Knowledge (XXG)

Ponezumab

Source 📝

1012: 955: 372: 365: 358: 78: 238: 1057: 996: 1091: 1086: 34: 1076: 1050: 989: 914: 324: 307:
Popescu CD, Trofin D, Ignat B, Matei D (2014). "New Aspects of Therapeutic Management in Alzheimer`s Disease". In Atta-ur-Rahman (ed.).
1101: 1096: 1081: 1043: 982: 350: 445: 293: 135: 931: 381: 570: 565: 919: 826: 259: 1019: 962: 99: 44: 27: 269:
Inc. In November 2011 Pfizer halted the development of ponezumab after finishing a phase 2 trial.
802: 704: 603: 474: 320: 1027: 966: 108: 611: 312: 180: 1011: 286: 144: 1023: 925: 580: 1070: 896: 855: 665: 499: 891: 782: 777: 762: 719: 660: 650: 635: 630: 316: 66: 340: 875: 841: 807: 797: 772: 675: 670: 625: 620: 616: 593: 544: 504: 431: 954: 870: 787: 767: 746: 741: 709: 645: 640: 534: 529: 519: 514: 509: 494: 489: 460: 426: 219: 119: 812: 736: 724: 714: 689: 655: 588: 549: 539: 524: 410: 405: 49: 287:"Statement On A Nonproprietary Name Adopted By The USAN Council: Ponezumab" 20: 731: 61: 266: 164: 53: 258:
is a humanized monoclonal antibody designed for the treatment of
390: 311:. Vol. 3. Sharjah: Bentham Science Publishers. p. 55. 155: 354: 384:
for bone, musculoskeletal, circulatory, and neurologic systems
309:
Frontiers in Clinical Drug Research: Alzheimer Disorders
1031: 970: 245: 884: 863: 854: 834: 825: 755: 697: 688: 602: 579: 558: 482: 473: 453: 444: 419: 398: 389: 218: 179: 174: 154: 134: 118: 98: 93: 77: 72: 60: 43: 33: 26: 107: 1051: 990: 366: 8: 19: 1058: 1044: 997: 983: 860: 831: 694: 479: 450: 395: 373: 359: 351: 143: 278: 18: 7: 1008: 1006: 951: 949: 163: 1092:Experimental monoclonal antibodies 1087:Anti-amyloid monoclonal antibodies 1030:. You can help Knowledge (XXG) by 969:. You can help Knowledge (XXG) by 14: 1010: 953: 197: 191: 1077:Drugs not assigned an ATC code 317:10.2174/9781681080680115030004 209: 203: 185: 1: 294:American Medical Association 265:Ponezumab was developed by 1118: 1005: 948: 175:Chemical and physical data 1102:Nervous system drug stubs 1097:Monoclonal antibody stubs 1082:Drugs developed by Pfizer 909: 235: 1022:article relating to the 965:–related article is a 827:Angiogenesis inhibitor 963:monoclonal antibody 260:Alzheimer's disease 28:Monoclonal antibody 23: 16:Monoclonal antibody 936:Never to phase III 705:Anti-amyloid drugs 1039: 1038: 978: 977: 946: 945: 905: 904: 850: 849: 821: 820: 684: 683: 469: 468: 440: 439: 326:978-1-68108-068-0 253: 252: 1109: 1060: 1053: 1046: 1014: 1007: 999: 992: 985: 957: 950: 861: 832: 695: 612:Alacizumab pegol 480: 451: 396: 375: 368: 361: 352: 345: 344: 337: 331: 330: 304: 298: 297: 291: 283: 249: 248: 241: 230: 228: 211: 205: 199: 193: 187: 167: 147: 111: 24: 22: 1117: 1116: 1112: 1111: 1110: 1108: 1107: 1106: 1067: 1066: 1065: 1064: 1004: 1003: 947: 942: 941: 926:Clinical trials 901: 880: 846: 817: 751: 680: 598: 575: 554: 465: 446:Musculoskeletal 436: 415: 385: 379: 349: 348: 339: 338: 334: 327: 306: 305: 301: 289: 285: 284: 280: 275: 244: 242: 239:(what is this?) 236: 226: 224: 214: 208: 202: 196: 190: 170: 150: 130: 114: 89: 17: 12: 11: 5: 1115: 1113: 1105: 1104: 1099: 1094: 1089: 1084: 1079: 1069: 1068: 1063: 1062: 1055: 1048: 1040: 1037: 1036: 1024:nervous system 1015: 1002: 1001: 994: 987: 979: 976: 975: 958: 944: 943: 940: 939: 938: 937: 934: 923: 917: 911: 910: 907: 906: 903: 902: 900: 899: 894: 888: 886: 882: 881: 879: 878: 873: 867: 865: 858: 852: 851: 848: 847: 845: 844: 838: 836: 829: 823: 822: 819: 818: 816: 815: 810: 805: 800: 795: 790: 785: 780: 775: 770: 765: 759: 757: 753: 752: 750: 749: 744: 739: 734: 729: 728: 727: 722: 717: 712: 701: 699: 692: 686: 685: 682: 681: 679: 678: 673: 668: 663: 658: 653: 648: 643: 638: 633: 628: 623: 614: 608: 606: 600: 599: 597: 596: 591: 585: 583: 577: 576: 574: 573: 568: 562: 560: 556: 555: 553: 552: 547: 542: 537: 532: 527: 522: 517: 512: 507: 502: 497: 492: 486: 484: 477: 471: 470: 467: 466: 464: 463: 457: 455: 448: 442: 441: 438: 437: 435: 434: 429: 423: 421: 417: 416: 414: 413: 408: 402: 400: 393: 387: 386: 380: 378: 377: 370: 363: 355: 347: 346: 332: 325: 299: 277: 276: 274: 271: 251: 250: 233: 232: 222: 216: 215: 212: 206: 200: 194: 188: 183: 177: 176: 172: 171: 169: 168: 160: 158: 152: 151: 149: 148: 140: 138: 132: 131: 129: 128: 124: 122: 116: 115: 113: 112: 104: 102: 96: 95: 91: 90: 88: 87: 83: 81: 75: 74: 70: 69: 64: 58: 57: 47: 41: 40: 39:Whole antibody 37: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 1114: 1103: 1100: 1098: 1095: 1093: 1090: 1088: 1085: 1083: 1080: 1078: 1075: 1074: 1072: 1061: 1056: 1054: 1049: 1047: 1042: 1041: 1035: 1033: 1029: 1025: 1021: 1016: 1013: 1009: 1000: 995: 993: 988: 986: 981: 980: 974: 972: 968: 964: 959: 956: 952: 935: 933: 930: 929: 927: 924: 921: 918: 916: 913: 912: 908: 898: 897:Landogrozumab 895: 893: 890: 889: 887: 883: 877: 874: 872: 869: 868: 866: 862: 859: 857: 856:Growth factor 853: 843: 840: 839: 837: 833: 830: 828: 824: 814: 811: 809: 806: 804: 801: 799: 796: 794: 791: 789: 786: 784: 781: 779: 776: 774: 771: 769: 766: 764: 761: 760: 758: 754: 748: 745: 743: 740: 738: 735: 733: 730: 726: 723: 721: 718: 716: 713: 711: 708: 707: 706: 703: 702: 700: 696: 693: 691: 687: 677: 674: 672: 669: 667: 666:Ralpancizumab 664: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 632: 629: 627: 624: 622: 618: 615: 613: 610: 609: 607: 605: 601: 595: 592: 590: 587: 586: 584: 582: 578: 572: 569: 567: 564: 563: 561: 557: 551: 548: 546: 543: 541: 538: 536: 533: 531: 528: 526: 523: 521: 518: 516: 513: 511: 508: 506: 503: 501: 500:Ascrinvacumab 498: 496: 493: 491: 488: 487: 485: 481: 478: 476: 472: 462: 459: 458: 456: 452: 449: 447: 443: 433: 430: 428: 425: 424: 422: 418: 412: 409: 407: 404: 403: 401: 397: 394: 392: 388: 383: 376: 371: 369: 364: 362: 357: 356: 353: 342: 336: 333: 328: 322: 318: 314: 310: 303: 300: 295: 288: 282: 279: 272: 270: 268: 263: 261: 257: 247: 240: 234: 223: 221: 217: 184: 182: 178: 173: 166: 162: 161: 159: 157: 153: 146: 142: 141: 139: 137: 133: 126: 125: 123: 121: 117: 110: 106: 105: 103: 101: 97: 92: 85: 84: 82: 80: 76: 73:Clinical data 71: 68: 65: 63: 59: 55: 51: 48: 46: 42: 38: 36: 32: 29: 25: 1032:expanding it 1017: 971:expanding it 960: 892:Domagrozumab 792: 783:Galcanezumab 778:Fremanezumab 763:Bapineuzumab 720:Gantenerumab 661:Idarucizumab 651:Etaracizumab 636:Caplacizumab 631:Brolucizumab 335: 308: 302: 281: 264: 255: 254: 243:   237:   109:1178862-65-1 67:beta-amyloid 922:from market 876:Trevogrumab 842:Ranibizumab 808:Solanezumab 803:Semorinemab 798:Refanezumab 773:Eptinezumab 676:Vanucizumab 671:Tadocizumab 626:Bococizumab 621:Ranibizumab 617:Bevacizumab 594:Volociximab 545:Ramucirumab 505:Bentracimab 475:Circulatory 432:Romosozumab 382:Monoclonals 231: g·mol 94:Identifiers 1071:Categories 871:Bimagrumab 788:Ozanezumab 768:Crenezumab 747:Opicinumab 742:Fulranumab 710:Aducanumab 690:Neurologic 646:Emicizumab 641:Demcizumab 535:Nesvacumab 530:Inclacumab 520:Evolocumab 515:Evinacumab 510:Enoticumab 495:Alirocumab 490:Abelacimab 461:Stamulumab 427:Blosozumab 341:"Alzforum" 273:References 220:Molar mass 145:1TG15H1XE9 120:ChemSpider 100:CAS Number 932:Phase III 920:Withdrawn 885:Humanized 835:Humanized 813:Tanezumab 793:Ponezumab 756:Humanized 737:Fasinumab 725:Lecanemab 715:Donanemab 656:Faricimab 604:Humanized 589:Abciximab 571:Imciromab 566:Biciromab 550:Rinucumab 540:Orticumab 525:Icrucumab 420:Humanized 411:Denosumab 406:Burosumab 256:Ponezumab 50:Humanized 21:Ponezumab 732:Erenumab 581:Chimeric 246:(verify) 79:ATC code 181:Formula 915:WHO-EM 323:  267:Pfizer 165:D09952 62:Target 52:(from 45:Source 1026:is a 1018:This 961:This 864:Human 698:Human 559:Mouse 483:Human 454:Human 399:Human 290:(PDF) 195:10158 54:mouse 1028:stub 1020:drug 967:stub 391:Bone 321:ISBN 207:2090 201:1730 189:6552 156:KEGG 136:UNII 127:none 86:none 35:Type 313:doi 229:.48 227:272 225:148 1073:: 928:: 319:. 292:. 262:. 213:52 1059:e 1052:t 1045:v 1034:. 998:e 991:t 984:v 973:. 619:/ 374:e 367:t 360:v 343:. 329:. 315:: 296:. 210:S 204:O 198:N 192:H 186:C 56:)

Index

Monoclonal antibody
Type
Source
Humanized
mouse
Target
beta-amyloid
ATC code
CAS Number
1178862-65-1
ChemSpider
UNII
1TG15H1XE9
KEGG
D09952
Formula
Molar mass
(what is this?)
(verify)
Alzheimer's disease
Pfizer
"Statement On A Nonproprietary Name Adopted By The USAN Council: Ponezumab"
American Medical Association
doi
10.2174/9781681080680115030004
ISBN
978-1-68108-068-0
"Alzforum"
v
t

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.