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Quantitative pharmacology

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to late-stage development. QP encourages more transparent and objective study designs, as well as more data-driven risk-taking to optimize timelines, analyses, and decision-making, resulting in greater efficiency in the drug development process.
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Barrett, JS; Shi, J; Xie, HT; Huang, XH; Fossler, MJ; Sun, RY (Jul 2008). "Globalization of quantitative pharmacology: first international symposium of quantitative pharmacology in drug development and regulation".
215:, and individual variability into improved patient outcomes by leveraging improved teamwork and collaboration to enable quantitative decision-making processes from 546:
Zhang, L; Sinha, V; Forgue, ST; Callies, S; Ni, L; Peck, R; Allerheiligen, SR (Jun 2006). "Model-based drug development: the road to quantitative pharmacology".
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Putnam, WS; Li, J; Haggstrom, J; Ng, C; Kadkhodayan-Fischer, S; Cheu, M; Deniz, Y; Lowman, H; Fielder, P; Visich, J; Joshi, A; Jumbe, NS (Jun 2008).
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Atkinson, AJ Jr; Lalonde, RL (Jul 2007). "Introduction of quantitative methods in pharmacology and clinical pharmacology: a historical overview".
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Holford, N; Karlsson, MO (Jul 2007). "Time for quantitative clinical pharmacology: a proposal for a pharmacometrics curriculum".
41: 132: 126: 199:(QSP), is an organized approach integrating individuals from different disciplines in a combined effort to develop 143: 462:"Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-IgE monoclonal antibody" 200: 571: 448: 405: 368: 287: 563: 534: 491: 440: 397: 360: 330: 279: 237: 555: 524: 516: 481: 473: 430: 389: 352: 320: 312: 271: 204: 301:"The role of quantitative pharmacology in an academic translational research environment" 529: 505:"Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development" 504: 486: 461: 325: 300: 216: 586: 575: 452: 409: 372: 291: 212: 559: 520: 477: 316: 435: 418: 356: 393: 275: 567: 538: 495: 444: 401: 364: 334: 283: 208: 419:"Quantitative clinical pharmacology: Making paradigm shifts a reality" 72:
provides insufficient context for those unfamiliar with the subject
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in order to solve specific, complex, and multivariate problems in
111: 56: 15: 77: 8: 207:. QP translates the relationship(s) between 50:Learn how and when to remove these messages 528: 503:Zhang, L; Pfister, M; Meibohm, B (2008). 485: 434: 324: 180:Learn how and when to remove this message 162:Learn how and when to remove this message 100:Learn how and when to remove this message 125:This article includes a list of general 229: 82:providing more context for the reader 7: 593:Mathematical and theoretical biology 238:"Quantitative Systems Pharmacology" 131:it lacks sufficient corresponding 14: 197:Quantitative Systems Pharmacology 31:This article has multiple issues. 244:. Cambridge Healthtech Institute 116: 61: 20: 39:or discuss these issues on the 1: 548:J Pharmacokinet Pharmacodyn 609: 560:10.1007/s10928-006-9010-8 521:10.1208/s12248-008-9062-3 478:10.1208/s12248-008-9045-4 317:10.1208/s12248-007-9002-7 193:Quantitative Pharmacology 436:10.1177/0091270006292978 357:10.1177/0091270008319331 417:Krishna, R (Sep 2006). 394:10.1038/sj.clpt.6100231 276:10.1038/sj.clpt.6100248 146:more precise citations. 299:Barrett, JS (2008). 382:Clin Pharmacol Ther 264:Clin Pharmacol Ther 242:Discovery on Target 201:quantitative models 78:improve the article 190: 189: 182: 172: 171: 164: 110: 109: 102: 54: 600: 579: 542: 532: 499: 489: 456: 438: 423:J Clin Pharmacol 413: 376: 345:J Clin Pharmacol 338: 328: 295: 254: 253: 251: 249: 234: 205:drug development 185: 178: 167: 160: 156: 153: 147: 142:this article by 133:inline citations 120: 119: 112: 105: 98: 94: 91: 85: 65: 64: 57: 46: 24: 23: 16: 608: 607: 603: 602: 601: 599: 598: 597: 583: 582: 545: 502: 459: 416: 379: 341: 298: 261: 258: 257: 247: 245: 236: 235: 231: 226: 217:early discovery 186: 175: 174: 173: 168: 157: 151: 148: 138:Please help to 137: 121: 117: 106: 95: 89: 86: 75: 66: 62: 25: 21: 12: 11: 5: 606: 604: 596: 595: 585: 584: 581: 580: 543: 500: 457: 414: 377: 339: 296: 256: 255: 228: 227: 225: 222: 188: 187: 170: 169: 124: 122: 115: 108: 107: 69: 67: 60: 55: 29: 28: 26: 19: 13: 10: 9: 6: 4: 3: 2: 605: 594: 591: 590: 588: 577: 573: 569: 565: 561: 557: 554:(3): 369–93. 553: 549: 544: 540: 536: 531: 526: 522: 518: 514: 510: 506: 501: 497: 493: 488: 483: 479: 475: 472:(2): 425–30. 471: 467: 463: 458: 454: 450: 446: 442: 437: 432: 428: 424: 420: 415: 411: 407: 403: 399: 395: 391: 387: 383: 378: 374: 370: 366: 362: 358: 354: 351:(7): 787–92. 350: 346: 340: 336: 332: 327: 322: 318: 314: 310: 306: 302: 297: 293: 289: 285: 281: 277: 273: 269: 265: 260: 259: 243: 239: 233: 230: 223: 221: 218: 214: 210: 206: 202: 198: 194: 184: 181: 166: 163: 155: 145: 141: 135: 134: 128: 123: 114: 113: 104: 101: 93: 83: 79: 73: 70:This article 68: 59: 58: 53: 51: 44: 43: 38: 37: 32: 27: 18: 17: 551: 547: 515:(4): 552–9. 512: 508: 469: 465: 429:(9): 966–7. 426: 422: 388:(1): 103–5. 385: 381: 348: 344: 308: 304: 267: 263: 246:. Retrieved 241: 232: 196: 192: 191: 176: 158: 149: 130: 96: 87: 76:Please help 71: 47: 40: 34: 33:Please help 30: 311:(1): 9–14. 248:12 November 213:drug action 144:introducing 270:(1): 3–6. 224:References 152:April 2018 127:references 36:improve it 195:(QP), or 90:June 2020 42:talk page 587:Category 576:25246940 568:16770528 539:19003542 496:18686041 453:31443478 445:16920890 410:41815609 402:17495873 373:21049234 365:18490494 335:18446501 292:32337361 284:17571065 530:2628212 487:2751395 326:2751447 209:disease 140:improve 574:  566:  537:  527:  509:AAPS J 494:  484:  466:AAPS J 451:  443:  408:  400:  371:  363:  333:  323:  305:AAPS J 290:  282:  129:, but 572:S2CID 449:S2CID 406:S2CID 369:S2CID 288:S2CID 564:PMID 535:PMID 492:PMID 441:PMID 398:PMID 361:PMID 331:PMID 280:PMID 250:2015 556:doi 525:PMC 517:doi 482:PMC 474:doi 431:doi 390:doi 353:doi 321:PMC 313:doi 272:doi 80:by 589:: 570:. 562:. 552:33 550:. 533:. 523:. 513:10 511:. 507:. 490:. 480:. 470:10 468:. 464:. 447:. 439:. 427:46 425:. 421:. 404:. 396:. 386:82 384:. 367:. 359:. 349:48 347:. 329:. 319:. 309:10 307:. 303:. 286:. 278:. 268:82 266:. 240:. 211:, 45:. 578:. 558:: 541:. 519:: 498:. 476:: 455:. 433:: 412:. 392:: 375:. 355:: 337:. 315:: 294:. 274:: 252:. 183:) 177:( 165:) 159:( 154:) 150:( 136:. 103:) 97:( 92:) 88:( 84:. 74:. 52:) 48:(

Index

improve it
talk page
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improve the article
providing more context for the reader
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references
inline citations
improve
introducing
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quantitative models
drug development
disease
drug action
early discovery
"Quantitative Systems Pharmacology"
doi
10.1038/sj.clpt.6100248
PMID
17571065
S2CID
32337361
"The role of quantitative pharmacology in an academic translational research environment"
doi
10.1208/s12248-007-9002-7
PMC
2751447
PMID

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