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RECOVERY Trial

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When people who have been hospitalised with COVID-19 are enrolled in the trial, they are automatically randomized to receive trial treatments. If any treatment is contra-indicated (or positively indicated) for that patient, or is not available, then that treatment is not included in the randomization
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In December 2020, the chief investigators announced that they had found no benefit from azithromycin in patients hospitalised with COVID-19. 2582 patients had received azithromycin, and 5182 were randomised to usual care alone. 28-day mortality in both cohorts was 19%. These preliminary results were
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The very fast setting up of the trial was crucial for the fast-developing COVID-19 pandemic. Martin Landray, one of the trial's creators, said in March 2021 "I think it has set a new standard for what can be delivered and not just for pandemics. It would be a travesty if we went back to a situation
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In January 2021, the chief investigators announced the closure of the convalescent plasma arm of the trial. Among 1873 reported deaths from 10,405 patients, the trial reported "no significant difference in the primary endpoint of 28-day mortality (18% convalescent plasma vs. 18% usual care alone;
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emphasized that dexamethasone should only be used for patients with severe or critical disease, under close clinical supervision, stating that "There is no evidence this drug works for patients with mild disease or as a preventative measure, and it could cause
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The trial began in March 2020. As of March 2021 the trial had enrolled more than 40,000 COVID-19 participants admitted to hospitals in the UK; the estimated primary completion date was December 2021, and the estimated study completion date was December 2031.
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COVID-19 Treatment Guidelines Panel recommended dexamethasone in patients with COVID-19 who are on mechanical ventilation or those who require supplemental oxygen, and recommended against dexamethasone for those not requiring supplemental oxygen.
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In June 2020, chief investigators of the trial reported there was no clinical benefit from use of lopinavir-ritonavir in 1,596 people hospitalized with severe COVID-19 infection over 28 days of treatment. These results were published in
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Horby PW, Roddick A, Spata E, Staplin N, Emberson JR, Pessoa-Amorim G, et al. (14 December 2020). "Azithromycin in Hospitalised Patients with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial".
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A pre-print study, which was awarded Health Data Research UK Open Access Publication of the Month for August 2020, found that the discovery would save approximately 650,000 lives globally over the course of six months.
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process. The main randomization stage has three parts, so that patients might be allocated none, one, two or three of the trial treatments. If their disease progresses, there may also be a second randomization.
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Tocilizumab significantly reduces the risk of death when given to hospitalised patients with severe COVID-19. 2022 patients allocated to Tocilizumab were compared to 2094 who received standard hospital care.
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596 (29%) of the patients in the tocilizumab group died within 28 days compared with 694 (33%) patients in the usual care group (rate ratio 0·86; 0·77 to 0·96]; p=0·007), an absolute difference of 4%.
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The trial protocol was developed in March 2020. The design minimizes the administrative load on hospital staff, who at the time were facing the prospect of overwhelming numbers of COVID-19 admissions.
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This result supports the earlier findings of the Remap-Cap trial on the effectiveness of Tocilizumab for patients in intensive care, and extends those findings to a wider group of patients.
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The preprint authors themselves warned that "the results are consistent with possible harm" in patients who did not require oxygen at the time of enrolment. The trial observed a 22%
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A study published in January 2024 by the trial's chief investigators found that dimethyl fumarate did not significantly improve clinical outcomes in hospitalized COVID-19 patients.
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Aguas R, Mahdi A, Shretta R, Horby P, Landray M, White LJ (30 July 2020). "The potential health and economic impact of dexamethasone treatment for patients with COVID-19".
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The primary objective of the trial is to "provide reliable estimates of the effect of study treatments on all-cause mortality at 28 days after first randomization".
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The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JA, Murthy S, Diaz JV, Slutsky AS, Villar J, et al. (2 September 2020).
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in the United Kingdom exceptionally recommended an immediate change of UK-wide clinical practice, in advance of publication of any final paper.
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Six days before the pre-print, these results had been announced in a news release. A UK Therapeutic Alert was issued the same day, and all the
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Around a third of patients in the trial were still in hospital at the end of the 28-day trial period, so their final outcomes were not known.
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The following treatments have previously been included in the trial and were closed to new entrants after being shown to be ineffective.:
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Other countries granted specific approval for the drug as part of standard medical care, among them Japan, Taiwan and South Africa.
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RECOVERY Collaborative Group (2020). "Effect of Dexamethasone in Hospitalized Patients with COVID-19 – Preliminary Report".
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As of 25 June 2021, the following treatments are allocated at random to hospitalized people with severe COVID-19 infection:
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Mortality over 28 days for 1535 COVID-19 patients not receiving oxygen at time of randomisation: 501 patients who received
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The results of this initial finding were replicated in a systematic review published in September 2020 by the WHO's
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in mortality in these patients (rate ratio 1.22 ; p=0.14), though this observation may still be due to chance.
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Health Protection (Coronavirus, Restrictions) (Entry to Venues and Events) (England) Regulations 2021
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Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
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The following treatments have previously been included in the trial and obtained positive results:
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who serve as Co-Chief Investigators of the trial. By July 2020, the trial was in progress at 176
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Horby PW, Peto L, Staplin N, Campbell M, Pessoa-Amorim G, Mafham M, et al. (January 2024).
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Coronavirus, Restrictions (All Tiers and Self-Isolation) (England) (Amendment) Regulations 2021
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Horby PW, Mafham M, Bell JL, Linsell L, Staplin N, Emberson J, et al. (5 October 2020).
2282:" Receiving tocilizumab also increased the chance of discharge from hospital within 28 days. 5100: 4873: 4842: 4837: 4741: 4561: 3622: 3614: 3545: 3535: 3527: 3486: 3476: 3382: 3366: 3325: 3315: 3307: 3244: 3236: 3181: 3173: 2942: 2845: 2835: 2423: 2302: 1836: 1002: 968: 96: 2651:"No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19" 5254: 5230: 5204: 5180: 5001: 4965: 4940: 4585: 4239: 4136: 2679:"RECOVERY trial finds no benefit from azithromycin in patients hospitalised with COVID-19" 2181:, noted that there were "limitations and causes of concern" in the dexamethasone results. 1742: 4458:
Health Protection (Coronavirus, Restrictions) (Self-Isolation) (England) Regulations 2020
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The trial is run by the Nuffield Departments of Population Health and of Medicine at the
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risk ratio 1.04 ; p=0.34)". The article with full results was published on 14 May 2021.
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Health Protection (Coronavirus, Wearing of Face Coverings) (England) Regulations 2021
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Coronavirus, Restrictions (Local Authority Enforcement...) (England) Regulations 2020
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Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. (July 2020).
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In June 2020, preliminary results were published in a preprint showing that low-dose
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Coronavirus, International Travel and Operator Liability (England) Regulations 2021
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In June 2020, the trial determined that there was no clinical benefit from use of
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Health Protection (Coronavirus, Restrictions) (England) (No. 3) Regulations 2020
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Health Protection (Coronavirus, Restrictions) (England) (No. 4) Regulations 2020
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treatment reduced the death rate by one third in hospitalized people needing
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Health Protection (Coronavirus, Business Closure) (England) Regulations 2020
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Based on the preliminary, unpublished results of the RECOVERY trial, the US
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due to severe COVID-19 infection, and by one fifth in people treated with
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Health Protection (Coronavirus, Restrictions) (England) Regulations 2020
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hospitals in the UK, involving many thousands of health professionals.
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if you can. Unsourced or poorly sourced material may be challenged and
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Parliamentary Under-Secretary of State for COVID-19 Vaccine Deployment
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Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group
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Demand for dexamethasone surged after publication of the preprint.
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from people who have recovered from COVID-19 and which may contain
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Coronavirus, Restrictions (All Tiers) (England) Regulations 2020
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Chloroquine and hydroxychloroquine during the COVID-19 pandemic
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where it takes years sometimes to get a trial off the ground."
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for "Randomised Evaluation of COVID-19 Therapy (RECOVERY)" at
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Face Coverings in a Relevant Place (England) Regulations 2020
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Face Coverings on Public Transport (England) Regulations 2020
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Coronavirus, Restrictions (No. 2) (England) Regulations 2020
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Coronavirus, Restrictions (Steps) (England) Regulations 2021
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Coronavirus, International Travel (England) Regulations 2020
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New and Emerging Respiratory Virus Threats Advisory Group
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COVID-19 drug repurposing research § Dexamethasone
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RECOVERY trial chief investigators (15 January 2021).
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Mortality over 28 days for 1007 COVID-19 patients on
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at time of randomisation: 324 patients who received
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National Institutes of Health. 25 June 2020 2558: 2556: 2554: 1760: 8: 5075:Hold Still: A Portrait of Our Nation in 2020 4353:Corporate Insolvency and Governance Act 2020 4275:Vaccines Manufacturing and Innovation Centre 3931:Saint Helena, Ascension and Tristan da Cunha 3353:RECOVERY Collaborative Group (14 May 2021). 2724:. UK Research and Innovation. Archived from 4318:Public Health (Control of Disease) Act 1984 3514:RECOVERY Collaborative Group (1 May 2021). 3208:: CS1 maint: numeric names: authors list ( 2506: 2504: 1799:infection. The trial was later expanded to 5281:Medical responses to the COVID-19 pandemic 4858: 4519: 4413:First COVID-19 tier regulations in England 4310: 4303: 4142: 3980: 3800: 3695: 3681: 3673: 3660: 2615: 2613: 2565:"At last some good news about coronavirus" 2528: 2526: 1767: 1753: 142: 4762:Scientific Advisory Group for Emergencies 3626: 3549: 3539: 3490: 3480: 3386: 3329: 3319: 3278: 3248: 3185: 3096: 2946: 2849: 2839: 2806: 2427: 1791:of possible treatments for people in the 1781:Randomised Evaluation of COVID-19 Therapy 2260:released as a preprint on the same day. 5271:COVID-19 pandemic in the United Kingdom 5221: 4737:Imperial College COVID-19 Response Team 4268:European Commission–AstraZeneca dispute 3704:COVID-19 pandemic in the United Kingdom 3668:Trial Protocol (v12.1) dated 2020-12-16 2324: 1493:Neurological and psychological symptoms 154: 5156:COVID-19 Bereaved Families for Justice 3201: 2460:"International sites — RECOVERY Trial" 2238:in people hospitalized with COVID-19. 2175:John Fletcher, research editor at the 2054:National Institute for Health Research 1999:(used to treat malaria and rheumatism) 16:Test of existing medicines on COVID-19 3436:Michelle Roberts (11 February 2021). 1913:may also be allocated the following: 1888:(adults only, early phase assessment) 1831:The RECOVERY Trial is a large-scale, 7: 4577:Cabinet Secretary for Covid Recovery 2212:Confirmation of dexamethasone result 5276:Clinical trials related to COVID-19 4263:Oxford–AstraZeneca COVID-19 vaccine 2202:Responding to the publication, the 2159:Limitations of dexamethasone result 2122:The New England Journal of Medicine 4591:Coughs and sneezes spread diseases 4066:Privileges Committee investigation 2539:. RECOVERY Trial. 21 November 2020 14: 3573:Nicola Davis (11 February 2021). 3112:Roni Caryn Rabin (24 June 2020). 2975:NIH COVID-19 Treatment Guidelines 1795:admitted to hospital with severe 5248: 5236: 5224: 5198: 4532:Coronavirus Job Retention Scheme 1736: 122: 30: 4117:COVID-19 Genomics UK Consortium 2828:New England Journal of Medicine 2766:Kupferschmidt K (2 July 2020). 2033:(a commonly used blood thinner) 4572:Can you look them in the eyes? 4358:Business and Planning Act 2020 3896:British Indian Ocean Territory 58:add the appropriate references 1: 3532:10.1016/S0140-6736(21)00676-0 3482:10.1016/S0140-6736(21)00712-1 3463:Gupta S, Leaf DE (May 2021). 3371:10.1016/S0140-6736(21)00897-7 3312:10.1016/S0140-6736(21)00149-5 3280:10.1101/2020.12.10.20245944v1 3241:10.1016/S0140-6736(20)32013-4 3098:10.1101/2020.07.29.20164269v1 2808:10.1101/2020.06.22.20137273v1 2590:"Recovery Trial Protocol v15" 2563:Fergus Walsh (20 June 2020). 2511:Gallagher J (25 March 2021). 2145:National Institutes of Health 5186:National Covid Memorial Wall 3712:British Overseas Territories 2056:(NIHR). The study is led by 1517:Alzheimer's disease patients 1042:Misinformation and hesitancy 4557:National Tutoring Programme 4333:Contingencies Fund Act 2021 4328:Contingencies Fund Act 2020 3141:. World Health Organization 2996:hermesauto (22 July 2020). 2900:"Dexamethasone in COVID-19" 1833:randomized controlled trial 43:reliable medical references 5302: 4013:National Day of Reflection 3619:10.1038/s41467-023-43644-x 2747:Boseley S (17 June 2020). 2227: 2084: 18: 5194: 5151:Coronavirus Tech Handbook 4596:Catch It, Bin It, Kill It 4313: 4112:Cancer Monitoring Project 4078:Scottish COVID-19 Inquiry 3718: 2429:10.1038/s41587-020-0528-x 2313:COVID-19 drug development 826:World Health Organization 49:or relies too heavily on 4747:Joint Biosecurity Centre 4245:UK Rapid Test Consortium 4083:Virtual House of Commons 4041:Dominic Cummings scandal 3973:Exam grading controversy 3936:Turks and Caicos Islands 1787:) is a large-enrollment 996:Public health mitigation 680:By country and territory 19:Not to be confused with 4582:Pre-pandemic exercises 4552:Global Travel Taskforce 4338:Coronavirus mini-budget 4056:Northern Research Group 3178:10.1001/jama.2020.17023 2422:(5): 510. 11 May 2020. 1841:adaptive clinical trial 1498:Post-exertional malaise 838:Undercounting of deaths 5161:Death of Belly Mujinga 4537:Contract controversies 3901:British Virgin Islands 2929:Mahase E (June 2020). 2488:Clinical trial number 2190:immunosuppressive drug 2172: 2135:Chief Medical Officers 2104: 2097:mechanical ventilation 2039:(a drug used for gout) 1947:(an anti-inflammatory) 1941:(an anti-inflammatory) 1656:Science and technology 1532:Death rates by country 746:International response 168: 140: 5176:London Blossom Garden 4368:Culture Recovery Fund 4255:Vaccination programme 3961:Cost-of-living crisis 3881:Akrotiri and Dhekelia 3606:Nature Communications 2841:10.1056/NEJMoa2021436 2464:www.recoverytrial.net 2166: 2094: 2052:and supported by the 1681:Xenophobia and racism 1547:Emergency evacuations 166: 138: 4936:Catherine Calderwood 4619:Overseas territories 4468:Coronavirus Act 2020 4229:Test, Trace, Protect 4036:COVID Recovery Group 3873:Overseas Territories 3526:(10285): 1637–1645. 3475:(10285): 1599–1601. 3365:(10289): 2049–2059. 3235:(10259): 1345–1352. 2878:University of Oxford 2416:Nature Biotechnology 2050:University of Oxford 1817:newly developed drug 1416:Association football 1037:Operation Warp Speed 5205:COVID-19 portal 5029:"Can You Hear Me" ( 4547:Eat Out to Help Out 4343:Winter Economy Plan 4147:Temporary hospitals 4122:COVID Symptom Study 4107:Antiviral Taskforce 3993:Clap for Our Carers 2264:Convalescent plasma 2251:on 5 October 2020. 2242:Lopinavir-ritonavir 2013:Convalescent plasma 1821:convalescent plasma 1614:Other health issues 1141:Variants of concern 139:RECOVERY Trial logo 5061:Grayson's Art Club 4647:July–December 2020 4235:Operation Moonshot 4223:NHS Test and Trace 3845:Crown Dependencies 3708:Crown Dependencies 3417:. 11 February 2021 3306:(10274): 605–612. 2728:on 24 October 2020 2496:ClinicalTrials.gov 2236:hydroxychloroquine 2224:Hydroxychloroquine 2173: 2105: 1997:Hydroxychloroquine 1106:Oxford–AstraZeneca 944:federal government 855:National responses 169: 141: 21:RECOVER Initiative 5212: 5211: 5146:Captain Tom Moore 5082:Isolation Stories 5054:Failures of State 5015: 5014: 4905:Charlotte McArdle 4663:Northern Ireland 4642:January–June 2020 4627: 4626: 4509: 4508: 4381: 4380: 4363:Nightingale Court 4293: 4292: 4210:Testing programme 4091: 4090: 4046:Greensill scandal 4008:The 2.6 Challenge 3944: 3943: 3172:(13): 1330–1341. 3002:The Straits Times 2948:10.1136/bmj.m2512 2681:. RECOVERY Trial. 2289:Dimethyl fumarate 1886:Dimethyl fumarate 1777: 1776: 1542:Domestic violence 1451:Gridiron football 1286:Financial markets 1059:Vaccine passports 806:Social distancing 767:International aid 156:COVID-19 pandemic 131: 130: 107: 5293: 5253: 5252: 5241: 5240: 5229: 5228: 5227: 5220: 5203: 5202: 5101:Pandemic Diaries 4915:Michelle O'Neill 4888:Northern Ireland 4874:Amanda Pritchard 4859: 4843:Jonathan Van-Tam 4838:Patrick Vallance 4742:Independent SAGE 4562:Pick for Britain 4520: 4311: 4304: 4218:NHS COVID-19 app 4143: 4051:Impact on Brexit 3981: 3926:Pitcairn Islands 3911:Falkland Islands 3825:Northern Ireland 3801: 3697: 3690: 3683: 3674: 3664: 3659: 3658: 3656:Official website 3641: 3640: 3630: 3596: 3590: 3589: 3587: 3585: 3570: 3564: 3563: 3553: 3543: 3511: 3505: 3504: 3494: 3484: 3460: 3454: 3453: 3451: 3449: 3433: 3427: 3426: 3424: 3422: 3407: 3401: 3400: 3390: 3350: 3344: 3343: 3333: 3323: 3291: 3285: 3284: 3282: 3269: 3263: 3262: 3252: 3220: 3214: 3213: 3207: 3199: 3189: 3157: 3151: 3150: 3148: 3146: 3135: 3129: 3128: 3126: 3124: 3109: 3103: 3102: 3100: 3088: 3082: 3081: 3079: 3077: 3063: 3057: 3056: 3045: 3039: 3038: 3036: 3034: 3019: 3013: 3012: 3010: 3008: 2993: 2987: 2986: 2984: 2982: 2967: 2961: 2960: 2950: 2926: 2915: 2914: 2912: 2910: 2904: 2896: 2890: 2889: 2887: 2885: 2870: 2864: 2863: 2853: 2843: 2819: 2813: 2812: 2810: 2798: 2783: 2782: 2780: 2778: 2763: 2757: 2756: 2744: 2738: 2737: 2735: 2733: 2714: 2708: 2707: 2705: 2703: 2692: 2683: 2682: 2674: 2663: 2662: 2660: 2658: 2647: 2636: 2635: 2633: 2631: 2625: 2617: 2608: 2607: 2605: 2603: 2594: 2586: 2580: 2579: 2577: 2575: 2560: 2549: 2548: 2546: 2544: 2538: 2530: 2521: 2520: 2508: 2499: 2486: 2475: 2474: 2472: 2470: 2456: 2450: 2449: 2431: 2408: 2399: 2398: 2396: 2394: 2379: 2373: 2372: 2370: 2368: 2362:"RECOVERY Trial" 2358: 2341: 2340: 2329: 2303:Solidarity trial 1925:, which reduces 1813:repurposed drugs 1769: 1762: 1755: 1741: 1740: 1249:Arts and culture 1065:Current vaccines 991:Drug repurposing 986:Drug development 963:Medical response 143: 126: 125: 117: 114: 108: 106: 72:"RECOVERY Trial" 65: 34: 33: 26: 5301: 5300: 5296: 5295: 5294: 5292: 5291: 5290: 5261: 5260: 5259: 5247: 5235: 5225: 5223: 5215: 5213: 5208: 5197: 5190: 5181:Lineage B.1.1.7 5134: 5047:Emergency State 5021: 5011: 5002:Vaughan Gething 4980: 4966:Nicola Sturgeon 4941:Joe FitzPatrick 4924: 4910:Michael McBride 4883: 4857: 4766: 4729: 4723: 4623: 4602: 4586:Exercise Cygnus 4505: 4478: 4472: 4377: 4289: 4249: 4240:Test to Release 4204: 4141: 4137:PANORAMIC trial 4127:COVID passports 4099: 4097: 4087: 4017: 3979: 3940: 3867: 3839: 3792: 3714: 3701: 3654: 3653: 3650: 3645: 3644: 3598: 3597: 3593: 3583: 3581: 3572: 3571: 3567: 3513: 3512: 3508: 3462: 3461: 3457: 3447: 3445: 3442:BBC News Online 3435: 3434: 3430: 3420: 3418: 3409: 3408: 3404: 3352: 3351: 3347: 3293: 3292: 3288: 3271: 3270: 3266: 3222: 3221: 3217: 3200: 3159: 3158: 3154: 3144: 3142: 3137: 3136: 3132: 3122: 3120: 3111: 3110: 3106: 3090: 3089: 3085: 3075: 3073: 3065: 3064: 3060: 3047: 3046: 3042: 3032: 3030: 3029:. 4 August 2020 3021: 3020: 3016: 3006: 3004: 2995: 2994: 2990: 2980: 2978: 2969: 2968: 2964: 2928: 2927: 2918: 2908: 2906: 2902: 2898: 2897: 2893: 2883: 2881: 2872: 2871: 2867: 2821: 2820: 2816: 2800: 2799: 2786: 2776: 2774: 2765: 2764: 2760: 2746: 2745: 2741: 2731: 2729: 2716: 2715: 2711: 2701: 2699: 2694: 2693: 2686: 2676: 2675: 2666: 2656: 2654: 2649: 2648: 2639: 2629: 2627: 2623: 2619: 2618: 2611: 2601: 2599: 2592: 2588: 2587: 2583: 2573: 2571: 2562: 2561: 2552: 2542: 2540: 2536: 2532: 2531: 2524: 2510: 2509: 2502: 2487: 2478: 2468: 2466: 2458: 2457: 2453: 2410: 2409: 2402: 2392: 2390: 2381: 2380: 2376: 2366: 2364: 2360: 2359: 2344: 2331: 2330: 2326: 2321: 2308:PANORAMIC trial 2299: 2291: 2275: 2266: 2257: 2244: 2232: 2226: 2214: 2161: 2131: 2089: 2083: 2078: 2046: 1873: 1862: 1853: 1829: 1773: 1743:COVID-19 portal 1735: 1730: 1729: 1644:Catholic Church 1619:Popular culture 1481: 1471: 1470: 1311:Performing arts 1244: 1238:Economic impact 1230: 1229: 1225:Lineage B.1.617 1136: 1126: 1125: 1111:Pfizer–BioNTech 969:Disease testing 964: 956: 955: 799:Fake treatments 747: 739: 738: 675: 665: 664: 209: 127: 123: 118: 112: 109: 66: 55: 51:primary sources 35: 31: 24: 17: 12: 11: 5: 5299: 5297: 5289: 5288: 5283: 5278: 5273: 5263: 5262: 5258: 5257: 5245: 5233: 5210: 5209: 5195: 5192: 5191: 5189: 5188: 5183: 5178: 5173: 5171:Notable deaths 5168: 5163: 5158: 5153: 5148: 5142: 5140: 5136: 5135: 5133: 5132: 5125: 5118: 5111: 5104: 5097: 5095:Lockdown Files 5092: 5085: 5078: 5071: 5064: 5057: 5050: 5043: 5035: 5025: 5023: 5017: 5016: 5013: 5012: 5010: 5009: 5004: 4999: 4997:Mark Drakeford 4994: 4992:Frank Atherton 4988: 4986: 4982: 4981: 4979: 4978: 4973: 4968: 4963: 4958: 4953: 4948: 4943: 4938: 4932: 4930: 4926: 4925: 4923: 4922: 4917: 4912: 4907: 4902: 4897: 4891: 4889: 4885: 4884: 4882: 4881: 4876: 4871: 4865: 4863: 4856: 4855: 4850: 4845: 4840: 4835: 4830: 4825: 4820: 4815: 4810: 4805: 4800: 4795: 4790: 4785: 4780: 4774: 4772: 4768: 4767: 4765: 4764: 4759: 4754: 4749: 4744: 4739: 4733: 4731: 4725: 4724: 4722: 4721: 4720: 4719: 4714: 4709: 4701: 4700: 4699: 4694: 4689: 4681: 4680: 4679: 4674: 4669: 4661: 4660: 4659: 4654: 4649: 4644: 4635: 4633: 4629: 4628: 4625: 4624: 4622: 4621: 4616: 4614:United Kingdom 4610: 4608: 4604: 4603: 4601: 4600: 4599: 4598: 4593: 4588: 4580: 4574: 4569: 4564: 4559: 4554: 4549: 4544: 4539: 4534: 4528: 4526: 4517: 4511: 4510: 4507: 4506: 4504: 4503: 4498: 4493: 4488: 4482: 4480: 4474: 4473: 4471: 4470: 4465: 4460: 4455: 4450: 4445: 4440: 4435: 4430: 4425: 4420: 4415: 4410: 4405: 4400: 4395: 4389: 4387: 4383: 4382: 4379: 4378: 4376: 4375: 4370: 4365: 4360: 4355: 4350: 4345: 4340: 4335: 4330: 4325: 4320: 4314: 4308: 4301: 4295: 4294: 4291: 4290: 4288: 4287: 4282: 4277: 4272: 4271: 4270: 4259: 4257: 4251: 4250: 4248: 4247: 4242: 4237: 4232: 4226: 4220: 4214: 4212: 4206: 4205: 4203: 4202: 4197: 4192: 4187: 4182: 4181: 4180: 4175: 4170: 4165: 4160: 4151: 4149: 4140: 4139: 4134: 4132:RECOVERY Trial 4129: 4124: 4119: 4114: 4109: 4103: 4101: 4093: 4092: 4089: 4088: 4086: 4085: 4080: 4075: 4073:Public inquiry 4070: 4069: 4068: 4058: 4053: 4048: 4043: 4038: 4033: 4027: 4025: 4019: 4018: 4016: 4015: 4010: 4005: 4000: 3995: 3989: 3987: 3978: 3977: 3976: 3975: 3965: 3964: 3963: 3952: 3950: 3946: 3945: 3942: 3941: 3939: 3938: 3933: 3928: 3923: 3918: 3913: 3908: 3906:Cayman Islands 3903: 3898: 3893: 3888: 3883: 3877: 3875: 3869: 3868: 3866: 3865: 3860: 3855: 3849: 3847: 3841: 3840: 3838: 3837: 3832: 3827: 3822: 3821: 3820: 3809: 3807: 3805:United Kingdom 3798: 3794: 3793: 3791: 3790: 3789: 3788: 3783: 3778: 3777: 3776: 3771: 3763: 3762: 3761: 3756: 3748: 3747: 3746: 3741: 3730: 3725: 3719: 3716: 3715: 3702: 3700: 3699: 3692: 3685: 3677: 3671: 3670: 3665: 3649: 3648:External links 3646: 3643: 3642: 3591: 3565: 3506: 3455: 3428: 3415:Recovery Trial 3402: 3345: 3286: 3264: 3215: 3152: 3130: 3118:New York Times 3104: 3083: 3058: 3040: 3014: 2988: 2962: 2916: 2905:. 16 June 2020 2891: 2880:. 16 June 2020 2865: 2834:(8): 693–704. 2814: 2784: 2758: 2739: 2709: 2684: 2664: 2637: 2609: 2597:Recovery Trial 2581: 2550: 2522: 2500: 2476: 2451: 2400: 2389:. 17 June 2020 2374: 2342: 2337:www.isrctn.com 2323: 2322: 2320: 2317: 2316: 2315: 2310: 2305: 2298: 2295: 2290: 2287: 2274: 2271: 2265: 2262: 2256: 2253: 2243: 2240: 2228:Main article: 2225: 2222: 2213: 2210: 2209: 2208: 2200: 2193: 2186: 2160: 2157: 2130: 2127: 2117:oxygen therapy 2082: 2079: 2077: 2074: 2062:Martin Landray 2045: 2042: 2041: 2040: 2034: 2028: 2010: 2000: 1994: 1976: 1975: 1970: 1964: 1959: 1949: 1948: 1942: 1936: 1934:immunoglobulin 1930: 1909:Children with 1907: 1906: 1895: 1889: 1883: 1872: 1869: 1861: 1858: 1852: 1849: 1828: 1825: 1793:United Kingdom 1789:clinical trial 1785:RECOVERY Trial 1775: 1774: 1772: 1771: 1764: 1757: 1749: 1746: 1745: 1732: 1731: 1728: 1727: 1722: 1717: 1712: 1707: 1702: 1697: 1691: 1690: 1684: 1683: 1678: 1673: 1668: 1663: 1658: 1653: 1652: 1651: 1646: 1636: 1631: 1626: 1621: 1616: 1611: 1609:Notable deaths 1606: 1601: 1596: 1591: 1589:Media coverage 1586: 1584:Long-term care 1581: 1579:LGBT community 1576: 1571: 1566: 1561: 1560: 1559: 1549: 1544: 1539: 1534: 1529: 1524: 1519: 1514: 1508: 1507: 1501: 1500: 1495: 1489: 1488: 1482: 1477: 1476: 1473: 1472: 1469: 1468: 1463: 1458: 1453: 1448: 1443: 1438: 1433: 1428: 1423: 1418: 1412: 1411: 1405: 1404: 1399: 1394: 1389: 1384: 1379: 1374: 1369: 1363: 1362: 1358: 1357: 1352: 1347: 1346: 1345: 1344: 1343: 1338: 1323: 1318: 1313: 1308: 1303: 1298: 1293: 1288: 1283: 1278: 1273: 1272: 1271: 1261: 1256: 1251: 1245: 1236: 1235: 1232: 1231: 1228: 1227: 1222: 1217: 1212: 1207: 1202: 1197: 1192: 1187: 1182: 1176: 1175: 1174:Other variants 1171: 1170: 1165: 1160: 1155: 1150: 1144: 1143: 1137: 1132: 1131: 1128: 1127: 1124: 1123: 1118: 1116:Sinopharm BIBP 1113: 1108: 1103: 1098: 1093: 1088: 1083: 1078: 1073: 1067: 1066: 1062: 1061: 1056: 1051: 1050: 1049: 1039: 1034: 1032:Authorizations 1029: 1024: 1023: 1022: 1012: 1006: 1005: 999: 998: 993: 988: 983: 982: 981: 976: 965: 962: 961: 958: 957: 954: 953: 948: 947: 946: 936: 935: 934: 924: 919: 914: 909: 904: 899: 894: 889: 884: 879: 874: 872:European Union 869: 864: 858: 857: 851: 850: 845: 840: 835: 830: 829: 828: 821:United Nations 818: 813: 808: 803: 802: 801: 796: 794:by governments 789:Misinformation 786: 785: 784: 774: 769: 764: 759: 754: 748: 745: 744: 741: 740: 737: 736: 731: 725: 724: 720: 719: 714: 709: 704: 699: 694: 689: 683: 682: 676: 671: 670: 667: 666: 663: 662: 656: 655: 650: 645: 644: 643: 633: 632: 631: 621: 620: 619: 609: 608: 607: 597: 596: 595: 585: 584: 583: 573: 572: 571: 561: 560: 559: 549: 548: 547: 537: 536: 535: 524: 523: 519: 518: 517: 516: 506: 505: 504: 494: 493: 492: 482: 481: 480: 470: 469: 468: 458: 457: 456: 446: 445: 444: 434: 433: 432: 422: 421: 420: 410: 409: 408: 398: 397: 396: 386: 385: 384: 373: 372: 368: 367: 366: 365: 355: 354: 353: 343: 342: 341: 331: 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4949: 4947: 4946:Jeane Freeman 4944: 4942: 4939: 4937: 4934: 4933: 4931: 4927: 4921: 4918: 4916: 4913: 4911: 4908: 4906: 4903: 4901: 4898: 4896: 4895:Arlene Foster 4893: 4892: 4890: 4886: 4880: 4879:Simon Stevens 4877: 4875: 4872: 4870: 4869:Stephen Powis 4867: 4866: 4864: 4860: 4854: 4853:Nadhim Zahawi 4851: 4849: 4846: 4844: 4841: 4839: 4836: 4834: 4833:Maggie Throup 4831: 4829: 4826: 4824: 4821: 4819: 4816: 4814: 4811: 4809: 4808:Boris Johnson 4806: 4804: 4801: 4799: 4798:Jenny Harries 4796: 4794: 4791: 4789: 4786: 4784: 4783:Neil Ferguson 4781: 4779: 4776: 4775: 4773: 4769: 4763: 4760: 4758: 4755: 4753: 4750: 4748: 4745: 4743: 4740: 4738: 4735: 4734: 4732: 4726: 4718: 4715: 4713: 4710: 4708: 4705: 4704: 4702: 4698: 4695: 4693: 4690: 4688: 4685: 4684: 4682: 4678: 4675: 4673: 4670: 4668: 4665: 4664: 4662: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4639: 4637: 4636: 4634: 4630: 4620: 4617: 4615: 4612: 4611: 4609: 4605: 4597: 4594: 4592: 4589: 4587: 4584: 4583: 4581: 4578: 4575: 4573: 4570: 4568: 4567:Project Birch 4565: 4563: 4560: 4558: 4555: 4553: 4550: 4548: 4545: 4543: 4540: 4538: 4535: 4533: 4530: 4529: 4527: 4525: 4521: 4518: 4516: 4512: 4502: 4499: 4497: 4494: 4492: 4489: 4487: 4484: 4483: 4481: 4475: 4469: 4466: 4464: 4461: 4459: 4456: 4454: 4451: 4449: 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4401: 4399: 4396: 4394: 4391: 4390: 4388: 4384: 4374: 4371: 4369: 4366: 4364: 4361: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4319: 4316: 4315: 4312: 4309: 4305: 4302: 4300: 4296: 4286: 4283: 4281: 4278: 4276: 4273: 4269: 4266: 4265: 4264: 4261: 4260: 4258: 4256: 4252: 4246: 4243: 4241: 4238: 4236: 4233: 4230: 4227: 4224: 4221: 4219: 4216: 4215: 4213: 4211: 4207: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4179: 4176: 4174: 4171: 4169: 4166: 4164: 4161: 4159: 4156: 4155: 4153: 4152: 4150: 4148: 4144: 4138: 4135: 4133: 4130: 4128: 4125: 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Index

RECOVER Initiative
reliable medical references
verification
primary sources
add the appropriate references
removed
"RECOVERY Trial"
news
newspapers
books
scholar
JSTOR
RECOVERY: Randomized Evaluation of COVID-19 Therapy
a series
COVID-19 pandemic
Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
COVID-19
SARS-CoV-2
Cases
Deaths
Timeline
2019
January
responses
February
responses
March
responses
April
responses

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