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Self-expandable metallic stent

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usually placed on the surface of the patient to mark the area of narrowing on fluoroscopy. The SEMS is placed through the channel of the endoscope into the esophagus over a guidewire, marked on fluoroscopy, and mechanically deployed (using a device that sits outside of the endoscope) such that it expands when in position.
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Long-term complications of SEMS may be related to the underlying tumour being treated: the tumour may grow into the stent wall (tumour ingrowth) or over the end of the stent (tumour overgrowth), leading to obstruction. These complications may be limited by the use of coated stents. Tumour ingrowth or
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Garcia-Cano J; Gonzalez-Huix F; Juzgado D; Igea F; Perez-Miranda M; Lopez-Roses L; Rodriguez A; Gonzalez-Carro P; Yuguero L; Espinos J; Ducons J; Orive V; Rodriguez S. (2006). "Use of self-expanding metal stents to treat malignant colorectal obstruction in general endoscopic practice (with videos)".
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Self-expandable metallic stents are cylindrical in shape, and are devised in a number of diameters and lengths to suit the application in question. They typically consist of cross-hatched, braided or interconnecting rows of metal that are assembled into a tube-like structure. SEMS, when unexpanded,
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Esophageal SEMS are placed after a gastroscopy is performed to identify the area of narrowing. The area may need to be dilated to allow the gastroscope to pass. The tumour is usually better seen with the direct vision of endoscopy than on a fluoroscopic image. As a result, radio-opaque markers are
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caused by esophageal reflux and perforations of the esophagus. SEMS may also be placed in tandem fashion to treat ingrowth or overgrowth tumours, and fractures or migration of other SEMS. For the latter, the second SEMS in usually deployed within the lumen of the first.
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Vakil N, Morris A, Marcon N, Segalin A, Peracchia A, Bethge N, Zuccaro G, Bosco J, Jones W (2001). "A prospective, randomized, controlled trial of covered expandable metal stents in the palliation of malignant esophageal obstruction at the gastroesophageal junction".
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Over time, SEMS may also migrate to a different position that does not help with treatment of the obstructed area. This may be treated with placement of a second SEMS, or endoscopic attempts to reposition or remove the first. Rarely, SEMS may fracture or
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of tumours that obstruct the gastrointestinal tract. When they expand within the lumen, they are able to hold open the structure and allow passage of material, such as food, stool, or other secretions. The usual applications are for cancers of the
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Schmassmann A, Meyenberger C, Knuchel J, Binek J, Lammer F, Kleiner B, Hürlimann S, Inauen W, Hammer B, Scheurer U, Halter F (1997). "Self-expanding metal stents in malignant esophageal obstruction: a comparison between two stent types".
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Song H, Park S, Jung H, Kim S, Kim J, Huh S, Kim T, Kim Y, Park S, Yoon H, Sung K, Min Y (1997). "Benign and malignant esophageal strictures: treatment with a polyurethane-covered retrievable expandable metallic stent".
165:, which is meant for delivery of devices for therapeutic endoscopy. They expand through a deployment device placed at the end of the SEMS, and are held in place against the wall of the luminal surface by friction. 320:
or other water-soluble dye may be placed through the passage to ensure patency of the stent on fluoroscopy. Enteric and colonic SEMS are inserted in a similar fashion, but in the duodenum and colon respectively.
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Fiorini A, Fleischer D, Valero J, Israeli E, Wengrower D, Goldin E (2000). "Self-expandable metal coil stents in the treatment of benign esophageal strictures refractory to conventional therapy: a case series".
1143:"Iatrogenic intussusception of a self-expanding metallic esophageal stent in stent after endoscopic guidewire trauma. Abstract presented at Canadian Association of Gastroenterology Meetings, February 2006" 936:
Schiefke I, Zabel-Langhennig A, Wiedmann M, Huster D, Witzigmann H, Mössner J, Berr F, Caca K (2003). "Self-expandable metallic stents for malignant duodenal obstruction caused by biliary tract cancer".
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Gelbmann C, Ratiu N, Rath H, Rogler G, Lock G, Schölmerich J, Kullmann F (2004). "Use of self-expandable plastic stents for the treatment of esophageal perforations and symptomatic anastomotic leaks".
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Ell C, Hochberger J, May A, Fleig W, Hahn E (1994). "Coated and uncoated self-expanding metal stents for malignant stenosis in the upper GI tract: preliminary clinical experiences with Wallstents".
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are typically used as coatings for SEMS. Covered stents carry the advantage of preventing tumours from growing into the stent, although they run the risk of increased migration after deployment.
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Saxon R, Morrison K, Lakin P, Petersen B, Barton R, Katon R, Keller F (1997). "Malignant esophageal obstruction and esophagorespiratory fistula: palliation with a polyethylene-covered Z-stent".
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Ramirez F, Dennert B, Zierer S, Sanowski R (1997). "Esophageal self-expandable metallic stents--indications, practice, techniques, and complications: results of a national survey".
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Decker P, Lippler J, Decker D, Hirner A (2001). "Use of the Polyflex stent in the palliative therapy of esophageal carcinoma: results in 14 cases and review of the literature".
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Matsushita M, Takakuwa H, Nishio A, Kido M, Shimeno N (2003). "Open-biopsy-forceps technique for endoscopic removal of distally migrated and impacted biliary metallic stents".
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Yoon W, Lee J, Lee K, Lee W, Ryu J, Kim Y, Yoon Y (2006). "A comparison of covered and uncovered Wallstents for the management of distal malignant biliary obstruction".
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images taken to guide placement. Prior to the development of SEMS small enough to pass through the channel of the endoscopy, SEMS were deployed using fluoroscopy alone.
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Holt A, Patel M, Ahmed M (2004). "Palliation of patients with malignant gastroduodenal obstruction with self-expanding metallic stents: the treatment of choice?".
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Mauro M, Koehler R, Baron T (2000). "Advances in gastrointestinal intervention: the treatment of gastroduodenal and colorectal obstructions with metallic stents".
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SEMS and self-expanding plastic stents have also been used for non-malignant conditions that cause narrowing or leaks of the esophagus or colon. These include
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Yoshida H, Mamada Y, Taniai N, Mizuguchi Y, Shimizu T, Aimoto T, Nakamura Y, Nomura T, Yokomuro S, Arima Y, Uchida E, Misawa H, Uchida E, Tajiri T (2006).
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and colon. SEMS are designed to be permanent and, as a result, are often used when the cancer is at an advanced stage and cannot be removed by surgery.
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The complications of SEMS are related to a number of factors. The first is that the endoscopic procedure used to insert a SEMS involves the use of
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that is located at its base is typically cut. A wire is kept in the bile duct, and the SEMS is deployed over the wire in a similar fashion as
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Kauffmann G, Roeren T, Friedl P, Brambs H, Richter G (1990). "Interventional radiological treatment of malignant biliary obstruction".
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Nelson D, Silvis S, Ansel H (1994). "Management of a tracheoesophageal fistula with a silicone-covered self-expanding metal stent".
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of the gastrointestinal tract that obstruct the interior of the tube-like (or luminal) structures of the bowel — namely the
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Conio M, Gostout C (1998). "Photodynamic therapy for the treatment of tumor ingrowth in expandable esophageal stents".
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Cordero J, Moores D (2000). "Self-expanding esophageal metallic stents in the treatment of esophageal obstruction".
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overgrowth can be additionally palliated by the placement of a second stent through the lumen of the first, through
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that are not amenable to surgical therapy. SEMS are used to treat additional complications of cancer, such as
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SEMS may be coated with chemicals designed to prevent tumour ingrowth; these are termed "covered" stents.
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Biliary SEMS are used to palliatively treat tumours of the pancreas or bile duct that obstruct the
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where the surgeon uses an X-ray image to guide insertion, or as an adjunct to endoscopy.
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Vitale G, Davis B, Tran T (2005). "The advancing art and science of endoscopy".
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Schematic of self-expandable metallic stent used to treat vascular abnormalities
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Self-expandable metallic stents are typically inserted at the time of
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The vast majority of SEMS are used to alleviate symptoms caused by
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of the bowel or compression of structures adjacent to the bowel.
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of the tumour tissue in the stent, or through the use of
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Fluoroscopic image of two metal biliary stents in the
1141:Grover SC, Wang CS, Jones MB, Elyas ME, Kortan PP. 50: 42: 18: 161:are small enough to fit through the channel of an 368:medications, which may lead to oversedation, 8: 336:with the assistance of a guidewire and the 801: 799: 206:The primary application of SEMS is in the 194:A plastic self-expanding stent (Polyflex, 24: 823: 412: 262:. In the past they have been used for 15: 593: 591: 589: 587: 585: 7: 250:SEMS are also sometimes used in the 376:. SEMS also expand and can lead to 328:. They are inserted at the time of 292:. The black solid structure is the 271:percutaneous coronary interventions 85:that holds open a structure in the 59: 469:10.1148/radiology.215.3.r00jn30659 239:, duodenal, or pancreatic cancer. 121:. SEMS can also be inserted using 14: 97:, or other secretions related to 812:Journal of Nippon Medical School 882:(10): 956–8, discussion 958–9. 568:10.1148/radiology.202.2.9015055 533:10.1148/radiology.203.3.9169699 404:after endoscopic intervention. 304:, usually with assistance with 290:metallic stent in the esophagus 89:to allow the passage of food, 75:self-expandable metallic stent 32:self-expandable metallic stent 19:Self-expandable metallic stent 1: 1120:10.1016/S0016-5107(03)02335-6 1085:10.1016/S0016-5107(98)70175-0 915:10.1016/S0016-5107(97)70144-5 709:10.1016/S0016-5107(04)02276-X 674:10.1016/S0016-5107(94)70221-7 434:10.1016/j.amjsurg.2005.05.017 231:from esophageal cancer, and 1189: 260:peripheral vascular system 233:gastric outlet obstruction 229:tracheoesophageal fistulas 109:camera—either through the 101:. Surgeons insert SEMS by 1022:10.1016/j.gie.2006.06.034 986:10.1016/j.gie.2005.11.054 288:image of self-expandable 148:Composition and structure 81:) is a metallic tube, or 60: 23: 390:argon plasma coagulation 296:used to place the stent. 745:10.1067/mge.2000.107709 361: 297: 157: 87:gastrointestinal tract 782:10.1055/s-2004-825656 639:10.1007/s004640090099 355: 284: 155: 30:Endoscopic view of a 951:10.1067/mge.2003.362 394:photodynamic therapy 264:saphenous vein graft 34:used to palliate an 1173:Implants (medicine) 1108:Gastrointest Endosc 1073:Gastrointest Endosc 1010:Gastrointest Endosc 974:Gastrointest Endosc 939:Gastrointest Endosc 903:Gastrointest Endosc 825:10.1272/jnms.73.164 733:Gastrointest Endosc 697:Gastrointest Endosc 662:Gastrointest Endosc 1046:Am J Gastroenterol 600:Am J Gastroenterol 493:Am J Gastroenterol 362: 298: 158: 342:esophageal stents 338:sphincter of Oddi 254:, usually in the 244:peptic strictures 196:Boston Scientific 71: 70: 36:esophageal cancer 1180: 1168:Gastroenterology 1153: 1152: 1150: 1149: 1138: 1132: 1131: 1103: 1097: 1096: 1068: 1062: 1061: 1040: 1034: 1033: 1004: 998: 997: 969: 963: 962: 933: 927: 926: 898: 892: 891: 871: 865: 864: 849:Eur J Surg Oncol 844: 838: 837: 827: 803: 794: 793: 763: 757: 756: 727: 721: 720: 692: 686: 685: 657: 651: 650: 622: 616: 615: 595: 580: 579: 551: 545: 544: 515: 509: 508: 487: 481: 480: 452: 446: 445: 417: 358:common bile duct 326:common bile duct 142:common bile duct 64:edit on Wikidata 56:gastroenterology 28: 16: 1188: 1187: 1183: 1182: 1181: 1179: 1178: 1177: 1158: 1157: 1156: 1147: 1145: 1140: 1139: 1135: 1105: 1104: 1100: 1070: 1069: 1065: 1042: 1041: 1037: 1006: 1005: 1001: 980:(7): 996–1000. 971: 970: 966: 935: 934: 930: 900: 899: 895: 873: 872: 868: 846: 845: 841: 805: 804: 797: 765: 764: 760: 729: 728: 724: 694: 693: 689: 659: 658: 654: 624: 623: 619: 606:(9): 1496–500. 597: 596: 583: 553: 552: 548: 517: 516: 512: 489: 488: 484: 454: 453: 449: 419: 418: 414: 410: 350: 279: 268:coronary artery 252:vascular system 204: 150: 67: 38: 12: 11: 5: 1186: 1184: 1176: 1175: 1170: 1160: 1159: 1155: 1154: 1133: 1098: 1063: 1035: 1016:(6): 914–920. 999: 964: 928: 893: 866: 855:(4): 397–403. 839: 795: 758: 722: 687: 652: 633:(12): 1444–7. 617: 581: 546: 510: 482: 447: 411: 409: 406: 386:electrocautery 349: 346: 278: 275: 203: 200: 149: 146: 119:endoprosthesis 105:, inserting a 69: 68: 61: 58: 57: 54: 48: 47: 44: 40: 39: 29: 21: 20: 13: 10: 9: 6: 4: 3: 2: 1185: 1174: 1171: 1169: 1166: 1165: 1163: 1144: 1137: 1134: 1129: 1125: 1121: 1117: 1113: 1109: 1102: 1099: 1094: 1090: 1086: 1082: 1078: 1074: 1067: 1064: 1059: 1055: 1052:(6): 1791–6. 1051: 1047: 1039: 1036: 1031: 1027: 1023: 1019: 1015: 1011: 1003: 1000: 995: 991: 987: 983: 979: 975: 968: 965: 960: 956: 952: 948: 944: 940: 932: 929: 924: 920: 916: 912: 908: 904: 897: 894: 889: 885: 881: 877: 870: 867: 862: 858: 854: 850: 843: 840: 835: 831: 826: 821: 817: 813: 809: 802: 800: 796: 791: 787: 783: 779: 775: 771: 770: 762: 759: 754: 750: 746: 742: 739:(2): 259–62. 738: 734: 726: 723: 718: 714: 710: 706: 703:(6): 1010–7. 702: 698: 691: 688: 683: 679: 675: 671: 667: 663: 656: 653: 648: 644: 640: 636: 632: 628: 621: 618: 613: 609: 605: 601: 594: 592: 590: 588: 586: 582: 577: 573: 569: 565: 562:(2): 349–54. 561: 557: 550: 547: 542: 538: 534: 530: 527:(3): 747–52. 526: 522: 514: 511: 506: 502: 498: 494: 486: 483: 478: 474: 470: 466: 463:(3): 659–69. 462: 458: 451: 448: 443: 439: 435: 431: 428:(2): 228–33. 427: 423: 416: 413: 407: 405: 403: 397: 395: 391: 387: 381: 379: 375: 374:drug reaction 371: 367: 359: 354: 348:Complications 347: 345: 343: 339: 335: 331: 327: 322: 319: 313: 311: 307: 303: 295: 291: 287: 283: 276: 274: 272: 269: 265: 261: 257: 253: 248: 245: 240: 238: 234: 230: 226: 222: 218: 214: 209: 201: 199: 197: 192: 190: 186: 182: 178: 175: 171: 166: 164: 154: 147: 145: 143: 139: 135: 131: 126: 124: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 65: 55: 53: 49: 45: 41: 37: 33: 27: 22: 17: 1146:. 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Index


esophageal cancer
Specialty
edit on Wikidata
stent
gastrointestinal tract
chyme
stool
digestion
endoscopy
fibre optic
mouth
colon
fluoroscopy
cancers
esophagus
duodenum
common bile duct

endoscope
Nitinol
shape memory
nickel
titanium
polyurethane
polyethylene
Boston Scientific
palliation
esophagus
pancreas

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