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cable greatly simplifies the implantation procedure compared to other retinal implants. Optical activation of the photovoltaic pixels allows scaling the implants to thousands of electrodes and retains natural coupling of the eye movements to visual perception. Studies in rats with retinal degeneration demonstrated that prosthetic vision with such subretinal implants preserves many features of natural vision, including flicker fusion at high frequencies (>20 Hz), adaptation to static images, antagonistic center-surround organization and non-linear summation of subunits in receptive fields, providing high spatial resolution.
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is designed to restore sight by electrically stimulating the surviving inner retinal neurons, primarily the bipolar cells. Photovoltaic retinal implants are completely wireless and powered by near-infrared illumination (880 nm) projected from the augmented-reality glasses. Lack of trans-scleral
66:, Pixium Vision) having 100μm pixels demonstrated that AMD patients perceive letters and other patterns with spatial resolution closely matching the pixel size. Moreover, central prosthetic vision is perceived simultaneously with the remaining natural peripheral vision.
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The next-generation implants with 20μm pixels provided grating acuity matching the natural limit of resolution in rats (28μm). Currently, such high-resolution implants are being optimized for human retina by
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Photovoltaic array implanted under the degenerate retina converts NIR light into electric current flowing through the tissue and stimulating the inner retinal neurons.
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Images captured by the camera are processed and projected onto the subretinal photovoltaic implant from the augmented-reality glasses using near-IR (880nm) light
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Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas
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in the 'image-processing' inner retinal layers are relatively well-preserved. This subretinal
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is a technology for restoration of sight to patients blinded by
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Clinical trial with the first-generation of such implants (
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