Knowledge (XXG)

Peter Gottfried Kremsner

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Mordmüller B, Supan C, Sim KL, Gómez-Pérez GP, Ospina Salazar CL, Held J, Bolte S, Esen M, Tschan S, Joanny F, Lamsfus Calle C, Löhr SJ, Lalremruata A, Gunasekera A, James ER, Billingsley PF, Richman A, Chakravarty S, Legarda A, Muñoz J, Antonijoan RM, Ballester MR, Hoffman SL, Alonso PL, Kremsner PG
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Mordmüller B, Surat G, Lagler H, Chakravarty S, Ishizuka AS, Lalremruata A, Gmeiner M, Campo JJ, Esen M, Ruben AJ, Held J, Calle CL, Mengue JB, Gebru T, Ibáñez J, Sulyok M, James ER, Billingsley PF, Natasha KC, Manoj A, Murshedkar T, Gunasekera A, Eappen AG, Li T, Stafford RE, Li M, Felgner PL, Seder
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Inc. Together with colleagues, he established a Plasmodium falciparum controlled human malaria infection (CHMI) model in Tübingen und Lambaréné. The Use of CHMI models dramatically reduces the time needed for clinical development of malaria vaccine and drug candidates. A study carried out in Tübingen
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Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, Liomba A, Kombila M, Bouyou-Akotet MK, Mawili Mboumba DP, Agbenyega T, Ansong D, Sylverken J, Ogutu BR, Otieno GA, Wangwe A, Bojang KA, Okomo U, Sanya-Isijola F, Newton CR, Njuguna P, Kazungu M, Kerb R, Geditz M, Schwab M,
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working there for the Superintendencia de Campanhas de Saude Publica at Rio Branco. From 1988 to 1996 he held the position of a group leader at the Institute of Tropical Medicine in Berlin. 1990 he earned his habilitation for Tropical Medicine and Specific Prophylaxis at the University of Vienna and
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Kremsner led numerous studies on tropical infectious diseases and is author of more than 700 scientific publications. Since the 1990s he is the most cited scientist in the field of parasitology in Germany and currently the most cited scientist in the fields of parasitology, tropical medicine and
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therapy and prophylaxis. Kremsner and his team developed a simplified method for assessment of severity of malaria. Outcome can now be predicted and therapy focused by health care providers using the "Lambaréné Score", which uses two clinical characteristics, coma and deep breathing without
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Kremsner is married to the lawyer Inge Thomforde. They have three children (Helene, Gottfried and Ferdinand). He is interested in classical music, arts and literature. In addition to his citizenship of the European Union (Austrian), Kremsner is also a Gabonese citizen.
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Lell B, MordmĂĽller B, Dejon Agobe JC, Honkpehedji J, Zinsou J, Mengue JB, Loembe MM, Adegnika AA, Held J, Lalremruata A, Nguyen TT, Esen M, Kc N, Ruben AJ, Chakravarty S, Lee Sim BK, Billingsley PF, James ER, Richie TL, Hoffman SL, Kremsner PG (February 2018).
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Helbok R, Kendjo E, Issifou S, Lackner P, Newton CR, Kombila M, Agbenyega T, Bojang K, Dietz K, Schmutzhard E, Kremsner PG (December 2009). "The Lambaréné Organ Dysfunction Score (LODS) is a simple clinical predictor of fatal malaria in African children".
125:/AS01, as a member of the governing clinical trial partnership committee and coordinator of clinical trials in Lambaréné. Since 2011, he and his team are working on development of other malaria vaccines, notably PfSPZ-based vaccines in cooperation with 966: 777:
Stanisic DI, McCarthy JS, Good MF. Controlled Human Malaria Infection: Applications, Advances, and Challenges. Infect Immun. 2017 Dec 19;86(1):e00479-17. doi: 10.1128/IAI.00479-17. PMID: 28923897; PMCID:
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laboratory assessment. This was accomplished by using data from a study in 26,000 children with severe malaria in Africa led by him. Kremsner took part in the phase 3 testing of the malaria vaccine,
788: 974: 731:"Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial" 360:"Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial" 1088: 87:
at the University of TĂĽbingen. Since 2008 he has been Chairman and Professor for Tropical Medicine, Travel Medicine and Parasitology at TĂĽbingen University as well as Director of the
43: 83:, now Centre de Recherches Médicales de Lambaréné (CERMEL), and made it one of the premier research and training centers in Africa. 1996 Kremsner was appointed Professor for 91:. In 2014 he was additionally appointed CEO of the Comprehensive Infectious Disease Center of University Hospital Tübingen. 2016 he became also adjunct professor at the 447:
Lell B, Luckner D, Ndjavé M, Scott T, Kremsner PG (March 1998). "Randomised placebo-controlled study of atovaquone plus proguanil for malaria prophylaxis in children".
900: 952: 882: 1048: 509: 70:. He started his academic career as a medical researcher at the Institute of Specific Prophylaxis and Tropical Medicine, University of Vienna. 1987 he went to 88: 533: 1083: 211:"Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon" 914: 645: 404:"Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres" 669: 1078: 621: 597: 23:
Peter Gottfried Kremsner, research physician and director of the Institute of Tropical Medicine in TĂĽbingen (Germany), in his office.
172: 19: 1010:"Gabon: Le professeur Peter Kremsner et le docteur Edgar Brice Ngoungou décrochent les 100.000.000 du Prix CENAREST 2010" 806: 92: 995: 39: 167: 142: 1053: 579: 315:"Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial" 113: 313:
Velavan TP, Nguetse C, Köhler C, Issifou S, Bolte S, Engleitner T, Mordmüller B, Krishna S (January 2016).
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Honorary Professor of the Institute of Clinical Medical and Pharmaceutical Sciences, Hanoi, Vietnam, 2018
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travel medicine in Europe (EU). He has been principal investigator on key studies for the development of
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Grand Prix of the Gabonese National Centre for Scientific and Technological Research (CENAREST), 2010
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applying a CHMI model showed 100 percent protection against the homologous malaria strain.
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International Honorary Fellow of American Society of Tropical Medicine and Hygiene, 2017
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1992 an additional habilitation for Tropical Medicine and Parasitology at the
807:"Kremsner: New malaria vaccine is '100 percent protective' - DW - 16.02.2017" 859: 764: 715: 439: 393: 350: 296: 255:"Sterile protection against human malaria by chemoattenuated PfSPZ vaccine" 244: 59: 468: 226: 547: 278: 789:"New process allows tailor-made malaria research - University Tübingen" 138: 126: 117: 35: 71: 707: 953:"Vietnamese – German centre of medical research launched in Hanoi" 826:"CureVac COVID vaccine let-down spotlights mRNA design challenges" 122: 47: 18: 38:) is a specialist in tropical medicine and Full Professor at the 253:
RA, Richie TL, Sim BK, Hoffman SL, Kremsner PG (February 2017).
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of Berlin. 1992 he started the medical research center in
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Fellow of the Royal College of Physicians, London, 2003
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The American Journal of Tropical Medicine and Hygiene
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Memento Research Prize for neglected diseases, 2017
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He studied medicine at the 163:EDCTP Dr. Pascoal Mocumbi Prize, 2023 7: 696:The Journal of Infectious Diseases 14: 1084:20th-century Austrian physicians 166: 548:"cermel.org/board of directors" 89:Institute for Tropical Medicine 141:'s Covid-19 vaccine candidate 116:and parenteral artesunate for 1: 747:10.1016/S0140-6736(15)60721-8 461:10.1016/S0140-6736(97)09222-2 376:10.1016/S0140-6736(15)60721-8 332:10.1371/journal.pmed.1001938 93:Medical University of Vienna 824:Dolgin, Elie (2021-06-18). 1105: 1079:German tropical physicians 887:www.schwarzwaelder-bote.de 851:10.1038/d41586-021-01661-0 1032:www.antibiotikamonitor.at 421:10.1186/s12936-015-0628-0 66:, graduating in 1985 as 28:Peter Gottfried Kremsner 173:National Order of Merit 114:artesunate/pyronaridine 110:artesunate/amodiaquine 40:University of TĂĽbingen 24: 227:10.4269/ajtmh.17-0343 201:Selected publications 30:(born 16 May 1961 in 22: 793:www.uni-tuebingen.de 106:atovaquone/proguanil 64:University of Vienna 58:Kremsner grew up in 50:, now as president. 842:2021Natur.594..483D 568:. 28 November 2013. 279:10.1038/nature21060 271:2017Natur.542..445M 77:Humboldt University 68:Doctor of Medicine 25: 16:Austrian physician 674:scholar.google.de 650:scholar.google.de 626:scholar.google.de 602:scholar.google.de 584:scholar.google.de 265:(7642): 445–449. 1096: 1049:Curriculum vitae 1036: 1035: 1024: 1018: 1017: 1016:. 1 August 2010. 1014:fr.allafrica.com 1006: 1000: 999: 992: 986: 985: 983: 982: 973:. 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Index


Wiener Neustadt
Austria
University of TĂĽbingen
Centre de Recherches Médicales de Lambaréné
Gabon
SigleĂź
University of Vienna
Doctor of Medicine
Brazil
Humboldt University
Lambaréné
Parasitology
Institute for Tropical Medicine
Medical University of Vienna
atovaquone/proguanil
artesunate/amodiaquine
artesunate/pyronaridine
malaria
RTS,S
Sanaria
PfSPZ vaccine
CureVac
CVnCoV

National Order of Merit
"Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon"
doi
10.4269/ajtmh.17-0343
PMC

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