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Tooth resorption

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Interestingly, previous root trauma and unusual root morphology do not predispose one to OEIRR. Furthermore, endodontically treated teeth do not increase OIERR due to the absence of a vital pulp that can induce inflammation. Thus, it is recommended to take screening radiographs to detect for OIERR as indicated, use light forces especially for intrusive movements, and perform endodontic treatment if needed.
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However, due to the lack of robust evidence in treatment of other forms of external root resorption, there is currently no single recommended best treatment for the management of external root resorption. Treatments are case-dependent and dependent on clinical judgment and experience. Therefore, more
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External inflammatory root resorption may be caused by trauma to the root surface, due to damage to the periodontal ligament (PDL) and/or extended drying following tooth avulsion. Following trauma, dentinal tubules are exposed leading to communication with an infective or necrotic pulp. This leads to
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While resorption of bone is a normal physiological response to stimuli throughout the body, root resorption in permanent dentition and sometimes in the primary dentition is pathological. The root is protected internally (endodontium) by pre-dentin and externally on the root surface by cementum and
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It may also present as an incidental, radiographic finding. Radiographically, a radiolucent area of uniform density within the root canal may be visible with well-defined borders. Canal walls may appear sclerosed, thus the outline of pulp chambers or root canals may not be followed through the
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Chronic pulpal inflammation is thought to be a cause of internal resorption. The pulp must be vital below the area of resorption to provide osteoclasts with nutrients. If the pulp becomes totally necrosed the resorption will cease unless lateral canals are present to supply osteoclasts with
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can lead to RANKL release activating osteoclasts. Osteoclasts in close proximity to the root surface will resorb the root surface cementum and underlying root dentin. This can vary in severity from evidence of microscopic pits in the root surface to complete devastation of the root surface.
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Orthodontically induced external root resorption (OIERR) may occur during orthodontic treatment. The use of heavy, continuous force increases the incidence and severity of OIERR. Additionally,  forces directed toward the bone (i.e. intrusive) or lingual torque may also cause OEIRR.
395:.  When at least 3 teeth are affected, it is referred to as multiple idiopathic cervical root resorption. The causes of external cervical root resorption are poorly understood but trauma, periodontal treatment, and/or tooth whitening may be predisposing factors. 361:
Alternatively, pressure may also cause external inflammatory root resorption. Specifically, application of heavy, continuous, and intrusive (i.e. directed toward the bone) forces during  orthodontic tooth movement are associated with external root resorption.
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If the insult is transient, resorption will stop and healing will occur, this is known as transient inflammatory resorption. If the insult is persistent, then resorption continues, and if the tooth tissue is irretrievably damaged, complete resorption may occur.
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Choi BK, Moon SY, Cha JH, Kim KW, Yoo YJ (May 2005). "Prostaglandin E(2) is a main mediator in receptor activator of nuclear factor-kappaB ligand-dependent osteoclastogenesis induced by Porphyromonas gingivalis, Treponema denticola, and Treponema socranskii".
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External cervical resorption is a localised resorptive lesion in the cervical area of the tooth, below the epithelial attachment. It is distinguished from external inflammatory root resorption in that it rarely involves the
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Alhadainy, Hatem A.; Flores-Mir, Carlos; Abdel-Karim, Amany H.; Crossman, Jacqueline; El-Bialy, Tarek (May 2019). "Orthodontic-induced External Root Resorption of Endodontically Treated Teeth: A Meta-analysis".
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One thought is that the presence of bacteria plays a role. Bacterial presence leads to pulpal or peri-periapical inflammation. These bacteria are not mediators of osteoclast activity but do cause leukocyte
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When there is insult leading to inflammation (trauma, bacteria, tooth whitening, orthodontic movement, periodontal treatment) in the root canal/s or beside the external surface of the root,
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Andreasen JO (1981). "Relationship between cell damage in the periodontal ligament after replantation and subsequent development of root resorption. A time-related study in monkeys".
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Lossdörfer S, Götz W, Jäger A (July 2002). "Immunohistochemical localization of receptor activator of nuclear factor kappaB (RANK) and its ligand (RANKL) in human deciduous teeth".
329:(root canal therapy) may be carried out with the expectation of a fairly high success rate. Removing the stimulus (inflamed pulp) results in cessation of the resorptive process. 2579: 2761: 1808: 239:), also called osteoclast differentiation factor (ODF) and osteoprotegerin ligand (OPGL), is a regulator of osteoclast function. In physiological bone turn over, 2766: 374:. It is a transient, self-limiting process of resorption that ceases after removal of the traumatic stimulus and is followed by healing of root surface, 314:
Internal resorption is defined by the loss of intraradicular dentin and tubular dentin from within the middle and apical thirds of the root canal(s).
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External resorption is the loss of tooth structure from the external surface of the tooth and is further subcategorized based on its etiology.
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the periodontal ligament. Chronic stimuli that damage these protective layers expose underlying dentin to the action of osteoclasts.
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Osteoclasts are active during bone regulation, there is constant equilibrium between bone resorption and deposition. Damage to the
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Root resorption most commonly occurs due to inflammation caused by pulp necrosis, trauma, periodontal treatment,
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Resorptive lesions are categorized as internal or external and then further subdivided based on their etiology.
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Galler, Kerstin M.; Grätz, Eva-Maria; Widbiller, Matthias; Buchalla, Wolfgang; Knüttel, Helge (2021-03-26).
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External replacement root resorption (ERRR) occurs due to replacement of the root surface with bone, i.e.
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Weltman, Belinda; Vig, Katherine W.L.; Fields, Henry W.; Shanker, Shiva; Kaizar, Eloise E. (April 2010).
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are produced, the RANKL system is activated and osteoclasts are activated and resorb the root surface.
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Ahangari, Zohreh; Nasser, Mona; Mahdian, Mina; Fedorowicz, Zbys; Marchesan, Melissa A. (2015-11-24).
892: 780: 283: 267:. Leukocytes differentiate into osteoclasts in the presence of lipopolysaccharide antigens found in 3345: 3081: 3061: 3051: 2924: 2857: 2739: 2734: 2660: 2559: 2212: 2136: 1975: 1924: 1873: 1853: 1766: 1756: 1682: 1657: 1515: 602:"Pathophysiological mechanisms of root resorption after dental trauma: a systematic scoping review" 1622: 3388: 3242: 3046: 2862: 2810: 2771: 2468: 2384: 2315: 2024: 1848: 1828: 1781: 1667: 1612: 1575: 1565: 1550: 1480: 1287: 1215: 1143: 1002: 804: 753: 649: 326: 219: 187: 67: 3335: 3310: 2971: 879:
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki S, et al. (March 1998).
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species (these are all bacterial species associated with pulpal or periapical inflammation).
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The pathophysiology of root resorption is not completely understood. It is postulated that
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lesion. Lesions may also be oval radiolucencies that are continuous with the canal walls.
256: 206: 183: 163: 159: 158:. Root resorption is a normal physiological process that occurs in the exfoliation of the 419:. ERRR can be further categorized as transient or progressive depending on the extent of 896: 784: 771:
Boyle WJ, Simonet WS, Lacey DL (May 2003). "Osteoclast differentiation and activation".
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Proceedings of the National Academy of Sciences of the United States of America
618: 477:"Tooth resorption part I — pathogenesis and case series of internal resorption" 17: 3285: 3071: 2897: 2665: 2495: 2436: 2374: 2364: 2357: 2352: 2290: 2273: 2217: 2188: 2109: 1970: 1948: 1833: 1813: 1131: 1096: 1034: 989: 972: 264: 248: 240: 229: 225: 135: 82: 1330: 1275: 847: 741: 692: 627: 493: 3153: 3136: 2872: 2650: 2453: 2077: 1960: 1580: 1475: 1453: 1188: 1171: 822:
Patel, Shanon; Saberi, Navid; Pimental, Tiago; Teng, Peng-Hui (2022-03-30).
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If the condition is discovered before perforation of the root has occurred,
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Ne RF, Witherspoon DE, Gutmann JL (January 1999). "Tooth resorption".
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Occurs due to a localized and limited injury to the root surface or
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Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T (April 2012).
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Mak TW, Saunders ME (2006). "Cytokines and Cytokine Receptors".
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surface. Osteoclasts can break down bone, cartilage and dentin.
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damage with the latter resulting in complete root resorption.
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an inflammatory process that causes external root resorption.
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American Journal of Orthodontics and Dentofacial Orthopedics
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Trope M (2002). "Root resorption due to dental trauma".
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Breakdown of the tooth root to be absorbed by the blood
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Receptive activator of nuclear factor kappa-B ligand (
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are the cells responsible for the resorption of the
1367: 556:Fuss, Zvi; Tsesis, Igor; Lin, Shaul (August 2003). 125: 115: 105: 97: 89: 76: 66: 54: 35: 2842:Jaw joints, chewing muscles and bite abnormalities 475:Fernandes M, de Ataide I, Wagle R (January 2013). 72:Dark tooth discoloration, swollen gums, chip tooth 3197:Teeth, jaws, tongue and associated soft tissues 1809:Hereditary benign intraepithelial dyskeratosis 2767:Neuralgia-inducing cavitational osteonecrosis 1414: 8: 1209: 1207: 129:Dental crowns, tooth extraction, gum surgery 1311:The Cochrane Database of Systematic Reviews 1165: 1163: 1161: 1159: 1157: 3364: 3263: 3187: 2945: 2824: 2610: 2400: 2038: 1701: 1641: 1529: 1437: 1421: 1407: 1399: 1364: 551: 549: 50:Post traumatic External tooth resorption 9 41: 32: 1338: 1187: 988: 914: 904: 855: 731: 635: 617: 502: 492: 205: 166:and sometimes in the primary dentition. 3394:Oral manifestations of systemic disease 2543:Acute necrotizing ulcerative gingivitis 467: 2580:As a manifestation of systemic disease 456:Feline odontoclastic resorptive lesion 353:External Inflammatory Root Resorption 7: 2426:Gums and tooth-supporting structures 595: 593: 591: 399:External Replacement Root Resorption 3077:Papillary cystadenoma lymphomatosum 2920:Temporomandibular joint dysfunction 1170:Darcey J, Qualtrough A (May 2013). 973:"Regulation of osteoclast function" 714:Darcey, J.; Qualtrough, A. (2013). 255:which fuse and become osteoclasts. 2194:Maxillary lateral incisor agenesis 1678:Inflammatory papillary hyperplasia 685:10.1111/j.1365-2591.1985.tb00427.x 407:x-ray of external root resorption 25: 436:research is needed in this area. 386:External Cervical Root Resorption 3296:Cutaneous sinus of dental origin 3233:Obesity hypoventilation syndrome 3228:Central hypoventilation syndrome 3110:Carcinoma ex pleomorphic adenoma 2538:Necrotizing periodontal diseases 2518:Hereditary gingival fibromatosis 1430:Oral and maxillofacial pathology 1070:10.1034/j.1601-1546.2002.10106.x 948:10.1016/b978-012088451-3.50019-3 828:International Endodontic Journal 673:International Endodontic Journal 574:10.1034/j.1600-9657.2003.00192.x 366:External Surface Root Resorption 93:External (most common), internal 3142:Chronic sclerosing sialadenitis 2779:Osteoporotic bone marrow defect 2233:Keratocystic odontogenic tumour 3127:Sclerosing polycystic adenosis 2962:Benign lymphoepithelial lesion 1323:10.1002/14651858.CD008003.pub3 1120:Calcified Tissue International 1085:Acta Odontologica Scandinavica 1: 3321:Melkersson–Rosenthal syndrome 3270:Soft tissues around the mouth 2967:Ectopic salivary gland tissue 146:, is the progressive loss of 2491:Gingival cyst of the newborn 2100:Failure of eruption of teeth 1804:Hand, foot and mouth disease 1789:Focal epithelial hyperplasia 1727:Angina bullosa haemorrhagica 1673:Palatal cysts of the newborn 1596:Transient lingual papillitis 247:release RANKL, this acts on 3019:Salivary gland diverticulum 2982:Necrotizing sialometaplasia 1993:Smokeless tobacco keratosis 1905:Basaloid squamous carcinoma 1232:10.1016/j.ajodo.2009.06.021 3440: 3029:Salivary gland hyperplasia 2977:HIV salivary gland disease 2486:Gingival cyst of the adult 1932:Oral florid papillomatosis 1268:10.1016/j.joen.2019.02.001 619:10.1186/s12903-021-01510-6 217: 121:Dental examination, X-rays 3374: 3363: 3276: 3268:Orofacial soft tissues – 3262: 3203: 3186: 3034:Salivary gland hypoplasia 2957: 2944: 2848: 2823: 2762:Bisphosphonate-associated 2656:Idiopathic osteosclerosis 2631: 2609: 2432: 2399: 2127:Dentinogenesis imperfecta 2063: 2037: 1717: 1700: 1653: 1640: 1591:Median rhomboid glossitis 1541: 1528: 1449: 1436: 1132:10.1007/s00223-001-2086-7 1097:10.3109/00016358109162254 1035:10.1902/jop.2005.76.5.813 1023:Journal of Periodontology 990:10.3109/s10165-011-0530-8 667:Andreasen, J. O. (1985). 341:external root resorption 210:X-Ray of affected tooth ( 49: 40: 3424:Acquired tooth disorders 3341:Orofacial granulomatosis 3120:Mucoepidermoid carcinoma 3105:Adenoid cystic carcinoma 3039:Salivary gland neoplasms 2830:Temporomandibular joints 2801:Periapical periodontitis 2533:Linear gingival erythema 2301:Regional odontodysplasia 2147:Enamel hypocalcification 494:10.4103/0972-0707.105290 333:External root resorption 310:Internal root resorption 3238:Obstructive sleep apnea 3004:Salivary duct stricture 2784:Paget's disease of bone 2281:Pulp canal obliteration 2122:Dentin hypersensitivity 2068:Amelogenesis imperfecta 1920:Squamous cell carcinoma 1900:Adenosquamous carcinoma 1887:Squamous cell papilloma 1864:Melanocytic oral lesion 1189:10.1038/sj.bdj.2013.431 733:10.1038/sj.bdj.2013.431 427:Clinical considerations 3384:Hemifacial hypertrophy 3351:Pyostomatitis vegetans 3024:Salivary gland fistula 3014:Salivary gland atresia 3009:Salivary gland aplasia 2863:Mandibular dislocation 2834:muscles of mastication 2712:Calcifying odontogenic 2341:Vertical root fracture 2336:Cracked tooth syndrome 2311:Shovel-shaped incisors 2206:Wisdom tooth impaction 2088:Early childhood caries 1954:Benign mucous membrane 1915:Spindle cell carcinoma 1824:Intraoral dental sinus 1742:Burning mouth syndrome 1256:Journal of Endodontics 1176:British Dental Journal 906:10.1073/pnas.95.7.3597 720:British Dental Journal 412: 346: 215: 3193:Stomatognathic system 3095:Acinic cell carcinoma 2717:Glandular odontogenic 1869:Molluscum contagiosum 942:. Elsevier: 463–516. 406: 340: 209: 3336:Oral Crohn's disease 3291:Basal cell carcinoma 2930:Condylar hyperplasia 2915:Maxillary hypoplasia 2481:Gingival enlargement 2414:periodontal ligament 2020:Verruciform xanthoma 1752:Condyloma acuminatum 834:(Suppl 4): 892–921. 421:periodontal ligament 380:periodontal ligament 284:periodontal ligament 111:Trauma, orthodontics 3346:Perioral dermatitis 3082:Pleomorphic adenoma 3062:Monomorphic adenoma 3052:Canalicular adenoma 2925:Condylar hypoplasia 2858:Condylar resorption 2702:Lateral periodontal 2661:Mandibular fracture 2560:Periodontal abscess 2157:Turner's hypoplasia 1925:Verrucous carcinoma 1874:Morsicatio buccarum 1854:Lupus erythematosus 1767:Erythema multiforme 1683:Stomatitis nicotina 977:Modern Rheumatology 940:The Immune Response 897:1998PNAS...95.3597Y 793:10.1038/nature01658 785:2003Natur.423..337B 562:Dental Traumatology 182:tooth movement and 164:secondary dentition 138:of the root of the 3389:Facial hemiatrophy 3243:Periodic breathing 3174:Sjögren's syndrome 3047:Basal cell adenoma 2811:Torus mandibularis 2789:Periapical abscess 2772:Osteoradionecrosis 2697:Buccal bifurcation 2676:Intraosseous cysts 2565:Periodontal trauma 2469:Pyogenic granuloma 2316:Supernumerary root 2269:Pulp calcification 2257:Premature eruption 2228:Odontogenic tumors 2025:White sponge nevus 1998:Submucous fibrosis 1942:Smoker's melanosis 1829:Irritation fibroma 1668:High-arched palate 1576:Foliate papillitis 1566:Cunnilingus tongue 1551:Black hairy tongue 1481:Congenital lip pit 413: 347: 327:endodontic therapy 220:Calcium metabolism 216: 101:Trauma, idiopathic 3406: 3405: 3402: 3401: 3359: 3358: 3258: 3257: 3182: 3181: 3087:Sebaceous adenoma 2940: 2939: 2819: 2818: 2730:Median mandibular 2725:Nasopalatine duct 2641:Alveolar osteitis 2605: 2604: 2592:Perio-endo lesion 2474:Congenital epulis 2395: 2394: 2152:Enamel hypoplasia 2033: 2032: 2008:Riga–Fede disease 1859:Melanocytic nevus 1799:Hairy leukoplakia 1762:Epulis fissuratum 1696: 1695: 1636: 1635: 1586:Geographic tongue 1524: 1523: 1396: 1395: 1058:Endodontic Topics 957:978-0-12-088451-3 840:10.1111/iej.13715 160:primary dentition 154:by the action of 133: 132: 117:Diagnostic method 30:Medical condition 16:(Redirected from 3431: 3365: 3264: 3188: 3057:Ductal papilloma 2946: 2825: 2722:Non-odontogenic: 2707:Globulomaxillary 2646:Buccal exostosis 2611: 2555:Peri-implantitis 2401: 2117:Dentin dysplasia 2039: 2015:Verruca vulgaris 1910:Mucosal melanoma 1757:Darier's disease 1732:Behçet's disease 1702: 1658:Bednar's aphthae 1642: 1530: 1516:Trumpeter's wart 1438: 1423: 1416: 1409: 1400: 1365: 1353: 1352: 1342: 1317:(11): CD008003. 1302: 1296: 1295: 1250: 1244: 1243: 1211: 1202: 1201: 1191: 1167: 1152: 1151: 1115: 1109: 1108: 1080: 1074: 1073: 1053: 1047: 1046: 1017: 1011: 1010: 992: 968: 962: 961: 935: 929: 928: 918: 908: 876: 870: 869: 859: 819: 813: 812: 779:(6937): 337–42. 768: 762: 761: 735: 711: 705: 704: 664: 658: 657: 639: 621: 597: 586: 585: 553: 544: 543: 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708: 666: 665: 661: 606:BMC Oral Health 599: 598: 589: 555: 554: 547: 525: 524: 520: 474: 473: 469: 464: 451:Tooth ankylosis 446:Cementoblastoma 442: 429: 401: 388: 368: 355: 335: 312: 304: 302:Classifications 257:Osteoprotegerin 222: 204: 202:Pathophysiology 184:tooth whitening 172: 144:root resorption 36:Root resorption 31: 28: 23: 22: 18:Root resorption 15: 12: 11: 5: 3437: 3435: 3427: 3426: 3421: 3411: 3410: 3404: 3403: 3400: 3399: 3397: 3396: 3391: 3386: 3381: 3379:Eagle syndrome 3375: 3372: 3371: 3368: 3361: 3360: 3357: 3356: 3354: 3353: 3348: 3343: 3338: 3333: 3328: 3323: 3318: 3313: 3308: 3303: 3301:Cystic hygroma 3298: 3293: 3288: 3283: 3277: 3274: 3273: 3267: 3260: 3259: 3256: 3255: 3253: 3252: 3247: 3246: 3245: 3240: 3235: 3230: 3225: 3215: 3210: 3204: 3201: 3200: 3191: 3184: 3183: 3180: 3179: 3177: 3176: 3171: 3169:Sialolithiasis 3166: 3161: 3156: 3151: 3146: 3145: 3144: 3139: 3129: 3124: 3123: 3122: 3117: 3112: 3107: 3102: 3100:Adenocarcinoma 3097: 3089: 3084: 3079: 3074: 3069: 3067:Myoepithelioma 3064: 3059: 3054: 3049: 3036: 3031: 3026: 3021: 3016: 3011: 3006: 3001: 2996: 2995: 2994: 2984: 2979: 2974: 2969: 2964: 2958: 2955: 2954: 2949: 2942: 2941: 2938: 2937: 2935: 2934: 2933: 2932: 2927: 2917: 2912: 2911: 2910: 2905: 2900: 2895: 2890: 2885: 2880: 2875: 2865: 2860: 2855: 2849: 2846: 2845: 2828: 2821: 2820: 2817: 2816: 2814: 2813: 2808: 2803: 2798: 2797: 2796: 2786: 2781: 2776: 2775: 2774: 2769: 2764: 2754: 2749: 2744: 2743: 2742: 2740:Traumatic bone 2737: 2735:Median palatal 2732: 2727: 2719: 2714: 2709: 2704: 2699: 2694: 2689: 2673: 2668: 2663: 2658: 2653: 2648: 2643: 2638: 2632: 2629: 2628: 2614: 2607: 2606: 2603: 2602: 2600: 2599: 2594: 2589: 2588: 2587: 2582: 2577: 2567: 2562: 2557: 2552: 2547: 2546: 2545: 2535: 2530: 2528:Hypocementosis 2525: 2520: 2515: 2514: 2513: 2508: 2503: 2493: 2488: 2483: 2478: 2477: 2476: 2471: 2461: 2456: 2451: 2450: 2449: 2439: 2433: 2430: 2429: 2404: 2397: 2396: 2393: 2392: 2390: 2389: 2388: 2387: 2382: 2377: 2372: 2362: 2361: 2360: 2350: 2349: 2348: 2343: 2338: 2333: 2323: 2318: 2313: 2308: 2303: 2298: 2293: 2288: 2283: 2278: 2277: 2276: 2266: 2265: 2264: 2262:Neonatal teeth 2254: 2249: 2248: 2247: 2237: 2236: 2235: 2225: 2220: 2215: 2210: 2209: 2208: 2198: 2197: 2196: 2186: 2181: 2176: 2171: 2166: 2161: 2160: 2159: 2149: 2144: 2142:Ectopic enamel 2139: 2134: 2129: 2124: 2119: 2114: 2113: 2112: 2102: 2097: 2092: 2091: 2090: 2080: 2075: 2070: 2064: 2061: 2060: 2042: 2035: 2034: 2031: 2030: 2028: 2027: 2022: 2017: 2012: 2011: 2010: 2000: 1995: 1990: 1989: 1988: 1983: 1978: 1968: 1963: 1958: 1957: 1956: 1946: 1945: 1944: 1937:Oral melanosis 1934: 1929: 1928: 1927: 1922: 1917: 1912: 1907: 1902: 1894: 1889: 1876: 1871: 1866: 1861: 1856: 1851: 1846: 1841: 1836: 1831: 1826: 1821: 1816: 1811: 1806: 1801: 1796: 1791: 1786: 1785: 1784: 1774: 1769: 1764: 1759: 1754: 1749: 1744: 1739: 1737:Bohn's nodules 1734: 1729: 1724: 1722:Amalgam tattoo 1718: 1715: 1714: 1705: 1698: 1697: 1694: 1693: 1691: 1690: 1685: 1680: 1675: 1670: 1665: 1660: 1654: 1651: 1650: 1645: 1638: 1637: 1634: 1633: 1631: 1630: 1625: 1620: 1615: 1610: 1605: 1600: 1599: 1598: 1593: 1588: 1578: 1573: 1568: 1563: 1558: 1553: 1548: 1542: 1539: 1538: 1533: 1526: 1525: 1522: 1521: 1519: 1518: 1513: 1508: 1503: 1498: 1493: 1488: 1483: 1478: 1473: 1472: 1471: 1466: 1461: 1450: 1447: 1446: 1441: 1434: 1433: 1428: 1426: 1425: 1418: 1411: 1403: 1394: 1393: 1390: 1389: 1377: 1372: 1371: 1369: 1368:Classification 1361: 1360:External links 1358: 1355: 1354: 1297: 1245: 1226:(4): 462–476. 1203: 1153: 1110: 1075: 1048: 1012: 963: 956: 930: 871: 814: 763: 726:(9): 439–451. 706: 679:(2): 109–118. 659: 587: 568:(4): 175–182. 545: 518: 481:J Conserv Dent 466: 465: 463: 460: 459: 458: 453: 448: 441: 438: 428: 425: 400: 397: 387: 384: 367: 364: 354: 351: 334: 331: 311: 308: 303: 300: 203: 200: 171: 168: 131: 130: 127: 123: 122: 119: 113: 112: 109: 103: 102: 99: 95: 94: 91: 87: 86: 80: 74: 73: 70: 64: 63: 58: 52: 51: 47: 46: 38: 37: 29: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 3436: 3425: 3422: 3420: 3417: 3416: 3414: 3395: 3392: 3390: 3387: 3385: 3382: 3380: 3377: 3376: 3373: 3366: 3362: 3352: 3349: 3347: 3344: 3342: 3339: 3337: 3334: 3332: 3329: 3327: 3324: 3322: 3319: 3317: 3314: 3312: 3309: 3307: 3304: 3302: 3299: 3297: 3294: 3292: 3289: 3287: 3284: 3282: 3281:Actinomycosis 3279: 3278: 3275: 3271: 3265: 3261: 3251: 3248: 3244: 3241: 3239: 3236: 3234: 3231: 3229: 3226: 3224: 3221: 3220: 3219: 3216: 3214: 3211: 3209: 3206: 3205: 3202: 3198: 3194: 3189: 3185: 3175: 3172: 3170: 3167: 3165: 3162: 3160: 3159:Sialodochitis 3157: 3155: 3152: 3150: 3147: 3143: 3140: 3138: 3135: 3134: 3133: 3130: 3128: 3125: 3121: 3118: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3090: 3088: 3085: 3083: 3080: 3078: 3075: 3073: 3070: 3068: 3065: 3063: 3060: 3058: 3055: 3053: 3050: 3048: 3045: 3042: 3041: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3007: 3005: 3002: 3000: 2997: 2993: 2990: 2989: 2988: 2985: 2983: 2980: 2978: 2975: 2973: 2970: 2968: 2965: 2963: 2960: 2959: 2956: 2952: 2947: 2943: 2931: 2928: 2926: 2923: 2922: 2921: 2918: 2916: 2913: 2909: 2906: 2904: 2901: 2899: 2896: 2894: 2891: 2889: 2886: 2884: 2881: 2879: 2876: 2874: 2871: 2870: 2869: 2866: 2864: 2861: 2859: 2856: 2854: 2851: 2850: 2847: 2843: 2839: 2838:malocclusions 2835: 2831: 2826: 2822: 2812: 2809: 2807: 2806:Stafne defect 2804: 2802: 2799: 2795: 2792: 2791: 2790: 2787: 2785: 2782: 2780: 2777: 2773: 2770: 2768: 2765: 2763: 2760: 2759: 2758: 2757:Osteonecrosis 2755: 2753: 2752:Osteomyelitis 2750: 2748: 2745: 2741: 2738: 2736: 2733: 2731: 2728: 2726: 2723: 2720: 2718: 2715: 2713: 2710: 2708: 2705: 2703: 2700: 2698: 2695: 2693: 2690: 2688: 2685: 2683: 2679: 2678: 2677: 2674: 2672: 2669: 2667: 2664: 2662: 2659: 2657: 2654: 2652: 2649: 2647: 2644: 2642: 2639: 2637: 2634: 2633: 2630: 2626: 2625:Bones of jaws 2622: 2618: 2612: 2608: 2598: 2595: 2593: 2590: 2586: 2583: 2581: 2578: 2576: 2573: 2572: 2571: 2570:Periodontitis 2568: 2566: 2563: 2561: 2558: 2556: 2553: 2551: 2550:Pericoronitis 2548: 2544: 2541: 2540: 2539: 2536: 2534: 2531: 2529: 2526: 2524: 2521: 2519: 2516: 2512: 2509: 2507: 2506:Granulomatous 2504: 2502: 2499: 2498: 2497: 2494: 2492: 2489: 2487: 2484: 2482: 2479: 2475: 2472: 2470: 2467: 2466: 2465: 2462: 2460: 2459:Eruption cyst 2457: 2455: 2452: 2448: 2445: 2444: 2443: 2440: 2438: 2435: 2434: 2431: 2427: 2423: 2419: 2415: 2411: 2407: 2402: 2398: 2386: 2383: 2381: 2378: 2376: 2373: 2371: 2368: 2367: 2366: 2363: 2359: 2356: 2355: 2354: 2351: 2347: 2344: 2342: 2339: 2337: 2334: 2332: 2329: 2328: 2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2286:Pulp necrosis 2284: 2282: 2279: 2275: 2272: 2271: 2270: 2267: 2263: 2260: 2259: 2258: 2255: 2253: 2250: 2246: 2245:Dens in dente 2243: 2242: 2241: 2238: 2234: 2231: 2230: 2229: 2226: 2224: 2221: 2219: 2216: 2214: 2211: 2207: 2204: 2203: 2202: 2199: 2195: 2192: 2191: 2190: 2187: 2185: 2182: 2180: 2177: 2175: 2172: 2170: 2167: 2165: 2162: 2158: 2155: 2154: 2153: 2150: 2148: 2145: 2143: 2140: 2138: 2137:Discoloration 2135: 2133: 2130: 2128: 2125: 2123: 2120: 2118: 2115: 2111: 2108: 2107: 2106: 2103: 2101: 2098: 2096: 2093: 2089: 2086: 2085: 2084: 2081: 2079: 2076: 2074: 2071: 2069: 2066: 2065: 2062: 2057: 2053: 2049: 2045: 2040: 2036: 2026: 2023: 2021: 2018: 2016: 2013: 2009: 2006: 2005: 2004: 2001: 1999: 1996: 1994: 1991: 1987: 1984: 1982: 1979: 1977: 1974: 1973: 1972: 1969: 1967: 1964: 1962: 1959: 1955: 1952: 1951: 1950: 1947: 1943: 1940: 1939: 1938: 1935: 1933: 1930: 1926: 1923: 1921: 1918: 1916: 1913: 1911: 1908: 1906: 1903: 1901: 1898: 1895: 1893: 1890: 1888: 1885: 1882: 1881: 1880: 1877: 1875: 1872: 1870: 1867: 1865: 1862: 1860: 1857: 1855: 1852: 1850: 1847: 1845: 1844:Lichen planus 1842: 1840: 1837: 1835: 1832: 1830: 1827: 1825: 1822: 1820: 1819:Herpes zoster 1817: 1815: 1812: 1810: 1807: 1805: 1802: 1800: 1797: 1795: 1794:Fordyce spots 1792: 1790: 1787: 1783: 1780: 1779: 1778: 1775: 1773: 1772:Erythroplakia 1770: 1768: 1765: 1763: 1760: 1758: 1755: 1753: 1750: 1748: 1745: 1743: 1740: 1738: 1735: 1733: 1730: 1728: 1725: 1723: 1720: 1719: 1716: 1712: 1708: 1703: 1699: 1689: 1686: 1684: 1681: 1679: 1676: 1674: 1671: 1669: 1666: 1664: 1661: 1659: 1656: 1655: 1652: 1648: 1643: 1639: 1629: 1626: 1624: 1621: 1619: 1616: 1614: 1611: 1609: 1606: 1604: 1601: 1597: 1594: 1592: 1589: 1587: 1584: 1583: 1582: 1579: 1577: 1574: 1572: 1569: 1567: 1564: 1562: 1559: 1557: 1556:Caviar tongue 1554: 1552: 1549: 1547: 1546:Ankyloglossia 1544: 1543: 1540: 1536: 1531: 1527: 1517: 1514: 1512: 1511:Sun poisoning 1509: 1507: 1504: 1502: 1499: 1497: 1494: 1492: 1489: 1487: 1484: 1482: 1479: 1477: 1474: 1470: 1467: 1465: 1462: 1460: 1457: 1456: 1455: 1452: 1451: 1448: 1444: 1439: 1435: 1431: 1424: 1419: 1417: 1412: 1410: 1405: 1404: 1401: 1388: 1384: 1383: 1379: 1378: 1375: 1370: 1366: 1359: 1350: 1346: 1341: 1336: 1332: 1328: 1324: 1320: 1316: 1312: 1308: 1301: 1298: 1293: 1289: 1285: 1281: 1277: 1273: 1269: 1265: 1261: 1257: 1249: 1246: 1241: 1237: 1233: 1229: 1225: 1221: 1217: 1210: 1208: 1204: 1199: 1195: 1190: 1185: 1182:(9): 439–51. 1181: 1177: 1173: 1166: 1164: 1162: 1160: 1158: 1154: 1149: 1145: 1141: 1137: 1133: 1129: 1125: 1121: 1114: 1111: 1106: 1102: 1098: 1094: 1090: 1086: 1079: 1076: 1071: 1067: 1063: 1059: 1052: 1049: 1044: 1040: 1036: 1032: 1029:(5): 813–20. 1028: 1024: 1016: 1013: 1008: 1004: 1000: 996: 991: 986: 983:(2): 167–77. 982: 978: 974: 967: 964: 959: 953: 949: 945: 941: 934: 931: 926: 922: 917: 912: 907: 902: 898: 894: 890: 886: 882: 875: 872: 867: 863: 858: 853: 849: 845: 841: 837: 833: 829: 825: 818: 815: 810: 806: 802: 798: 794: 790: 786: 782: 778: 774: 767: 764: 759: 755: 751: 747: 743: 739: 734: 729: 725: 721: 717: 710: 707: 702: 698: 694: 690: 686: 682: 678: 674: 670: 663: 660: 655: 651: 647: 643: 638: 633: 629: 625: 620: 615: 611: 607: 603: 596: 594: 592: 588: 583: 579: 575: 571: 567: 563: 559: 552: 550: 546: 541: 537: 533: 529: 522: 519: 514: 510: 505: 500: 495: 490: 486: 482: 478: 471: 468: 461: 457: 454: 452: 449: 447: 444: 443: 439: 437: 433: 426: 424: 422: 418: 410: 405: 398: 396: 394: 385: 383: 381: 377: 373: 365: 363: 359: 352: 350: 344: 339: 332: 330: 328: 323: 319: 315: 309: 307: 301: 299: 295: 293: 288: 285: 280: 278: 274: 270: 269:Porphyromonas 266: 260: 258: 254: 250: 246: 245:stromal cells 242: 238: 233: 231: 227: 221: 213: 208: 201: 199: 197: 193: 189: 185: 181: 176: 169: 167: 165: 161: 157: 153: 149: 145: 141: 137: 128: 124: 120: 118: 114: 110: 108: 104: 100: 96: 92: 88: 84: 81: 79: 78:Complications 75: 71: 69: 65: 62: 59: 57: 53: 48: 44: 39: 34: 19: 3269: 3196: 3132:Sialadenitis 3091: 3043: 2908:Scissor bite 2903:Retrognathia 2888:Overeruption 2868:Malocclusion 2841: 2721: 2680: 2671:Micrognathia 2624: 2615:Periapical, 2501:Desquamative 2425: 2406:Periodontium 2380:Acid erosion 2321:Taurodontism 2305: 2252:Open contact 2164:Enamel pearl 2132:Dilaceration 2095:Concrescence 1896: 1883: 1710: 1663:Cleft palate 1623:Microglossia 1618:Macroglossia 1603:Glossoptosis 1501:Microcheilia 1496:Macrocheilia 1380: 1314: 1310: 1300: 1262:(5): 483–9. 1259: 1255: 1248: 1223: 1219: 1179: 1175: 1126:(1): 45–52. 1123: 1119: 1113: 1091:(1): 15–25. 1088: 1084: 1078: 1061: 1057: 1051: 1026: 1022: 1015: 980: 976: 966: 939: 933: 888: 884: 874: 831: 827: 817: 776: 772: 766: 723: 719: 709: 676: 672: 662: 609: 605: 565: 561: 531: 527: 521: 484: 480: 470: 434: 430: 414: 389: 372:periodontium 369: 360: 356: 348: 324: 320: 316: 313: 305: 296: 289: 281: 276: 272: 268: 261: 234: 223: 177: 173: 156:odontoclasts 143: 134: 107:Risk factors 3419:Endodontics 3326:Microstomia 3316:Macrostomia 3306:Gnathophyma 3223:Catathrenia 3218:Sleep apnea 3149:Sialectasis 2692:Dentigerous 2682:Odontogenic 2511:Plasma cell 2447:Gigantiform 2223:Microdontia 2213:Macrodontia 2184:Hyperdontia 1879:Oral cancer 1839:Leukoplakia 1747:Candidiasis 1707:Oral mucosa 1628:Rhabdomyoma 1608:Hypoglossia 1469:Plasma cell 534:(1): 9–25. 409:premolar 25 343:premolar 25 322:nutrients. 249:macrophages 241:osteoblasts 226:osteoclasts 180:orthodontic 85:, infection 3413:Categories 3286:Angioedema 3092:Malignant: 3072:Oncocytoma 2898:Prognathia 2687:periapical 2666:Microgenia 2617:mandibular 2575:Aggressive 2496:Gingivitis 2437:Cementicle 2375:Abfraction 2365:Tooth wear 2358:Edentulism 2353:Tooth loss 2306:Resorption 2291:Pulp polyp 2274:Pulp stone 2218:Meth mouth 2189:Hypodontia 2179:Gemination 2110:Talon cusp 2003:Ulceration 1971:Stomatitis 1949:Pemphigoid 1897:Malignant: 1849:Linea alba 1834:Leukoedema 1814:Herpangina 1782:Giant-cell 1064:: 79–100. 612:(1): 163. 487:(1): 4–8. 462:References 273:Prevotella 265:chemotaxis 218:See also: 136:Resorption 83:Tooth loss 3154:Sialocele 3137:Parotitis 2878:Open bite 2873:Crossbite 2651:Cherubism 2621:maxillary 2454:Cementoma 2385:Attrition 2201:Impaction 2169:Fluorosis 2078:Anodontia 2073:Ankylosis 1961:Pemphigus 1581:Glossitis 1476:Cleft lip 1454:Cheilitis 1331:1469-493X 1276:1878-3554 1007:218989802 848:0143-2885 742:0007-0610 693:0143-2885 654:232376543 628:1472-6831 417:ankylosis 292:cytokines 277:Treponema 253:monocytes 212:incisor 9 126:Treatment 61:Dentistry 56:Specialty 3164:Sialosis 3115:Lymphoma 2987:Mucocele 2883:Overbite 2636:Agnathia 2597:Teething 2422:alveolus 2418:cementum 2370:Abrasion 2346:Occlusal 2331:Avulsion 2296:Pulpitis 2240:Odontoma 1986:Herpetic 1976:Aphthous 1486:Eclabium 1349:26599212 1292:85500512 1284:30904319 1240:20362905 1198:23660900 1148:20902759 1140:12043011 1043:15898943 999:21953286 866:35229320 801:12748652 758:21870065 750:23660900 646:33771147 582:12848710 540:10323155 513:23349568 440:See also 376:cementum 214:, left). 152:cementum 68:Symptoms 3250:Snoring 3208:Bruxism 3044:Benign: 2893:Overjet 2853:Bruxism 2747:Osteoma 2585:Chronic 2410:gingiva 1884:Benign: 1777:Fibroma 1464:Angular 1459:Actinic 1387:D014091 1340:7185846 1105:6943905 925:9520411 893:Bibcode 857:9790676 809:4428121 781:Bibcode 701:2860072 637:7995728 504:3548344 190:teeth, 188:ectopic 2992:Ranula 2464:Epulis 2326:Trauma 2174:Fusion 2083:Caries 2056:enamel 2052:dentin 1647:Palate 1535:Tongue 1347:  1337:  1329:  1290:  1282:  1274:  1238:  1196:  1146:  1138:  1103:  1041:  1005:  997:  954:  923:  913:  864:  854:  846:  807:  799:  773:Nature 756:  748:  740:  699:  691:  652:  644:  634:  626:  580:  538:  511:  501:  378:, and 196:tumors 194:, and 170:Causes 148:dentin 98:Causes 3369:Other 2044:Teeth 1288:S2CID 1144:S2CID 1003:S2CID 916:19881 805:S2CID 754:S2CID 650:S2CID 237:RANKL 192:cysts 142:, or 140:tooth 90:Types 3331:Noma 2836:and 2619:and 2424:) – 2048:pulp 1443:Lips 1382:MeSH 1345:PMID 1327:ISSN 1315:2016 1280:PMID 1272:ISSN 1236:PMID 1194:PMID 1136:PMID 1101:PMID 1039:PMID 995:PMID 952:ISBN 921:PMID 862:PMID 844:ISSN 797:PMID 746:PMID 738:ISSN 697:PMID 689:ISSN 642:PMID 624:ISSN 578:PMID 536:PMID 509:PMID 393:pulp 275:and 251:and 243:and 230:root 150:and 1335:PMC 1319:doi 1264:doi 1228:doi 1224:137 1184:doi 1180:214 1128:doi 1093:doi 1066:doi 1031:doi 985:doi 944:doi 911:PMC 901:doi 852:PMC 836:doi 789:doi 777:423 728:doi 724:214 681:doi 632:PMC 614:doi 570:doi 499:PMC 489:doi 3415:: 3195:– 2840:– 2832:, 2420:, 2416:, 2412:, 2054:, 2050:, 1709:– 1385:: 1343:. 1333:. 1325:. 1313:. 1309:. 1286:. 1278:. 1270:. 1260:45 1258:. 1234:. 1222:. 1218:. 1206:^ 1192:. 1178:. 1174:. 1156:^ 1142:. 1134:. 1124:71 1122:. 1099:. 1089:39 1087:. 1060:. 1037:. 1027:76 1025:. 1001:. 993:. 981:22 979:. 975:. 950:. 919:. 909:. 899:. 889:95 887:. 883:. 860:. 850:. 842:. 832:55 830:. 826:. 803:. 795:. 787:. 775:. 752:. 744:. 736:. 722:. 718:. 695:. 687:. 677:18 675:. 671:. 648:. 640:. 630:. 622:. 610:21 608:. 604:. 590:^ 576:. 566:19 564:. 560:. 548:^ 532:30 530:. 507:. 497:. 485:16 483:. 479:. 382:. 271:, 198:. 2684:: 2408:( 2058:) 2046:( 1422:e 1415:t 1408:v 1374:D 1351:. 1321:: 1294:. 1266:: 1242:. 1230:: 1200:. 1186:: 1150:. 1130:: 1107:. 1095:: 1072:. 1068:: 1062:1 1045:. 1033:: 1009:. 987:: 960:. 946:: 927:. 903:: 895:: 868:. 838:: 811:. 791:: 783:: 760:. 730:: 703:. 683:: 656:. 616:: 584:. 572:: 542:. 515:. 491:: 411:. 345:. 20:)

Index

Root resorption

Specialty
Dentistry
Symptoms
Complications
Tooth loss
Risk factors
Diagnostic method
Resorption
tooth
dentin
cementum
odontoclasts
primary dentition
secondary dentition
orthodontic
tooth whitening
ectopic
cysts
tumors

incisor 9
Calcium metabolism
osteoclasts
root
RANKL
osteoblasts
stromal cells
macrophages

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