Knowledge (XXG)

Apicomplexan life cycle

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Herwaldt; Persing, DH; Précigout, EA; Goff, WL; Mathiesen, DA; Taylor, PW; Eberhard, ML; Gorenflot, AF; et al. (1 April 1996). "A Fatal Case of Babesiosis in Missouri: Identification of Another Piroplasm That Infects Humans".
492:, animal) is the activated, intracellular feeding stage in the apicomplexan life cycle. After gorging itself on its host, the trophozoite undergoes schizogony and develops into a schizont, later releasing merozoites. 372:
and then rapidly reproduce asexually. The red blood cell host is destroyed by this process, which releases many new merozoites that go on to find new blood-borne hosts. Merozoites are motile. Before
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that takes place within a host cell. During this stage, the parasite infects the host's cells and then replicates its own nucleus and induces cell segmentation in a form of asexual reproduction. In
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Not all apicomplexa develop all the following cellular varieties and division methods. This presentation is intended as an outline of a hypothetical generalised apicomplexan organism.
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Zhou, M.; Liu, Q.; Wongsrichanalai, C.; Suwonkerd, W.; Panart, K.; Prajakwong, S.; Pensiri, A.; Kimura, M.; Matsuoka, H.; Ferreira, M. U.; Isomura, S.; Kawamoto, F. (April 1998).
935:"High prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai-Myanmar border, as revealed by acridine orange staining and PCR-based diagnoses" 263: 235:. It involves an unusual process in which two daughter cells are produced inside a mother cell, which is then consumed by the offspring prior to their separation. 515:, animal) is a quiescent parasite stage that is best known for its "... probable association with latency and relapse in human malarial infections caused by 323:), where they multiply. Cells infected with sporozoites eventually burst, releasing merozoites into the bloodstream. Sporozoites are motile and they move by 55:
stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle. Each stage in the life cycle of an
38:: 1-polar ring, 2-conoid, 3-micronemes, 4-rhoptries, 5-nucleus, 6-nucleolus, 7-mitochondria, 8-posterior ring, 9-alveoli, 10-golgi apparatus, 11-micropore. 777:
size, probably reflecting a reduced need for DNA repair of genomes with smaller information content. Reduced DNA repair may help explain the elevated
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Rigoulet, Jacques; Hennache, Alain; Lagourette, Pierre; George, Catherine; Longeart, Loïc; Le Net, Jean-Loïc; Dubey, Jitender P. (20 November 2014).
836: 1075: 846: 727: 315:, for instance, the sporozoites are cells that develop in the mosquito's salivary glands, leave the mosquito during a blood meal, and enter 862: 691: 602:, animal), contrasting with a bradyzoite, is a form typified by rapid growth and replication. Tachyzoites are the motile forms of those 1002: 819: 709: 459:
to form a thick-walled structure known as an oocyst under the mosquito's outer gut lining. Ookinetes are motile and they move by
274: 167:), which are released into the blood when the host cell ruptures. Organisms whose life cycles rely on this process include 661:
develops within the spore, which acts to protect it during transfer to new hosts. Organisms that create oocysts include
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Sinden, RE; Talman, A; Marques, SR; Wass, MN; Sternberg, MJE (August 2010). "The flagellum in malarial parasites".
48: 1369: 1311:"Proteome size reduction in Apicomplexans is linked with loss of DNA repair and host redundant pathways" 256: 52: 1364: 226: 124: 64: 657:, bladder) is a hardy, thick-walled spore, able to survive for lengthy periods outside a host. The 250: 1310: 1249: 1202: 964: 915: 567:, bradyzoites microscopically present as clusters enclosed by an irregular crescent-shaped wall ( 868: 1340: 1284: 1241: 1194: 1138: 1096: 1053: 998: 956: 907: 842: 815: 559: 269: 231: 187: 83: 986: 1330: 1322: 1276: 1233: 1186: 1130: 1043: 1035: 946: 903: 899: 460: 324: 89: 120:, although the latter is sometimes referred to as schizogony, despite its general meaning. 675: 362:, merozoites form the first phase of the internal life cycle of coccidian. In the case of 1105:
A merozoite before schizogony, as in the exoerythrocytic phase of the development of the
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capable of moving spontaneously. It penetrates epithelial cells lining the midgut of
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agent after sporozoite invasion of the hepatocyte and before multiple division.
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Markus, Miles B. (16 July 2010). "Malaria: Origin of the Term 'Hypnozoite'".
195: 169: 1344: 1245: 1198: 1142: 1057: 1288: 960: 911: 778: 774: 669: 603: 563:, among others responsible for parasitic infections. In chronic (latent) 551: 456: 355: 17: 254:
An ookinete (motile), a sporozoite (motile) and a merozoite (motile) of
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Endopolygeny is the division into several organisms at once by internal
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Derilus, D.; Rahman, M.Z.; Serrano, A.E.; Massey, S.E. (January 2021).
762: 717: 699: 663: 623: 239: 203: 175: 626:, tachyzoites divide by endodyogeny and endopolygeny. Also known as a 754: 658: 452: 413: 206:
and multiple fission. This results in the production of sporozoites.
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Markus, M. B. (15 November 2016). "Terms for coccidian merozoites".
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Markus, Miles B. (22 March 2018). "Biological concepts in recurrent
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Sporogony is a type of sexual and asexual reproduction. It involves
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process of apicomplexa. After infecting a host cell, a trophozoite (
416:-forming cells. A male gametocyte divides to give many flagellated 163:
schizont into numerous identical daughter cells called merozoites (
316: 262: 249: 29: 750: 568: 630:(same journal reference as for "bradyzoic merozoite", above). 997:(3rd ed.). Cambridge University Press. pp. 99–103. 651: 643: 596: 588: 544: 536: 509: 501: 486: 478: 445: 437: 406: 398: 348: 340: 303: 295: 571:) in infected muscle and brain tissues. Also known as a 309:, animal) is the cell form that infects new hosts. In 131:) increases in size while repeatedly replicating its 773:
genes tend to be lost by apicomplexans with reduced
420:, whereas the female gametocyte differentiates to a 139:. During this process, the organism is known as a 88:Apicomplexans (sporozoans) replicate via ways of 523:". Hypnozoites are directly sporozoite-derived. 1269:Annals of Tropical Medicine & Parasitology 985:Smyth, James Desmond; Wakelin, Derek (1994). 781:rates in pathogens with reduced genome size. 550:, animal) is a sessile, slow-growing form of 34:Cellular structure of a typical, generalised 8: 939:Tropical Medicine and International Health 1334: 1047: 1020:"Toxoplasmosis in a bar-shouldered dove ( 950: 1072:"Malaria - Life Cycle Of Plasmodium.swf" 835:Yoshinori Tanada; Harry K. Kaya (1993). 412:, cell) is a name given to a parasite's 980: 978: 904:10.7326/0003-4819-124-7-199604010-00004 802: 687: 1304: 1302: 1300: 1298: 376:, the merozoite is also known as the 7: 812:Marine fish parasitology: an outline 753:loss was studied in 41 apicomplexan 995:Introduction to animal parasitology 765:biosynthesis could be explained by 209:Other forms of replication include 25: 1315:Infection, Genetics and Evolution 1179:Journal of the History of Biology 1101:Farlex Partner Medical Dictionary 1024:) from the Zoo of Clères, France" 769:redundancy with the host. Also, 952:10.1046/j.1365-3156.1998.00223.x 841:. Gulf Professional Publishing. 726: 708: 690: 275:transmission electron microscopy 229:, favoured by parasites such as 1157:"Ookinete (Medical Dictionary)" 1123:Current Opinion in Microbiology 622:. Typically infecting cellular 1281:10.1080/00034983.1987.11812147 225:. Endodyogeny is a process of 78:Methods of asexual replication 1: 867:. MSN Encarta. Archived from 757:. Loss of genes employed in 164: 128: 1327:10.1016/j.meegid.2020.104642 652: 644: 597: 589: 545: 537: 510: 502: 487: 479: 446: 438: 407: 399: 349: 341: 304: 296: 892:Annals of Internal Medicine 791:Trematode life cycle stages 354:, animal) is the result of 1386: 451:, motile) is a fertilised 81: 59:organism is typified by a 1238:10.1017/S003118201800032X 1191:10.1007/s10739-010-9239-3 1135:10.1016/j.mib.2010.05.016 1074:. esnips. Archived from 1040:10.1051/parasite/2014062 810:Jadwiga Grabda (1991). 202:, which is followed by 49:intracellular parasites 277: 260: 246:Glossary of cell types 125:asexually reproductive 96:). These ways include 39: 27:Apicomplexa life cycle 864:Schizogony definition 266: 257:Plasmodium falciparum 253: 198:, the formation of a 33: 368:, merozoites infect 227:asexual reproduction 159:next subdivides the 1078:on 21 November 2009 628:tachyzoic merozoite 573:bradyzoic merozoite 267:Two tachyzoites of 1022:Geopelia humeralis 814:. 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Index

Sporogony

apicomplexan
Apicomplexans
intracellular parasites
life cycle
apicomplexan
morphology
biochemistry
Fission (biology)
multiple fission
schizogony
asexually reproductive
see glossary below
nucleus
organelles
Cytokinesis
multinucleated
see glossary below
Theileria
Babesia
Plasmodium
Toxoplasma gondii
karyogamy
zygote
meiosis
asexual reproduction
Toxoplasma gondii
budding

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