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development. This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur and the tumor becomes more aggressive and acquires greater malignant potential. Together with the progression, more and more
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Compton C (2020). "Cancer initiation, promotion, and progression and the acquisition of key behavioral traits.".
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in 2007 and the onset of phenotypical changes in 2014.
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occurs. This may be evident as nuclear polymorphism.
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