125:(central area of the retina) is scanned with a succession of stimuli, each stimulus consisting of a series of dots arranged along a vertical or horizontal axis. In each stimulus, a small number of dots are misaligned, thereby creating an artificial distortion (bump or wave). The examinee's task is to perceive these artificial distortions and mark their locations on the visual field. When a stimulus is projected on a healthy portion of the retina, the examinee identifies the artificial distortion and is likely to mark a correct location. If the stimulus is projected on a damaged region of the retina, a pathological distortion may be perceived instead of the artificial distortion, especially if the pathological distortion is more prominent than the artificial distortion. The examinee may then mark a location that is distant from the artificial distortion, indicating that a pathological distortion may have been perceived. By manipulating the amplitude of artificial distortions, the amplitude of the pathology in the area of interest can be quantified. At the end of test, comparison of the set of erroneous responses against a normative data base is used to determine if test results are within normal limits.
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88:, patients with small and peripheral defects in their vision are often unaware of such changes until late stages in the disease. Another problem is that minute visual aberrations can be normal and therefore should be distinguished from genuine visual abnormalities. Preferential hyperacuity perimetry (PHP) is a technology that bypasses filling-in and quantifies the extent of visual abnormalities.
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108:, the ability to separate between distinct objects. Therefore, in retinal diseases such as macular degeneration responses to hyperacuity stimuli may be abnormal long before any changes in visual acuity are observed. Another key element in PHP technology relies on the competition principle. According to this principle, visual attention is
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Goldstein M, Loewenstein A, Barak A, Pollack A, Bukelman A, Katz H, Springer A, Schahat AP, Bressler NM, Bressler SB, Conney MJ, Alster Y, Rafaeli O, Malach R (April–May 2005). ""Results of a multicenter clinical trial to evaluate the preferential hyperacuity perimeter for detection of age-related
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may be irreversibly damaged. Hence, if not treated, macular degeneration may lead to blindness. Awareness to early changes in vision, especially in high risk patients, leads to early treatment (such as intravitreal injection of anti-VEGF factors, e.g.
112:
attracted to the larger object. When two stimuli, which are different in size, are simultaneously and briefly displayed, the observer is more likely to perceive the larger of the two, while missing the other.
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Loewenstein A. (September 2007). "The significance of early detection of age-related macular degeneration: Richard & Hinda
Rosenthal Foundation lecture".
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Achard OD, Safran AB, Duret FC, Ragama E (September 1995). "Role of the completion phenomenon in the evaluation of Amsler grid results".
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104:—the ability to identify the misalignment of visual objects. Visual hyperacuity is at least 10 times more sensitive than
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43:) is a psychophysical test used to identify and quantify visual abnormalities such as
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Westheimer G. (August 1975). ""Editorial: Visual acuity and hyperacuity"".
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84:) and prevents loss of vision. Because of complex brain mechanisms such as
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Vision abnormalities such as metamorphopsia (distortions) and
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592:Reproductive endocrinology and infertility
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30:identify and quantify visual abnormalities
933:Bachelor of Medicine, Bachelor of Surgery
67:are symptoms of retinal diseases such as
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18:
71:. In advanced stages of the disease,
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1071:
832:Physical medicine and rehabilitation
1081:
968:Medical Scientist Training Program
37:Preferential hyperacuity perimetry
22:Preferential hyperacuity perimetry
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1100:
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235:10.1097/00006982-200504000-00008
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958:Doctor of Osteopathic Medicine
392:Oral and maxillofacial surgery
96:PHP takes advantage of visual
1:
199:10.1016/s0002-9394(14)72162-2
938:Bachelor of Medical Sciences
705:Neurosurgical anesthesiology
156:10.1097/IAE.0b013e318050d2ec
1153:
1056:
892:Transplantation medicine
783:Clinical neurophysiology
700:Obstetric anesthesiology
620:Interventional radiology
380:Digestive system surgery
221:macular degeneration"".
763:Intensive care medicine
737:Mass gathering medicine
582:Maternal–fetal medicine
355:Cardiothoracic surgery
1006:Personalized medicine
865:Reproductive medicine
790:Occupational medicine
744:Evolutionary medicine
1026:Traditional medicine
986:Alternative medicine
853:Addiction psychiatry
667:Transfusion medicine
662:Medical microbiology
577:Gynecologic oncology
429:Reproductive surgery
69:macular degeneration
1048:History of medicine
1031:Veterinary medicine
838:Preventive medicine
690:Adolescent medicine
532:Infectious diseases
121:In a PHP test, the
73:photoreceptor cells
51:. It is a type of
16:Psychophysical test
996:Molecular oncology
953:Doctor of Medicine
943:Master of Medicine
860:Radiation oncology
732:Emergency medicine
685:Addiction medicine
652:Clinical chemistry
647:Clinical pathology
439:Transplant surgery
397:Orthopedic surgery
375:Colorectal surgery
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948:Master of Surgery
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897:Tropical medicine
843:Prison healthcare
758:Hospital medicine
722:Disaster medicine
712:Aviation medicine
527:Hospital medicine
434:Surgical oncology
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805:Pain management
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727:Diving medicine
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387:Neurosurgery
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875:Venereology
820:Neonatology
717:Dermatology
572:Gynaecology
564:gynaecology
547:Pulmonology
365:Eye surgery
327:Specialties
98:hyperacuity
82:ranibizumab
78:bevacizumab
1121:Categories
848:Psychiatry
834:(PM&R)
827:Phlebology
815:Pediatrics
642:Anatomical
607:Diagnostic
587:Obstetrics
537:Nephrology
522:Hematology
517:Geriatrics
510:Hepatology
495:Cardiology
485:Immunology
129:References
110:preferably
92:Technology
86:filling-in
59:Background
1137:Optometry
1036:Physician
920:education
778:Neurology
773:Narcology
637:Pathology
615:Radiology
490:Angiology
454:Andrology
53:perimetry
1066:Category
542:Oncology
473:medicine
471:Internal
319:Medicine
251:13711267
243:15805906
164:17891011
117:PHP test
1106:Outline
1076:Commons
1021:Therapy
918:Medical
481:Allergy
449:Urology
342:Surgery
278:1150397
207:7661204
172:2408306
65:scotoma
49:scotoma
27:Purpose
1096:Portal
963:MD–PhD
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223:Retina
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144:Retina
123:macula
678:Other
247:S2CID
168:S2CID
274:PMID
239:PMID
203:PMID
160:PMID
47:and
412:ENT
330:and
231:doi
195:doi
191:120
152:doi
80:or
41:PHP
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