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are areas in the protein that are essential for its correct folding, usually in the transition of a protein from an inactive to an active state. Pro-sequences may also be involved in pro-protein transport and secretion.
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Protein precursors are often used by an organism when the subsequent protein is potentially harmful, but needs to be available on short notice and/or in large quantities.
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that targets them for secretion. Like other proteins that contain a signal peptide, their name is prefixed by
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or adding on another molecule. The name of the precursor for a protein is often prefixed by
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Some protein precursors are secreted from the cell. Many of these are synthesized with an
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Protein which after translation is cleaved into one or more smaller proteins
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Pro-domain (or prodomain) is the domain of a proprotein.
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153:. New York: Garland Science. p. 760.
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176:"Pro-sequence-assisted protein folding"
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254:. You can help Knowledge (XXG) by
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52:post-translational modification
174:Eder J, Fersht AR (May 1995).
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151:Molecular biology of the cell
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149:Alberts, Bruce (2002).
103:. They are thus called
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81:precursors are called
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227:at Wikimedia Commons
68:proopiomelanocortin
62:. Examples include
301:Precursor proteins
225:Precursor proteins
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72:prohormones
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64:proinsulin
83:zymogens
56:molecule
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