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In his most recent work, he and colleague/collaborator Noemi Mirkin have proposed a new paradigm in the field of protein folding they term "milieu folding" demonstrating that the presence of particular molecules in the surrounding aqueous environment of a protein molecule ("milieu") can alter the
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Mirkin, Noemi G.; Krimm, Samuel (July 2020). "Hydrogen sulfide concentration in the milieu of the hydrated alanine dipeptide determines its polyproline II‐beta propensity: Main chain contribution to the energetic origin of the formation of amyloid".
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He has published over 300 peer-reviewed articles, on the infrared and Raman spectroscopy of synthetic polymers and proteins, and in the field of theoretical and computational studies of the structures of such macromolecules.
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Mirkin, Noemi G.; Krimm, Samuel (2018). "Milieu-Initiated
Inversion of the Aqueous Polyproline II/β Propensity in the Alanine Tripeptide: Aggregation Origin of the Onset of Amyloid Formation".
316:'s Polymer Physics Prize "For his outstanding experimental studies and theoretical developments in infrared and Ra-man spectroscopy and X-ray scattering from natural and synthetic polymers".
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propensities for the folded structure of the protein. They suggest that this is a more appropriate framework than "misfolding" to explore and understand protein-folding diseases.
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He was the first
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257:(spectroscopy, macromolecules, protein folding). He is professor emeritus and research scientist emeritus at
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489:"American Physical Society, Samuel Krimm, fellow 1959, Polymer Physics Prize 1977"
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Mickens, Ronald E. (2022). "The trailblazing career of Willie Hobbs Moore".
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University of
Michigan College of Literature, Science and the Arts
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University of
Michigan College of Literature, Science and the Arts
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New York
University Tandon School of Engineering alumni
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436:"Samuel Krimm biophysics emeritus faculty page"
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326:From 1967-1972 he was doctoral advisor for
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109:Learn how and when to remove this message
673:Fellows of the American Physical Society
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307:fellow of the American Physical Society
249:(born October 19, 1925) is an American
45:Please improve this article by adding
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516:"Humboldt Prize, Samuel Krimm 1983"
693:People from Morristown, New Jersey
688:Humboldt Research Award recipients
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279:Polytechnic Institute of Brooklyn
162:Polytechnic Institute of Brooklyn
190:APS Polymer Physics Prize (1977)
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678:University of Michigan faculty
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47:secondary or tertiary sources
319:In 1983, he was awarded the
312:In 1977, Krimm received the
683:Princeton University alumni
562:"Samuel Krimm bibliography"
391:Krimm, Samuel (July 2010).
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698:Scientists from New Jersey
494:American Physical Society
399:. University of Michigan.
314:American Physical Society
253:with a research focus in
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668:American biophysicists
541:University of Michigan
397:Faculty Memoir Project
259:University of Michigan
225:University of Michigan
148:Morristown, New Jersey
34:relies excessively on
16:American biophysicist
537:"Biophysics History"
465:Michigan Engineering
295:Princeton University
168:Princeton University
328:Willie Hobbs Moore
305:Krimm was elected
291:physical chemistry
235:Willie Hobbs Moore
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375:10.1063/PT.3.5080
301:Career highlights
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205:Scientific career
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281:(1947), and
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170:(1949, 1950)
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658:1925 births
616:Biopolymers
393:"Biography"
99:August 2024
652:Categories
571:August 29,
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345:References
255:biophysics
215:Biophysics
185:APS Fellow
137:1925-10-19
69:newspapers
36:references
309:in 1959.
275:chemistry
265:Education
251:physicist
277:, from
83:scholar
211:Fields
196:(1983)
187:(1959)
178:Awards
164:(1947)
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285:and
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