218:, Howard McCordock, Robert Alan Moore, and Stanley Hartroft. The last of those individuals had concentrated his efforts almost exclusively at building a strong research program in the department, and Lacy furthered that process. Indeed, never having been trained in a clinical patient-care specialty, he took only passing interest in surgical pathology or laboratory medicine.
222:—one of the preeminent surgical pathologists of all time—was concurrently a faculty member in the Department of Surgery at Washington University. Ultimately, Lacy invited Ackerman to join his department; subsequently, the two had a reasonably cordial but somewhat-distant professional relationship for the next decade.
225:
Throughout the 1960s and early 1970s, Lacy collaborated with Walter F. Ballinger, chairperson of
Surgery at Washington University, on the experimental technique of beta islet-cell transplantation in animals as a treatment for diabetes mellitus. In 1989, that work eventuated in the first successful
245:
Lacy had a keen interest in literature, art, and music. He was married to his first wife, Ellen, for more than 50 years; the couple had two sons. Ellen died in 1998 of lung cancer. In 2002, Lacy married Bonnie
Mattingly. The following year, Lacy developed
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237:. Lacy remained on the Washington University faculty and retained an active role in diabetes research for another 20 years.
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islet-cell transplant in a human being. Research into the procedure continues, but it has still not been approved by the
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Scharp DW, Lacy PE, Santiago JV, et al.: Insulin independence after islet transplantation into type I diabetic patient.
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195:, using ultrastructural and fluorescent-antibody-labeling methods. That work resulted in a better understanding of how
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Lacy PE: Electron microscopy of the normal islets of
Langerhans: studies in the dog, rabbit, guinea pig, and rat.
377:
Ballinger WF II, Lacy PE, Scharp DW, Kemp DB, Knight M: Isografts and allografts of pancreatic islets in rats.
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Dehner LP, Kissane JM: Surgical pathology at the
Washington University Medical Center & Barnes Hospital.
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In 1961, Lacy was named the sixth chairman of
Pathology at Washington University, having been preceded by
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342:(Rosai J, Ed), American Registry of Pathology, Washington, D.C., 1997; pp. 111-144.
405:"Pancreatic Islet Transplantation - National Diabetes Information Clearinghouse"
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Lacy stepped down from his
Pathology chairmanship in 1984, and was succeeded by
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In 1955, Lacy was appointed assistant professor in the
Department of Anatomy at
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Ballinger WF II, Lacy PE: Transplantation of intact pancreatic islets in rats.
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191:. He undertook research into the characterization of endocrine cells in the
167:, for graduate work in anatomy and experimental pathology. He was awarded a
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degrees in 1944 and 1948, respectively. From there Lacy matriculated to the
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250:(idiopathic pulmonary fibrosis) that took his life on February 15, 2005.
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Obituary - The New York Times, February 18, 2005, Section A, p. 25.
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Obituary-The New York Times, February 18, 2005, Section A, p. 25
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Lacy PE, Davies J: Preliminary studies on the demonstration of
207:, and it steadily propelled Lacy through the academic ranks.
151:, both as an undergraduate and a medical student, obtaining
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researchers. He is often credited as the originator of
292:in the islets by the fluorescent antibody technic.
123:and experimentalist and one of the world’s leading
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53:
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23:
476:Ohio State University College of Medicine alumni
351:Ackerman LV: Training in surgical pathology .
119:(February 7, 1924 – February 15, 2005) was an
8:
481:Members of the National Academy of Medicine
143:in February, 1924. He was educated at the
456:Washington University in St. Louis faculty
20:
185:Washington University School of Medicine
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7:
230:as a mainstream clinical therapy.
105:Washington University in St. Louis
14:
228:U.S. Food and Drug Administration
471:University of Minnesota alumni
16:American anatomist (1924–2005)
1:
248:usual interstitial pneumonia
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340:Guiding the Surgeon's Hand
171:in that discipline by the
49:February 15, 2005 (age 81)
110:
79:
451:American diabetologists
173:University of Minnesota
163:and Mayo Foundation in
62:University of Minnesota
203:produced and exported
145:Ohio State University
129:islet transplantation
58:Ohio State University
201:islets of Langerhans
165:Rochester, Minnesota
446:American anatomists
311:pathology.wustl.edu
212:Eugene Lindsay Opie
189:St. Louis, Missouri
60:(B.S. & M.D.);
411:on 7 December 2013
394:1990; 39: 515-518.
368:1972; 72: 175-186.
355:1965; 80: 321-322.
199:in the pancreatic
296:1957; 6: 354-357.
279:1957; 6: 498-507.
139:Lacy was born in
125:diabetes mellitus
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81:Scientific career
74:diabetes mellitus
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407:. Archived from
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313:. Archived from
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34:February 7, 1924
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220:Lauren Ackerman
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117:Paul Eston Lacy
93:; Experimental
54:Alma mater
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40:, United States
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25:Paul Eston Lacy
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317:on 1 June 2010
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149:Columbus, Ohio
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241:Personal life
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141:Trinway, Ohio
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413:. Retrieved
409:the original
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319:. Retrieved
315:the original
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101:Institutions
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72:Research in
18:
466:2005 deaths
461:1924 births
353:Arch Pathol
235:Emil Unanue
161:Mayo Clinic
440:Categories
415:6 December
254:References
197:beta cells
379:Br J Surg
307:"History"
175:in 1955.
135:Education
121:anatomist
95:Pathology
392:Diabetes
294:Diabetes
277:Diabetes
216:Leo Loeb
193:pancreas
366:Surgery
290:insulin
205:insulin
91:Anatomy
64:(Ph.D.)
321:9 July
179:Career
87:Fields
169:Ph.D.
417:2013
323:2009
157:M.D.
155:and
153:B.S.
46:Died
31:Born
337:IN:
147:in
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