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in 1854. The class of chemical compounds to which it belongs is thus called the cinchona alkaloids. Bark extracts had been used to treat malaria since at least 1632 and it was introduced to Spain as early as 1636 by
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113:. While it is unclear if use during pregnancy carries potential for fetal harm, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an
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146:. Treatment of malaria with quinine marks the first known use of a chemical compound to treat an infectious disease. (
81:. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in
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Quinine was first isolated in 1820 from the bark of a
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37:Cinchona, the plant quinine was derived from
69:is not available. While sometimes used for
89:Common side effects include headache,
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97:. More severe side effects include
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109:. Use can make one more prone to
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77:. It can be taken by mouth or
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18:Portal:Drink
83:tonic water
63:chloroquine
67:artesunate
53:babesiosis
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123:cinchona
115:alkaloid
99:deafness
95:sweating
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49:malaria
44:Quinine
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