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plants was found to occur in all organs examined from the seed stage to the flowering stage of somatic plant development. Recombination frequencies were typically in the range of 10 to 10 events per
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131:
450:"UV-damage-mediated induction of homologous recombination in Arabidopsis is dependent on photosynthetically active radiation"
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requires a recombinational process that was defective in the mutants studied. In nature, plants are continuously exposed to
130:. The mutants were also deficient in somatic homologous recombination. These findings suggest that repair of some types of
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Lee MH, Siddoway B, Kaeser GE, Segota I, Rivera R, Romanow WJ, Liu CS, Park C, Kennedy G, Long T, Chun J (November 2018).
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that is inherited by its daughter cells. The term is usually reserved for large-scale alterations of DNA such as
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Ramel C, Cederberg H, Magnusson J, et al. (1996). "Somatic recombination, gene amplification and cancer".
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138:(280–320 nm) radiation, a component of sunlight that damages the DNA of somatic cells. Cyclobutane
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show greater APP gene diversity due to somatic recombination than neurons from healthy individuals.
199:"Processing of switch transcripts is required for targeting of antibody class switch recombination"
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146:, homologous recombination appears to be directly involved in repairing CPD damage.
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Alteration of the DNA of a somatic cell that is inherited by its daughter cells
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also proved to be simultaneously hypersensitive to the DNA damaging agents
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286:"Somatic APP gene recombination in Alzheimer's disease and normal neurons"
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46:. Somatic recombination occurs physiologically in the assembly of the
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398:"Arabidopsis thaliana mutants altered in homologous recombination"
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Gellert M (1992). "Molecular analysis of V(D)J recombination".
77:, somatic recombination occurs in the gene that encodes the
66:. Somatic recombination is also important in the process of
346:"Intrachromosomal homologous recombination in whole plants"
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Ries G, Buchholz G, Frohnmeyer H, Hohn B (November 2000).
517:
197:
Hein K, Lorenz MG, Siebenkotten G, et al. (1998).
344:Swoboda P, Gal S, Hohn B, Puchta H (January 1994).
142:(CPD) are a type of damage induced by UV-B. In
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396:Masson JE, Paszkowski J (October 1997).
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176:10.1146/annurev.ge.26.120192.002233
30:, is an alteration of the DNA of a
516:. You can help Knowledge (XXG) by
362:10.1002/j.1460-2075.1994.tb06283.x
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118:selected for hypersensitivity to
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85:from individuals with sporadic
1:
260:10.1016/0027-5107(95)00243-x
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36:chromosomal translocations
310:10.1038/s41586-018-0718-6
79:amyloid precursor protein
454:Proc Natl Acad Sci U S A
414:10.1073/pnas.94.21.11731
402:Proc Natl Acad Sci U S A
99:homologous recombination
73:In neurons of the human
215:10.1084/jem.188.12.2369
128:methyl methanesulfonate
466:10.1073/pnas.230251897
58:), as well as in the
24:genetic recombination
20:Somatic recombination
104:Arabidopsis thaliana
22:, as opposed to the
302:2018Natur.563..639L
87:Alzheimer's disease
56:V(D)J recombination
42:and not applied to
568:Molecular biology
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296:(7733): 639–645.
140:pyrimidine dimers
97:Intrachromosomal
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64:immunoglobulins
60:class switching
52:T-cell receptor
48:B cell receptor
44:point mutations
26:that occurs in
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32:somatic cell
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144:A. thaliana
124:mitomycin C
113:A. thaliana
557:Categories
170:: 425–46.
150:References
132:DNA damage
248:Mutat Res
203:J Exp Med
40:deletions
563:Mutation
510:genetics
484:11069284
328:30464338
432:9326679
380:8313893
319:6391999
298:Bibcode
268:8692194
233:9858523
224:2212419
184:1482120
126:and/or
116:mutants
83:Neurons
54:genes (
28:meiosis
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371:394832
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350:EMBO J
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290:Nature
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109:genome
93:Plants
81:APP.
508:This
475:27240
423:23619
75:brain
514:stub
480:PMID
428:PMID
376:PMID
324:PMID
264:PMID
229:PMID
180:PMID
136:UV-B
50:and
38:and
470:PMC
462:doi
418:PMC
410:doi
366:PMC
358:doi
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306:doi
294:563
256:doi
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219:PMC
211:doi
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101:in
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