Knowledge (XXG)

Refanezumab

Source 📝

332: 404: 397: 390: 84: 373: 34: 990: 366: 946: 995: 359: 1000: 382: 477: 265: 141: 963: 413: 602: 597: 951: 858: 282:"Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients" 339: 254: 105: 44: 27: 834: 736: 635: 506: 311: 343: 114: 643: 301: 293: 166: 150: 234: 957: 612: 306: 281: 984: 928: 887: 697: 531: 230:) is a monoclonal antibody designed for the recovery of motor function after stroke. 923: 814: 809: 794: 751: 692: 682: 667: 662: 297: 907: 873: 839: 804: 707: 702: 657: 652: 648: 625: 576: 536: 463: 902: 819: 799: 778: 773: 741: 677: 672: 566: 561: 551: 546: 541: 526: 521: 492: 458: 331: 205: 125: 844: 824: 768: 756: 746: 721: 687: 620: 581: 571: 556: 442: 437: 49: 20: 315: 763: 61: 280:
Cramer SC, Enney LA, Russell CK, Simeoni M, Thompson TR (March 2017).
53: 422: 386: 416:
for bone, musculoskeletal, circulatory, and neurologic systems
262:
Statement On A Nonproprietary Name Adopted By The USAN Council
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You can help Knowledge (XXG) by 14: 330: 183: 177: 991:Drugs not assigned an ATC code 195: 189: 171: 66:myelin-associated glycoprotein 1: 298:10.1161/STROKEAHA.116.014517 266:American Medical Association 233:This drug was developed by 1017: 325: 161:Chemical and physical data 996:Monoclonal antibody stubs 941: 859:Angiogenesis inhibitor 342:–related article is a 1001:Monoclonal antibodies 340:monoclonal antibody 28:Monoclonal antibody 23: 16:Monoclonal antibody 968:Never to phase III 737:Anti-amyloid drugs 978: 977: 937: 936: 882: 881: 853: 852: 716: 715: 501: 500: 472: 471: 355: 354: 221: 220: 1008: 893: 864: 727: 644:Alacizumab pegol 512: 483: 428: 407: 400: 393: 384: 376: 369: 362: 334: 327: 320: 319: 309: 277: 271: 269: 259: 251: 216: 214: 197: 191: 185: 179: 173: 153: 117: 24: 22: 1016: 1015: 1011: 1010: 1009: 1007: 1006: 1005: 981: 980: 979: 974: 973: 958:Clinical trials 933: 912: 878: 849: 783: 712: 630: 607: 586: 497: 478:Musculoskeletal 468: 447: 417: 411: 381: 380: 324: 323: 279: 278: 274: 257: 253: 252: 248: 243: 235:GlaxoSmithKline 212: 210: 200: 194: 188: 182: 176: 156: 136: 120: 95: 17: 12: 11: 5: 1014: 1012: 1004: 1003: 998: 993: 983: 982: 976: 975: 972: 971: 970: 969: 966: 955: 949: 943: 942: 939: 938: 935: 934: 932: 931: 926: 920: 918: 914: 913: 911: 910: 905: 899: 897: 890: 884: 883: 880: 879: 877: 876: 870: 868: 861: 855: 854: 851: 850: 848: 847: 842: 837: 832: 827: 822: 817: 812: 807: 802: 797: 791: 789: 785: 784: 782: 781: 776: 771: 766: 761: 760: 759: 754: 749: 744: 733: 731: 724: 718: 717: 714: 713: 711: 710: 705: 700: 695: 690: 685: 680: 675: 670: 665: 660: 655: 646: 640: 638: 632: 631: 629: 628: 623: 617: 615: 609: 608: 606: 605: 600: 594: 592: 588: 587: 585: 584: 579: 574: 569: 564: 559: 554: 549: 544: 539: 534: 529: 524: 518: 516: 509: 503: 502: 499: 498: 496: 495: 489: 487: 480: 474: 473: 470: 469: 467: 466: 461: 455: 453: 449: 448: 446: 445: 440: 434: 432: 425: 419: 418: 412: 410: 409: 402: 395: 387: 379: 378: 371: 364: 356: 353: 352: 335: 322: 321: 292:(3): 692–698. 272: 245: 244: 242: 239: 219: 218: 208: 202: 201: 198: 192: 186: 180: 174: 169: 163: 162: 158: 157: 155: 154: 146: 144: 138: 137: 135: 134: 130: 128: 122: 121: 119: 118: 110: 108: 102: 101: 97: 96: 94: 93: 89: 87: 81: 80: 77: 73: 72: 68: 67: 64: 58: 57: 47: 41: 40: 37: 31: 30: 15: 13: 10: 9: 6: 4: 3: 2: 1013: 1002: 999: 997: 994: 992: 989: 988: 986: 967: 965: 962: 961: 959: 956: 953: 950: 948: 945: 944: 940: 930: 929:Landogrozumab 927: 925: 922: 921: 919: 915: 909: 906: 904: 901: 900: 898: 894: 891: 889: 888:Growth factor 885: 875: 872: 871: 869: 865: 862: 860: 856: 846: 843: 841: 838: 836: 833: 831: 828: 826: 823: 821: 818: 816: 813: 811: 808: 806: 803: 801: 798: 796: 793: 792: 790: 786: 780: 777: 775: 772: 770: 767: 765: 762: 758: 755: 753: 750: 748: 745: 743: 740: 739: 738: 735: 734: 732: 728: 725: 723: 719: 709: 706: 704: 701: 699: 698:Ralpancizumab 696: 694: 691: 689: 686: 684: 681: 679: 676: 674: 671: 669: 666: 664: 661: 659: 656: 654: 650: 647: 645: 642: 641: 639: 637: 633: 627: 624: 622: 619: 618: 616: 614: 610: 604: 601: 599: 596: 595: 593: 589: 583: 580: 578: 575: 573: 570: 568: 565: 563: 560: 558: 555: 553: 550: 548: 545: 543: 540: 538: 535: 533: 532:Ascrinvacumab 530: 528: 525: 523: 520: 519: 517: 513: 510: 508: 504: 494: 491: 490: 488: 484: 481: 479: 475: 465: 462: 460: 457: 456: 454: 450: 444: 441: 439: 436: 435: 433: 429: 426: 424: 420: 415: 408: 403: 401: 396: 394: 389: 388: 385: 377: 372: 370: 365: 363: 358: 357: 351: 349: 345: 341: 336: 333: 329: 317: 313: 308: 303: 299: 295: 291: 287: 283: 276: 273: 267: 263: 256: 255:"Refanezumab" 250: 247: 240: 238: 236: 231: 229: 225: 209: 207: 203: 170: 168: 164: 159: 152: 148: 147: 145: 143: 139: 132: 131: 129: 127: 123: 116: 112: 111: 109: 107: 103: 98: 91: 90: 88: 86: 82: 78: 74: 71:Clinical data 69: 65: 63: 59: 55: 51: 48: 46: 42: 38: 36: 32: 29: 25: 924:Domagrozumab 829: 815:Galcanezumab 810:Fremanezumab 795:Bapineuzumab 752:Gantenerumab 693:Idarucizumab 683:Etaracizumab 668:Caplacizumab 663:Brolucizumab 348:expanding it 337: 289: 285: 275: 261: 249: 232: 227: 223: 222: 115:1233953-61-1 954:from market 908:Trevogrumab 874:Ranibizumab 840:Solanezumab 835:Semorinemab 830:Refanezumab 805:Eptinezumab 708:Vanucizumab 703:Tadocizumab 658:Bococizumab 653:Ranibizumab 649:Bevacizumab 626:Volociximab 577:Ramucirumab 537:Bentracimab 507:Circulatory 464:Romosozumab 414:Monoclonals 224:Refanezumab 217: g·mol 100:Identifiers 76:Other names 21:Refanezumab 985:Categories 903:Bimagrumab 820:Ozanezumab 800:Crenezumab 779:Opicinumab 774:Fulranumab 742:Aducanumab 722:Neurologic 678:Emicizumab 673:Demcizumab 567:Nesvacumab 562:Inclacumab 552:Evolocumab 547:Evinacumab 542:Enoticumab 527:Alirocumab 522:Abelacimab 493:Stamulumab 459:Blosozumab 241:References 206:Molar mass 151:3ZZ278643V 126:ChemSpider 106:CAS Number 964:Phase III 952:Withdrawn 917:Humanized 867:Humanized 845:Tanezumab 825:Ponezumab 788:Humanized 769:Fasinumab 757:Lecanemab 747:Donanemab 688:Faricimab 636:Humanized 621:Abciximab 603:Imciromab 598:Biciromab 582:Rinucumab 572:Orticumab 557:Icrucumab 452:Humanized 443:Denosumab 438:Burosumab 228:GSK249320 79:GSK249320 50:Humanized 764:Erenumab 613:Chimeric 316:28228578 85:ATC code 307:5325241 167:Formula 947:WHO-EM 314:  304:  286:Stroke 62:Target 52:(from 45:Source 896:Human 730:Human 591:Mouse 515:Human 486:Human 431:Human 338:This 258:(PDF) 181:10156 54:mouse 423:Bone 344:stub 312:PMID 193:2064 187:1732 175:6608 142:UNII 133:none 92:none 35:Type 302:PMC 294:doi 215:.64 213:298 211:148 987:: 960:: 310:. 300:. 290:48 288:. 284:. 264:. 260:. 237:. 199:44 651:/ 406:e 399:t 392:v 375:e 368:t 361:v 350:. 318:. 296:: 270:. 268:. 226:( 196:S 190:O 184:N 178:H 172:C 56:) 39:?

Index

Monoclonal antibody
Type
Source
Humanized
mouse
Target
ATC code
CAS Number
1233953-61-1
ChemSpider
UNII
3ZZ278643V
Formula
Molar mass
GlaxoSmithKline
"Refanezumab"
American Medical Association
"Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients"
doi
10.1161/STROKEAHA.116.014517
PMC
5325241
PMID
28228578
Stub icon
monoclonal antibody
stub
expanding it
v
t

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