Knowledge (XXG)

Sharon R. Browning

Source πŸ“

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Browning is known for her research developing statistical methods for analysis of population genetic data. Her early work established the used of Markov chain modeling to examine association based genome mapping. Her work addresses how to handle missing data in whole-genome association studies. She
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Harris, Daniel N.; Kessler, Michael D.; Shetty, Amol C.; Weeks, Daniel E.; Minster, Ryan L.; Browning, Sharon; Cochrane, Ethan E.; Deka, Ranjan; Hawley, Nicola L.; Reupena, Muagututiβ€˜a Sefuiva; Naseri, Take (2020-04-28).
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has also defined the use of group association tests and examined relatedness of individuals based on shared gene content. Browning has also examined the genetic history of the
1010: 520:"Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering" 170:"Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering" 1025: 871: 437: 1000: 213:"A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals" 123: 1015: 158:
in at least two separate events, the second of which may have occurred as humans migrated eastward into Asia and Oceania.
355: 98:, and a research professor with its Department of Biostatistics. Her research has various implications for the field of 379: 322: 115: 95: 119: 1005: 111: 684: 421: 75: 1020: 793: 400: 848:"Researchers use 21st century genomics to estimate Samoan population dynamics over 3,000 years" 154:
into modern human DNA. In 2018, they discovered that humans in the distant past had mated with
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Browning, Sharon R.; Browning, Brian L.; Zhou, Ying; Tucci, Serena; Akey, Joshua M. (2018).
819: 801: 751: 743: 696: 655: 637: 596: 580: 539: 531: 490: 474: 285: 267: 232: 224: 189: 181: 70: 569:"Missing data imputation and haplotype phase inference for genome-wide association studies" 127: 981: 797: 700: 130:, and the University of Auckland before moving to the University of Washington in 2010. 985: 955: 930: 824: 781: 756: 731: 660: 625: 601: 568: 544: 519: 495: 462: 290: 255: 237: 212: 194: 169: 994: 151: 147: 931:"Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture" 323:"A Blended Family: Her Mother Was Neanderthal, Her Father Something Else Entirely" 642: 624:
Madsen, Bo Eskerod; Browning, Sharon R. (2009-02-13). Schork, Nicholas J. (ed.).
272: 626:"A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic" 256:"A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic" 99: 946: 747: 228: 847: 584: 91: 909: 815: 708: 651: 592: 486: 334: 281: 806: 155: 964: 833: 765: 732:"High-Resolution Detection of Identity by Descent in Unrelated Individuals" 716: 685:"Identity by Descent Between Distant Relatives: Detection and Applications" 669: 610: 553: 504: 299: 246: 203: 898:"Humans bred with this mysterious species more than once, new study shows" 356:"Ancient Human Groups Mated With the Mysterious Denisovans at Least Twice" 140: 52: 463:"Multilocus Association Mapping Using Variable-Length Markov Chains" 535: 478: 380:"Mysterious Denisovans interbred with modern humans more than once" 185: 58: 146:
Browning and her research group also study the traces of genetic
872:"Multiple lines of mysterious ancient humans interbred with us" 423:
Monte Carlo likelihood calculation for identity by descent data
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Monte Carlo likelihood calculation for identity by descent data
401:"Modern humans interbred with Denisovans twice in history" 683:
Browning, Sharon R.; Browning, Brian L. (2012-12-15).
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Madsen, Bo Eskerod; Browning, Sharon R. (2009-02-13).
69: 51: 36: 28: 21: 730:Browning, Sharon R.; Browning, Brian L. (2010). 518:Browning, Sharon R.; Browning, Brian L. (2007). 211:Browning, Brian L.; Browning, Sharon R. (2009). 168:Browning, Sharon R.; Browning, Brian L. (2007). 786:Proceedings of the National Academy of Sciences 118:. Following her Ph.D., she held positions at 114:(1995) and earned her Ph.D. in 1999 from the 8: 18: 954: 823: 805: 755: 659: 641: 600: 543: 494: 289: 271: 236: 193: 782:"Evolutionary history of modern Samoans" 313: 736:The American Journal of Human Genetics 524:The American Journal of Human Genetics 467:The American Journal of Human Genetics 217:The American Journal of Human Genetics 174:The American Journal of Human Genetics 7: 701:10.1146/annurev-genet-110711-155534 461:Browning, Sharon R. (2006-06-01). 14: 354:Dvorsky, George (15 March 2018). 1011:University of Washington faculty 896:Guarino, Ben (March 15, 2018). 124:North Carolina State University 110:Browning has a B.Sc. from the 1: 643:10.1371/journal.pgen.1000384 567:Browning, Sharon R. (2008). 273:10.1371/journal.pgen.1000384 321:Zimmer, Carl (2018-08-22). 1042: 1026:American women geneticists 947:10.1016/j.cell.2018.02.031 748:10.1016/j.ajhg.2010.02.021 229:10.1016/j.ajhg.2009.01.005 689:Annual Review of Genetics 585:10.1007/s00439-008-0568-7 420:Browning, Sharon (1999). 81: 44: 984:publications indexed by 120:Texas A&M University 116:University of Washington 96:University of Washington 40:University of Washington 1001:Statistical geneticists 807:10.1073/pnas.1913157117 112:University of Auckland 16:Statistical geneticist 162:Selected publications 76:Elizabeth A. Thompson 1016:American geneticists 382:. CNN. 16 March 2018 106:Education and career 88:Sharon Ruth Browning 798:2020PNAS..117.9458H 982:Sharon R. Browning 327:The New York Times 23:Sharon R. Browning 792:(17): 9458–9465. 90:is a statistical 85: 84: 46:Scientific career 1033: 969: 968: 958: 926: 920: 919: 917: 916: 893: 887: 886: 884: 883: 868: 862: 861: 859: 858: 852:Brown University 844: 838: 837: 827: 809: 776: 770: 769: 759: 727: 721: 720: 680: 674: 673: 663: 645: 621: 615: 614: 604: 564: 558: 557: 547: 530:(5): 1084–1097. 515: 509: 508: 498: 458: 452: 451: 449: 447: 442: 434: 428: 427: 426:(Thesis thesis). 417: 411: 410: 408: 407: 397: 391: 390: 388: 387: 376: 370: 369: 367: 366: 351: 345: 344: 342: 341: 318: 303: 293: 275: 250: 240: 207: 197: 180:(5): 1084–1097. 71:Doctoral advisor 65: 19: 1041: 1040: 1036: 1035: 1034: 1032: 1031: 1030: 991: 990: 978: 973: 972: 941:(1): 53–61.e9. 928: 927: 923: 914: 912: 902:Washington Post 895: 894: 890: 881: 879: 870: 869: 865: 856: 854: 846: 845: 841: 778: 777: 773: 729: 728: 724: 682: 681: 677: 636:(2): e1000384. 623: 622: 618: 566: 565: 561: 517: 516: 512: 460: 459: 455: 445: 443: 440: 436: 435: 431: 419: 418: 414: 405: 403: 399: 398: 394: 385: 383: 378: 377: 373: 364: 362: 353: 352: 348: 339: 337: 320: 319: 315: 310: 266:(2): e1000384. 253: 210: 167: 164: 136: 128:GlaxoSmithKline 108: 63: 37:Alma mater 24: 17: 12: 11: 5: 1039: 1037: 1029: 1028: 1023: 1018: 1013: 1008: 1003: 993: 992: 989: 988: 986:Google Scholar 977: 976:External links 974: 971: 970: 921: 888: 863: 839: 771: 742:(4): 526–539. 722: 695:(1): 617–633. 675: 616: 579:(5): 439–450. 573:Human Genetics 559: 536:10.1086/521987 510: 479:10.1086/503876 473:(6): 903–913. 453: 429: 412: 392: 371: 346: 312: 311: 309: 306: 305: 304: 251: 223:(2): 210–223. 208: 186:10.1086/521987 163: 160: 152:archaic humans 135: 132: 107: 104: 83: 82: 79: 78: 73: 67: 66: 55: 49: 48: 42: 41: 38: 34: 33: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1038: 1027: 1024: 1022: 1019: 1017: 1014: 1012: 1009: 1007: 1006:Living people 1004: 1002: 999: 998: 996: 987: 983: 980: 979: 975: 966: 962: 957: 952: 948: 944: 940: 936: 932: 925: 922: 911: 907: 903: 899: 892: 889: 877: 873: 867: 864: 853: 849: 843: 840: 835: 831: 826: 821: 817: 813: 808: 803: 799: 795: 791: 787: 783: 775: 772: 767: 763: 758: 753: 749: 745: 741: 737: 733: 726: 723: 718: 714: 710: 706: 702: 698: 694: 690: 686: 679: 676: 671: 667: 662: 657: 653: 649: 644: 639: 635: 631: 630:PLOS Genetics 627: 620: 617: 612: 608: 603: 598: 594: 590: 586: 582: 578: 574: 570: 563: 560: 555: 551: 546: 541: 537: 533: 529: 525: 521: 514: 511: 506: 502: 497: 492: 488: 484: 480: 476: 472: 468: 464: 457: 454: 439: 438:"Browning CV" 433: 430: 425: 424: 416: 413: 402: 396: 393: 381: 375: 372: 361: 357: 350: 347: 336: 332: 328: 324: 317: 314: 307: 301: 297: 292: 287: 283: 279: 274: 269: 265: 261: 260:PLOS Genetics 257: 252: 248: 244: 239: 234: 230: 226: 222: 218: 214: 209: 205: 201: 196: 191: 187: 183: 179: 175: 171: 166: 165: 161: 159: 157: 153: 149: 148:introgression 144: 142: 133: 131: 129: 125: 121: 117: 113: 105: 103: 101: 97: 93: 89: 80: 77: 74: 72: 68: 61: 60: 56: 54: 50: 47: 43: 39: 35: 31: 27: 20: 938: 934: 924: 913:. 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Index

Thesis
Monte Carlo likelihood calculation for identity by descent data
Doctoral advisor
Elizabeth A. Thompson
geneticist
University of Washington
biogenetics
University of Auckland
University of Washington
Texas A&M University
North Carolina State University
GlaxoSmithKline
Samoans
introgression
archaic humans
Denisovans
"Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering"
doi
10.1086/521987
PMC
2265661
PMID
17924348
"A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals"
doi
10.1016/j.ajhg.2009.01.005
PMC
2668004
PMID
19200528

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