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Cutibacterium acnes

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are related to treating acne-related issues. This issue often develops during hormonal periods; however, it is also apparent through early adulthood. There are no quantitative differences between C. acnes of the skin of patients with acne, but the C. acnes phylogenetic groups display distinct genetic and phenotypic characteristics. C. acnes
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by which salicylic acid (SA) treats acne vulgaris. A study finds that SA suppresses the AMPK/SREBP1 (AMP-activated protein kinase)(AMPK/SREBP1 pathway is a signaling pathway involved in the regulation of lipid metabolism in sebocytes, which are the cells responsible for producing sebum in the skin)
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infection. Cutibacterium acnes is one of the most common and universal skin diseases, affecting more than 45 million individuals in the United States. It is one of the most prominent skin diseases, affecting more than 45 million individuals yearly within the country. 20% of all dermatologist visits
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In addition to contributing to skin inflammation and acne lesions, an imbalance in these bacteria may also impair the skin's ability to heal and regenerate, leading to prolonged and more severe acne outbreaks. This disruption can also affect the skin's overall microbiome diversity, potentially
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bacteria secrete many proteins, including several digestive enzymes. These enzymes are involved in the digestion of sebum and the acquisition of other nutrients. They can also destabilize the layers of cells that form the walls of the follicle. The cellular damage, metabolic byproducts and
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Ross JI, Snelling AM, Eady EA, Cove JH, Cunliffe WJ, Leyden JJ, et al. (February 2001). "Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia".
981:"The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov" 463:
starts to colonize on the skin around 1 to 3 years prior to puberty and grows exponentially during this time. This is why so many teens and young adults struggle with acne. Prescriptions to treat acne are often antibiotics. However, with the rise of
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that cause these infections of otherwise sterile tissues (prior to medical procedures), however, are the same subspecies found on the skin of individuals who do not have acne-prone skin, so are likely local contaminants. Moderate to severe
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Coates P, Vyakrnam S, Eady EA, Jones CE, Cove JH, Cunliffe WJ (May 2002). "Prevalence of antibiotic-resistant propionibacteria on the skin of acne patients: 10-year surveillance data and snapshot distribution study".
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increasing susceptibility to other skin conditions such as eczema or rosacea. Investigating the dynamics of this relationship may offer insights into novel therapeutic approaches for managing various skin disorders.
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Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, which includes the hair follicle, hair shaft, and sebaceous gland and about 650 million people are affected globally by this disease.
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Haidar R., Najjar M., Boghossian A.D., Tabbarah Z., "Propionibacterium acnes causing delayed postoperative spine infection: Review." Scandinavian Journal of Infectious Diseases. 42 (6-7) (pp 405-411), 2010
3759: 835:. These results suggest that SA has a multifaceted approach in treating acne vulgaris by targeting several key factors that contribute to its development. The minimum inhibitory concentration for SA is 822:
is a naturally occurring substance derived from plants (white willow bark and wintergreen leaves) used to promote exfoliation of the skin in order to treat acne. Additionally, research investigates the
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Fu Y, Zu Y, Chen L, Efferth T, Liang H, Liu Z, Liu W (October 2007). "Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy".
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Togsverd-Bo K, Wiegell SR, Wulf HC, Haedersdal M (February 2009). "Short and limited effect of long-pulsed dye laser alone and in combination with photodynamic therapy for inflammatory rosacea".
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Hiramatsu J, Kataoka M, Nakata Y, Okazaki K, Tada S, Tanimoto M, Eishi Y (October 2003). "Propionibacterium acnes DNA detected in bronchoalveolar lavage cells from patients with sarcoidosis".
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have a symbiotic relationship. Both bacteria exist on the normal flora of the skin and a disrupt in balance of these bacteria on the skin can result in acne or other bacterial infection.
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Raman A, Weir U, Bloomfield SF (October 1995). "Antimicrobial effects of tea-tree oil and its major components on Staphylococcus aureus, Staph. epidermidis and Propionibacterium acnes".
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Brüggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, et al. (July 2004). "The complete genome sequence of Propionibacterium acnes, a commensal of human skin".
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bacteria are susceptible to a wide range of antimicrobial molecules, from both pharmaceutical and natural sources. The antibiotics most frequently used to treat acne vulgaris are
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pathway in sebocytes, leading to a decrease in lipid synthesis and sebum production. SA also reduces the inflammatory response of sebocytes and decreases the proliferation of
3752: 2131:"Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy" 1325:
Gilchrist TC (1900). "A bacteriological and microscopical study of over 300 vesicular and pustular lesions of the skin, with a research upon the etiology of acne vulgaris".
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McLean RJ, Hussain AA, Sayer M, Vincent PJ, Hughes DJ, Smith TJ (September 1993). "Antibacterial activity of multilayer silver-copper surface films on catheter material".
402:, cellular debris and metabolic byproducts from the surrounding skin tissue as their primary sources of energy and nutrients. Elevated production of sebum by hyperactive 307:
present on most healthy adult humans' skin. It is usually just barely detectable on the skin of healthy preadolescents. It lives, among other things, primarily on
4517: 3745: 4556: 509:, amongst other bacterial contaminants. Whether this is a root causality, just opportunistic and a side effect, or a more complex pathological duality between 4210: 1607:
Kim J (2005). "Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses".
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Nisbet, M.; Briggs, S.; Ellis-Pegler, R.; Thomas, M. ;Holland, D. "Propionibacterium acnes: an under-appreciated cause of post-neurosurgical infection"
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Lu J, Cong T, Wen X, Li X, Du D, He G, Jiang X (October 2019). "Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes".
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Lang G, Buchbauer G (January 2012). "A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review".
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Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC, et al. (April 2007). "Guidelines of care for acne vulgaris management".
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is especially sensitive to light in the 405–420 nanometer (near the ultraviolet) range due to an endogenic porphyrin–coporphyrin III. A total
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bacteria represents a growing problem worldwide. The problem is especially pronounced in North America and Europe. The antibiotic families that
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Leyden JJ, Wortzman M, Baldwin EK (December 2008). "Antibiotic-resistant Propionibacterium acnes suppressed by a benzoyl peroxide cleanser 6%".
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Ross JI, Snelling AM, Carnegie E, Coates P, Cunliffe WJ, Bettoli V, et al. (March 2003). "Antibiotic-resistant acne: lessons from Europe".
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Perry A., Lambert P. " Propionibacterium acnes: Infection beyond the skin." Expert Review of Anti-Infective Therapy. 9 (12) (pp 1149-1156), 2011
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Gharamti AA, Kanafani ZA (December 2017). "Cutibacterium (formerly Propionibacterium) acnes infections associated with implantable devices".
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Tuchayi, Sara Moradi; Makrantonaki, Evgenia; Ganceviciene, Ruta; Dessinioti, Clio; Feldman, Steven R.; Zouboulis, Christos C. (2015-09-17).
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Papageorgiou P, Katsambas A, Chu A (May 2000). "Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris".
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Albietz JM, Lenton LM (October 2006). "Effect of antibacterial honey on the ocular flora in tear deficiency and meibomian gland disease".
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in follicles can trigger inflammation. This inflammation can lead to the symptoms associated with some common skin disorders, such as
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structure and DNA G + C content, the cutaneous species was distinguishable from other species that had been previously categorized as
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that is closely related to the human-associated strains. The two lines diverged roughly 7,000 years ago, at about the same time when
4048: 3768: 3702: 468:, antibiotics are now often combined with broad-spectrum antibacterial agents such as benzoyl peroxide, and other medications like 2726:
Tzellos T, Zampeli V, Makrantonaki E, Zouboulis CC (June 2011). "Treating acne with antibiotic-resistant bacterial colonization".
4023: 4612: 4375: 4092: 4082: 3989: 4535: 2207:"Population genetic analysis of Propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne" 1393: 185: 178: 4607: 4355: 4200: 3833: 366: 56: 4341: 4247: 4186: 4112: 171: 4456: 1468: 1420: 3901: 505: 4561: 4232: 4016: 3950: 2705: 1184:"Draft Genome Sequences of Propionibacterium acnes Type Strain ATCC6919 and Antibiotic-Resistant Strain HL411PA1" 4369: 4033: 3847: 3712: 3226:"Chemical composition and biological activities of essential oils extracted from Korean endemic citrus species" 3158:"The antibacterial activity of clove essential oil against Propionibacterium acnes and its mechanism of action" 698: 465: 360: 4271: 4257: 4038: 3867: 3809: 3339:
Libenson L, Hadley FP, Mcilroy AP, Wetzel VM, Mellon RR (1953). "Antibacterial effect of elemental sulfur".
2953: 752: 607: 490: 2072:"Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy" 4418: 4264: 4218: 4166: 4131: 4043: 3994: 3963: 3938: 647: 623: 619: 579: 320: 586:
and is associated with disease activity, but it can also be found in 23% of controls. The subspecies of
4400: 4303: 4243: 4177: 4156: 4138: 4121: 495: 407: 141: 1469:"Cutibacterium (Formerly Propionibacterium) avidum: A Rare but Avid Agent of Prosthetic Hip Infection" 4571: 4478: 4064: 4028: 4006: 3858: 3825: 3798: 3469: 2547: 2218: 2083: 1240: 1039:"Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates" 108: 3737: 4299: 4194: 4097: 4077: 3984: 3906: 3818: 3708: 3654:"Interkingdom transfer of the acne-causing agent, Propionibacterium acnes, from human to grapevine" 875: 655: 269: 98: 3724: 3225: 3021:"Efficacy of chlorhexidine gluconate ointment (Oronine H(®)) for experimentally-induced comedones" 4391: 4307: 4144: 4087: 3974: 3583: 3540: 3434: 3280: 3138: 3095: 2908: 2864: 2813: 2779: 2751: 2504: 2377:
Emery DC, Shoemark DK, Batstone TE, Waterfall CM, Coghill JA, Cerajewska TL, et al. (2017).
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Capoor MN, Ruzicka F, Schmitz JE, James GA, Machackova T, Jancalek R, et al. (2017-04-03).
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was taxonomically reclassified as a result of biochemical and genomic studies. In terms of both
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Holland C, Mak TN, Zimny-Arndt U, Schmid M, Meyer TF, Jungblut PR, Brüggemann H (August 2010).
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bacteria, including quinolones, cephalosporins, pleuromutilins, penicillins, and sulfonamides.
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Campisano A, Ometto L, Compant S, Pancher M, Antonielli L, Yousaf S, et al. (May 2014).
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Yamakoshi T, Makino T, Matsunaga K, Yoshihisa Y, Rehman MU, Seki T, et al. (July 2012).
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and the associated inflammation make the affected tissue more susceptible to colonization by
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Perry A, Lambert P (December 2011). "Propionibacterium acnes: infection beyond the skin".
615: 541: 443: 403: 265: 1789: 1711:"Recent advances in understanding Propionibacterium acnes ( Cutibacterium acnes) in acne" 3473: 2222: 2087: 1685: 1244: 43: 3979: 3780: 3772: 3629: 3602: 3492: 3453: 3268: 3126: 3047: 3020: 2456: 2429: 2405: 2378: 2288:"Propionibacterium acnes postoperative shoulder arthritis: an emerging clinical entity" 2241: 2206: 2155: 2130: 2106: 2071: 1992: 1967: 1943: 1908: 1663: 1584: 1557: 1534: 1208: 1183: 819: 748: 631: 564: 472:(commonly known as Accutane) are being used on patients with severe or resistant acne. 335: 78: 17: 2682: 2657: 2633: 2609:"Antimicrobiol susceptibility of Propinibacterium acnes and related microbial species" 2608: 2430:"Propionibacterium acnes: an underestimated pathogen in implant-associated infections" 1370: 1345: 4601: 3969: 3891: 3804: 3571: 3528: 3438: 2981: 2896: 2844: 2793: 2508: 2345: 2328: 1836: 1159: 1150: 1134: 789:
has also been shown to have some antibacterial properties that may be active against
770: 744: 592: 549: 430: 316: 293: 257: 246: 118: 88: 3587: 3284: 3099: 2868: 2817: 2755: 2056: 1860: 1636: 1311: 1268: 394:, although they are also found on the surface of healthy skin. In these follicles, 4548: 4290: 4224: 3928: 3915: 3544: 3142: 2912: 2286:
Levy PY, Fenollar F, Stein A, Borrione F, Cohen E, Lebail B, Raoult D (June 2008).
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Vanity, Vitality, and Virility: The Chemistry Behind the Products You Love to Buy
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was created for the cutaneous species, including those formerly identified as
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Liu J, Cheng A, Bangayan NJ, Barnard E, Curd E, Craft N, Li H (August 2014).
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Ross; et al. (2003). "Antibiotic-resistant acne: lessons from Europe".
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bacteria are susceptible to many types of antimicrobial chemicals found in
3697: 3603:"Current evidence and applications of photodynamic therapy in dermatology" 3452:
Blaskovich MA, Elliott AG, Kavanagh AM, Ramu S, Cooper MA (October 2019).
3395: 3134: 3083: 2446: 1558:"Proteomic identification of secreted proteins of Propionibacterium acnes" 815:
Some other antimicrobials like salicylic acid have been proven to inhibit
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Fournière M, Latire T, Souak D, Feuilloley MG, Bedoux G (November 2020).
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have also been demonstrated to be toxic towards many bacteria, including
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3037: 1983: 1917:: Two Major Sentinels of Skin Microbiota and the Influence of Cosmetics" 4496: 4470: 4465: 4073: 1295: 1065: 439: 289: 4509: 3458:
Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria"
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species is not known. Current research has pointed to the idea that
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are also found much more frequently in acne and can induce distinct
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Several naturally occurring molecules and compounds are toxic to
685:. Several other families of antibiotics are also active against 499:. Preliminary research shows healthy pores are only colonized by 2954:"Q&A for Health Care Professionals: Health Care Antiseptics" 1398:
Shoulder Arthritis / Rotator Cuff Tears: causes of shoulder pain
634:(synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome, 503:, while unhealthy ones universally include the nonpore-resident 285: 277: 253: 4483: 4416: 3741: 3560:
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433:. Acne vulgaris is the disease most commonly associated with 1419:
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874:. Its photosensitivity can be enhanced by pretreatment with 595:
appears to be more often associated with virulent strains.
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bacteria predominantly live deep within follicles and
2525:. Skincarephysicians.com. 2007-02-16. Archived from 4425: 4390: 4331: 4289: 4242: 4176: 4155: 4120: 4111: 4062: 3899: 3890: 3881: 3857: 3788: 3779: 2428:Portillo ME, Corvec S, Borens O, Trampuz A (2013). 1686:"Understanding Acne - News in Health, January 2010" 1116:Bhatia A, Maisonneuve JF, Persing DH (2004-01-01). 3607:Clinical, Cosmetic and Investigational Dermatology 3025:Clinical, Cosmetic and Investigational Dermatology 2980: 1879:Sarcoidosis, Vasculitis, and Diffuse Lung Diseases 642:. 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Natural 974: 972: 970: 968: 410:) or blockage of the follicle can cause 292:that may be immunogenic (activating the 4054:Extensively drug-resistant tuberculosis 2481:Expert Review of Anti-Infective Therapy 1284:Expert Review of Anti-Infective Therapy 1032: 1030: 1028: 1026: 929: 3840:Arcanobacterium haemolyticum infection 3733:- the Bacterial Diversity Metadatabase 937: 935: 933: 650:brains. It is a common contaminant in 582:of approximately 70% of patients with 319:. It may also be found throughout the 2662:Antimicrobial Agents and Chemotherapy 2613:Antimicrobial Agents and Chemotherapy 2274:Journal of Antimicrobial Chemotherapy 2178:Inoue Y, Suga M (February 2008). 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NOV 2007. 1097-1103.1103. 1664:10.1016/j.clindermatol.2004.03.004 1535:10.1016/j.clindermatol.2004.03.004 735:antibacterial products, including 25: 4049:Multi-drug-resistant tuberculosis 3769:Gram-positive bacterial infection 2958:U.S. Food and Drug Administration 2728:Expert Opinion on Pharmacotherapy 4024:Primary inoculation tuberculosis 3696: 3572:10.1111/j.1468-3083.2008.02781.x 3529:10.1046/j.1365-2133.2000.03481.x 3376:Canadian Journal of Microbiology 2897:10.1046/j.1365-2133.2002.04690.x 2845:10.1046/j.1365-2133.2003.05067.x 2794:10.1046/j.1365-2133.2001.03956.x 2346:10.1111/j.1469-0691.2009.02703.x 1837:10.1046/j.1365-2133.2003.05067.x 1151:10.1128/AAC.45.10.2969-2970.2001 1122:. National Academies Press (US). 374:is an active field of research. 55: 4376:Group JK corynebacterium sepsis 3658:Molecular Biology and Evolution 3115:Letters in Applied Microbiology 2708:. ScienceOfAcne.com. 2011-07-15 2383:Frontiers in Aging Neuroscience 414:bacteria to grow and multiply. 4093:Borderline lepromatous leprosy 4083:Borderline tuberculoid leprosy 3990:Tuberculosis cutis orificialis 1815:British Journal of Dermatology 1748:Nature Reviews Disease Primers 1728:10.12688/f1000research.15659.1 548:. The pathogen may also cause 1: 3199:Flavour and Fragrance Journal 3175:10.1001/archdermatol.2008.549 2987:. Oxford University. p.  2493:10.1080/14787210.2017.1404452 2434:BioMed Research International 1934:10.3390/microorganisms8111752 1327:Johns Hopkins Hospital Report 850:glows orange when exposed to 540:is a common cause of chronic 4356:Corynebacterium minutissimum 4201:Mycobacterium intracellulare 3834:Arcanobacterium haemolyticum 2740:10.1517/14656566.2011.553192 2292:Clinical Infectious Diseases 2232:10.1371/journal.pone.0012277 2097:10.1371/journal.pone.0174518 2033:10.1097/ICL.0000000000000281 662:Antimicrobial susceptibility 367:Propionibacterium granulosum 334:for its ability to generate 260:; it can also cause chronic 4342:Corynebacterium diphtheriae 3601:Wan MT, Lin JY (May 2014). 1473:The Journal of Arthroplasty 4634: 4618:Bacteria described in 1946 3483:10.1038/s41598-019-50746-4 2586:10.1016/j.jaad.2006.08.048 1911:Staphylococcus epidermidis 1485:10.1016/j.arth.2018.02.008 1362:10.1128/JB.52.1.15-23.1946 506:Staphylococcus epidermidis 4017:Papulonecrotic tuberculid 3951:Tuberculous lymphadenitis 2979:Emsley J (July 1, 2004). 2147:10.1007/s00586-013-2675-y 1966:Otto, M (7 August 2009). 1438:10.1016/j.cmi.2018.03.010 453:Comedo acne from C. acnes 326:Originally identified as 201: 194: 167: 162: 147: 140: 52:Scientific classification 50: 41: 34: 4370:Corynebacterium jeikeium 4034:Tuberculous pericarditis 3848:Actinomyces gerencseriae 3713:Medical Subject Headings 3411:Experimental Dermatology 2396:10.3389/fnagi.2017.00195 1575:10.1186/1471-2180-10-230 1200:10.1128/genomeA.00740-14 889:has been found to be an 720:(e.g., clindamycin) and 712:(e.g., erythromycin and 533:Ophthalmic complications 446:to combat against acne. 361:Propionibacterium avidum 4457:Propionibacterium acnes 4039:Urogenital tuberculosis 3868:Propionibacterium acnes 3810:Cutaneous actinomycosis 3727:Propionibacterium acnes 3709:Propionibacterium+acnes 3703:Propionibacterium acnes 3162:Archives of Dermatology 1350:Journal of Bacteriology 1253:10.1126/science.1100330 858:. It is also killed by 753:chlorhexidine gluconate 624:prosthetic heart valves 606:is often considered an 356:Propionibacterium acnes 332:Propionibacterium acnes 299:The species is largely 235:Propionibacterium acnes 215:Propionibacterium acnes 157:Scholz and Kilian, 2016 18:Propionibacterium acnes 4613:Gram-positive bacteria 4044:Tuberculous dactylitis 3995:Tuberculous cellulitis 3353:10.1093/infdis/93.1.28 2135:European Spine Journal 2021:Eye & Contact Lens 1794:emedicine.medscape.com 1688:. Newsinhealth.nih.gov 1652:Clinics in Dermatology 1523:Clinics in Dermatology 1001:10.1099/ijsem.0.001367 949:. DSMZ. Archived from 943:"Genus: Cutibacterium" 608:opportunistic pathogen 599:Opportunistic diseases 580:bronchoalveolar lavage 491:opportunistic bacteria 454: 321:gastrointestinal tract 4401:Gardnerella vaginalis 4304:Nocardia brasiliensis 3671:10.1093/molbev/msu075 3084:10.1055/s-2007-981614 1089:"Genus Cutibacterium" 693:Antibiotic-resistance 626:(predominantly men). 496:Staphylococcus aureus 485:The damage caused by 466:antibiotic resistance 452: 408:sebaceous hyperplasia 330:, it was later named 4007:Lichen scrofulosorum 3859:Propionibacteriaceae 3799:Actinomyces israelii 3705:at Wikimedia Commons 2674:10.1128/aac.11.1.171 2625:10.1128/aac.10.3.387 1760:10.1038/nrdp.2015.29 1188:Genome Announcements 893:of plants. Notably, 699:antibiotic-resistant 513:and this particular 252:(rod) linked to the 109:Propionibacteriaceae 27:Species of bacterium 4608:Propionibacteriales 4549:cutibacterium-acnes 4427:Cutibacterium acnes 4300:Nocardia asteroides 4195:Mycobacterium avium 4098:Lepromatous leprosy 4078:Tuberculoid leprosy 3819:Tropheryma whipplei 3620:10.2147/CCID.S35334 3474:2019NatSR...914658B 3038:10.2147/CCID.S33361 2960:. December 19, 2017 2447:10.1155/2013/804391 2223:2010PLoSO...512277L 2088:2017PLoSO..1274518C 1984:10.1038/nrmicro2182 1915:Cutibacterium acnes 1245:2004Sci...305..671B 887:Cutibacterium acnes 876:aminolevulinic acid 848:Cutibacterium acnes 667:Cutibacterium acnes 656:cerebrospinal fluid 648:Alzheimer's disease 604:Cutibacterium acnes 576:Cutibacterium acnes 561:Cutibacterium acnes 538:Cutibacterium acnes 418:Cutibacterium acnes 388:Cutibacterium acnes 270:intraocular surgery 229:Cutibacterium acnes 151:Cutibacterium acnes 99:Propionibacteriales 36:Cutibacterium acnes 4392:Bifidobacteriaceae 4333:Corynebacteriaceae 4308:Nocardia farcinica 4145:Aquarium granuloma 4088:Borderline leprosy 3975:Erythema induratum 3462:Scientific Reports 3317:10.1093/jac/dkp420 1296:10.1586/eri.11.137 773:such as rosemary, 563:has been found in 455: 4595: 4594: 4580:Open Tree of Life 4419:Taxon identifiers 4410: 4409: 4386: 4385: 4285: 4284: 4281: 4280: 4000:Tuberculous gumma 3883:Corynebacterineae 3877: 3876: 3826:Whipple's disease 3719:Propionibacterium 3701:Media related to 3423:10.1111/exd.13934 2998:978-0-19-280509-6 2487:(12): 1083–1094. 1621:10.1159/000087011 1431:(11): 1149–1155. 1056:10.1111/jdv.15043 1049:(Suppl 2): 5–14. 994:(11): 4422–4432. 953:on 17 August 2018 860:ultraviolet light 697:The emergence of 644:neuroinflammation 622:in patients with 344:phylogenetic tree 225: 224: 219: 211: 16:(Redirected from 4625: 4588: 4587: 4575: 4574: 4565: 4564: 4552: 4551: 4539: 4538: 4526: 4525: 4513: 4512: 4500: 4499: 4487: 4486: 4474: 4473: 4461: 4460: 4459: 4446: 4445: 4444: 4414: 4322:Rhodococcus equi 4118: 3985:Prosector's wart 3897: 3892:Mycobacteriaceae 3888: 3790:Actinomycetaceae 3786: 3762: 3755: 3748: 3739: 3721:(Kenyon College) 3700: 3684: 3683: 3673: 3649: 3643: 3642: 3632: 3622: 3598: 3592: 3591: 3555: 3549: 3548: 3512: 3506: 3505: 3495: 3485: 3449: 3443: 3442: 3406: 3400: 3399: 3371: 3365: 3364: 3336: 3330: 3329: 3319: 3295: 3289: 3288: 3252: 3246: 3245: 3221: 3215: 3214: 3211:10.1002/ffj.2082 3194: 3188: 3187: 3177: 3153: 3147: 3146: 3110: 3104: 3103: 3067: 3061: 3060: 3050: 3040: 3016: 3010: 3009: 3007: 3005: 2986: 2976: 2970: 2969: 2967: 2965: 2950: 2944: 2943: 2923: 2917: 2916: 2879: 2873: 2872: 2828: 2822: 2821: 2787: 2766: 2760: 2759: 2723: 2717: 2716: 2714: 2713: 2702: 2696: 2695: 2685: 2653: 2647: 2646: 2636: 2604: 2598: 2597: 2569: 2563: 2562: 2560: 2559: 2550:. Archived from 2544: 2538: 2537: 2535: 2534: 2519: 2513: 2512: 2476: 2470: 2469: 2459: 2449: 2425: 2419: 2418: 2408: 2398: 2374: 2368: 2365: 2359: 2358: 2348: 2324: 2318: 2317: 2307: 2283: 2277: 2270: 2264: 2261: 2255: 2254: 2244: 2234: 2202: 2196: 2195: 2175: 2169: 2168: 2158: 2126: 2120: 2119: 2109: 2099: 2067: 2061: 2060: 2012: 2006: 2005: 1995: 1963: 1957: 1956: 1946: 1936: 1904: 1895: 1894: 1874: 1865: 1864: 1830: 1810: 1804: 1803: 1801: 1800: 1786: 1780: 1779: 1739: 1733: 1732: 1730: 1706: 1697: 1696: 1694: 1693: 1682: 1676: 1675: 1647: 1641: 1640: 1604: 1598: 1597: 1587: 1577: 1562:BMC Microbiology 1553: 1547: 1546: 1518: 1512: 1511: 1509: 1507: 1479:(7): 2246–2250. 1464: 1458: 1457: 1455: 1453: 1440: 1416: 1410: 1409: 1407: 1405: 1390: 1384: 1383: 1373: 1341: 1335: 1334: 1322: 1316: 1315: 1279: 1273: 1272: 1228: 1222: 1221: 1211: 1194:(4): e00740–14. 1179: 1173: 1172: 1162: 1130: 1124: 1123: 1113: 1104: 1103: 1101: 1099: 1085: 1079: 1078: 1068: 1058: 1034: 1021: 1020: 1018: 1016: 1003: 985: 976: 963: 962: 960: 958: 939: 868:radiant exposure 843:Photosensitivity 769:bacteria. Some 737:benzoyl peroxide 733:over-the-counter 578:can be found in 546:cataract surgery 444:immune responses 404:sebaceous glands 378:Role in diseases 303:and part of the 217: 209: 186:subsp. elongatum 179:subsp. defendens 153: 60: 59: 46: 32: 21: 4633: 4632: 4628: 4627: 4626: 4624: 4623: 4622: 4598: 4597: 4596: 4591: 4583: 4578: 4570: 4568: 4560: 4555: 4547: 4542: 4534: 4529: 4521: 4516: 4508: 4503: 4495: 4490: 4482: 4477: 4469: 4464: 4455: 4454: 4449: 4440: 4439: 4434: 4421: 4411: 4406: 4382: 4327: 4277: 4238: 4172: 4151: 4107: 4103:Histoid leprosy 4058: 3905: 3902:M. tuberculosis 3873: 3853: 3775: 3766: 3725:Type strain of 3693: 3688: 3687: 3651: 3650: 3646: 3600: 3599: 3595: 3557: 3556: 3552: 3514: 3513: 3509: 3451: 3450: 3446: 3408: 3407: 3403: 3388:10.1139/m93-134 3373: 3372: 3368: 3338: 3337: 3333: 3297: 3296: 3292: 3254: 3253: 3249: 3223: 3222: 3218: 3196: 3195: 3191: 3155: 3154: 3150: 3112: 3111: 3107: 3078:(12): 1275–80. 3069: 3068: 3064: 3018: 3017: 3013: 3003: 3001: 2999: 2978: 2977: 2973: 2963: 2961: 2952: 2951: 2947: 2925: 2924: 2920: 2881: 2880: 2876: 2830: 2829: 2825: 2768: 2767: 2763: 2725: 2724: 2720: 2711: 2709: 2704: 2703: 2699: 2655: 2654: 2650: 2606: 2605: 2601: 2571: 2570: 2566: 2557: 2555: 2546: 2545: 2541: 2532: 2530: 2521: 2520: 2516: 2478: 2477: 2473: 2427: 2426: 2422: 2376: 2375: 2371: 2366: 2362: 2326: 2325: 2321: 2285: 2284: 2280: 2271: 2267: 2262: 2258: 2204: 2203: 2199: 2177: 2176: 2172: 2128: 2127: 2123: 2082:(4): e0174518. 2069: 2068: 2064: 2014: 2013: 2009: 1972:Nat Rev Microbi 1965: 1964: 1960: 1906: 1905: 1898: 1876: 1875: 1868: 1812: 1811: 1807: 1798: 1796: 1788: 1787: 1783: 1744:"Acne vulgaris" 1741: 1740: 1736: 1708: 1707: 1700: 1691: 1689: 1684: 1683: 1679: 1649: 1648: 1644: 1606: 1605: 1601: 1555: 1554: 1550: 1520: 1519: 1515: 1505: 1503: 1466: 1465: 1461: 1451: 1449: 1418: 1417: 1413: 1403: 1401: 1400:. April 2, 2017 1392: 1391: 1387: 1343: 1342: 1338: 1324: 1323: 1319: 1290:(12): 1149–56. 1281: 1280: 1276: 1239:(5684): 671–3. 1230: 1229: 1225: 1181: 1180: 1176: 1145:(10): 2969–70. 1132: 1131: 1127: 1115: 1114: 1107: 1097: 1095: 1087: 1086: 1082: 1036: 1035: 1024: 1014: 1012: 983: 978: 977: 966: 956: 954: 941: 940: 931: 926: 884: 845: 837:4000–8000 μg/mL 763: 695: 664: 618:infections and 601: 573: 565:herniated discs 558: 556:Disk herniation 542:endophthalmitis 535: 483: 457: 385: 380: 266:endophthalmitis 158: 155: 149: 136: 54: 28: 23: 22: 15: 12: 11: 5: 4631: 4629: 4621: 4620: 4615: 4610: 4600: 4599: 4593: 4592: 4590: 4589: 4576: 4566: 4553: 4540: 4527: 4514: 4501: 4488: 4475: 4462: 4447: 4431: 4429: 4423: 4422: 4417: 4408: 4407: 4405: 4404: 4396: 4394: 4388: 4387: 4384: 4383: 4381: 4380: 4379: 4378: 4366: 4365: 4364: 4352: 4351: 4350: 4337: 4335: 4329: 4328: 4326: 4325: 4318: 4317: 4316: 4295: 4293: 4287: 4286: 4283: 4282: 4279: 4278: 4276: 4275: 4268: 4261: 4253: 4251: 4240: 4239: 4237: 4236: 4233:M. haemophilum 4229: 4228: 4227: 4215: 4214: 4213: 4183: 4181: 4174: 4173: 4171: 4170: 4162: 4160: 4153: 4152: 4150: 4149: 4148: 4147: 4135: 4127: 4125: 4115: 4113:Nontuberculous 4109: 4108: 4106: 4105: 4100: 4095: 4090: 4085: 4080: 4070: 4068: 4060: 4059: 4057: 4056: 4051: 4046: 4041: 4036: 4031: 4026: 4021: 4020: 4019: 4009: 4004: 4003: 4002: 3997: 3992: 3987: 3982: 3980:Lupus vulgaris 3977: 3972: 3960: 3959: 3958: 3948: 3947: 3946: 3941: 3931: 3926: 3924:Ghon's complex 3912: 3910: 3894: 3885: 3879: 3878: 3875: 3874: 3872: 3871: 3863: 3861: 3855: 3854: 3852: 3851: 3844: 3843: 3842: 3830: 3829: 3828: 3814: 3813: 3812: 3807: 3794: 3792: 3783: 3781:Actinomycineae 3777: 3776: 3773:Actinomycetota 3767: 3765: 3764: 3757: 3750: 3742: 3736: 3735: 3722: 3716: 3706: 3692: 3691:External links 3689: 3686: 3685: 3664:(5): 1059–65. 3644: 3593: 3550: 3507: 3444: 3417:(7): 786–794. 3401: 3366: 3331: 3290: 3247: 3216: 3189: 3148: 3105: 3062: 3011: 2997: 2971: 2945: 2918: 2874: 2823: 2761: 2734:(8): 1233–47. 2718: 2697: 2648: 2599: 2564: 2539: 2514: 2471: 2420: 2369: 2360: 2319: 2305:10.1086/588477 2298:(12): 1884–6. 2278: 2265: 2256: 2197: 2170: 2141:(4): 697–707. 2121: 2062: 2027:(5): 330–333. 2007: 1978:(8): 555–567. 1958: 1921:Microorganisms 1896: 1885:(3): 197–203. 1866: 1805: 1781: 1734: 1698: 1677: 1642: 1599: 1548: 1513: 1459: 1411: 1385: 1336: 1317: 1274: 1223: 1174: 1125: 1105: 1080: 1022: 964: 928: 927: 925: 922: 883: 882:Other habitats 880: 844: 841: 820:Salicylic acid 771:essential oils 762: 759: 749:salicylic acid 694: 691: 663: 660: 600: 597: 572: 569: 557: 554: 550:corneal ulcers 534: 531: 523:S. epidermidis 515:Staphylococcus 482: 477:Staphylococcus 474: 384: 381: 379: 376: 336:propionic acid 328:Bacillus acnes 284:for degrading 223: 222: 221: 220: 212: 210:Gilchrist 1900 206:Bacillus acnes 199: 198: 192: 191: 190: 189: 182: 175: 165: 164: 160: 159: 156: 145: 144: 138: 137: 130: 128: 124: 123: 116: 112: 111: 106: 102: 101: 96: 92: 91: 86: 82: 81: 79:Actinomycetota 76: 72: 71: 66: 62: 61: 48: 47: 39: 38: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 4630: 4619: 4616: 4614: 4611: 4609: 4606: 4605: 4603: 4586: 4581: 4577: 4573: 4567: 4563: 4558: 4554: 4550: 4545: 4541: 4537: 4532: 4528: 4524: 4519: 4515: 4511: 4506: 4502: 4498: 4493: 4489: 4485: 4480: 4476: 4472: 4467: 4463: 4458: 4452: 4448: 4443: 4437: 4433: 4432: 4430: 4428: 4424: 4420: 4415: 4403: 4402: 4398: 4397: 4395: 4393: 4389: 4377: 4374: 4373: 4372: 4371: 4367: 4363: 4360: 4359: 4358: 4357: 4353: 4349: 4346: 4345: 4344: 4343: 4339: 4338: 4336: 4334: 4330: 4324: 4323: 4319: 4315: 4312: 4311: 4310: 4309: 4305: 4301: 4297: 4296: 4294: 4292: 4288: 4274: 4273: 4269: 4267: 4266: 4262: 4260: 4259: 4255: 4254: 4252: 4249: 4245: 4241: 4235: 4234: 4230: 4226: 4223: 4222: 4221: 4220: 4216: 4212: 4211:MAI infection 4209: 4208: 4207: 4203: 4202: 4197: 4196: 4191: 4189: 4185: 4184: 4182: 4179: 4175: 4169: 4168: 4164: 4163: 4161: 4158: 4154: 4146: 4143: 4142: 4141: 4140: 4136: 4134: 4133: 4129: 4128: 4126: 4123: 4119: 4116: 4114: 4110: 4104: 4101: 4099: 4096: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4075: 4072: 4071: 4069: 4067: 4066: 4061: 4055: 4052: 4050: 4047: 4045: 4042: 4040: 4037: 4035: 4032: 4030: 4027: 4025: 4022: 4018: 4015: 4014: 4013: 4010: 4008: 4005: 4001: 3998: 3996: 3993: 3991: 3988: 3986: 3983: 3981: 3978: 3976: 3973: 3971: 3970:Scrofuloderma 3968: 3967: 3966: 3965: 3961: 3957: 3954: 3953: 3952: 3949: 3945: 3942: 3940: 3937: 3936: 3935: 3932: 3930: 3927: 3925: 3921: 3917: 3914: 3913: 3911: 3909: 3908: 3903: 3898: 3895: 3893: 3889: 3886: 3884: 3880: 3870: 3869: 3865: 3864: 3862: 3860: 3856: 3850: 3849: 3845: 3841: 3838: 3837: 3836: 3835: 3831: 3827: 3824: 3823: 3821: 3820: 3815: 3811: 3808: 3806: 3805:Actinomycosis 3803: 3802: 3801: 3800: 3796: 3795: 3793: 3791: 3787: 3784: 3782: 3778: 3774: 3770: 3763: 3758: 3756: 3751: 3749: 3744: 3743: 3740: 3734: 3732: 3728: 3723: 3720: 3717: 3714: 3710: 3707: 3704: 3699: 3695: 3694: 3690: 3681: 3677: 3672: 3667: 3663: 3659: 3655: 3648: 3645: 3640: 3636: 3631: 3626: 3621: 3616: 3612: 3608: 3604: 3597: 3594: 3589: 3585: 3581: 3577: 3573: 3569: 3565: 3561: 3554: 3551: 3546: 3542: 3538: 3534: 3530: 3526: 3522: 3518: 3511: 3508: 3503: 3499: 3494: 3489: 3484: 3479: 3475: 3471: 3467: 3463: 3459: 3457: 3448: 3445: 3440: 3436: 3432: 3428: 3424: 3420: 3416: 3412: 3405: 3402: 3397: 3393: 3389: 3385: 3381: 3377: 3370: 3367: 3362: 3358: 3354: 3350: 3346: 3342: 3335: 3332: 3327: 3323: 3318: 3313: 3310:(2): 258–65. 3309: 3305: 3301: 3294: 3291: 3286: 3282: 3278: 3274: 3270: 3266: 3263:(9): 1012–9. 3262: 3258: 3251: 3248: 3243: 3239: 3235: 3231: 3227: 3220: 3217: 3212: 3208: 3204: 3200: 3193: 3190: 3185: 3181: 3176: 3171: 3167: 3163: 3159: 3152: 3149: 3144: 3140: 3136: 3132: 3128: 3124: 3120: 3116: 3109: 3106: 3101: 3097: 3093: 3089: 3085: 3081: 3077: 3073: 3072:Planta Medica 3066: 3063: 3058: 3054: 3049: 3044: 3039: 3034: 3030: 3026: 3022: 3015: 3012: 3000: 2994: 2990: 2985: 2984: 2975: 2972: 2959: 2955: 2949: 2946: 2941: 2937: 2934:(6): 417–21. 2933: 2929: 2922: 2919: 2914: 2910: 2906: 2902: 2898: 2894: 2890: 2886: 2878: 2875: 2870: 2866: 2862: 2858: 2854: 2850: 2846: 2842: 2839:(3): 467–78. 2838: 2834: 2827: 2824: 2819: 2815: 2811: 2807: 2803: 2799: 2795: 2791: 2786: 2781: 2778:(2): 339–46. 2777: 2773: 2765: 2762: 2757: 2753: 2749: 2745: 2741: 2737: 2733: 2729: 2722: 2719: 2707: 2701: 2698: 2693: 2689: 2684: 2679: 2675: 2671: 2667: 2663: 2659: 2652: 2649: 2644: 2640: 2635: 2630: 2626: 2622: 2619:(3): 387–94. 2618: 2614: 2610: 2603: 2600: 2595: 2591: 2587: 2583: 2580:(4): 651–63. 2579: 2575: 2568: 2565: 2554:on 2017-10-11 2553: 2549: 2543: 2540: 2529:on 2012-06-20 2528: 2524: 2518: 2515: 2510: 2506: 2502: 2498: 2494: 2490: 2486: 2482: 2475: 2472: 2467: 2463: 2458: 2453: 2448: 2443: 2439: 2435: 2431: 2424: 2421: 2416: 2412: 2407: 2402: 2397: 2392: 2388: 2384: 2380: 2373: 2370: 2364: 2361: 2356: 2352: 2347: 2342: 2339:(4): 387–94. 2338: 2334: 2330: 2323: 2320: 2315: 2311: 2306: 2301: 2297: 2293: 2289: 2282: 2279: 2275: 2269: 2266: 2260: 2257: 2252: 2248: 2243: 2238: 2233: 2228: 2224: 2220: 2217:(8): e12277. 2216: 2212: 2208: 2201: 2198: 2193: 2189: 2186:(2): 115–30. 2185: 2181: 2174: 2171: 2166: 2162: 2157: 2152: 2148: 2144: 2140: 2136: 2132: 2125: 2122: 2117: 2113: 2108: 2103: 2098: 2093: 2089: 2085: 2081: 2077: 2073: 2066: 2063: 2058: 2054: 2050: 2046: 2042: 2038: 2034: 2030: 2026: 2022: 2018: 2011: 2008: 2003: 1999: 1994: 1989: 1985: 1981: 1977: 1973: 1969: 1962: 1959: 1954: 1950: 1945: 1940: 1935: 1930: 1926: 1922: 1918: 1916: 1912: 1903: 1901: 1897: 1892: 1888: 1884: 1880: 1873: 1871: 1867: 1862: 1858: 1854: 1850: 1846: 1842: 1838: 1834: 1829: 1824: 1821:(3): 467–78. 1820: 1816: 1809: 1806: 1795: 1791: 1785: 1782: 1777: 1773: 1769: 1765: 1761: 1757: 1753: 1749: 1745: 1738: 1735: 1729: 1724: 1720: 1716: 1715:F1000Research 1712: 1705: 1703: 1699: 1687: 1681: 1678: 1673: 1669: 1665: 1661: 1657: 1653: 1646: 1643: 1638: 1634: 1630: 1626: 1622: 1618: 1614: 1610: 1603: 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202: 200: 197: 193: 188: 187: 183: 181: 180: 176: 174: 173: 169: 168: 166: 161: 154: 152: 146: 143: 142:Binomial name 139: 135: 134: 133:C. acnes 129: 126: 125: 122: 121: 120:Cutibacterium 117: 114: 113: 110: 107: 104: 103: 100: 97: 94: 93: 90: 89:Actinomycetia 87: 84: 83: 80: 77: 74: 73: 70: 67: 64: 63: 58: 53: 49: 45: 40: 37: 33: 30: 19: 4426: 4399: 4368: 4354: 4340: 4320: 4298: 4291:Nocardiaceae 4272:M. abscessus 4270: 4263: 4258:M. fortuitum 4256: 4231: 4225:Buruli ulcer 4217: 4199: 4193: 4187: 4165: 4137: 4130: 4063: 3962: 3933: 3929:Pott disease 3916:Tuberculosis 3900: 3866: 3846: 3832: 3817: 3797: 3730: 3726: 3661: 3657: 3647: 3610: 3606: 3596: 3566:(2): 200–1. 3563: 3559: 3553: 3523:(5): 973–8. 3520: 3516: 3510: 3468:(1): 14658. 3465: 3461: 3455: 3447: 3414: 3410: 3404: 3382:(9): 895–9. 3379: 3375: 3369: 3347:(1): 28–35. 3344: 3340: 3334: 3307: 3303: 3293: 3260: 3256: 3250: 3233: 3229: 3219: 3205:(1): 13–39. 3202: 3198: 3192: 3165: 3161: 3151: 3121:(4): 242–5. 3118: 3114: 3108: 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Retrieved 2982: 2974: 2962:. Retrieved 2957: 2948: 2931: 2927: 2921: 2891:(5): 840–8. 2888: 2884: 2877: 2836: 2832: 2826: 2775: 2771: 2764: 2731: 2727: 2721: 2710:. Retrieved 2700: 2668:(1): 171–3. 2665: 2661: 2651: 2616: 2612: 2602: 2577: 2573: 2567: 2556:. Retrieved 2552:the original 2542: 2531:. Retrieved 2527:the original 2517: 2484: 2480: 2474: 2437: 2433: 2423: 2386: 2382: 2372: 2363: 2336: 2332: 2322: 2295: 2291: 2281: 2268: 2259: 2214: 2210: 2200: 2183: 2179: 2173: 2138: 2134: 2124: 2079: 2075: 2065: 2024: 2020: 2010: 1975: 1971: 1961: 1927:(11): 1752. 1924: 1920: 1914: 1910: 1882: 1878: 1818: 1814: 1808: 1797:. Retrieved 1793: 1784: 1754:(1): 15029. 1751: 1747: 1737: 1718: 1714: 1690:. Retrieved 1680: 1658:(5): 360–6. 1655: 1651: 1645: 1615:(3): 193–8. 1612: 1608: 1602: 1565: 1561: 1551: 1529:(5): 360–6. 1526: 1522: 1516: 1504:. Retrieved 1476: 1472: 1462: 1450:. Retrieved 1428: 1424: 1414: 1402:. Retrieved 1397: 1388: 1356:(1): 15–23. 1353: 1349: 1339: 1330: 1326: 1320: 1287: 1283: 1277: 1236: 1232: 1226: 1191: 1187: 1177: 1142: 1138: 1128: 1118: 1096:. Retrieved 1092: 1083: 1046: 1042: 1013:. Retrieved 991: 987: 955:. Retrieved 951:the original 946: 913: 907: 898: 886: 885: 871: 863: 847: 846: 832: 829: 816: 814: 809: 795: 790: 775:tea tree oil 766: 764: 757: 728: 726: 718:lincosamides 714:azithromycin 705: 701: 696: 686: 671:erythromycin 666: 665: 627: 620:endocarditis 603: 602: 587: 575: 574: 560: 559: 537: 536: 527: 522: 518: 514: 510: 504: 500: 494: 486: 484: 479: 476: 470:isotretinoin 460: 456: 434: 427:folliculitis 422: 417: 416: 411: 395: 387: 386: 371: 365: 359: 355: 351: 347: 339: 331: 327: 325: 298: 240:aerotolerant 234: 233: 228: 227: 226: 214: 205: 184: 177: 172:subsp. acnes 170: 150: 148: 132: 131: 119: 35: 29: 4505:iNaturalist 4451:Wikispecies 4314:Nocardiosis 4265:M. chelonae 4219:M. ulcerans 4167:M. gordonae 4132:M. kansasii 3236:(1): 74–9. 3168:(1): 86–8. 1609:Dermatology 1066:2434/620522 918:Frank Zappa 912:was dubbed 783:citrus oils 683:minocycline 679:doxycycline 675:clindamycin 636:sarcoidosis 584:sarcoidosis 571:Sarcoidosis 480:epidermidis 338:. In 2016, 309:fatty acids 262:blepharitis 163:Subspecies 4602:Categories 4362:Erythrasma 4348:Diphtheria 4139:M. marinum 4012:Tuberculid 3944:Rich focus 3939:Meningitis 3920:Ghon focus 3613:: 145–63. 2853:10454/3069 2802:10454/3311 2785:1510.02343 2712:2012-08-08 2558:2019-11-18 2533:2012-06-14 2440:: 804391. 1845:10454/3069 1799:2022-04-22 1692:2012-06-14 1333:: 409–430. 924:References 856:porphyrins 852:blacklight 761:Treatments 710:macrolides 658:cultures. 612:prostheses 544:following 493:, such as 305:skin flora 4065:M. leprae 3964:cutaneous 3439:108295123 3031:: 79–83. 3004:17 August 2964:17 August 2509:205850559 2041:1542-233X 1828:0706.4406 1768:2056-676X 1506:17 August 1452:17 August 1404:17 August 1098:17 August 1015:17 August 957:17 August 903:grapevine 895:grapevine 891:endophyte 825:mechanism 817:C. acnes. 779:clove oil 741:triclosan 727:However, 317:follicles 301:commensal 250:bacterium 243:anaerobic 127:Species: 4523:10032060 4442:Q2442109 4436:Wikidata 4188:M. avium 3907:M. bovis 3680:24554779 3639:24899818 3588:30935383 3580:18452529 3537:10809858 3502:31601845 3456:In vitro 3431:30972839 3361:13069766 3326:19942617 3285:12053077 3277:17133045 3242:18239420 3184:19153353 3100:37769650 3092:17893831 3057:22936850 2940:19181031 2905:12000382 2869:20838517 2861:12653738 2818:44614220 2810:11251569 2756:26957816 2748:21355786 2594:17276540 2501:29125405 2466:24308006 2415:28676754 2355:19260876 2314:18462110 2251:20808860 2211:PLOS ONE 2192:18326339 2165:23404353 2116:28369127 2076:PLOS ONE 2057:22829150 2049:27203796 2002:19609257 1953:33171837 1891:14620162 1861:20838517 1853:12653738 1776:27189872 1721:: 1953. 1672:15556719 1637:21459334 1629:16205063 1594:20799957 1543:15556719 1493:29544969 1447:29544912 1380:16561149 1312:42012357 1304:22114965 1269:26252335 1261:15286373 1218:25125638 1169:11583007 1075:29894579 1010:27488827 908:C. acnes 899:C. acnes 872:in vitro 864:C. acnes 810:C. acnes 791:C. acnes 767:C. acnes 729:C. acnes 706:C. acnes 702:C. acnes 687:C. acnes 640:sciatica 628:C. acnes 588:C. acnes 519:C. acnes 511:C. acnes 501:C. acnes 487:C. acnes 461:C. acnes 440:biofilms 435:C. acnes 423:C. acnes 412:C. acnes 396:C. acnes 372:C. acnes 348:P. acnes 340:P. acnes 290:proteins 196:Synonyms 105:Family: 75:Phylum: 69:Bacteria 65:Domain: 4497:3225701 4466:BacDive 4190:complex 4074:Leprosy 4029:Miliary 3630:4038525 3545:9237317 3493:6787063 3470:Bibcode 3396:8242490 3143:5687026 3135:7576514 3048:3426266 2913:5725343 2457:3838805 2406:5476743 2389:: 195. 2242:2924382 2219:Bibcode 2180:Kekkaku 2156:3631045 2107:5378350 2084:Bibcode 1993:2807625 1944:7695133 1585:3224659 1568:: 230. 1501:3916758 1241:Bibcode 1233:Science 1209:4132614 910:subtype 282:enzymes 115:Genus: 95:Order: 85:Class: 4585:360356 4569:NZOR: 4536:965070 4510:356609 4484:971823 3729:at Bac 3715:(MeSH) 3678:  3637:  3627:  3586:  3578:  3543:  3535:  3500:  3490:  3437:  3429:  3394:  3359:  3324:  3283:  3275:  3257:Cornea 3240:  3182:  3141:  3133:  3098:  3090:  3055:  3045:  2995:  2938:  2911:  2903:  2867:  2859:  2816:  2808:  2754:  2746:  2692:836012 2690:  2683:351938 2680:  2643:984781 2641:  2634:429758 2631:  2592:  2507:  2499:  2464:  2454:  2413:  2403:  2353:  2312:  2249:  2239:  2190:  2163:  2153:  2114:  2104:  2055:  2047:  2039:  2000:  1990:  1951:  1941:  1889:  1859:  1851:  1774:  1766:  1670:  1635:  1627:  1592:  1582:  1541:  1499:  1491:  1445:  1378:  1371:518134 1368:  1310:  1302:  1267:  1259:  1216:  1206:  1167:  1157:  1073:  1008:  914:Zappae 806:copper 804:, and 802:sulfur 798:silver 781:, and 681:, and 364:, and 274:genome 272:. Its 4518:IRMNG 4471:12636 3934:brain 3584:S2CID 3541:S2CID 3435:S2CID 3281:S2CID 3139:S2CID 3096:S2CID 2928:Cutis 2909:S2CID 2865:S2CID 2814:S2CID 2780:arXiv 2752:S2CID 2505:S2CID 2053:S2CID 1857:S2CID 1823:arXiv 1633:S2CID 1497:S2CID 1308:S2CID 1265:S2CID 1160:90767 984:(PDF) 833:acnes 787:honey 652:blood 632:SAPHO 616:shunt 400:sebum 392:pores 313:sebum 278:genes 4562:1747 4557:NCBI 4544:LPSN 4531:ITIS 4492:GBIF 3731:Dive 3676:PMID 3635:PMID 3576:PMID 3533:PMID 3498:PMID 3427:PMID 3392:PMID 3357:PMID 3322:PMID 3273:PMID 3238:PMID 3180:PMID 3131:PMID 3088:PMID 3053:PMID 3006:2018 2993:ISBN 2966:2018 2936:PMID 2901:PMID 2857:PMID 2806:PMID 2744:PMID 2688:PMID 2639:PMID 2590:PMID 2497:PMID 2462:PMID 2438:2013 2411:PMID 2351:PMID 2310:PMID 2247:PMID 2188:PMID 2161:PMID 2112:PMID 2045:PMID 2037:ISSN 1998:PMID 1949:PMID 1913:and 1887:PMID 1849:PMID 1772:PMID 1764:ISSN 1668:PMID 1625:PMID 1590:PMID 1539:PMID 1508:2018 1489:PMID 1454:2018 1443:PMID 1406:2018 1376:PMID 1300:PMID 1257:PMID 1214:PMID 1165:PMID 1100:2018 1093:LPSN 1071:PMID 1017:2018 1006:PMID 959:2018 751:and 654:and 638:and 521:and 429:and 288:and 286:skin 264:and 258:acne 254:skin 4479:EoL 4206:MAP 3666:doi 3625:PMC 3615:doi 3568:doi 3525:doi 3521:142 3488:PMC 3478:doi 3419:doi 3384:doi 3349:doi 3312:doi 3265:doi 3207:doi 3170:doi 3166:145 3123:doi 3080:doi 3043:PMC 3033:doi 2989:130 2893:doi 2889:146 2849:hdl 2841:doi 2837:148 2798:hdl 2790:doi 2776:144 2736:doi 2678:PMC 2670:doi 2629:PMC 2621:doi 2582:doi 2489:doi 2452:PMC 2442:doi 2401:PMC 2391:doi 2341:doi 2300:doi 2237:PMC 2227:doi 2151:PMC 2143:doi 2102:PMC 2092:doi 2029:doi 1988:PMC 1980:doi 1939:PMC 1929:doi 1841:hdl 1833:doi 1819:148 1756:doi 1723:doi 1660:doi 1617:doi 1613:211 1580:PMC 1570:doi 1531:doi 1481:doi 1433:doi 1366:PMC 1358:doi 1292:doi 1249:doi 1237:305 1204:PMC 1196:doi 1155:PMC 1147:doi 1061:hdl 1051:doi 996:doi 716:), 646:in 311:in 296:). 4604:: 4582:: 4559:: 4546:: 4533:: 4520:: 4507:: 4494:: 4481:: 4468:: 4453:: 4438:: 4248:RG 4244:R4 4178:R3 4157:R2 4122:R1 4076:: 3918:: 3822:" 3771:: 3674:. 3662:31 3660:. 3656:. 3633:. 3623:. 3609:. 3605:. 3582:. 3574:. 3564:23 3562:. 3539:. 3531:. 3519:. 3496:. 3486:. 3476:. 3464:. 3460:. 3433:. 3425:. 3415:28 3413:. 3390:. 3380:39 3378:. 3355:. 3345:93 3343:. 3320:. 3308:65 3306:. 3302:. 3279:. 3271:. 3261:25 3259:. 3234:18 3232:. 3228:. 3203:27 3201:. 3178:. 3164:. 3160:. 3137:. 3129:. 3119:21 3117:. 3094:. 3086:. 3076:73 3074:. 3051:. 3041:. 3027:. 3023:. 2991:. 2956:. 2932:82 2930:. 2907:. 2899:. 2887:. 2863:. 2855:. 2847:. 2835:. 2812:. 2804:. 2796:. 2788:. 2774:. 2750:. 2742:. 2732:12 2730:. 2686:. 2676:. 2666:11 2664:. 2660:. 2637:. 2627:. 2617:10 2615:. 2611:. 2588:. 2578:56 2576:. 2503:. 2495:. 2485:15 2483:. 2460:. 2450:. 2436:. 2432:. 2409:. 2399:. 2385:. 2381:. 2349:. 2337:15 2335:. 2331:. 2308:. 2296:46 2294:. 2290:. 2245:. 2235:. 2225:. 2213:. 2209:. 2184:83 2182:. 2159:. 2149:. 2139:22 2137:. 2133:. 2110:. 2100:. 2090:. 2080:12 2078:. 2074:. 2051:. 2043:. 2035:. 2025:43 2023:. 2019:. 1996:. 1986:. 1974:. 1970:. 1947:. 1937:. 1923:. 1919:. 1899:^ 1883:20 1881:. 1869:^ 1855:. 1847:. 1839:. 1831:. 1817:. 1792:. 1770:. 1762:. 1750:. 1746:. 1717:. 1713:. 1701:^ 1666:. 1656:22 1654:. 1631:. 1623:. 1611:. 1588:. 1578:. 1566:10 1564:. 1560:. 1537:. 1527:22 1525:. 1495:. 1487:. 1477:33 1475:. 1471:. 1441:. 1429:24 1427:. 1423:. 1396:. 1374:. 1364:. 1354:52 1352:. 1348:. 1329:. 1306:. 1298:. 1286:. 1263:. 1255:. 1247:. 1235:. 1212:. 1202:. 1190:. 1186:. 1163:. 1153:. 1143:45 1141:. 1137:. 1108:^ 1091:. 1069:. 1059:. 1047:32 1045:. 1041:. 1025:^ 1004:. 992:66 990:. 986:. 967:^ 945:. 932:^ 862:. 839:. 830:C. 812:. 800:, 793:. 777:, 755:. 747:, 743:, 739:, 677:, 673:, 552:. 358:, 323:. 245:, 208:" 4306:/ 4302:/ 4250:: 4246:/ 4204:/ 4198:/ 4192:/ 4180:: 4159:: 4124:: 3922:/ 3904:/ 3816:" 3761:e 3754:t 3747:v 3682:. 3668:: 3641:. 3617:: 3611:7 3590:. 3570:: 3547:. 3527:: 3504:. 3480:: 3472:: 3466:9 3454:" 3441:. 3421:: 3398:. 3386:: 3363:. 3351:: 3328:. 3314:: 3287:. 3267:: 3244:. 3213:. 3209:: 3186:. 3172:: 3145:. 3125:: 3102:. 3082:: 3059:. 3035:: 3029:5 3008:. 2968:. 2942:. 2915:. 2895:: 2871:. 2851:: 2843:: 2820:. 2800:: 2792:: 2782:: 2758:. 2738:: 2715:. 2694:. 2672:: 2645:. 2623:: 2596:. 2584:: 2561:. 2536:. 2511:. 2491:: 2468:. 2444:: 2417:. 2393:: 2387:9 2357:. 2343:: 2316:. 2302:: 2253:. 2229:: 2221:: 2215:5 2194:. 2167:. 2145:: 2118:. 2094:: 2086:: 2059:. 2031:: 2004:. 1982:: 1976:7 1955:. 1931:: 1925:8 1909:" 1893:. 1863:. 1843:: 1835:: 1825:: 1802:. 1778:. 1758:: 1752:1 1731:. 1725:: 1719:7 1695:. 1674:. 1662:: 1639:. 1619:: 1596:. 1572:: 1545:. 1533:: 1510:. 1483:: 1456:. 1435:: 1408:. 1382:. 1360:: 1331:9 1314:. 1294:: 1288:9 1271:. 1251:: 1243:: 1220:. 1198:: 1192:2 1171:. 1149:: 1102:. 1077:. 1063:: 1053:: 1019:. 998:: 961:. 406:( 232:( 204:" 20:)

Index

Propionibacterium acnes

Scientific classification
Edit this classification
Bacteria
Actinomycetota
Actinomycetia
Propionibacteriales
Propionibacteriaceae
Cutibacterium
Binomial name
subsp. acnes
subsp. defendens
subsp. elongatum
Synonyms
aerotolerant
anaerobic
gram-positive
bacterium
skin
acne
blepharitis
endophthalmitis
intraocular surgery
genome
genes
enzymes
skin
proteins
immune system

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