for diagnosis in combination with PET 27: 194: 192: 16:Radioligand used for diagnostic purposes 188: 1306:Therapeutic radiopharmaceuticals (V10) 18: 7: 265:Carlson, Neil (January 22, 2012). 14: 244:. Secaucus, NJ: Springer-Verlag. 1: 205:European Journal of Radiology 98:interface of PET-radiotracers 1331:Positron emission tomography 167:Positron emission tomography 80:positron emission tomography 217:10.1016/j.ejrad.2009.12.022 1372: 1196: 26: 1351:Medicinal radiochemistry 172:Medicinal radiochemistry 162:List of PET radiotracers 157:Medicinal radiocompounds 110:emitted indirectly by a 1032:Gallium (Ga) gozetotide 581:Iodinated human albumin 332:Central nervous system 267:Physiology of Behavior 99: 1356:Chemicals in medicine 966:Fludeoxyglucose (18F) 893:Pittsburgh compound B 534:Cardiovascular system 93: 74:that is used for the 1346:Radiopharmaceuticals 1012:Fluorothymidine F-18 1007:Fluoroestradiol F-18 926:Desmethoxyfallypride 433:Sodium iodohippurate 319:radiopharmaceuticals 996:Fluorodeoxysorbitol 740:Fluoroethyltyrosine 679:Satumomab pendetide 82:imaging technique. 76:diagnostic purposes 39:radiopharmaceutical 1077:Piflufolastat F-18 951:Flotufolastat F-18 946:Flortaucipir (18F) 764:Piflufolastat F-18 735:Fluorodeoxyglucose 674:Capromab pendetide 497:Respiratory system 387:Flutemetamol (18F) 104:functional imaging 100: 94:A fully automated 1313: 1312: 1192: 1191: 1086:Rubidium chloride 1052:N-Methylspiperone 941:Florbetapir (18F) 936:Florbetaben (18F) 888:N-Methylspiperone 719:Iobenguane (131I) 706:Iobenguane (123I) 571:Rubidium chloride 383:Florbetapir (18F) 363:Iofetamine (123I) 65: 64: 1363: 1341:Nuclear medicine 1326:PET radiotracers 817: 716: 703: 690: 662:Hynic-octreotide 470:Gastrointestinal 368:Iolopride (123I) 358:Ioflupane (123I) 311: 304: 297: 288: 281: 280: 262: 256: 255: 235: 229: 228: 196: 141:binding constant 31: 19: 1371: 1370: 1366: 1365: 1364: 1362: 1361: 1360: 1316: 1315: 1314: 1309: 1308: 1302: 1198:Isotopes used: 1188: 1097: 808: 800: 795:Iodocholesterol 768: 745:Sodium fluoride 714: 701: 688: 633: 586: 528: 491: 464: 415: 398:Skeletal system 392: 326: 315: 285: 284: 277: 264: 263: 259: 252: 237: 236: 232: 198: 197: 190: 185: 153: 146: 137:scintillography 128: 88: 68:PET radiotracer 41: 22:PET radiotracer 17: 12: 11: 5: 1369: 1367: 1359: 1358: 1353: 1348: 1343: 1338: 1333: 1328: 1318: 1317: 1311: 1310: 1303: 1301: 1300: 1295: 1290: 1288:technetium-99m 1285: 1280: 1275: 1270: 1265: 1260: 1255: 1250: 1245: 1240: 1235: 1230: 1225: 1220: 1215: 1210: 1205: 1199: 1197: 1194: 1193: 1190: 1189: 1187: 1186: 1181: 1176: 1171: 1166: 1161: 1156: 1151: 1146: 1141: 1136: 1131: 1126: 1120: 1118: 1099: 1098: 1096: 1095: 1089: 1079: 1074: 1064: 1059: 1054: 1049: 1044: 1039: 1034: 1029: 1024: 1019: 1014: 1009: 1004: 999: 993: 988: 978: 973: 963: 958: 953: 948: 943: 938: 933: 928: 923: 918: 917: 916: 906: 900: 895: 890: 885: 880: 875: 870: 865: 860: 855: 850: 844: 833: 831: 814: 802: 801: 799: 798: 784: 778: 776: 774:Adrenal cortex 770: 769: 767: 766: 761: 760: 759: 749: 748: 747: 742: 737: 732: 722: 709: 696: 683: 682: 681: 676: 666: 665: 664: 659: 654: 643: 641: 635: 634: 632: 631: 626: 621: 615: 610: 600: 598: 588: 587: 585: 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1022:Flutemetamol 961:Fluciclovine 824: 730:Fluciclovine 693:Minretumomab 592:Inflammation 266: 260: 240: 233: 208: 204: 131: 129: 126:Pharmacology 116:radionuclide 101: 67: 66: 51: 1283:selenium-75 1273:rubidium-82 1263:nitrogen-13 1258:krypton-81m 1223:fluorine-18 1208:chromium-51 863:Carfentanil 809:(including 652:Arcitumomab 618:Tilmanocept 608:Exametazime 551:Tetrofosmin 344:Exametazime 317:Diagnostic 177:Radioligand 72:radioligand 1320:Categories 1304:See also: 1253:iodine-131 1248:iodine-125 1243:iodine-123 1238:indium-111 1233:gallium-68 1228:gallium-67 1092:Setoperone 1017:Fluspidine 1002:Fluorodopa 985:Altanserin 976:Flumazenil 931:Fallypride 898:Raclopride 883:Methionine 878:Flumazenil 849:(Cimbi-36) 455:Mertiatide 183:References 114:-emitting 108:gamma rays 52:PET-ligand 1298:xenon-133 1268:oxygen-15 1218:copper-64 1213:cobalt-57 1203:carbon-11 1103:gamma ray 956:Flubatine 903:Verapamil 847:25B-NBOMe 841:ME@HAPTHI 657:Votumumab 613:Sulesomab 596:infection 561:Imciromab 546:Sestamibi 373:Iomazenil 102:PET is a 86:Mechanism 37:labelled 35:carbon-11 972:analogue 821:positron 757:Dotatate 225:20181453 151:See also 112:positron 47:Synonyms 970:glucose 914:Ammonia 858:Choline 853:Acetate 811:tracers 474:Hepatic 132:in vivo 58:Purpose 1107:photon 1057:Nifene 1042:Mefway 968:(FDG)- 715:  702:  689:  519:Tc-MAA 486:SeHCAT 273:  248:  223:  120:tracer 1111:SPECT 1071:Water 1027:FMISO 998:(FDS) 639:Tumor 421:Renal 1047:MPPF 873:DTBZ 868:DASB 828:list 444:ETS2 271:ISBN 246:ISBN 221:PMID 78:via 1062:FET 825:PET 323:V09 213:doi 130:In 1322:: 1184:Xe 1179:Tl 1174:Tc 1169:Se 1164:Sm 1159:Kr 1139:In 1134:Ga 1129:Co 1124:Cr 1082:Rb 1037:Ga 921:Cu 789:/ 752:Cu 669:In 647:Tc 629:Ga 624:In 604:Tc 567:Rb 557:In 542:Tc 521:, 515:Tc 510:Kr 505:Xe 482:Se 457:, 451:Tc 439:Cu 406:Tc 385:, 346:, 340:Tc 219:. 209:73 207:. 203:. 191:^ 145:KD 33:A 1154:I 1149:I 1144:I 1117:) 1113:/ 1109:( 1105:/ 1094:) 1088:) 1084:( 1073:) 1069:( 1067:O 987:) 983:( 981:F 909:N 905:) 843:) 839:( 837:C 830:) 823:( 813:) 797:) 793:( 791:I 787:I 782:I 725:F 721:) 717:( 712:I 708:) 704:( 699:I 695:) 691:( 686:I 620:) 606:( 594:/ 583:) 579:( 577:I 573:) 569:( 563:) 559:( 553:) 544:( 525:) 517:( 488:) 484:( 472:/ 461:) 453:( 435:) 431:( 429:I 412:) 408:( 389:) 381:( 379:F 375:) 356:( 354:I 350:) 342:( 325:) 321:( 310:e 303:t 296:v 279:. 254:. 227:. 215:: 118:(

Index


carbon-11
radiopharmaceutical
Synonyms
radioligand
diagnostic purposes
positron emission tomography

radiosynthesis
functional imaging
gamma rays
positron
radionuclide
tracer
scintillography
binding constant
Medicinal radiocompounds
List of PET radiotracers
Positron emission tomography
Medicinal radiochemistry
Radioligand


"Basics and principles of radiopharmaceuticals for PET/CT"
doi
10.1016/j.ejrad.2009.12.022
PMID
20181453
Positron Emission Tomography: Basic Sciences
ISBN

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