Knowledge (XXG)

Ralpancizumab

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369: 441: 434: 427: 84: 410: 319:"A Phase I Randomized Study of a Specifically Engineered, pH-Sensitive PCSK9 Inhibitor RN317 (PF-05335810) in Hypercholesterolemic Subjects on Statin Therapy" 34: 1027: 403: 983: 1032: 396: 227: 1037: 419: 514: 302: 141: 1000: 450: 262: 266: 639: 634: 988: 895: 291: 376: 105: 44: 27: 871: 773: 672: 543: 267:"International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 110" 348: 380: 114: 680: 338: 330: 166: 150: 994: 649: 343: 318: 317:
Levisetti M, Joh T, Wan H, Liang H, Forgues P, Gumbiner B, Garzone PD (January 2017).
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for bone, musculoskeletal, circulatory, and neurologic systems
299:
Statement On A Nonproprietary Name Adopted By The USAN Council
234:) is a monoclonal antibody designed for the treatment of 384: 953: 932: 923: 903: 894: 824: 766: 757: 671: 648: 627: 551: 542: 522: 513: 488: 467: 458: 204: 165: 160: 140: 124: 104: 99: 83: 75: 70: 60: 43: 33: 26: 113: 435: 404: 8: 19: 929: 900: 763: 548: 519: 464: 442: 428: 420: 411: 397: 342: 149: 254: 66:neural apoptosis-regulated proteinase 1 18: 7: 365: 363: 383:. You can help Knowledge (XXG) by 323:Clinical and Translational Science 14: 367: 183: 177: 1028:Drugs not assigned an ATC code 195: 189: 171: 1: 303:American Medical Association 241:This drug was developed by 1054: 362: 161:Chemical and physical data 1033:Monoclonal antibody stubs 978: 263:World Health Organization 896:Angiogenesis inhibitor 379:–related article is a 1038:Monoclonal antibodies 274:WHO Drug Information 377:monoclonal antibody 230:; development code 28:Monoclonal antibody 23: 16:Monoclonal antibody 1005:Never to phase III 774:Anti-amyloid drugs 1015: 1014: 974: 973: 919: 918: 890: 889: 753: 752: 538: 537: 509: 508: 392: 391: 335:10.1111/cts.12430 221: 220: 1045: 930: 901: 764: 681:Alacizumab pegol 549: 520: 465: 444: 437: 430: 421: 413: 406: 399: 371: 364: 357: 356: 346: 314: 308: 306: 296: 288: 282: 281: 271: 259: 216: 214: 197: 191: 185: 179: 173: 153: 117: 24: 22: 1053: 1052: 1048: 1047: 1046: 1044: 1043: 1042: 1018: 1017: 1016: 1011: 1010: 995:Clinical trials 970: 949: 915: 886: 820: 749: 667: 644: 623: 534: 515:Musculoskeletal 505: 484: 454: 448: 418: 417: 361: 360: 316: 315: 311: 294: 292:"Ralpancizumab" 290: 289: 285: 269: 261: 260: 256: 251: 212: 210: 200: 194: 188: 182: 176: 156: 136: 120: 95: 17: 12: 11: 5: 1051: 1049: 1041: 1040: 1035: 1030: 1020: 1019: 1013: 1012: 1009: 1008: 1007: 1006: 1003: 992: 986: 980: 979: 976: 975: 972: 971: 969: 968: 963: 957: 955: 951: 950: 948: 947: 942: 936: 934: 927: 921: 920: 917: 916: 914: 913: 907: 905: 898: 892: 891: 888: 887: 885: 884: 879: 874: 869: 864: 859: 854: 849: 844: 839: 834: 828: 826: 822: 821: 819: 818: 813: 808: 803: 798: 797: 796: 791: 786: 781: 770: 768: 761: 755: 754: 751: 750: 748: 747: 742: 737: 732: 727: 722: 717: 712: 707: 702: 697: 692: 683: 677: 675: 669: 668: 666: 665: 660: 654: 652: 646: 645: 643: 642: 637: 631: 629: 625: 624: 622: 621: 616: 611: 606: 601: 596: 591: 586: 581: 576: 571: 566: 561: 555: 553: 546: 540: 539: 536: 535: 533: 532: 526: 524: 517: 511: 510: 507: 506: 504: 503: 498: 492: 490: 486: 485: 483: 482: 477: 471: 469: 462: 456: 455: 449: 447: 446: 439: 432: 424: 416: 415: 408: 401: 393: 390: 389: 372: 359: 358: 309: 283: 253: 252: 250: 247: 219: 218: 208: 202: 201: 198: 192: 186: 180: 174: 169: 163: 162: 158: 157: 155: 154: 146: 144: 138: 137: 135: 134: 130: 128: 122: 121: 119: 118: 110: 108: 102: 101: 97: 96: 94: 93: 89: 87: 81: 80: 77: 73: 72: 68: 67: 64: 58: 57: 47: 41: 40: 37: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 1050: 1039: 1036: 1034: 1031: 1029: 1026: 1025: 1023: 1004: 1002: 999: 998: 996: 993: 990: 987: 985: 982: 981: 977: 967: 966:Landogrozumab 964: 962: 959: 958: 956: 952: 946: 943: 941: 938: 937: 935: 931: 928: 926: 925:Growth factor 922: 912: 909: 908: 906: 902: 899: 897: 893: 883: 880: 878: 875: 873: 870: 868: 865: 863: 860: 858: 855: 853: 850: 848: 845: 843: 840: 838: 835: 833: 830: 829: 827: 823: 817: 814: 812: 809: 807: 804: 802: 799: 795: 792: 790: 787: 785: 782: 780: 777: 776: 775: 772: 771: 769: 765: 762: 760: 756: 746: 743: 741: 738: 736: 735:Ralpancizumab 733: 731: 728: 726: 723: 721: 718: 716: 713: 711: 708: 706: 703: 701: 698: 696: 693: 691: 687: 684: 682: 679: 678: 676: 674: 670: 664: 661: 659: 656: 655: 653: 651: 647: 641: 638: 636: 633: 632: 630: 626: 620: 617: 615: 612: 610: 607: 605: 602: 600: 597: 595: 592: 590: 587: 585: 582: 580: 577: 575: 572: 570: 569:Ascrinvacumab 567: 565: 562: 560: 557: 556: 554: 550: 547: 545: 541: 531: 528: 527: 525: 521: 518: 516: 512: 502: 499: 497: 494: 493: 491: 487: 481: 478: 476: 473: 472: 470: 466: 463: 461: 457: 452: 445: 440: 438: 433: 431: 426: 425: 422: 414: 409: 407: 402: 400: 395: 394: 388: 386: 382: 378: 373: 370: 366: 354: 350: 345: 340: 336: 332: 328: 324: 320: 313: 310: 304: 300: 293: 287: 284: 279: 275: 268: 264: 258: 255: 248: 246: 244: 239: 237: 233: 229: 225: 224:Ralpancizumab 209: 207: 203: 170: 168: 164: 159: 152: 148: 147: 145: 143: 139: 132: 131: 129: 127: 123: 116: 112: 111: 109: 107: 103: 98: 91: 90: 88: 86: 82: 78: 74: 71:Clinical data 69: 65: 63: 59: 55: 51: 48: 46: 42: 38: 36: 32: 29: 25: 21:Ralpancizumab 961:Domagrozumab 852:Galcanezumab 847:Fremanezumab 832:Bapineuzumab 789:Gantenerumab 734: 730:Idarucizumab 720:Etaracizumab 705:Caplacizumab 700:Brolucizumab 385:expanding it 374: 326: 322: 312: 298: 286: 277: 273: 257: 240: 236:dyslipidemia 231: 223: 222: 115:1407495-04-8 991:from market 945:Trevogrumab 911:Ranibizumab 877:Solanezumab 872:Semorinemab 867:Refanezumab 842:Eptinezumab 745:Vanucizumab 740:Tadocizumab 695:Bococizumab 690:Ranibizumab 686:Bevacizumab 663:Volociximab 614:Ramucirumab 574:Bentracimab 544:Circulatory 501:Romosozumab 451:Monoclonals 329:(1): 3–11. 217: g·mol 100:Identifiers 76:Other names 1022:Categories 940:Bimagrumab 857:Ozanezumab 837:Crenezumab 816:Opicinumab 811:Fulranumab 779:Aducanumab 759:Neurologic 715:Emicizumab 710:Demcizumab 604:Nesvacumab 599:Inclacumab 589:Evolocumab 584:Evinacumab 579:Enoticumab 564:Alirocumab 559:Abelacimab 530:Stamulumab 496:Blosozumab 249:References 206:Molar mass 151:YB9L51E4MD 126:ChemSpider 106:CAS Number 1001:Phase III 989:Withdrawn 954:Humanized 904:Humanized 882:Tanezumab 862:Ponezumab 825:Humanized 806:Fasinumab 794:Lecanemab 784:Donanemab 725:Faricimab 673:Humanized 658:Abciximab 640:Imciromab 635:Biciromab 619:Rinucumab 609:Orticumab 594:Icrucumab 489:Humanized 480:Denosumab 475:Burosumab 50:Humanized 801:Erenumab 650:Chimeric 353:27860267 265:(2013). 85:ATC code 344:5351011 167:Formula 984:WHO-EM 351:  341:  243:Pfizer 62:Target 52:(from 45:Source 933:Human 767:Human 628:Mouse 552:Human 523:Human 468:Human 375:This 295:(PDF) 270:(PDF) 232:RN317 79:RN317 54:mouse 460:Bone 381:stub 349:PMID 280:(4). 193:2012 187:1730 181:9922 175:6422 142:UNII 133:none 92:none 35:Type 339:PMC 331:doi 228:INN 215:.36 213:289 211:145 1024:: 997:: 347:. 337:. 327:10 325:. 321:. 301:. 297:. 278:27 276:. 272:. 245:. 238:. 199:54 688:/ 443:e 436:t 429:v 412:e 405:t 398:v 387:. 355:. 333:: 307:. 305:. 226:( 196:S 190:O 184:N 178:H 172:C 56:) 39:?

Index

Monoclonal antibody
Type
Source
Humanized
mouse
Target
ATC code
CAS Number
1407495-04-8
ChemSpider
UNII
YB9L51E4MD
Formula
Molar mass
INN
dyslipidemia
Pfizer
World Health Organization
"International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 110"
"Ralpancizumab"
American Medical Association
"A Phase I Randomized Study of a Specifically Engineered, pH-Sensitive PCSK9 Inhibitor RN317 (PF-05335810) in Hypercholesterolemic Subjects on Statin Therapy"
doi
10.1111/cts.12430
PMC
5351011
PMID
27860267
Stub icon
monoclonal antibody

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