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PHQ-9

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128:. The items ask about the patient's experience in the last two weeks. Questions are about the level of interest/pleasure in doing things (anhedonia), feeling down or depressed, sleep-related problems (sleeping too much/difficulty falling or staying asleep), low energy or fatigue, eating problems (poor appetite or eating too much), self-worth (feeling like a failure), ability to concentrate, psychomotor problems (speaking/moving slowly or fidgety/restless), and thoughts of suicide. Responses range from “0” (Not at all) to “3” (nearly every day). A tenth question asks about the extent to which the previously mentioned symptoms make functioning in daily life difficult. The response to the tenth question is not factored into the final score; however, clinicians may use the response to help gauge the patient's level of impairment. A massive study of almost 60,000 participants (involving 29 samples from seven countries and speaking five languages) that employed exploratory 222:(questions 1 and 2 on the PHQ-9). Any degree of suicidal thoughts counts toward a provisional diagnosis. The symptoms must also cause significant distress and loss of function. The PHQ-9 is limited to making a provisional diagnosis. It cannot be used to make an actual diagnosis. Only a trained clinician can do that. For example, a trained clinician can determine if the symptoms can be better explained by substance use or another medical or psychiatric condition. Clinicians, however, may use the PHQ-9 to evaluate the efficacy of treatments for depression. A change of PHQ-9 score to less than 10 is considered a “partial response” to treatment and a change of PHQ-9 score to less than 5 is considered to be “remission.” 414:
Unlike the PHQ-9, the GAD-7 does not generate provisional diagnoses. A clinical interview must be given to arrive at a clinical diagnosis. The GAD-2 is a 2-question shortened version of the GAD-7; it uses the first two items on the GAD-7. A total score that is greater than 3 indicates that a clinician should administer the full GAD-7 and conduct a clinical interview to assess the presence and type of anxiety disorder.
404:. The questions on the PHQ-15 account for 90% of all symptoms that providers observe in primary care settings. Patients must rate the extent to which symptoms bothered them over the last month. Responses range from "not at all" (a score of 0) to "bothered a lot" (a score of 2). Higher scores on the PHQ-15 are strongly associated with functional impairment, disability, and healthcare utilization. 360:, and substance abuse. It also is used in studies involving patients with physical disabilities as well as older adults, students, and adolescents. The PHQ-9 has been extensively used in research investigating the relationship between burnout and depression. The instrument is available in over 30 languages and may be valid for use in different ethnic groups. 389:
resource restraints may leave researchers unable to intervene with study participants who indicate that they have experienced suicidal thoughts. The absence of the ninth question has little effect on scoring between the PHQ-8 and PHQ-9. A study found that scores between the two tests are highly correlated (
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consists of all of the PHQ-9 instruments except for the last question (suicidal thoughts). The 8-item version of the instrument is commonly used in research on general population samples, which mostly comprises individuals who are not depressed. Researchers generally use the PHQ-8 because timing and
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Smarr KL, Keefer AL (November 2011). "Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II), Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9
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is a seven-item anxiety screening instrument developed in 2006 with a similar format to that of the PHQ-9. Total scores range from 0 to 21 with scores of 5, 10, and 15 indicating mild, moderate, and severe anxiety. Unlike the PHQ-9, clinicians use the GAD-7 to assess the severity of anxiety only.
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patients. However, some research suggests that the scale is not purely unidimensional, with the scale reflecting two latent factors, somatic and cognitive/affective factors. By contrast, the results of the massive study by Bianchi et al. (2022) indicate that the PHQ-9's total score is essentially
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between PHQ-9 scores obtained from in-person and phone interviews with the same patients was 0.84. The PHQ-9 showed acceptable psychometric properties in a rural Indian population. In general, psychometric research supports the use of total scores, i.e., summing the item scores, in research and
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The total sum of the responses roughly indexes levels of depression. Scores range from 0 to 27. In general, a total of 10 or above is suggestive of the presence of depression. Listed below are PHQ-9 totals, the levels of depression that they relate to, and suggested treatment for each level of
78:'s larger suite of trademarked products, called the Primary Care Evaluation of Mental Disorders (PRIME-MD). The PHQ-9 takes less than three minutes to complete. It is scored by simply adding up the individual items' scores. Each of the nine items reflects a 376:
is a shortened version of the PHQ-9. It contains the first 2 questions of the PHQ-9 and takes less than a minute to administer. A score of 3 or greater on the PHQ-2 will generally lead to the subsequent administration of the PHQ-9. The
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Bianchi, R., Verkuilen, J., Toker, S., Schonfeld, I. S., Gerber, M., Brähler, E., & Kroenke, K. (2022). Is the PHQ-9 a unidimensional measure of depression? A 58,272-participant study. ‘’Psychological Assessment, 34’’(6), 595–603.
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Bianchi, R., Verkuilen, J., Schonfeld, I. S., Hakanen, J. J., Jansson-Fröjmark, M., Manzano-García, G., Laurent, E., & Meier, L. L. (2021). Is burnout a depressive condition? A 14-sample meta-analytic and bifactor analytic study.
218:, MDD is likely if five or more of the nine criterion symptoms are present for “most of the day, nearly every day" over the past 2 weeks; however, one of the symptoms must be either depressed mood or 278:
Preliminary work using gold standard readability measures suggests that a significant minority of patients might find interpretation of the PHQ-9 difficult without support.
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Meier, S. T., & Kim, S. (2022). Meta-regression analyses of relationships between burnout and depression with sampling and measurement methodological moderators.
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Kroenke K, Spitzer RL, Williams JB, Löwe B (2010). "The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review".
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A patient may take the PHQ-9 in written form or be presented the survey items in interview form. The PHQ-9 questions reflect the diagnostic criteria for
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Prescribe prescription drugs. If there are poor responses to treatment, immediately refer the patient to a mental health specialist for counseling.
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disorders. Robert L. Spitzer, Janet B.W. Williams, and Kurt Kroenke developed the PHQ in the mid-1990s and the PHQ-9 in 1999 with a grant from
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Spitzer, R. L., Kroenke, K., Williams, J. B., & Löwe, B. (2006). A brief measure for assessing generalized anxiety disorder: The GAD-7.
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bifactor analysis showed the PHQ-9 is essentially unidimensional; cognitive-affective and somatic specific factors were relatively weak.
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adopted the PHQ-9 as a standard measure for depression screening. The PHQ-9 is also the most commonly used depression measure in the
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endorsed the PHQ-9 for measuring depression severity and responsiveness to treatment in adults in a primary care setting.
1089:"Validation of the PHQ-9 as a screening instrument for depression in diabetes patients in specialized outpatient clinics" 567: 608: 262:, a mental health professional validated depression diagnoses from PHQ-9 scores from 580 participants, resulting in 88% 129: 71: 1087:
van Steenbergen-Weijenburg KM, de Vroege L, Ploeger RR, Brals JW, Vloedbeld MG, Veneman TF, et al. (August 2010).
267: 263: 722: 258:, Kroenke et al. found that the correlation between the PHQ-9 and the SF-20 mental health scale was 0.73. To assess 92:
The PHQ-9 is the nine-item depression scale found in the 59-item PHQ. The PHQ is a self-administered version of the
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Kroenke, Spitzer, and Williams conducted validity and reliability research on the PHQ-9 in 2001. With regard to
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symptom of depression. Primary care providers can use the PHQ-9 to screen for possible depression in patients.
1140:"Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western Kenya" 214:
A provisional diagnosis of MDD can be made by using the pattern of responses to PHQ-9 items. According to the
378: 307: 657: 423: 46: 42: 698: 893: 511:"Utility of a New Procedure for Diagnosing Mental Disorders in Primary Care: The PRIME-MD 1000 Study" 894:"A readability analysis of the PHQ-9: How much of the general public may struggle to understand it?" 235: 62:) is a depressive symptom scale and diagnostic tool introduced in 2001 to screen adult patients in 1018: 966: 913: 546: 259: 255: 400:
is a 15-item scale derived from the larger PHQ. The PHQ-15 inquires in 15 symptoms relating to
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for the PHQ-9 was 0.89 in a sample comprising 3,000 primary care patients and 0.86 among 3,000
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Monahan PO, Shacham E, Reece M, Kroenke K, Ong'or WO, Omollo O, et al. (February 2009).
96:, a screening tool that assesses 12 mental and emotional health disorders. It has modules on 70:
and a possible depressive disorder. The PHQ-9 is a component of the larger self-administered
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De Man J, Absetz P, Sathish T, Desloge A, Haregu T, Oldenburg B, et al. (2021-05-13).
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Inoue T, Tanaka T, Nakagawa S, Nakato Y, Kameyama R, Boku S, et al. (July 2012).
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clinics. Researchers have used the PHQ-9 to study the mental health of patients with
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Make treatment plan, consider counseling, follow-up, and/or prescription drugs
1155: 859: 609:"Instruction Manual for Patient Health Questionnaire (PHQ) and GAD-7 Measures" 333: 1105: 804: 534: 1054: 843:"Are the PHQ-9 and GAD-7 Suitable for Use in India? A Psychometric Analysis" 349: 219: 1192: 1173: 1124: 1073: 1014: 962: 878: 822: 492: 302:, the National Epidemiologic Survey on Alcohol and Related Conditions, the 542: 357: 341: 364:
owns the copyright of the PHQ-9 and allows it to be accessed for free.
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Studies found the PHQ-9 is also useful for screening for depression in
74:(PHQ), but can be used as a stand-alone instrument. The PHQ is part of 27: 954: 1208: 764: 361: 109: 75: 66:
settings. The instrument assesses for the presence and severity of
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Kroenke, Kurt; Spitzer, Robert L.; Williams, Janet B. W. (2001).
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Diagnostic and statistical manual of mental disorders: DSM-5-TR
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PHQ-9; PHQ Quick Depression Assessment; Resident mood interview
781:"The PHQ-9: Validity of a brief depression severity measure" 459:"The PHQ-9: validity of a brief depression severity measure" 246:
The test-retest reliability was found to be excellent. The
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uses this method to screen for depression in patients.
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Kroenke K, Spitzer RL, Williams JB (September 2001).
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National Institute for Health and Clinical Excellence
36: 26: 21: 1221:"Patient Health Questionnaire (PHQ-9 & PHQ-2)" 310:use the full PHQ-9 or a shortened form of it. The 296:National Health and Nutrition Examination Survey 1243:http://dx.doi.org/10.1001/archinte.166.10.1092 292:The Behavioral Risk Factor Surveillance Survey 1205:Journal of Occupational Health Psychology, 27 703:Pfizer's Patient-Centered Outcomes Assessment 8: 197:Prescribe prescription drugs and counseling 568:"PDF of the Patient Health Questionnaire-9" 681:American Psychiatric Association. (2022). 1277:Depression screening and assessment tools 1163: 1114: 1104: 1063: 1053: 868: 858: 812: 758: 756: 754: 482: 1193:https://doi.org/10.1177/2167702620979597 650:"Patient Health Questionnaire Screeners" 143: 22:Patient Health Questionnaire 9 item 434: 16:Self-report mood disorder questionnaire 1272:Anxiety screening and assessment tools 56:nine-item Patient Health Questionnaire 18: 988: 986: 984: 982: 980: 935: 933: 931: 929: 927: 836: 834: 832: 774: 772: 677: 675: 7: 1144:Journal of General Internal Medicine 797:10.1046/j.1525-1497.2001.016009606.x 785:Journal of General Internal Medicine 739:from the original on 10 January 2022 693: 691: 660:from the original on 10 January 2022 644: 642: 640: 625:from the original on 10 January 2022 603: 601: 599: 584:from the original on 10 January 2022 562: 560: 504: 502: 475:10.1046/j.1525-1497.2001.016009606.x 463:Journal of General Internal Medicine 452: 450: 448: 446: 444: 442: 440: 438: 1239:Archives of Internal Medicine, 166 1225:American Psychological Association 1209:https://doi.org/10.1037/ocp0000273 1007:10.1016/j.genhosppsych.2010.03.006 765:https://doi.org/10.1037/pas0001124 730:Patient Health Questionnaire (PHQ) 685:(5th ed.). Washington, DC: Author. 14: 1189:Clinical Psychological Science, 9 527:10.1001/jama.1994.03520220043029 306:Health Support program, and the 300:Medical Expenditure Panel Survey 1: 943:Arthritis Care & Research 910:10.53841/bpscpf.2021.1.347.18 1093:BMC Health Services Research 130:structural equation modeling 72:Patient Health Questionnaire 995:General Hospital Psychiatry 1293: 175:Repeat PHQ-9 at follow-up 1156:10.1007/s11606-008-0846-z 898:Clinical Psychology Forum 860:10.3389/fpsyg.2021.676398 509:Spitzer RL (1994-12-14). 136:Interpretation of results 122:major depressive disorder 1106:10.1186/1472-6963-10-235 226:Validity and reliability 1055:10.1186/1471-244X-12-73 949:(Suppl 11): S454–S466. 847:Frontiers in Psychology 723:"PHQ Screener Overview" 379:Veterans Administration 327:National Health Service 312:Veterans Administration 308:Millennium Cohort Study 153:Suggested Intervention 104:, alcohol, eating, and 654:Pfizer's PHQ Screeners 616:Pfizer's PHQ Screeners 575:Pfizer's PHQ Screeners 424:Psychological testing 316:Department of Defense 402:somatoform disorders 254:In an assessment of 150:Depression severity 892:Cuffe, Ray (2021). 699:"PCOA PHQ Screener" 368:Related instruments 124:(MDD) found in the 68:depressive symptoms 260:criterion validity 256:construct validity 234:, they found that 194:Moderately Severe 955:10.1002/acr.20556 521:(22): 1749–1756. 320:Kaiser Permanente 212: 211: 52: 51: 1284: 1245: 1235: 1229: 1228: 1217: 1211: 1201: 1195: 1184: 1178: 1177: 1167: 1135: 1129: 1128: 1118: 1108: 1084: 1078: 1077: 1067: 1057: 1033: 1027: 1026: 990: 975: 974: 937: 922: 921: 889: 883: 882: 872: 862: 838: 827: 826: 816: 776: 767: 760: 749: 748: 746: 744: 738: 727: 719: 713: 712: 710: 709: 695: 686: 679: 670: 669: 667: 665: 646: 635: 634: 632: 630: 624: 613: 605: 594: 593: 591: 589: 583: 572: 564: 555: 554: 506: 497: 496: 486: 454: 324:United Kingdom's 243:unidimensional. 236:Cronbach's alpha 144: 19: 1292: 1291: 1287: 1286: 1285: 1283: 1282: 1281: 1262: 1261: 1253: 1248: 1236: 1232: 1219: 1218: 1214: 1202: 1198: 1185: 1181: 1137: 1136: 1132: 1086: 1085: 1081: 1035: 1034: 1030: 992: 991: 978: 939: 938: 925: 891: 890: 886: 840: 839: 830: 778: 777: 770: 761: 752: 742: 740: 736: 725: 721: 720: 716: 707: 705: 697: 696: 689: 680: 673: 663: 661: 648: 647: 638: 628: 626: 622: 611: 607: 606: 597: 587: 585: 581: 570: 566: 565: 558: 508: 507: 500: 456: 455: 436: 432: 420: 370: 284: 276: 228: 138: 118: 90: 17: 12: 11: 5: 1290: 1288: 1280: 1279: 1274: 1264: 1263: 1260: 1259: 1252: 1251:External links 1249: 1247: 1246: 1230: 1212: 1207:(2), 195–206. 1196: 1191:(4), 579-597. 1179: 1150:(2): 189–197. 1130: 1079: 1042:BMC Psychiatry 1028: 1001:(4): 345–359. 976: 923: 904:(347): 18–22. 884: 828: 791:(9): 606–613. 768: 750: 714: 687: 671: 636: 595: 556: 498: 469:(9): 606–613. 433: 431: 428: 427: 426: 419: 416: 369: 366: 283: 280: 275: 272: 227: 224: 210: 209: 206: 203: 199: 198: 195: 192: 188: 187: 184: 181: 177: 176: 173: 170: 166: 165: 162: 159: 155: 154: 151: 148: 137: 134: 117: 114: 89: 86: 50: 49: 40: 34: 33: 30: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1289: 1278: 1275: 1273: 1270: 1269: 1267: 1258: 1257:Official site 1255: 1254: 1250: 1244: 1241:, 1092–1097. 1240: 1234: 1231: 1226: 1222: 1216: 1213: 1210: 1206: 1200: 1197: 1194: 1190: 1183: 1180: 1175: 1171: 1166: 1161: 1157: 1153: 1149: 1145: 1141: 1134: 1131: 1126: 1122: 1117: 1112: 1107: 1102: 1098: 1094: 1090: 1083: 1080: 1075: 1071: 1066: 1061: 1056: 1051: 1047: 1043: 1039: 1032: 1029: 1024: 1020: 1016: 1012: 1008: 1004: 1000: 996: 989: 987: 985: 983: 981: 977: 972: 968: 964: 960: 956: 952: 948: 944: 936: 934: 932: 930: 928: 924: 919: 915: 911: 907: 903: 899: 895: 888: 885: 880: 876: 871: 866: 861: 856: 852: 848: 844: 837: 835: 833: 829: 824: 820: 815: 810: 806: 802: 798: 794: 790: 786: 782: 775: 773: 769: 766: 759: 757: 755: 751: 735: 731: 724: 718: 715: 704: 700: 694: 692: 688: 684: 678: 676: 672: 659: 655: 651: 645: 643: 641: 637: 621: 617: 610: 604: 602: 600: 596: 580: 576: 569: 563: 561: 557: 552: 548: 544: 540: 536: 532: 528: 524: 520: 516: 512: 505: 503: 499: 494: 490: 485: 480: 476: 472: 468: 464: 460: 453: 451: 449: 447: 445: 443: 441: 439: 435: 429: 425: 422: 421: 417: 415: 412: 411: 405: 403: 399: 394: 392: 387: 382: 380: 375: 367: 365: 363: 359: 355: 351: 347: 343: 339: 335: 330: 328: 325: 321: 317: 313: 309: 305: 301: 297: 294:(BRFSS), the 293: 289: 281: 279: 273: 271: 269: 265: 261: 257: 252: 249: 244: 241: 237: 233: 225: 223: 221: 217: 207: 204: 201: 200: 196: 193: 190: 189: 185: 182: 179: 178: 174: 171: 168: 167: 163: 161:None-minimal 160: 157: 156: 152: 149: 146: 145: 142: 135: 133: 131: 127: 123: 115: 113: 111: 107: 103: 99: 95: 87: 85: 83: 82: 77: 73: 69: 65: 61: 57: 48: 44: 41: 39: 35: 31: 29: 25: 20: 1238: 1233: 1224: 1215: 1204: 1199: 1188: 1182: 1147: 1143: 1133: 1096: 1092: 1082: 1045: 1041: 1031: 998: 994: 946: 942: 901: 897: 887: 850: 846: 788: 784: 741:. 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Retrieved 574: 518: 514: 466: 462: 408: 406: 397: 395: 390: 385: 383: 373: 371: 354:fibromyalgia 346:chronic pain 331: 285: 282:Applications 277: 253: 245: 229: 215: 213: 147:PHQ-9 Score 141:depression: 139: 125: 119: 116:Survey items 91: 79: 64:primary care 59: 55: 53: 334:psychiatric 274:Readability 268:specificity 264:sensitivity 248:correlation 232:reliability 1266:Categories 941:(PHQ-9)". 853:: 676398. 743:10 January 708:2022-01-10 664:10 January 629:10 January 588:10 January 430:References 393:= 0.998). 251:practice. 106:somatoform 918:255873027 805:0884-8734 535:0098-7484 350:arthritis 220:anhedonia 183:Moderate 100:(PHQ-9), 1174:19031037 1125:20704720 1074:22759625 1023:34713999 1015:20633738 963:22588766 879:34054677 823:11556941 734:Archived 658:Archived 620:Archived 579:Archived 551:13836141 493:11556941 418:See also 358:epilepsy 342:HIV-AIDS 338:diabetes 304:Medicare 266:and 88% 94:PRIME-MD 28:Synonyms 1165:2629000 1116:2927590 1099:: 235. 1065:3416649 971:9086062 870:8155718 814:1495268 543:7966923 484:1495268 205:Severe 102:anxiety 88:History 47:54635-8 43:44249-1 1172:  1162:  1123:  1113:  1072:  1062:  1048:: 73. 1021:  1013:  969:  961:  916:  877:  867:  821:  811:  803:  549:  541:  533:  491:  481:  398:PHQ-15 362:Pfizer 318:, and 298:, the 240:OB-GYN 202:20-27 191:15-19 180:10-14 110:Pfizer 76:Pfizer 1019:S2CID 967:S2CID 914:S2CID 737:(PDF) 726:(PDF) 623:(PDF) 612:(PDF) 582:(PDF) 571:(PDF) 547:S2CID 410:GAD-7 386:PHQ-8 374:PHQ-2 216:DSM-5 172:Mild 164:None 126:DSM-5 81:DSM-5 60:PHQ-9 38:LOINC 1170:PMID 1121:PMID 1070:PMID 1011:PMID 959:PMID 875:PMID 819:PMID 801:ISSN 745:2022 666:2022 631:2022 590:2022 539:PMID 531:ISSN 515:JAMA 489:PMID 407:The 396:The 384:The 372:The 286:The 169:5-9 158:0-4 98:mood 54:The 1160:PMC 1152:doi 1111:PMC 1101:doi 1060:PMC 1050:doi 1003:doi 951:doi 906:doi 865:PMC 855:doi 809:PMC 793:doi 523:doi 519:272 479:PMC 471:doi 1268:: 1223:. 1168:. 1158:. 1148:24 1146:. 1142:. 1119:. 1109:. 1097:10 1095:. 1091:. 1068:. 1058:. 1046:12 1044:. 1040:. 1017:. 1009:. 999:32 997:. 979:^ 965:. 957:. 947:63 945:. 926:^ 912:. 900:. 896:. 873:. 863:. 851:12 849:. 845:. 831:^ 817:. 807:. 799:. 789:16 787:. 783:. 771:^ 753:^ 732:. 728:. 701:. 690:^ 674:^ 656:. 652:. 639:^ 618:. 614:. 598:^ 577:. 573:. 559:^ 545:. 537:. 529:. 517:. 513:. 501:^ 487:. 477:. 467:16 465:. 461:. 437:^ 356:, 352:, 348:, 344:, 340:, 314:, 270:. 112:. 45:, 1227:. 1176:. 1154:: 1127:. 1103:: 1076:. 1052:: 1025:. 1005:: 973:. 953:: 920:. 908:: 902:1 881:. 857:: 825:. 795:: 747:. 711:. 668:. 633:. 592:. 553:. 525:: 495:. 473:: 391:r 58:(

Index

Synonyms
LOINC
44249-1
54635-8
primary care
depressive symptoms
Patient Health Questionnaire
Pfizer
DSM-5
PRIME-MD
mood
anxiety
somatoform
Pfizer
major depressive disorder
structural equation modeling
anhedonia
reliability
Cronbach's alpha
OB-GYN
correlation
construct validity
criterion validity
sensitivity
specificity
National Institute for Health and Clinical Excellence
The Behavioral Risk Factor Surveillance Survey
National Health and Nutrition Examination Survey
Medical Expenditure Panel Survey
Medicare

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