206:
In July 2014, the Broad
Institute announced that Ted Stanley had committed an additional $ 650 million to the center. The commitment – the largest ever made for psychiatric research—was aimed at "enhancing scientific research on psychiatric disorders with the hopes of leading to a breakthrough in
430:
The
Stanley Center for Psychiatric Research is based at 75 Ames Street in Cambridge, Massachusetts. The building at 75 Ames Street opened in May 2014 and became the workplace of 800 Broad researchers. The building was named "The Ted and Vada Stanley Building" in September 2014.
620:
172:
Within a year of its inception, researchers at the center and their international collaborators published a paper on their analysis of a collection of more than 7,000 genetic samples for
886:
443:
The
Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.
876:
230:
The Center consists of more than 150 scientists from the Broad
Institute and the Broad's partner institutions (MIT, Harvard, and Harvard-affiliated hospitals). These include:
302:
728:
881:
165:
The
Stanley Center for Psychiatric Research at Broad Institute was launched in 2007 with Edward Scolnick, M.D., former head of research and development at
523:
242:
185:
291:
285:
247:
111:
234:
603:
450:
Schizophrenia
Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci.
196:
307:
258:
211:
123:
650:
263:
127:
210:
The announcement coincided with the publication of a paper by
Stanley Center researchers and collaborators, as part of the
253:
119:
281:
Researchers at the
Stanley Center also collaborate with investigators in various consortia and institutions, including:
166:
663:
569:
586:
148:
98:
238:
40:
792:
834:
813:
758:
638:$ 650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research.
275:
540:
296:
176:. The center later launched efforts to collect and sequence genetic samples for such conditions as
71:
742:
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
191:
In early 2012, Scolnick stepped down as director and became the
Stanley Center's chief scientist.
200:
115:
775:
741:
439:
Publications authored by researchers from the
Stanley Center for Psychiatric Research include:
278:, neurobiology, stem cell biology, biochemistry, medicinal chemistry, and clinical psychiatry.
177:
703:
268:
181:
144:
365:
56:
36:
870:
457:
McCarroll SA, Feng G, Hyman SE. Genome-scale neurogenetics: Methodology and meaning.
274:
Affiliated researchers come from multiple fields and disciplines including genetics,
219:
173:
700:
559:. Stanley Center for Psychiatric Research at Broad Institute. Retrieved 2015-02-04.
375:
331:
327:
318:
The current leadership of the Stanley Center for Psychiatric Research consists of:
215:
192:
80:
76:
857:
Official website of the Stanley Center for Psychiatric Research at Broad Institute
740:
The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium.
513:. Stanley Center for Psychiatric Research at Broad Institute. Retrieved 2015-02-04
90:
The Ted and Vada Stanley Building, 75 Ames Street, Cambridge, Massachusetts 02142
385:
155:
60:
556:
510:
106:
64:
637:
541:
Rare chromosomal deletions and duplications increase risk of schizophrenia
475:. A polygenic burden of rare disruptive mutations in schizophrenia. 2014.
151:, Massachusetts that studies the biological basis of psychiatric disease.
52:
856:
757:
Schizophrenia Working Group of the Psychiatric Genomics Consortium.
547:
advance online publication. July 30, 2008. DOI: 10.1038/nature07239.
759:
Biological insights from 108 schizophrenia-associated genetic loci
861:
154:
The center was founded in 2007 with funding from philanthropists
131:
814:
A polygenic burden of rare disruptive mutations in schizophrenia
147:
is a multi-disciplinary biomedical research program located in
604:
Mental wellness warriors: Fighting for those who need it most.
490:
mutations in schizophrenia implicate synaptic networks. 2014.
621:
Broad Institute receives $ 650 million mental research gift.
222:
through the genetic analysis of 110,000 cases and controls.
16:
Biomedical research program in Cambridge, Massachusetts, USA
20:
Stanley Center for Psychiatric Research at Broad Institute
765:. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595.
664:
Fact Sheet: The Stanley Center for Psychiatric Research.
524:
How a Giant Act of Philanthropy May Kickstart Psychiatry
454:. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595.
838:
mutations in schizophrenia implicate synaptic networks.
729:
Broad Institute moves 800 researchers to new building.
464:
Hyman, SE. Perspective: Revealing molecular secrets.
776:
Genome-scale neurogenetics: Methodology and meaning
105:
94:
86:
70:
46:
32:
24:
799:. 2014 Apr 3;508(7494):S20. doi: 10.1038/508S20a.
468:. 2014 Apr 3;508(7494):S20. doi: 10.1038/508S20a.
887:Organizations based in Cambridge, Massachusetts
303:University of North Carolina School of Medicine
235:Harvard University Faculty of Arts and Sciences
782:. 2014 Jun;17(6):756-63. doi: 10.1038/nn.3716.
748:. Online 19 January 2015. DOI: 10.1038/nn.3922
461:. 2014 Jun;17(6):756-63. doi: 10.1038/nn.3716.
447:. Online 19 January 2015. DOI: 10.1038/nn.3922
8:
539:The International Schizophrenia Consortium.
19:
877:Research organizations in the United States
723:Dayal McCluskey, Priyanka. (May 21, 2014).
557:http://www.broadinstitute.org/psych/stanley
511:http://www.broadinstitute.org/psych/stanley
214:, that identified over 100 regions in the
18:
243:Harvard T.H. Chan School of Public Health
844:. 2014 Jan 22. doi: 10.1038/nature12929.
820:. 2014 Jan 22. doi: 10.1038/nature12975.
793:Perspective: Revealing molecular secrets
666:" Broad Institute. Retrieved 2015-02-04.
653:" Broad Institute. Retrieved 2015-02-04.
494:. 2014 Jan 22. doi: 10.1038/nature12929.
479:. 2014 Jan 22. doi: 10.1038/nature12975.
372:Director, Model Systems and Neurobiology
186:attention deficit hyperactivity disorder
862:Official website of the Broad Institute
503:
292:Icahn School of Medicine at Mount Sinai
141:Stanley Center for Psychiatric Research
188:(ADHD), in addition to schizophrenia.
882:Multidisciplinary research institutes
286:Cardiff University School of Medicine
248:Massachusetts Institute of Technology
112:Massachusetts Institute of Technology
7:
570:Hyman to lead Broad research center.
392:Director, Translational Neurobiology
203:, was named director of the center.
651:Partner Institutions and Community.
197:National Institute of Mental Health
585:Zimmer, Carl and Benedict Carey. "
416:Director, Viral Vector Engineering
145:Broad Institute of MIT and Harvard
14:
640:" Broad Institute. July 22, 2014.
308:University of Southern California
774:McCarroll SA, Feng G, Hyman SE.
400:Director, Translational Research
212:Psychiatric Genomics Consortium
195:, M.D., former director of the
264:Massachusetts General Hospital
128:Massachusetts General Hospital
1:
408:Director, Medicinal Chemistry
362:Director, Population Genetics
587:Spark for a Stagnant Search.
259:Brigham and Women's Hospital
169:, as its founding director.
124:Brigham and Women's Hospital
701:"Morgan Sheng, M.D., Ph.D."
382:Director, Stem Cell Biology
167:Merck Research Laboratories
903:
254:Boston Children's Hospital
120:Boston Children's Hospital
338:Chief Scientist Emeritus
226:Organizational structure
346:Administrative Director
239:Harvard Medical School
199:and former provost of
48:Field of research
41:translational research
276:computational biology
184:disorders (ASDs) and
156:Ted and Vada Stanley.
576:. February 15, 2012.
297:Karolinska Institute
65:Psychiatric medicine
746:Nature Neuroscience
619:Johnson, Carolyn. "
610:. January 17, 2015.
445:Nature Neuroscience
39:(non-clinical) and
21:
522:Herper, Matthew. "
354:Director, Genetics
201:Harvard University
116:Harvard University
33:Research type
423:
422:
357:Steven McCarroll
207:new treatments."
137:
136:
894:
845:
827:
821:
806:
800:
789:
783:
772:
766:
755:
749:
738:
732:
721:
715:
714:
712:
710:
697:
691:
685:
679:
673:
667:
660:
654:
647:
641:
634:
628:
627:. July 22, 2014.
617:
611:
600:
594:
593:. July 21, 2014.
583:
577:
566:
560:
554:
548:
537:
531:
530:. July 22, 2014.
520:
514:
508:
411:Florence Wagner
341:Edward Scolnick
321:
320:
218:associated with
178:bipolar disorder
22:
902:
901:
897:
896:
895:
893:
892:
891:
867:
866:
853:
848:
828:
824:
807:
803:
790:
786:
773:
769:
756:
752:
739:
735:
722:
718:
708:
706:
704:Broad Institute
699:
698:
694:
686:
682:
674:
670:
661:
657:
648:
644:
635:
631:
618:
614:
602:Drash, Wayne. "
601:
597:
584:
580:
574:Harvard Gazette
567:
563:
555:
551:
538:
534:
521:
517:
509:
505:
501:
437:
428:
316:
269:McLean Hospital
228:
182:autism spectrum
163:
132:McLean Hospital
130:
126:
122:
118:
114:
101:, Massachusetts
49:
17:
12:
11:
5:
900:
898:
890:
889:
884:
879:
869:
868:
865:
864:
859:
852:
851:External links
849:
847:
846:
822:
801:
784:
767:
750:
733:
716:
692:
680:
668:
655:
642:
629:
612:
595:
591:New York Times
578:
561:
549:
532:
515:
502:
500:
497:
496:
495:
480:
469:
462:
455:
448:
436:
433:
427:
424:
421:
420:
417:
413:
412:
409:
405:
404:
403:Jeff Cottrell
401:
397:
396:
393:
389:
388:
383:
379:
378:
373:
369:
368:
366:Benjamin Neale
363:
359:
358:
355:
351:
350:
347:
343:
342:
339:
335:
334:
325:
315:
312:
311:
310:
305:
300:
294:
289:
272:
271:
266:
261:
256:
251:
245:
227:
224:
162:
159:
135:
134:
109:
103:
102:
96:
92:
91:
88:
84:
83:
74:
68:
67:
57:Bioinformatics
50:
47:
44:
43:
34:
30:
29:
26:
15:
13:
10:
9:
6:
4:
3:
2:
899:
888:
885:
883:
880:
878:
875:
874:
872:
863:
860:
858:
855:
854:
850:
843:
839:
837:
832:
826:
823:
819:
815:
811:
805:
802:
798:
794:
788:
785:
781:
777:
771:
768:
764:
760:
754:
751:
747:
743:
737:
734:
730:
726:
720:
717:
705:
702:
696:
693:
689:
684:
681:
677:
672:
669:
665:
659:
656:
652:
646:
643:
639:
633:
630:
626:
622:
616:
613:
609:
605:
599:
596:
592:
588:
582:
579:
575:
571:
568:Colen, B.D. "
565:
562:
558:
553:
550:
546:
542:
536:
533:
529:
525:
519:
516:
512:
507:
504:
498:
493:
489:
485:
481:
478:
474:
470:
467:
463:
460:
456:
453:
449:
446:
442:
441:
440:
434:
432:
425:
419:Ben Deverman
418:
415:
414:
410:
407:
406:
402:
399:
398:
394:
391:
390:
387:
384:
381:
380:
377:
374:
371:
370:
367:
364:
361:
360:
356:
353:
352:
349:Lynn Harwell
348:
345:
344:
340:
337:
336:
333:
329:
326:
323:
322:
319:
313:
309:
306:
304:
301:
298:
295:
293:
290:
287:
284:
283:
282:
279:
277:
270:
267:
265:
262:
260:
257:
255:
252:
249:
246:
244:
240:
236:
233:
232:
231:
225:
223:
221:
220:schizophrenia
217:
213:
208:
204:
202:
198:
194:
189:
187:
183:
179:
175:
174:schizophrenia
170:
168:
160:
158:
157:
152:
150:
146:
142:
133:
129:
125:
121:
117:
113:
110:
108:
104:
100:
97:
93:
89:
85:
82:
78:
75:
73:
69:
66:
62:
58:
54:
51:
45:
42:
38:
35:
31:
27:
23:
841:
835:
830:
825:
817:
809:
804:
796:
787:
780:Nat Neurosci
779:
770:
762:
753:
745:
736:
725:Boston Globe
724:
719:
707:. Retrieved
695:
687:
683:
675:
671:
658:
645:
632:
625:Boston Globe
624:
615:
607:
598:
590:
581:
573:
564:
552:
544:
535:
527:
518:
506:
491:
487:
483:
476:
472:
465:
459:Nat Neurosci
458:
451:
444:
438:
429:
376:Guoping Feng
332:Morgan Sheng
328:Steven Hyman
317:
280:
273:
229:
216:human genome
209:
205:
193:Steven Hyman
190:
171:
164:
153:
140:
138:
107:Affiliations
81:Morgan Sheng
77:Steven Hyman
808:Purcell SM
791:Hyman, SE.
471:Purcell SM
386:Kevin Eggan
61:Biomedicine
25:Established
871:Categories
709:1 November
499:References
426:Facilities
314:Leadership
829:Fromer M
482:Fromer M
324:Directors
149:Cambridge
99:Cambridge
816:. 2014.
435:Research
395:Jen Pan
299:, Sweden
95:Location
72:Director
53:Genomics
836:De novo
488:De novo
161:History
87:Address
842:Nature
840:2014.
818:Nature
797:Nature
763:Nature
545:Nature
528:Forbes
492:Nature
477:Nature
466:Nature
452:Nature
241:; and
831:et al
810:et al
484:et al
473:et al
250:(MIT)
37:Basic
711:2023
688:Ibid
676:Ibid
288:, UK
139:The
28:2007
727:. "
608:CNN
526:."
143:at
873::
833:.
812:.
795:.
778:.
761:.
744:.
623:"
606:"
589:"
572:"
543:.
486:.
330:,
237:;
180:,
79:,
63:,
59:,
55:,
731:"
713:.
690:.
678:.
662:"
649:"
636:"
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.