25:
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in particular. He was among the first to consider the kinetics of reactions with more than one substrate, and in the years that followed there was hardly any aspect of enzyme kinetics he did not touch, his work including, for example, studies of pH, integrated rate equations, reversible reactions,
359:
Alberty's early interest in the ionization of adenosine phosphates and of thermodynamic aspects of biochemical reactions came to be his primary interest, and in his later years he had numerous publications on this topic, such as a compilation of the properties of
1542:
985:
856:
Alberty, Robert A.; Cornish-Bowden, Athel; Goldberg, Robert N.; Hammes, Gordon G.; Tipton, Keith; Westerhoff, Hans V. (2011). "Recommendations for terminology and databases for biochemical thermodynamics".
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Alberty, Robert A.; Koerber, Barbara M. (1957). "Studies of the Enzyme
Fumarase. VII.1 Series Solutions of Integrated Rate Equations for Irreversible and Reversible Michaelis-Menten Mechanisms2".
978:
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He died in
Cambridge, Massachusetts, at the age of 92 on January 18, 2014. Towards the end of his life he wrote a short account of his life and scientific career.
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Although he was primarily concerned with single enzyme-catalysed reactions, he also did some work with systems of more than one enzyme, such as the urea cycle.
422:
653:
Brant, David A.; Barnett, Lewis B.; Alberty, Robert A. (1963). "The
Temperature Dependence of the Steady State Kinetic Parameters of the Fumarase Reaction".
504:
Alberty, Robert A. (1953). "The
Relationship between Michaelis Constants, Maximum Velocities and the Equilibrium Constant for an Enzyme-catalyzed Reaction".
588:
Alberty, Robert A.; Massey, Vincent (1954). "On the interpretation of the pH variation of the maximum initial velocity of an enzyme-catalyzed reaction".
267:
994:
286:
263:
782:"Standard Gibbs free energy, enthalpy, and entropy changes as a function of pH and pMg for several reactions involving adenosine phosphates"
278:
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Alberty, Robert A.; Goldberg, Robert N. (1992). "Standard thermodynamic formation properties for the adenosine 5'-triphosphate series".
133:
108:
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39:
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Alberty, Robert A.; Anderson, Elmer A.; Williams, J. W. (1948). "Homogenicity and the
Electrophoretic Behavior of Some Proteins".
89:
61:
68:
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955:, MC-0681. Massachusetts Institute of Technology, Department of Distinctive Collections, Cambridge, Massachusetts.
35:
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57:
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Bock, Robert M.; Alberty, Robert A. (1953). "Studies of the Enzyme
Fumarase. I. Kinetics and Equilibrium".
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285:, Alberty was elected to the National Academy of Sciences in 1965. In 1968 he was elected a Fellow of the
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682:"Alteration of the Kinetic Properties of an Enzyme by the Binding of Buffer, Inhibitor, or Substrate"
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Alberty, Robert A. (1958). "On the
Determination of Rate Constants for Coenzyme Mechanisms1".
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Biochemical
Thermodynamics: Applications of Mathematica (Methods of Biochemical Analysis)
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304:, was published in 1957. More recent books of the same title have been co-authored with
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Robert
Alberty, professor emeritus of chemistry and former dean of science, dies at 92
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741:"The apparent ionization constants of the adenosine phosphates and related compounds"
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Alberty, Robert A. (2010). "Brief
Scientific Autobiography of Robert A. Alberty".
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National Academy of Sciences, 1965; American Academy of Arts and Sciences, 1968
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At the beginning of his career Alberty worked principally on aspects of
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on recommendations for presenting data for biochemical thermodynamics.
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effects of temperature, effects of buffers and inhibitors, and others.
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in 1943 and 1944, respectively, then a doctoral degree from the
967:
289:. He was dean of the MIT School of Science between 1967-1982.
18:
1543:
Members of the United States National Academy of Sciences
296:, which have gone through many editions. The first one,
273:
Alberty earned bachelor's and master's degrees from the
894:"Constraints and missing reactions in the urea cycle"
1568:
Fellows of the American Academy of Arts and Sciences
239:
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123:
339:. Later he became increasingly concerned with the
686:Proceedings of the National Academy of Sciences
979:
471:The Journal of Physical and Colloid Chemistry
8:
739:Alberty, R A; smith, R M; Bock, R M (1951).
1573:Members of the National Academy of Medicine
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527:
292:Alberty is also known for his textbooks on
210:enzyme kinetics, biochemical thermodynamics
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131:
120:
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797:
756:
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314:Thermodynamics of Biochemical Reactions
109:Learn how and when to remove this message
655:Journal of the American Chemical Society
628:Journal of the American Chemical Society
563:Journal of the American Chemical Society
536:Journal of the American Chemical Society
506:Journal of the American Chemical Society
995:Eli Lilly Award in Biological Chemistry
404:. American Academy of Arts and Sciences
399:"Book of Members, 1780-2010: Chapter A"
390:
1558:University of Wisconsin–Madison alumni
621:
619:
364:and related compounds. He worked with
45:Please improve this article by adding
1553:University of Nebraska–Lincoln alumni
287:American Academy of Arts and Sciences
281:in 1947. For his work in the area of
264:Massachusetts Institute of Technology
7:
680:Alberty, R. A.; Bock, R. M. (1953).
436:The Journal of Physical Chemistry B
14:
23:
279:University of Wisconsin–Madison
201:University of Wisconsin–Madison
1:
918:10.1016/S0006-3495(97)78879-9
799:10.1016/S0021-9258(18)93127-3
758:10.1016/S0021-9258(19)52468-1
590:Biochimica et Biophysica Acta
47:secondary or tertiary sources
602:10.1016/0006-3002(54)90340-6
312:(2004). Other works include
268:National Academy of Sciences
262:, professor emeritus at the
258:(1921–2014) was an American
16:American chemist (1921–2014)
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1563:American physical chemists
349:enzyme-catalysed reactions
283:biochemical thermodynamics
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871:10.1016/j.bpc.2011.03.007
249:
222:
130:
953:Robert A. Alberty Papers
177:Cambridge, Massachusetts
959:Faculty web page at MIT
892:Alberty, R.A. (1997).
275:University of Nebraska
266:, and a member of the
197:University of Nebraska
34:relies excessively on
1198:Charles C. Richardson
859:Biophysical Chemistry
780:Alberty, R A (1969).
707:10.1073/pnas.39.9.895
351:, initially studying
256:Robert Arnold Alberty
234:Biophysical chemistry
125:Robert Arnold Alberty
1462:Christopher J. Chang
1438:Paul J. Hergenrother
1414:Benjamin Cravatt III
1312:Jacqueline K. Barton
1264:Christopher T. Walsh
1420:Dewey G. McCafferty
1348:Stuart L. Schreiber
1282:Harold M. Weintraub
1186:Phillips W. Robbins
910:1997BpJ....72.2349A
898:Biophysical Journal
835:10.1021/bi00158a025
829:(43): 10610–10615.
698:1953PNAS...39..895A
667:10.1021/ja00898a003
640:10.1021/ja01581a011
575:10.1021/ja01541a001
548:10.1021/ja01104a043
518:10.1021/ja01104a045
483:10.1021/j150457a018
442:(49): 16047–16050.
300:, co-authored with
260:biophysical chemist
58:"Robert A. Alberty"
1444:Scott K. Silverman
1426:Linda Hsieh-Wilson
1408:Andreas Matouschek
1366:Gregory L. Verdine
1330:George L. McLendon
1132:Harold A. Scheraga
1042:Earl A. Evans, Jr.
302:Farrington Daniels
298:Physical Chemistry
294:physical chemistry
1525:
1524:
1498:Bradley Pentelute
1468:Matthew D. Disney
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1258:Charles R. Cantor
1234:James E. Dahlberg
1204:Mario R. Capecchi
1180:Gerald M. Edelman
1168:William P. Jencks
1126:Robert A. Alberty
1120:William F. Neuman
1048:Herbert E. Carter
792:(12): 3290–3302.
661:(15): 2204–2209.
634:(24): 6379–6382.
448:10.1021/jp103554e
337:protein chemistry
310:Moungi G. Bawendi
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224:Scientific career
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1372:Alanna Schepartz
1336:Peter G. Schultz
1306:James E. Rothman
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1222:Bruce M. Alberts
1192:Gordon G. Hammes
1108:Nathan O. Kaplan
1096:John M. Buchanan
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1432:Anna K. Mapp
1378:John Kuriyan
1354:Peter S. Kim
1318:Peter Walter
1288:Richard Axel
1240:Mark Ptashne
1150:James Watson
1125:
1114:Harvey Itano
1030:Eric G. Ball
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171:(2014-01-18)
150:21 June 1921
105:
99:January 2023
96:
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53:
33:
1548:2014 deaths
1538:1921 births
1492:Howard Hang
1228:C. Fred Fox
1024:George Wald
316:(2003) and
185:Nationality
1532:Categories
1480:Minkui Luo
1174:Bruce Ames
385:References
345:mechanisms
146:1921-06-21
69:newspapers
36:references
1510:Yimon Aye
1144:Paul Berg
879:21501921
767:14907730
726:16589350
610:13140346
491:18918870
456:21141926
375:See also
353:fumarase
341:kinetics
327:Research
320:(2006).
188:American
154:Winfield
1474:Yi Tang
936:9129838
927:1184430
906:Bibcode
843:1420176
808:4307313
717:1063877
694:Bibcode
408:6 April
83:scholar
1518:(2021)
1512:(2020)
1506:(2019)
1500:(2018)
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