Knowledge (XXG)

Podophyllum peltatum

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40: 479: 31: 89: 464: 449: 509: 494: 66: 297:, while flowering stems produce a pair or more leaves with 1–8 flowers in the axil between the apical leaves. The flowers are white, yellow or red, 2–6 cm (1" to 2") diameter with 6–9 petals, and mature into a green, yellow or red fleshy fruit 2–5 cm (1 in to 2 in) long. 360:
to assist with nutrient uptake in infertile conditions. Mayapple plants are considered obligately dependent upon such mycorrhizae, although it may also be facultatively dependent upon rhizome age and soil nutrient levels. Plants are commonly found infected by the
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The unripe green fruit is toxic. The ripened yellow fruit is edible in small amounts, and is sometimes made into jelly, though when consumed in large amounts the fruit is poisonous. The rhizome, foliage, and roots are also poisonous. Mayapple contains
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Though the common name is mayapple, in some areas it is the flower that appears in early May, not the "apple". The fruit or "apple" is usually produced early in summer and ripens later in summer.
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All the parts of the plant are poisonous, including the green fruit, but once the fruit has turned yellow, it can be safely eaten. The ripe fruit does not produce toxicity.
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up to 20–40  cm (8 in to 16 in) diameter with 3–9 shallowly to deeply cut lobes. The plants produce several stems from a creeping underground
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derived from a single root. The stems grow to 30–40 cm (12 in to 16 in) tall, with palmately lobed umbrella-like
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Lewis, W.H. and M.P.F. Elvin-Lewis. 1977. Medical Botany. Plants Affecting Man's Health. Wiley, New York. 515 p. p. 123-124.
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p. 527–532. In: J. Janick and A. Whipkey (eds.), Trends in new crops and new uses. ASHS Press, Alexandria, VA.
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Watson, M.A. and five others. 2001. The developmental ecology of mycorrhizal associations in mayapple,
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agent. The rhizome of the mayapple has been used for a variety of medicinal purposes, originally by
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NatureServe Network Biodiversity Location Data accessed through NatureServe Explorer
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Wild Flowers: An Aid to Knowledge of our Wild Flowers and their Insect Visitors
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The Audubon Society Field Guide to North American Wildflowers, Eastern Region
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for their attractive foliage and flowers, and they are a larval host for the
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1896 illustration from Franz Eugen Köhler, Köhler's Medizinal-Pflanzen
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Moraes, R.M., H. Lata, E. Bedir, M. Maqbool, and K. Cushman. 2002.
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Goodman and Gilman's The Pharmacological Basis of Therapeutics
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On American Mayapple as a practical source of podophyllotoxin
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Species of flowering plants belonging to the barberry family
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Biota of North America Program 2013 county distribution map
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World Health Organisations's list of essential medicines
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Bunyard, Britt A. 2013 "Mayapple Rust Resurrection"
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Mayapples are woodland plants, typically growing in
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Plants used in traditional Native American medicine
1004: 801:. Iowa State University, Ada Hayden Herbarium (ISC) 788:, Berberidaceae. Evolutionary Ecology 15: 425–442. 866:. Project Gutenberg Literary Archive Foundation. 1428:Flora of the Great Lakes region (North America) 421:in removing warts, and two of its derivatives, 799:"Puccinia podophyllin Schwein. Mayapple rust" 8: 992: 64: 38: 29: 20: 895:Ernest Small and Paul M. Catling (1999), 923:61. Cytotoxic agents/Epipodophyllotoxins 890: 888: 437:and it is derived from podophyllotoxin. 661:Integrated Taxonomic Information System 610:United States Department of Agriculture 601:Germplasm Resources Information Network 528: 444: 429:, have shown promise in treating some 323:is a drug containing podophyllin and 7: 1423:Flora of the Appalachian Mountains 1418:Flora of the Eastern United States 557:. Arlington, Virginia: NatureServe 14: 1311:urn:lsid:ipni.org:names:107599-1 685:Flora of North America, Vol. 3, 507: 492: 477: 462: 447: 87: 952:"22nd Essential Medicines List" 976:. National Library of Medicine 835:; Olmstead, Nancy C. (1985) . 1: 606:Agricultural Research Service 335:is highly toxic if consumed. 748:United States Forest Service 545:NatureServe (5 April 2024). 356:Many species of plants have 303:The substance they contain ( 1438:Taxa named by Carl Linnaeus 954:. World Health Organization 1454: 1403:NatureServe secure species 386:Mayapple has been used by 327:that is used to treat the 860:Blanchan, Neltje (2002). 433:. Etoposide is among the 222: 215: 198: 191: 84:Scientific classification 82: 62: 53: 46: 37: 28: 23: 905:Canadian Medicinal Crops 720:pubchem.ncbi.nlm.nih.gov 1413:Flora of Eastern Canada 338:They are also grown as 226:Anapodophyllum peltatum 839:. Knopf. p. 418. 404:indigenous inhabitants 413:Mayapple can be used 1272:Podophyllum_peltatum 1036:Podophyllum peltatum 1006:Podophyllum peltatum 907:, NRC Research Press 899:Podophyllum peltatum 786:Podophyllum peltatum 774:USDA PLANTS Database 769:Podophyllum peltatum 739:Bess, James (2005). 701:"Mayapple, Mandrake" 594:Podophyllum peltatum 578:Podophyllum peltatum 549:Podophyllum peltatum 240:Podophyllum peltatum 202:Podophyllum peltatum 48:Podophyllum peltatum 833:Niering, William A. 632:Plants for a Future 406:and later by other 56:Conservation status 917:Brunton LL et al. 367:Allodus podophylli 1390: 1389: 1257:Open Tree of Life 998:Taxon identifiers 931:978-0-07-162442-8 716:"Podophyllotoxin" 703:. 31 August 2011. 344:golden borer moth 340:ornamental plants 264:American mandrake 236: 235: 230: 77: 1445: 1383: 1382: 1370: 1369: 1360: 1359: 1350: 1349: 1340: 1339: 1327: 1326: 1314: 1313: 1301: 1300: 1288: 1287: 1275: 1274: 1265: 1264: 1252: 1251: 1239: 1238: 1226: 1225: 1213: 1212: 1203: 1202: 1190: 1189: 1177: 1176: 1164: 1163: 1151: 1150: 1138: 1137: 1125: 1124: 1112: 1111: 1099: 1098: 1086: 1085: 1073: 1072: 1060: 1059: 1050: 1049: 1040: 1039: 1038: 1025: 1024: 1023: 993: 986: 985: 983: 981: 970: 964: 963: 961: 959: 948: 942: 939: 933: 925:Twelfth Edition 915: 909: 908: 892: 883: 874: 868: 867: 857: 851: 850: 829: 823: 816: 810: 809: 807: 806: 795: 789: 782: 776: 765: 759: 758: 756: 754: 745: 736: 730: 729: 727: 726: 711: 705: 704: 697: 691: 682: 676: 671: 665: 664: 649: 643: 642: 641: 639: 627: 621: 620: 618: 616: 588: 582: 576:The Plant List, 573: 567: 566: 564: 562: 542: 536: 533: 511: 496: 481: 466: 451: 388:American Indians 374:Toxicity and use 228: 204: 184:P. peltatum 92: 91: 71: 68: 67: 42: 33: 21: 1453: 1452: 1448: 1447: 1446: 1444: 1443: 1442: 1393: 1392: 1391: 1386: 1378: 1373: 1365: 1363: 1355: 1353: 1345: 1343: 1335: 1330: 1322: 1317: 1309: 1304: 1296: 1291: 1283: 1278: 1270: 1268: 1260: 1255: 1247: 1242: 1234: 1229: 1221: 1216: 1208: 1207:MichiganFlora: 1206: 1198: 1193: 1185: 1180: 1172: 1167: 1159: 1154: 1146: 1141: 1133: 1128: 1120: 1115: 1107: 1102: 1094: 1089: 1081: 1076: 1068: 1063: 1055: 1053: 1045: 1043: 1034: 1033: 1028: 1019: 1018: 1013: 1000: 990: 989: 979: 977: 972: 971: 967: 957: 955: 950: 949: 945: 940: 936: 916: 912: 901:L. (May-apple)" 894: 893: 886: 875: 871: 859: 858: 854: 847: 831: 830: 826: 817: 813: 804: 802: 797: 796: 792: 783: 779: 766: 762: 752: 750: 743: 738: 737: 733: 724: 722: 713: 712: 708: 699: 698: 694: 683: 679: 672: 668: 651: 650: 646: 637: 635: 629: 628: 624: 614: 612: 590: 589: 585: 574: 570: 560: 558: 544: 543: 539: 534: 530: 525: 518: 512: 503: 497: 488: 482: 473: 467: 458: 452: 443: 381:podophyllotoxin 376: 348:may apple borer 333:Podophyllotoxin 311:) is used as a 305:podophyllotoxin 248:perennial plant 211: 206: 200: 187: 86: 78: 69: 65: 58: 17: 12: 11: 5: 1451: 1449: 1441: 1440: 1435: 1430: 1425: 1420: 1415: 1410: 1405: 1395: 1394: 1388: 1387: 1385: 1384: 1380:wfo-0000397408 1371: 1361: 1351: 1341: 1328: 1315: 1302: 1289: 1276: 1266: 1253: 1240: 1227: 1214: 1204: 1191: 1178: 1165: 1152: 1139: 1126: 1113: 1100: 1087: 1074: 1061: 1051: 1041: 1026: 1010: 1008: 1002: 1001: 996: 988: 987: 965: 943: 934: 910: 884: 869: 852: 845: 824: 811: 790: 777: 760: 731: 706: 692: 677: 666: 655:Podophyllum L. 644: 622: 583: 568: 537: 527: 526: 524: 521: 520: 519: 513: 506: 504: 498: 491: 489: 483: 476: 474: 468: 461: 459: 453: 446: 442: 439: 375: 372: 325:salicylic acid 250:in the family 234: 233: 232: 231: 220: 219: 213: 212: 207: 196: 195: 189: 188: 181: 179: 175: 174: 167: 163: 162: 157: 153: 152: 147: 143: 142: 137: 130: 129: 124: 117: 116: 111: 104: 103: 98: 94: 93: 80: 79: 63: 60: 59: 54: 51: 50: 44: 43: 35: 34: 26: 25: 15: 13: 10: 9: 6: 4: 3: 2: 1450: 1439: 1436: 1434: 1431: 1429: 1426: 1424: 1421: 1419: 1416: 1414: 1411: 1409: 1408:Berberidaceae 1406: 1404: 1401: 1400: 1398: 1381: 1376: 1372: 1368: 1362: 1358: 1352: 1348: 1342: 1338: 1333: 1329: 1325: 1320: 1316: 1312: 1307: 1303: 1299: 1294: 1290: 1286: 1281: 1277: 1273: 1267: 1263: 1258: 1254: 1250: 1245: 1241: 1237: 1232: 1228: 1224: 1219: 1215: 1211: 1205: 1201: 1196: 1192: 1188: 1183: 1179: 1175: 1170: 1166: 1162: 1157: 1153: 1149: 1144: 1140: 1136: 1131: 1127: 1123: 1118: 1114: 1110: 1105: 1101: 1097: 1092: 1088: 1084: 1079: 1075: 1071: 1066: 1062: 1058: 1052: 1048: 1042: 1037: 1031: 1027: 1022: 1016: 1012: 1011: 1009: 1007: 1003: 999: 994: 975: 969: 966: 953: 947: 944: 938: 935: 932: 928: 924: 920: 914: 911: 906: 902: 900: 891: 889: 885: 881: 880: 873: 870: 865: 864: 856: 853: 848: 846:0-394-50432-1 842: 838: 834: 828: 825: 821: 815: 812: 800: 794: 791: 787: 781: 778: 775: 771: 770: 764: 761: 749: 742: 735: 732: 721: 717: 710: 707: 702: 696: 693: 690: 688: 681: 678: 675: 670: 667: 662: 658: 656: 648: 645: 634: 633: 626: 623: 611: 607: 603: 602: 597: 595: 587: 584: 581: 579: 572: 569: 556: 552: 550: 541: 538: 532: 529: 522: 516: 510: 505: 501: 495: 490: 486: 480: 475: 471: 465: 460: 456: 450: 445: 440: 438: 436: 432: 428: 424: 420: 416: 411: 409: 405: 401: 400:antihelmintic 397: 393: 389: 384: 382: 373: 371: 369: 368: 364: 359: 354: 351: 349: 345: 341: 336: 334: 330: 326: 322: 318: 314: 310: 306: 301: 298: 296: 292: 288: 284: 280: 275: 273: 269: 268:wild mandrake 265: 261: 257: 253: 252:Berberidaceae 249: 246: 242: 241: 227: 224: 223: 221: 218: 214: 210: 205: 203: 197: 194: 193:Binomial name 190: 186: 185: 180: 177: 176: 173: 172: 168: 165: 164: 161: 160:Berberidaceae 158: 155: 154: 151: 148: 145: 144: 141: 138: 135: 132: 131: 128: 125: 122: 119: 118: 115: 114:Tracheophytes 112: 109: 106: 105: 102: 99: 96: 95: 90: 85: 81: 75: 61: 57: 52: 49: 45: 41: 36: 32: 27: 22: 19: 1005: 980:22 September 978:. 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Retrieved 554: 548: 540: 531: 514: 499: 484: 469: 454: 412: 385: 377: 365: 355: 352: 337: 329:plantar wart 302: 299: 276: 272:ground lemon 271: 267: 263: 259: 256:common names 239: 238: 237: 225: 201: 199: 183: 182: 170: 150:Ranunculales 133: 120: 107: 47: 18: 1285:kew-2412818 1231:NatureServe 1156:iNaturalist 1030:Wikispecies 921:, chapter: 687:Podophyllum 515:P. peltatum 500:P. peltatum 485:P. peltatum 470:P. peltatum 455:P. peltatum 358:mycorrhizae 309:podophyllin 171:Podophyllum 127:Angiosperms 74:NatureServe 1397:Categories 1364:WisFlora: 1280:Plant List 805:2013-03-16 725:2020-04-25 523:References 427:teniposide 419:escharotic 321:Posalfilin 317:cytostatic 245:herbaceous 1122:233500972 974:"PubChem" 714:PubChem. 423:etoposide 415:topically 396:cathartic 315:and as a 313:purgative 178:Species: 97:Kingdom: 24:Mayapple 1354:VASCAN: 1332:Tropicos 1269:PalDat: 1236:2.157183 1187:10584599 1174:107599-1 1021:Q1572090 1015:Wikidata 689:Linnaeus 638:28 March 615:28 March 561:26 April 408:settlers 346:and the 279:colonies 260:mayapple 217:Synonyms 156:Family: 140:Eudicots 1337:3500162 1218:MoBotPF 1135:3033839 441:Gallery 431:cancers 287:rhizome 166:Genus: 146:Order: 101:Plantae 72: ( 70:Secure 1347:447954 1344:uBio: 1293:PLANTS 1262:928422 1223:277777 1096:596250 1070:121594 1044:AoFP: 929:  843:  517:flower 502:flower 417:as an 398:, and 392:emetic 390:as an 291:flower 283:leaves 270:, and 254:. Its 243:is an 229:Moench 1324:13375 1249:35933 1200:18850 1182:IRMNG 1161:49288 1148:29138 1109:PDLPE 1083:4KR3V 1054:APA: 820:FUNGI 744:(PDF) 487:fruit 472:fruit 457:fruit 295:fruit 134:Clade 121:Clade 108:Clade 1367:4553 1357:3672 1306:POWO 1298:POPE 1244:NCBI 1195:ITIS 1169:IPNI 1143:GRIN 1130:GBIF 1104:EPPO 1065:BOLD 1057:1146 1047:3636 982:2022 960:2022 927:ISBN 841:ISBN 755:2019 640:2015 617:2015 563:2024 425:and 363:rust 258:are 1375:WFO 1319:RHS 1210:546 1117:FNA 1091:EoL 1078:CoL 772:at 307:or 293:or 1399:: 1377:: 1334:: 1321:: 1308:: 1295:: 1282:: 1259:: 1246:: 1233:: 1220:: 1197:: 1184:: 1171:: 1158:: 1145:: 1132:: 1119:: 1106:: 1093:: 1080:: 1067:: 1032:: 1017:: 903:, 887:^ 746:. 718:. 659:. 608:, 604:. 598:. 580:L. 553:. 410:. 394:, 350:. 331:. 319:. 266:, 262:, 209:L. 136:: 123:: 110:: 984:. 962:. 897:" 849:. 808:. 757:. 728:. 663:. 657:" 653:" 619:. 596:" 592:" 565:. 551:" 547:" 76:)

Index



Conservation status
NatureServe
Scientific classification
Edit this classification
Plantae
Tracheophytes
Angiosperms
Eudicots
Ranunculales
Berberidaceae
Podophyllum
Binomial name
L.
Synonyms
herbaceous
perennial plant
Berberidaceae
common names
colonies
leaves
rhizome
flower
fruit
podophyllotoxin
podophyllin
purgative
cytostatic
Posalfilin

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