87:. Lovell-Badge's team, collaborating with Peter Goodfellow and colleagues at the Imperial Cancer Research Fund in London, discovered a new candidate gene, Sry. Koopman and colleagues injected Sry into fertilized XX mouse eggs which as a result developed as males, thus proving the male sex-determining role of Sry. The discovery is regarded as one of the major achievements in molecular genetics in the 20th century.
99:
Establishing his own research group at the
University of Queensland, Brisbane, Australia in 1992, Koopman set out to discover new members of a growing family of genes related to Sry – "Sox" genes. Among the first discoveries was Sox9, a key regulator of skeletal and testis development, which carries
240:
Koopman instigated the
Australian Developmental Biology Workshop (2001- ), the Australian Sex Summit (2004- ), and the International Workshop on Sox Transcription Factors (2005 - ). He was organizer of the Cold Spring Harbor (USA) Workshop on Molecular Embryology of the Mouse (1995-1998), and Chair
82:
In 1988, Koopman was recruited to the
Medical Research Council's National Institute for Medical Research at Mill Hill, London, working first with Anne McLaren, then joining a team led by Robin Lovell-Badge to search for the Y chromosomal sex-determining gene. Koopman demonstrated that activity of
90:
Much of
Koopman's subsequent research has focused on understanding how Sry acts to direct the formation of testes in the embryo, triggering male development. This work has involved the identification and/or study of a large number of other genes involved in development of the testes or ovaries.
263:
Gubbay, John; Collignon, JĂ©rĂ´me; Koopman, Peter; Capel, Blanche; Economou, Androulla; MĂĽnsterberg, Andrea; Vivian, Nigel; Goodfellow, Peter; Lovell-Badge, Robin (July 1990). "A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically
183:
Koopman co-chairs the Equity and
Diversity Reference Group of the Australian Academy of Science and is a member of the Women in Health Science Working Committee of NHMRC Australia, and is involved in developing the Decadal Plan for Women in STEM commissioned by the Australian Government.
789:
Foster, Jamie W.; Dominguez-Steglich, Marina A.; Guioli, Silvana; Kwok, Cheni; Weller, Polly A.; Stevanović, Milena; Weissenbach, Jean; Mansour, Sahar; Young, Ian D. (December 1994). "Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene".
737:
Wright, Edwina; Hargrave, Murray R.; Christiansen, Jeffrey; Cooper, Leanne; Kun, Jutta; Evans, Timothy; Gangadharan, Uma; Greenfield, Andy; Koopman, Peter (January 1995). "The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos".
958:
François, Mathias; Caprini, Andrea; Hosking, Brett; Orsenigo, Fabrizio; Wilhelm, Dagmar; Browne, Catherine; Paavonen, Karri; Karnezis, Tara; Shayan, Ramin (19 October 2008). "Sox18 induces development of the lymphatic vasculature in mice".
906:
Pennisi, David; Gardner, Jennifer; Chambers, Doreen; Hosking, Brett; Peters, Josephine; Muscat, George; Abbott, Catherine; Koopman, Peter (April 2000). "Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice".
158:), Koopman began to engage with relevant clinicians and intersex advocacy and support groups. To cater for a need for unbiased information relating to the causes, types, impacts of DSD and options for affected people, Koopman authored a
1277:
Bowles, Josephine; Knight, Deon; Smith, Christopher; Wilhelm, Dagmar; Richman, Joy; Mamiya, Satoru; Yashiro, Kenta; Chawengsaksophak, Kallayanee; Wilson, Megan J. (28 April 2006). "Retinoid
Signaling Determines Germ Cell Fate in Mice".
174:
From 2012 to 2017, Koopman worked as the
University of Queensland's Executive Director of Research Integrity, providing academic stewardship of research integrity and managing allegations of research misconduct.
518:
Sinclair, Andrew H.; Berta, Philippe; Palmer, Mark S.; Hawkins, J. Ross; Griffiths, Beatrice L.; Smith, Matthijs J.; Foster, Jamie W.; Frischauf, Anna-Maria; Lovell-Badge, Robin (July 1990).
323:
Koopman, Peter; MĂĽnsterberg, Andrea; Capel, Blanche; Vivian, Nigel; Lovell-Badge, Robin (November 1990). "Expression of a candidate sex-determining gene during mouse testis differentiation".
166:’s Research Program in Human DSD. He continues to work with the Australian Pediatric Endocrine Group and a range of advocacy groups to improve dialogue and management of these conditions.
108:
1018:
Irrthum, Alexandre; Devriendt, Koenraad; Chitayat, David; Matthijs, Gert; Glade, Conrad; Steijlen, Peter M.; Fryns, Jean-Pierre; Van
Steensel, Maurice A. M.; Vikkula, Miikka (June 2003).
459:
Koopman, Peter; Gubbay, John; Collignon, JĂ©rĂ´me; Lovell-Badge, Robin (December 1989). "Zfy gene expression patterns are not compatible with a primary role in mouse sex determination".
1814:
1819:
1075:
Overman, Jeroen; Fontaine, Frank; Moustaqil, Mehdi; Mittal, Deepak; Sierecki, Emma; Sacilotto, Natalia; Zuegg, Johannes; Robertson, Avril AB; Holmes, Kelly (31 January 2017).
1337:
Spiller, Cassy M.; Feng, Chun-Wei; Jackson, Andrew; Gillis, Ad J. M.; Rolland, Antoine D.; Looijenga, Leendert H. J.; Koopman, Peter; Bowles, Josephine (15 November 2012).
1435:
Lee, Peter A.; Nordenström, Anna; Houk, Christopher P.; Ahmed, S. Faisal; Auchus, Richard; Baratz, Arlene; Baratz Dalke, Katharine; Liao, Lih-Mei; Lin-Su, Karen (2016).
723:
47:
from 1977 to 1979, majoring in genetics, and was a resident of Janet Clarke Hall. He undertook BSc
Honours research at the Birth Defects Research Institute (now the
385:
Koopman, Peter; Gubbay, John; Vivian, Nigel; Goodfellow, Peter; Lovell-Badge, Robin (May 1991). "Male development of chromosomally female mice transgenic for Sry".
244:
Koopman has trained 34 postdoctoral research staff and 28 PhD students. He has published more than 280 research papers that have been cited over 19,000 times.
27:(born 3 December 1959) is an Australian biologist best known for his role in the discovery and study of the mammalian Y-chromosomal sex-determining gene, Sry.
163:
111:
syndrome. Given the role of lymphatic vessels in tumour metastasis, Sox18 is being developed as a potential drug target for anti-metastatic cancer therapy.
1794:
1784:
1779:
62:. During this time, he also studied Japanese, Fine Arts and Dutch language and literature, receiving a BA degree from the University of Melbourne in 1985.
23:
114:
Koopman found that the human and mouse genomes contain 20 Sox genes, and he proposed the naming system for Sox genes that continues to be used today.
48:
1809:
1484:
230:
107:
Koopman's group also discovered Sox18, a switch gene that directs formation of the lymphatic vessels, and is defective in humans with
1253:
1020:"Mutations in the Transcription Factor Gene SOX18 Underlie Recessive and Dominant Forms of Hypotrichosis-Lymphedema-Telangiectasia"
84:
1552:
142:
in the fetal gonad, opening the way for new non-invasive diagnostics and targeted additional therapies for testicular cancers.
1527:
1509:
1789:
151:
1677:
606:
126:
during fetal development—cells that later become sperm or oocytes. His group discovered that the vitamin A metabolite
52:
1698:
1185:"Phylogeny of the SOX Family of Developmental Transcription Factors Based on Sequence and Structural Indicators"
134:, a critical step in the formation of gametes. They also demonstrated that the developmental signaling molecule
1528:"Women in Science, Technology, Engineering and Mathematics (STEM) Decadal Plan | Australian Academy of Science"
520:"A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif"
66:
1653:"How the Y Chromosome makes a male: Molecular genetic analysis of key sex-determining genes - UQ Researchers"
44:
150:
With a growing interest in human variations of sex development (alternatively known as DSD, differences or
1804:
1388:"Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors"
717:
849:
Hosking, Brett M.; Muscat, George E.O.; Koopman, Peter A.; Dowhan, Dennis H.; Dunn, Timothy L. (1995).
1578:"Molecular genetics of mammalian sexual development: Molecular roles of SRY and SOX9 - UQ Researchers"
1799:
1287:
968:
799:
531:
468:
394:
332:
273:
101:
43:. He attended Oberon High School in Geelong, where he was School Captain. He studied science at the
688:
Koopman P, Bullejos M, Bowles J. (2001). "Regulation of male sexual development by Sry and Sox9".
207:
2003: Amersham-Pharmacia
Biotech Medal, Australian Society for Biochemistry and Molecular Biology
1319:
1000:
940:
831:
771:
563:
500:
426:
364:
305:
1466:
1458:
1417:
1409:
1368:
1360:
1311:
1303:
1259:
1249:
1214:
1206:
1165:
1157:
1116:
1098:
1057:
1039:
992:
984:
932:
924:
888:
870:
823:
815:
763:
755:
705:
670:
652:
555:
547:
492:
484:
418:
410:
356:
348:
297:
289:
210:
2005: President's Medal, Australia and New Zealand Society for Cell and Developmental Biology
40:
36:
1448:
1399:
1350:
1339:"Endogenous Nodal signaling regulates germ cell potency during mammalian testis development"
1295:
1241:
1196:
1147:
1106:
1088:
1047:
1031:
976:
916:
878:
862:
807:
747:
697:
660:
644:
539:
476:
402:
340:
281:
1077:"Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice"
1291:
972:
803:
535:
472:
398:
336:
277:
1602:
1577:
1437:"Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care"
1111:
1076:
1052:
1019:
1652:
1152:
1135:
883:
850:
665:
632:
1773:
223:
127:
944:
775:
122:
Koopman's early work with Anne McLaren spawned an interest in the regulation of the
1750:"Peter Koopman (0000-0001-6939-0914) - ORCID | Connecting Research and Researchers"
1323:
1004:
835:
581:
567:
504:
430:
368:
309:
139:
83:
mouse homologues of the existing candidate, ZFY, was not consistent with a role in
1723:
851:"Trans-activation and DNA-binding properties of the transcription factor, Sox-18"
1485:"Committee—Equity and Diversity Reference Group | Australian Academy of Science"
1245:
192:
1981: First Class Honours, Department of Genetics, The University of Melbourne
445:
1462:
1413:
1364:
1307:
1210:
1161:
1102:
1043:
988:
928:
874:
866:
819:
759:
656:
551:
488:
414:
352:
293:
195:
1992: AMP Biomedical Research Award, Australian Society for Medical Research
58:
Continuing to work with Cotton, his PhD focused on stem cell differentiation
1299:
123:
1627:
1470:
1421:
1372:
1315:
1263:
1218:
1201:
1184:
1169:
1120:
1061:
996:
936:
709:
648:
633:"Seven new members of theSoxgene family expressed during mouse development"
1404:
1387:
1232:
Koopman P. (2016). "The Curious World of Gonadal Development in Mammals".
892:
827:
767:
674:
559:
496:
422:
360:
301:
155:
59:
1093:
980:
241:
of the Gordon Research Conference on Germinal Stem Cell Biology (2017).
51:) at the Royal Children's Hospital, Melbourne, under the supervision of
1749:
1355:
1338:
1134:
Schepers, Goslik E.; Teasdale, Rohan D.; Koopman, Peter (August 2002).
131:
1453:
1436:
751:
213:
2007: Australian Professorial Fellowship, Australian Research Council
204:
2002: Australian Professorial Fellowship, Australian Research Council
1183:
Bowles, Josephine; Schepers, Goslik; Koopman, Peter (November 2000).
811:
701:
543:
480:
406:
344:
285:
1603:"2002 Amersham Pharmacia Biotech Medallist: Professor Peter Koopman"
1035:
519:
920:
198:
1992: Australian Research Fellowship, Australian Research Council
135:
1699:"Professor Peter Anthony Koopman | Australian Academy of Science"
39:, to Dutch immigrant parents, and raised in the coastal town of
607:"Institute for Molecular Bioscience - University of Queensland"
631:
Wright, Edwina M.; Snopek, Bernadette; Koopman, Peter (1993).
1386:
Spiller, Cassy M.; Bowles, Josephine; Koopman, Peter (2013).
226:, Australian Society for Biochemistry and Molecular Biology
1553:"UQ researcher wins medal for excellence in gene research"
159:
1607:
Australian Society for Biochemistry and Molecular Biology
219:
2008: Fellow of the Australian Academy of Science (FAA)
201:
1998: Julian Wells Medal, Lorne Genome Conference Inc
78:
Discovery of Sry and the genetics of sex determination
35:
Peter Anthony Koopman was born on 3 December 1959 in
216:2007: Award for Research Excellence, GSK Australia
1392:The International Journal of Developmental Biology
65:He was awarded a Doctor of Science (DSc) from the
162:, published under the auspices of the Australian
229:2024: Suzanne Cory Medal, Australian Academy of
138:and its receptor Cripto regulate male germ cell
100:mutations in humans with the skeletal disorder
1815:Academic staff of the University of Queensland
380:
378:
258:
256:
8:
1820:Fellows of the Australian Academy of Science
1514:National Health and Medical Research Council
722:: CS1 maint: multiple names: authors list (
164:National Health and Medical Research Council
1510:"Women in health science working committee"
55:, and graduated with First Class Honours.
1452:
1403:
1354:
1200:
1151:
1110:
1092:
1051:
882:
664:
154:, variations in sex characteristics, or
1234:Current Topics in Developmental Biology
252:
109:hypotrichosis-lymphedema-telangiectasia
1024:The American Journal of Human Genetics
715:
49:Murdoch Children's Research Institute
7:
1795:Australian people of Dutch descent
1785:20th-century Australian biologists
1780:21st-century Australian biologists
1628:"President's Medal » ANZSCDB"
611:Institute for Molecular Bioscience
14:
1678:"Alumni Members | GSK Australia"
104:and associated XY sex reversal.
16:Australian biologist (born 1959)
1441:Hormone Research in Paediatrics
690:Journal of Experimental Zoology
130:stimulates germ cells to enter
1810:University of Melbourne alumni
444:The University of Queensland.
1:
1153:10.1016/s1534-5807(02)00223-x
152:disorders of sex development
1246:10.1016/bs.ctdb.2015.12.009
1836:
586:espace.library.uq.edu.au
67:University of Queensland
31:Early life and education
1724:"Peter Koopman - ASBMB"
1300:10.1126/science.1125691
45:University of Melbourne
1202:10.1006/dbio.2000.9883
867:10.1093/nar/23.14.2626
855:Nucleic Acids Research
637:Nucleic Acids Research
1657:researchers.uq.edu.au
1582:researchers.uq.edu.au
1405:10.1387/ijdb.130028pk
1189:Developmental Biology
1136:"Twenty Pairs of Sox"
53:Richard (Dick) Cotton
20:Peter Anthony Koopman
649:10.1093/nar/21.3.744
179:Equity and diversity
102:campomelic dysplasia
1790:People from Geelong
1292:2006Sci...312..596B
1094:10.7554/elife.21221
981:10.1038/nature07391
973:2008Natur.456..643F
804:1994Natur.372..525F
536:1990Natur.346..240S
473:1989Natur.342..940K
399:1991Natur.351..117K
337:1990Natur.348..450K
278:1990Natur.346..245G
73:Career and research
1703:www.science.org.au
1532:www.science.org.au
1489:www.science.org.au
1398:(2–3–4): 211–219.
1356:10.1242/dev.083006
1140:Developmental Cell
264:expressed genes".
236:Other achievements
188:Awards and honours
170:Research integrity
1454:10.1159/000442975
1349:(22): 4123–4132.
1286:(5773): 596–600.
967:(7222): 643–647.
861:(14): 2626–2628.
798:(6506): 525–530.
752:10.1038/ng0195-15
530:(6281): 240–244.
467:(6252): 940–942.
393:(6322): 117–121.
331:(6300): 450–452.
272:(6281): 245–250.
146:Intersex advocacy
85:sex determination
41:Torquay, Victoria
37:Geelong, Victoria
1827:
1765:
1764:
1762:
1760:
1745:
1739:
1738:
1736:
1734:
1720:
1714:
1713:
1711:
1709:
1695:
1689:
1688:
1686:
1684:
1674:
1668:
1667:
1665:
1663:
1649:
1643:
1642:
1640:
1638:
1624:
1618:
1617:
1615:
1613:
1599:
1593:
1592:
1590:
1588:
1574:
1568:
1567:
1565:
1563:
1549:
1543:
1542:
1540:
1538:
1524:
1518:
1517:
1506:
1500:
1499:
1497:
1495:
1481:
1475:
1474:
1456:
1432:
1426:
1425:
1407:
1383:
1377:
1376:
1358:
1334:
1328:
1327:
1274:
1268:
1267:
1229:
1223:
1222:
1204:
1180:
1174:
1173:
1155:
1131:
1125:
1124:
1114:
1096:
1072:
1066:
1065:
1055:
1030:(6): 1470–1478.
1015:
1009:
1008:
955:
949:
948:
903:
897:
896:
886:
846:
840:
839:
812:10.1038/372525a0
786:
780:
779:
734:
728:
727:
721:
713:
702:10.1002/jez.1089
685:
679:
678:
668:
628:
622:
621:
619:
617:
603:
597:
596:
594:
592:
578:
572:
571:
544:10.1038/346240a0
515:
509:
508:
481:10.1038/342940a0
456:
450:
449:
446:"UQ Researchers"
441:
435:
434:
407:10.1038/351117a0
382:
373:
372:
345:10.1038/348450a0
320:
314:
313:
286:10.1038/346245a0
260:
26:
1835:
1834:
1830:
1829:
1828:
1826:
1825:
1824:
1770:
1769:
1768:
1758:
1756:
1747:
1746:
1742:
1732:
1730:
1722:
1721:
1717:
1707:
1705:
1697:
1696:
1692:
1682:
1680:
1676:
1675:
1671:
1661:
1659:
1651:
1650:
1646:
1636:
1634:
1632:www.anzscdb.org
1626:
1625:
1621:
1611:
1609:
1601:
1600:
1596:
1586:
1584:
1576:
1575:
1571:
1561:
1559:
1551:
1550:
1546:
1536:
1534:
1526:
1525:
1521:
1508:
1507:
1503:
1493:
1491:
1483:
1482:
1478:
1434:
1433:
1429:
1385:
1384:
1380:
1336:
1335:
1331:
1276:
1275:
1271:
1256:
1231:
1230:
1226:
1182:
1181:
1177:
1133:
1132:
1128:
1074:
1073:
1069:
1017:
1016:
1012:
957:
956:
952:
909:Nature Genetics
905:
904:
900:
848:
847:
843:
788:
787:
783:
740:Nature Genetics
736:
735:
731:
714:
687:
686:
682:
630:
629:
625:
615:
613:
605:
604:
600:
590:
588:
580:
579:
575:
517:
516:
512:
458:
457:
453:
443:
442:
438:
384:
383:
376:
322:
321:
317:
262:
261:
254:
250:
238:
190:
181:
172:
148:
120:
97:
80:
75:
33:
22:
17:
12:
11:
5:
1833:
1831:
1823:
1822:
1817:
1812:
1807:
1802:
1797:
1792:
1787:
1782:
1772:
1771:
1767:
1766:
1740:
1715:
1690:
1669:
1644:
1619:
1594:
1569:
1544:
1519:
1501:
1476:
1447:(3): 158–180.
1427:
1378:
1329:
1269:
1254:
1224:
1195:(2): 239–255.
1175:
1146:(2): 167–170.
1126:
1067:
1036:10.1086/375614
1010:
950:
915:(4): 434–437.
898:
841:
781:
729:
696:(5): 463–474.
680:
623:
598:
573:
510:
451:
436:
374:
315:
251:
249:
246:
237:
234:
189:
186:
180:
177:
171:
168:
147:
144:
119:
116:
96:
93:
79:
76:
74:
71:
69:in July 2018.
32:
29:
15:
13:
10:
9:
6:
4:
3:
2:
1832:
1821:
1818:
1816:
1813:
1811:
1808:
1806:
1805:Living people
1803:
1801:
1798:
1796:
1793:
1791:
1788:
1786:
1783:
1781:
1778:
1777:
1775:
1755:
1751:
1744:
1741:
1729:
1725:
1719:
1716:
1704:
1700:
1694:
1691:
1679:
1673:
1670:
1658:
1654:
1648:
1645:
1633:
1629:
1623:
1620:
1608:
1604:
1598:
1595:
1583:
1579:
1573:
1570:
1558:
1554:
1548:
1545:
1533:
1529:
1523:
1520:
1515:
1511:
1505:
1502:
1490:
1486:
1480:
1477:
1472:
1468:
1464:
1460:
1455:
1450:
1446:
1442:
1438:
1431:
1428:
1423:
1419:
1415:
1411:
1406:
1401:
1397:
1393:
1389:
1382:
1379:
1374:
1370:
1366:
1362:
1357:
1352:
1348:
1344:
1340:
1333:
1330:
1325:
1321:
1317:
1313:
1309:
1305:
1301:
1297:
1293:
1289:
1285:
1281:
1273:
1270:
1265:
1261:
1257:
1255:9780128029565
1251:
1247:
1243:
1239:
1235:
1228:
1225:
1220:
1216:
1212:
1208:
1203:
1198:
1194:
1190:
1186:
1179:
1176:
1171:
1167:
1163:
1159:
1154:
1149:
1145:
1141:
1137:
1130:
1127:
1122:
1118:
1113:
1108:
1104:
1100:
1095:
1090:
1086:
1082:
1078:
1071:
1068:
1063:
1059:
1054:
1049:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1014:
1011:
1006:
1002:
998:
994:
990:
986:
982:
978:
974:
970:
966:
962:
954:
951:
946:
942:
938:
934:
930:
926:
922:
921:10.1038/74301
918:
914:
910:
902:
899:
894:
890:
885:
880:
876:
872:
868:
864:
860:
856:
852:
845:
842:
837:
833:
829:
825:
821:
817:
813:
809:
805:
801:
797:
793:
785:
782:
777:
773:
769:
765:
761:
757:
753:
749:
745:
741:
733:
730:
725:
719:
711:
707:
703:
699:
695:
691:
684:
681:
676:
672:
667:
662:
658:
654:
650:
646:
642:
638:
634:
627:
624:
612:
608:
602:
599:
587:
583:
577:
574:
569:
565:
561:
557:
553:
549:
545:
541:
537:
533:
529:
525:
521:
514:
511:
506:
502:
498:
494:
490:
486:
482:
478:
474:
470:
466:
462:
455:
452:
447:
440:
437:
432:
428:
424:
420:
416:
412:
408:
404:
400:
396:
392:
388:
381:
379:
375:
370:
366:
362:
358:
354:
350:
346:
342:
338:
334:
330:
326:
319:
316:
311:
307:
303:
299:
295:
291:
287:
283:
279:
275:
271:
267:
259:
257:
253:
247:
245:
242:
235:
233:
232:
227:
225:
224:Lemberg Medal
220:
217:
214:
211:
208:
205:
202:
199:
196:
193:
187:
185:
178:
176:
169:
167:
165:
161:
157:
153:
145:
143:
141:
137:
133:
129:
128:retinoic acid
125:
118:Germ cell sex
117:
115:
112:
110:
105:
103:
94:
92:
88:
86:
77:
72:
70:
68:
63:
61:
56:
54:
50:
46:
42:
38:
30:
28:
25:
21:
1757:. Retrieved
1753:
1743:
1731:. Retrieved
1727:
1718:
1706:. Retrieved
1702:
1693:
1681:. Retrieved
1672:
1660:. Retrieved
1656:
1647:
1635:. Retrieved
1631:
1622:
1610:. Retrieved
1606:
1597:
1585:. Retrieved
1581:
1572:
1560:. Retrieved
1556:
1547:
1535:. Retrieved
1531:
1522:
1513:
1504:
1492:. Retrieved
1488:
1479:
1444:
1440:
1430:
1395:
1391:
1381:
1346:
1342:
1332:
1283:
1279:
1272:
1237:
1233:
1227:
1192:
1188:
1178:
1143:
1139:
1129:
1084:
1080:
1070:
1027:
1023:
1013:
964:
960:
953:
912:
908:
901:
858:
854:
844:
795:
791:
784:
746:(1): 15–20.
743:
739:
732:
718:cite journal
693:
689:
683:
640:
636:
626:
614:. Retrieved
610:
601:
589:. Retrieved
585:
576:
527:
523:
513:
464:
460:
454:
439:
390:
386:
328:
324:
318:
269:
265:
243:
239:
228:
221:
218:
215:
212:
209:
206:
203:
200:
197:
194:
191:
182:
173:
149:
140:pluripotency
121:
113:
106:
98:
89:
81:
64:
57:
34:
19:
18:
1800:1959 births
1343:Development
1240:: 537–545.
582:"UQ eSpace"
1774:Categories
1759:10 October
1733:10 October
1708:10 October
1683:10 October
1662:10 October
1637:10 October
1612:10 October
1587:10 October
1562:10 October
1537:10 October
1494:10 October
643:(3): 744.
616:10 October
591:10 October
248:References
124:germ cells
1754:orcid.org
1463:1663-2818
1414:0214-6282
1365:0950-1991
1308:0036-8075
1211:0012-1606
1162:1534-5807
1103:2050-084X
1044:0002-9297
989:0028-0836
929:1061-4036
875:0305-1048
820:0028-0836
760:1061-4036
657:0305-1048
552:0028-0836
489:0028-0836
415:0028-0836
353:0028-0836
294:0028-0836
95:Sox genes
1471:26820577
1422:23784832
1373:23034635
1316:16574820
1264:26970639
1219:11071752
1170:12194848
1121:28137359
1062:12740761
997:18931657
945:24013687
937:10742113
776:22654180
710:11555853
156:intersex
60:in vitro
1748:ORCID.
1557:UQ News
1324:2514848
1288:Bibcode
1280:Science
1112:5283831
1053:1180307
1005:4416082
969:Bibcode
893:7651823
836:1472426
828:7990924
800:Bibcode
768:7704017
675:8441686
568:4364032
560:1695712
532:Bibcode
505:4303582
497:2480529
469:Bibcode
431:3331979
423:2030730
395:Bibcode
369:4322050
361:2247150
333:Bibcode
310:4270188
302:2374589
274:Bibcode
231:Science
160:website
132:meiosis
1469:
1461:
1420:
1412:
1371:
1363:
1322:
1314:
1306:
1262:
1252:
1217:
1209:
1168:
1160:
1119:
1109:
1101:
1060:
1050:
1042:
1003:
995:
987:
961:Nature
943:
935:
927:
891:
884:307084
881:
873:
834:
826:
818:
792:Nature
774:
766:
758:
708:
673:
666:309180
663:
655:
566:
558:
550:
524:Nature
503:
495:
487:
461:Nature
429:
421:
413:
387:Nature
367:
359:
351:
325:Nature
308:
300:
292:
266:Nature
222:2009:
1728:ASBMB
1320:S2CID
1081:eLife
1001:S2CID
941:S2CID
832:S2CID
772:S2CID
564:S2CID
501:S2CID
427:S2CID
365:S2CID
306:S2CID
136:Nodal
1761:2018
1735:2018
1710:2018
1685:2018
1664:2018
1639:2018
1614:2018
1589:2018
1564:2018
1539:2018
1496:2018
1467:PMID
1459:ISSN
1418:PMID
1410:ISSN
1369:PMID
1361:ISSN
1312:PMID
1304:ISSN
1260:PMID
1250:ISBN
1215:PMID
1207:ISSN
1166:PMID
1158:ISSN
1117:PMID
1099:ISSN
1058:PMID
1040:ISSN
993:PMID
985:ISSN
933:PMID
925:ISSN
889:PMID
871:ISSN
824:PMID
816:ISSN
764:PMID
756:ISSN
724:link
706:PMID
671:PMID
653:ISSN
618:2018
593:2018
556:PMID
548:ISSN
493:PMID
485:ISSN
419:PMID
411:ISSN
357:PMID
349:ISSN
298:PMID
290:ISSN
1449:doi
1400:doi
1351:doi
1347:139
1296:doi
1284:312
1242:doi
1238:116
1197:doi
1193:227
1148:doi
1107:PMC
1089:doi
1048:PMC
1032:doi
977:doi
965:456
917:doi
879:PMC
863:doi
808:doi
796:372
748:doi
698:doi
694:290
661:PMC
645:doi
540:doi
528:346
477:doi
465:342
403:doi
391:351
341:doi
329:348
282:doi
270:346
24:FAA
1776::
1752:.
1726:.
1701:.
1655:.
1630:.
1605:.
1580:.
1555:.
1530:.
1512:.
1487:.
1465:.
1457:.
1445:85
1443:.
1439:.
1416:.
1408:.
1396:57
1394:.
1390:.
1367:.
1359:.
1345:.
1341:.
1318:.
1310:.
1302:.
1294:.
1282:.
1258:.
1248:.
1236:.
1213:.
1205:.
1191:.
1187:.
1164:.
1156:.
1142:.
1138:.
1115:.
1105:.
1097:.
1087:.
1083:.
1079:.
1056:.
1046:.
1038:.
1028:72
1026:.
1022:.
999:.
991:.
983:.
975:.
963:.
939:.
931:.
923:.
913:24
911:.
887:.
877:.
869:.
859:23
857:.
853:.
830:.
822:.
814:.
806:.
794:.
770:.
762:.
754:.
742:.
720:}}
716:{{
704:.
692:.
669:.
659:.
651:.
641:21
639:.
635:.
609:.
584:.
562:.
554:.
546:.
538:.
526:.
522:.
499:.
491:.
483:.
475:.
463:.
425:.
417:.
409:.
401:.
389:.
377:^
363:.
355:.
347:.
339:.
327:.
304:.
296:.
288:.
280:.
268:.
255:^
1763:.
1737:.
1712:.
1687:.
1666:.
1641:.
1616:.
1591:.
1566:.
1541:.
1516:.
1498:.
1473:.
1451::
1424:.
1402::
1375:.
1353::
1326:.
1298::
1290::
1266:.
1244::
1221:.
1199::
1172:.
1150::
1144:3
1123:.
1091::
1085:6
1064:.
1034::
1007:.
979::
971::
947:.
919::
895:.
865::
838:.
810::
802::
778:.
750::
744:9
726:)
712:.
700::
677:.
647::
620:.
595:.
570:.
542::
534::
507:.
479::
471::
448:.
433:.
405::
397::
371:.
343::
335::
312:.
284::
276::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.