252:
229:
126:
151:
258:
157:
1848:
1794:
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T,
1154:
have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated,
1684:
Runte M, Hüttenhofer A, Gross S, Kiefmann M, Horsthemke B, Buiting K (November 2001). "The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A".
1714:
Runte M, Kroisel PM, Gillessen-Kaesbach G, Varon R, Horn D, Cohen MY, Wagstaff J, Horsthemke B, Buiting K (May 2004). "SNURF-SNRPN and UBE3A transcript levels in patients with
Angelman syndrome".
1507:
Esposito F, Fiore F, Cimino F, Russo T (August 1993). "Isolation and structural characterization of the rat gene encoding the brain specific snRNP-associated polypeptide "N"".
1431:"Expression of the major human ribonucleoprotein (RNP) autoantigens in Escherichia coli and their use in an EIA for screening sera from patients with autoimmune diseases"
265:
164:
1143:
737:
87:
718:
1797:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
1889:
1908:
1252:
1234:
1616:"Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms"
1466:"Isolation of cDNA clones encoding the human Sm B/B' auto-immune antigen and specifically reacting with human anti-Sm auto-immune sera"
251:
1053:
1060:
228:
1332:
1221:
1200:
150:
125:
1217:
1651:"Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein"
1196:
264:
163:
1882:
257:
156:
1160:
1151:
782:
75:
763:
1913:
1875:
1172:
139:
1396:"Primary structure of a human small nuclear ribonucleoprotein polypeptide as deduced by cDNA analysis"
1477:
1283:
62:
1164:
1015:
1011:
1007:
1003:
999:
995:
991:
987:
983:
979:
975:
971:
967:
963:
959:
955:
951:
947:
943:
939:
864:
1134:
This gene encodes a highly basic protein localized to the nucleus. The evolutionarily constrained
1739:
1649:
Saville B, Poukka H, Wormke M, Janne OA, Palvimo JJ, Stoner M, Samudio I, Safe S (January 2002).
1139:
1135:
99:
1036:
935:
931:
921:
917:
913:
909:
905:
885:
860:
856:
1826:
1782:
1731:
1702:
1672:
1637:
1602:
1559:
1536:
Glenn CC, Saitoh S, Jong MT, Filbrandt MM, Surti U, Driscoll DJ, Nicholls RD (February 1996).
1524:
1495:
1452:
1417:
1382:
1311:
1168:
55:
1859:
1753:"Characterization of cis- and trans-acting elements in the imprinted human SNURF-SNRPN locus"
1816:
1808:
1772:
1764:
1723:
1694:
1662:
1627:
1592:
1584:
1549:
1516:
1485:
1442:
1407:
1372:
1364:
1301:
1291:
344:
275:
219:
174:
95:
319:
1573:"Breakage in the SNRPN locus in a balanced 46,XY,t(15;19) Prader-Willi syndrome patient"
1481:
1287:
1821:
1796:
1777:
1752:
1597:
1572:
1554:
1537:
1175:
due to parental imprint switch failure. The function of this protein is not yet known.
1150:
of the transcript, a region that has been identified as an imprinting center. Multiple
1412:
1395:
1377:
1352:
652:
647:
642:
637:
621:
616:
611:
606:
601:
596:
591:
586:
581:
576:
571:
566:
561:
545:
540:
535:
1902:
1490:
1465:
1306:
1271:
1156:
522:
1743:
79:
1538:"Gene structure, DNA methylation, and imprinted expression of the human SNRPN gene"
337:
116:
31:
1447:
1430:
1353:"A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'"
1272:"An imprinted, mammalian bicistronic transcript encodes two independent proteins"
103:
1257:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1239:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1429:
Renz M, Heim C, Bräunling O, Czichos A, Wieland C, Seelig HP (September 1989).
1276:
Proceedings of the
National Academy of Sciences of the United States of America
420:
1727:
1571:
Sun Y, Nicholls RD, Butler MG, Saitoh S, Hainline BE, Palmer CG (April 1996).
236:
133:
83:
1698:
1368:
1296:
682:
480:
358:
303:
290:
202:
189:
91:
1830:
1786:
1735:
1706:
1676:
1667:
1650:
1641:
1520:
1351:
Schmauss C, McAllister G, Ohosone Y, Hardin JA, Lerner MR (February 1989).
1315:
1632:
1615:
1606:
1588:
1563:
1528:
1499:
1456:
1421:
1386:
1100:
1095:
1768:
1084:
831:
812:
808:
1855:
1812:
1116:
794:
749:
1847:
1614:
Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ (January 2000).
1464:
Sharpe NG, Williams DG, Howarth DN, Coles B, Latchman DS (July 1989).
1068:
704:
17:
667:
663:
66:, SNRPN upstream reading frame, SNRPN upstream open reading frame
1795:
Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006).
1147:
1123:
1394:
Rokeach LA, Jannatipour M, Haselby JA, Hoch SO (March 1989).
1751:
Rodriguez-Jato S, Nicholls RD, Driscoll DJ, Yang TP (2005).
1159:
transcript. Alternative splicing or deletion caused by a
327:
1863:
1146:. The upstream coding region utilizes the first three
492:
1509:
1142:transcript which has a downstream ORF encoding the
1029:
904:
878:
849:
439:
dentate gyrus of hippocampal formation granule cell
1213:
1211:
1209:
1192:
1190:
1188:
30:"snurf" redirects here. For the winter sport, see
1333:"Entrez Gene: SNURF SNRPN upstream reading frame"
274:
173:
27:Protein-coding gene in the species Homo sapiens
1218:GRCm38: Ensembl release 89: ENSMUSG00000102627
1883:
1144:small nuclear ribonucleoprotein polypeptide N
8:
1270:Gray TA, Saitoh S, Nicholls RD (May 1999).
1197:GRCh38: Ensembl release 89: ENSG00000273173
1890:
1876:
901:
678:
518:
315:
214:
111:
1820:
1776:
1666:
1631:
1596:
1553:
1489:
1446:
1411:
1376:
1305:
1295:
1327:
1325:
1184:
1167:or coding region of this gene leads to
602:small nuclear ribonucleoprotein complex
36:
279:
240:
235:
178:
137:
132:
7:
1844:
1842:
1113:SNRPN upstream reading frame protein
1655:The Journal of Biological Chemistry
1620:The Journal of Biological Chemistry
1400:The Journal of Biological Chemistry
1862:. You can help Knowledge (XXG) by
1542:American Journal of Human Genetics
1026:
875:
846:
822:
799:
773:
754:
728:
709:
497:
415:
353:
332:
25:
1119:that in humans is encoded by the
1846:
263:
256:
250:
227:
162:
155:
149:
124:
1152:transcription initiation sites
648:mRNA splicing, via spliceosome
481:More reference expression data
1:
1413:10.1016/S0021-9258(18)83693-6
248:
147:
1909:Genes on human chromosome 15
1491:10.1016/0014-5793(89)80801-4
587:U4/U6 x U5 tri-snRNP complex
582:catalytic step 2 spliceosome
373:stromal cell of endometrium
1930:
1841:
1448:10.1093/clinchem/35.9.1861
29:
1728:10.1007/s00439-004-1104-z
1253:"Mouse PubMed Reference:"
1235:"Human PubMed Reference:"
1099:
1094:
1090:
1083:
1067:
1048:
1033:
928:
897:
882:
853:
842:
829:
825:
806:
802:
793:
780:
776:
761:
757:
748:
735:
731:
716:
712:
703:
688:
681:
677:
661:
521:
517:
505:
500:
491:
478:
427:
418:
401:Descending thoracic aorta
365:
356:
326:
318:
314:
297:
284:
247:
226:
217:
213:
196:
183:
146:
123:
114:
110:
73:
70:
60:
53:
48:
44:
39:
1687:Human Molecular Genetics
1577:Human Molecular Genetics
1054:Chr 15: 24.95 – 24.98 Mb
1297:10.1073/pnas.96.10.5616
1061:Chr 7: 59.65 – 59.65 Mb
1858:-related article is a
1757:Nucleic Acids Research
1699:10.1093/hmg/10.23.2687
1668:10.1074/jbc.M109021200
1521:10.1006/bbrc.1993.2047
1357:Nucleic Acids Research
607:U2-type prespliceosome
463:Cortex of frontal lobe
451:neural layer of retina
385:superior frontal gyrus
381:skeletal muscle tissue
1633:10.1074/jbc.275.1.571
1369:10.1093/nar/17.4.1733
1173:Prader-Willi syndrome
443:primary visual cortex
140:Chromosome 15 (human)
592:spliceosomal complex
435:striatum of neuraxis
242:Chromosome 7 (mouse)
1589:10.1093/hmg/5.4.517
1482:1989FEBSL.250..585S
1288:1999PNAS...96.5616G
1165:untranslated region
653:response to hormone
377:islet of Langerhans
369:ganglionic eminence
1813:10.1101/gr.4039406
1769:10.1093/nar/gki786
1435:Clinical Chemistry
1136:open reading frame
783:ENSMUSG00000102627
638:biological process
631:Biological process
555:Cellular component
536:molecular function
529:Molecular function
1871:
1870:
1169:Angelman syndrome
1110:
1109:
1106:
1105:
1079:
1078:
1044:
1043:
1023:
1022:
893:
892:
872:
871:
838:
837:
819:
818:
789:
788:
770:
769:
744:
743:
725:
724:
673:
672:
513:
512:
509:
508:
487:
486:
474:
473:
459:cerebellar cortex
412:
411:
310:
309:
209:
208:
104:SNURF - orthologs
16:(Redirected from
1921:
1892:
1885:
1878:
1850:
1843:
1834:
1824:
1790:
1780:
1747:
1710:
1693:(23): 2687–700.
1680:
1670:
1645:
1635:
1610:
1600:
1567:
1557:
1532:
1503:
1493:
1460:
1450:
1425:
1415:
1390:
1380:
1337:
1336:
1329:
1320:
1319:
1309:
1299:
1267:
1261:
1260:
1249:
1243:
1242:
1231:
1225:
1215:
1204:
1194:
1163:event in the 5'
1092:
1091:
1063:
1056:
1039:
1027:
1018:
902:
898:RefSeq (protein)
888:
876:
867:
847:
823:
800:
774:
755:
729:
710:
679:
519:
498:
483:
423:
421:Top expressed in
416:
361:
359:Top expressed in
354:
333:
316:
306:
293:
282:
267:
260:
254:
243:
231:
215:
205:
192:
181:
166:
159:
153:
142:
128:
112:
106:
65:
58:
37:
21:
1929:
1928:
1924:
1923:
1922:
1920:
1919:
1918:
1899:
1898:
1897:
1896:
1839:
1837:
1801:Genome Research
1793:
1763:(15): 4740–53.
1750:
1713:
1683:
1648:
1613:
1570:
1535:
1506:
1463:
1428:
1393:
1350:
1346:
1344:Further reading
1341:
1340:
1331:
1330:
1323:
1282:(10): 5616–21.
1269:
1268:
1264:
1251:
1250:
1246:
1233:
1232:
1228:
1216:
1207:
1195:
1186:
1181:
1132:
1101:View/Edit Mouse
1096:View/Edit Human
1059:
1052:
1049:Location (UCSC)
1035:
1014:
1010:
1006:
1002:
998:
994:
990:
986:
982:
978:
974:
970:
966:
962:
958:
954:
950:
946:
942:
938:
934:
930:
924:
920:
916:
912:
908:
884:
863:
859:
855:
811:
764:ENSG00000273173
657:
626:
550:
541:protein binding
479:
470:
465:
461:
457:
453:
449:
447:layer of retina
445:
441:
437:
433:
419:
408:
403:
399:
397:corpus callosum
395:
391:
387:
383:
379:
375:
371:
357:
301:
288:
280:
270:
269:
268:
261:
241:
218:Gene location (
200:
187:
179:
169:
168:
167:
160:
138:
115:Gene location (
74:
61:
54:
35:
28:
23:
22:
15:
12:
11:
5:
1927:
1925:
1917:
1916:
1911:
1901:
1900:
1895:
1894:
1887:
1880:
1872:
1869:
1868:
1851:
1836:
1835:
1791:
1748:
1716:Human Genetics
1711:
1681:
1661:(4): 2485–97.
1646:
1611:
1568:
1533:
1504:
1461:
1426:
1406:(9): 5024–30.
1391:
1363:(4): 1733–43.
1347:
1345:
1342:
1339:
1338:
1321:
1262:
1244:
1226:
1205:
1183:
1182:
1180:
1177:
1138:is found on a
1131:
1128:
1108:
1107:
1104:
1103:
1098:
1088:
1087:
1081:
1080:
1077:
1076:
1074:
1072:
1065:
1064:
1057:
1050:
1046:
1045:
1042:
1041:
1031:
1030:
1024:
1021:
1020:
926:
925:
899:
895:
894:
891:
890:
880:
879:
873:
870:
869:
851:
850:
844:
840:
839:
836:
835:
827:
826:
820:
817:
816:
804:
803:
797:
791:
790:
787:
786:
778:
777:
771:
768:
767:
759:
758:
752:
746:
745:
742:
741:
733:
732:
726:
723:
722:
714:
713:
707:
701:
700:
695:
690:
686:
685:
675:
674:
671:
670:
659:
658:
656:
655:
650:
645:
640:
634:
632:
628:
627:
625:
624:
619:
614:
609:
604:
599:
594:
589:
584:
579:
574:
569:
564:
558:
556:
552:
551:
549:
548:
543:
538:
532:
530:
526:
525:
515:
514:
511:
510:
507:
506:
503:
502:
495:
489:
488:
485:
484:
476:
475:
472:
471:
469:
468:
464:
460:
456:
452:
448:
444:
440:
436:
432:
428:
425:
424:
413:
410:
409:
407:
406:
402:
398:
394:
393:left ventricle
390:
386:
382:
378:
374:
370:
366:
363:
362:
350:
349:
341:
330:
324:
323:
320:RNA expression
312:
311:
308:
307:
299:
295:
294:
286:
283:
278:
272:
271:
262:
255:
249:
245:
244:
239:
233:
232:
224:
223:
211:
210:
207:
206:
198:
194:
193:
185:
182:
177:
171:
170:
161:
154:
148:
144:
143:
136:
130:
129:
121:
120:
108:
107:
72:
68:
67:
59:
51:
50:
46:
45:
42:
41:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1926:
1915:
1914:Protein stubs
1912:
1910:
1907:
1906:
1904:
1893:
1888:
1886:
1881:
1879:
1874:
1873:
1867:
1865:
1861:
1857:
1852:
1849:
1845:
1840:
1832:
1828:
1823:
1818:
1814:
1810:
1806:
1802:
1798:
1792:
1788:
1784:
1779:
1774:
1770:
1766:
1762:
1758:
1754:
1749:
1745:
1741:
1737:
1733:
1729:
1725:
1722:(6): 553–61.
1721:
1717:
1712:
1708:
1704:
1700:
1696:
1692:
1688:
1682:
1678:
1674:
1669:
1664:
1660:
1656:
1652:
1647:
1643:
1639:
1634:
1629:
1625:
1621:
1617:
1612:
1608:
1604:
1599:
1594:
1590:
1586:
1583:(4): 517–24.
1582:
1578:
1574:
1569:
1565:
1561:
1556:
1551:
1548:(2): 335–46.
1547:
1543:
1539:
1534:
1530:
1526:
1522:
1518:
1515:(1): 317–26.
1514:
1510:
1505:
1501:
1497:
1492:
1487:
1483:
1479:
1476:(2): 585–90.
1475:
1471:
1467:
1462:
1458:
1454:
1449:
1444:
1441:(9): 1861–3.
1440:
1436:
1432:
1427:
1423:
1419:
1414:
1409:
1405:
1401:
1397:
1392:
1388:
1384:
1379:
1374:
1370:
1366:
1362:
1358:
1354:
1349:
1348:
1343:
1334:
1328:
1326:
1322:
1317:
1313:
1308:
1303:
1298:
1293:
1289:
1285:
1281:
1277:
1273:
1266:
1263:
1258:
1254:
1248:
1245:
1240:
1236:
1230:
1227:
1223:
1219:
1214:
1212:
1210:
1206:
1202:
1198:
1193:
1191:
1189:
1185:
1178:
1176:
1174:
1170:
1166:
1162:
1161:translocation
1158:
1157:monocistronic
1153:
1149:
1145:
1141:
1137:
1129:
1127:
1125:
1122:
1118:
1114:
1102:
1097:
1093:
1089:
1086:
1082:
1075:
1073:
1070:
1066:
1062:
1058:
1055:
1051:
1047:
1040:
1038:
1032:
1028:
1025:
1019:
1017:
1013:
1009:
1005:
1001:
997:
993:
989:
985:
981:
977:
973:
969:
965:
961:
957:
953:
949:
945:
941:
937:
933:
927:
923:
919:
915:
911:
907:
903:
900:
896:
889:
887:
881:
877:
874:
868:
866:
862:
858:
852:
848:
845:
843:RefSeq (mRNA)
841:
834:
833:
828:
824:
821:
815:
814:
810:
805:
801:
798:
796:
792:
785:
784:
779:
775:
772:
766:
765:
760:
756:
753:
751:
747:
740:
739:
734:
730:
727:
721:
720:
715:
711:
708:
706:
702:
699:
696:
694:
691:
687:
684:
680:
676:
669:
665:
660:
654:
651:
649:
646:
644:
641:
639:
636:
635:
633:
630:
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567:nuclear speck
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554:
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547:
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533:
531:
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527:
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523:Gene ontology
520:
516:
504:
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389:right auricle
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57:
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19:
1864:expanding it
1853:
1838:
1807:(1): 55–65.
1804:
1800:
1760:
1756:
1719:
1715:
1690:
1686:
1658:
1654:
1626:(1): 571–9.
1623:
1619:
1580:
1576:
1545:
1541:
1512:
1508:
1473:
1470:FEBS Letters
1469:
1438:
1434:
1403:
1399:
1360:
1356:
1279:
1275:
1265:
1256:
1247:
1238:
1229:
1133:
1120:
1112:
1111:
1034:
1016:NP_001365186
1012:NP_001365185
1008:NP_001365184
1004:NP_001365183
1000:NP_001365182
996:NP_001365181
992:NP_001365180
988:NP_001365178
984:NP_001336394
980:NP_001336393
976:NP_001336392
972:NP_001336391
968:NP_001336390
964:NP_001336389
960:NP_001336388
956:NP_001336387
952:NP_001336386
948:NP_001336385
944:NP_001336384
940:NP_001336383
929:
883:
865:NM_001394334
854:
830:
807:
781:
762:
736:
717:
697:
692:
643:RNA splicing
431:hypothalamus
343:
336:
71:External IDs
32:snowboarding
1140:bicistronic
612:nucleoplasm
546:RNA binding
302:59,654,797
289:59,645,197
281:7|7 B5
201:24,977,850
188:24,954,986
49:Identifiers
1903:Categories
1224:, May 2017
1203:, May 2017
1179:References
455:cerebellum
347:(ortholog)
84:HomoloGene
1037:NP_149409
936:NP_073719
932:NP_073718
922:NP_073717
918:NP_073716
914:NP_003088
910:NP_073715
906:NP_005669
886:NM_033174
861:NM_022804
857:NM_005678
683:Orthologs
572:cytoplasm
92:GeneCards
1831:16344560
1787:16116039
1744:26493956
1736:15014980
1707:11726556
1677:11696545
1642:10617653
1316:10318933
1220:–
1199:–
1130:Function
1085:Wikidata
662:Sources:
622:U2 snRNP
617:U1 snRNP
597:U4 snRNP
577:U5 snRNP
467:epiblast
1856:protein
1822:1356129
1778:1188517
1607:8845846
1598:6057871
1564:8571960
1555:1914536
1529:8363612
1500:2753153
1478:Bibcode
1457:2528429
1422:2522449
1387:2522186
1284:Bibcode
1222:Ensembl
1201:Ensembl
1117:protein
795:UniProt
750:Ensembl
689:Species
668:QuickGO
562:nucleus
322:pattern
180:15q11.2
80:1891236
56:Aliases
1829:
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1785:
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1742:
1734:
1705:
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1527:
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1420:
1385:
1378:331831
1375:
1314:
1304:
1071:search
1069:PubMed
832:Q9WU12
813:P63162
809:Q9Y675
705:Entrez
493:BioGPS
1854:This
1740:S2CID
1307:21909
1148:exons
1121:SNURF
1115:is a
738:84704
698:Mouse
693:Human
664:Amigo
405:gonad
345:Mouse
338:Human
285:Start
220:Mouse
184:Start
117:Human
96:SNURF
88:36493
63:SNURF
40:SNURF
18:SNURF
1860:stub
1827:PMID
1783:PMID
1732:PMID
1703:PMID
1673:PMID
1638:PMID
1603:PMID
1560:PMID
1525:PMID
1496:PMID
1453:PMID
1418:PMID
1383:PMID
1312:PMID
1124:gene
719:8926
328:Bgee
276:Band
237:Chr.
175:Band
134:Chr.
1817:PMC
1809:doi
1773:PMC
1765:doi
1724:doi
1720:114
1695:doi
1663:doi
1659:277
1628:doi
1624:275
1593:PMC
1585:doi
1550:PMC
1517:doi
1513:195
1486:doi
1474:250
1443:doi
1408:doi
1404:264
1373:PMC
1365:doi
1302:PMC
1292:doi
1171:or
501:n/a
298:End
197:End
100:OMA
76:MGI
1905::
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1359:.
1355:.
1324:^
1310:.
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1290:.
1280:96
1278:.
1274:.
1255:.
1237:.
1208:^
1187:^
1126:.
666:/
304:bp
291:bp
203:bp
190:bp
98:;
94::
90:;
86::
82:;
78::
1891:e
1884:t
1877:v
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20:)
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