164:
Studies in worms have shown that TRPN mutants have locomotion defects, as well as a decreased basal slowing response, which is a reduction in rate of motion that is induced by contact with a food source. This result further strengthens the hypothesis that TRPN is vital to proprioception.
224:
The following is a list of genes encoding TRPN organized by the organism in which they are found. Gene names are specific to the organism and to the way in which they were discovered, which is why the gene name may not explicitly be "TRPN". Links to the
184:
of TRPN function result in deafness as well as imbalance, suggesting a dual role in hearing as well as proprioception. Immunostaining studies in frog embryos have shown localization of TRPN at the tips of mechanosensory cilia in the
3433:
197:
cells, suggesting a role in a variety of mechanosensory functions. TRPN localizes to the kinocilia, not stereocilia, of amphibian hair cells, suggesting the presence of two distinct classes of mechanosensitive channel.
148:
techniques, that TRPN is localized at the distal end of motile mechanosensory cilia in
Johnston's organ. However, TRPN is not required for transduction of mechanical stimuli in larvae or adult flies, suggesting that the
3426:
3419:
1974:
2884:
2619:
1871:
1804:
226:
812:"NOMPC, a Member of the TRP Channel Family, Localizes to the Tubular Body and Distal Cilium of Drosophila Campaniform and Chordotonal Receptor Cells"
2815:
2798:
2793:
2788:
2783:
2820:
1918:
1190:
4448:
4414:
3442:
2872:
2053:
23:
5185:
4301:
4041:
2770:
1791:
1207:
593:
Jin, Peng; Bulkley, David; Guo, Yanmeng; Zhang, Wei; Guo, Zhenhao; Huynh, Walter; Wu, Shenping; Meltzer, Shan; Cheng, Tong (July 2017).
2556:
5140:
4276:
4011:
5263:
4576:
3149:
2148:
1926:
1242:
5150:
4571:
4566:
4016:
3171:
109:, TRPN responds to impinging mechanical forces. Studies in TRPN deficient adult fruit flies and larvae have shown that these
4551:
4546:
3493:
3380:
1291:
5259:
4536:
4097:
2746:
1658:
712:"A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca2+-permeable channel in the yeast vacuolar membrane"
3021:
920:"Sound response mediated by the TRP channels NOMPC, NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae"
33:, which is a diverse group of proteins thought to be involved in mechanoreception. The TRPN gene was given the name
1199:
1183:
4901:
3665:
3375:
1585:
1078:
Schüler, Andreas; Schmitz, Gregor; Reft, Abigail; Özbek, Suat; Thurm, Ulrich; Bornberg-Bauer, Erich (June 2015).
169:
studies of single channels in worms have shown that TRPN responds to mechanical stimuli and has a preference for
476:"Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells"
4651:
4561:
4556:
4541:
4358:
3858:
3488:
3483:
3365:
1626:
1502:
86:
663:"Hypothesis: A helix of ankyrin repeats of the NOMPC-TRP ion channel is the gating spring of mechanoreceptors"
4842:
4624:
3370:
42:
474:
Shin, J. -B.; Adams, D.; Paukert, M.; Siba, M.; Sidi, S.; Levin, M.; Gillespie, P. G.; Gründer, S. (2005).
358:
Walker, R. G.; Willingham, A. T.; Zuker, C. S. (2000). "A Drosophila mechanosensory transduction channel".
77:
studies of channel segments cloned from fruit flies and zebrafish have led to the hypothesis that multiple
5145:
4992:
4709:
4581:
4487:
3853:
3498:
3401:
1393:
1380:
1367:
1347:
1334:
1299:
375:
54:
5283:
4820:
4619:
3904:
3638:
1176:
74:
1031:"C. Elegans TRP family protein TRP-4 is a pore-forming subunit of a native mechanotransduction channel"
4847:
5200:
5021:
4963:
4892:
4800:
4753:
4188:
4051:
3989:
3969:
3843:
3531:
1274:
931:
872:
674:
606:
549:
487:
427:
367:
322:
133:
94:
90:
380:
5105:
5025:
4967:
4925:
4867:
4635:
4143:
3814:
1168:
194:
141:
58:
4148:
5230:
5090:
4986:
4852:
4647:
4593:
4158:
4102:
4031:
3832:
3724:
3510:
3457:
2741:
1617:
1264:
575:
145:
4281:
5085:
4946:
4341:
4240:
4193:
4123:
5190:
5180:
4703:
4291:
4214:
4205:
4036:
3805:
3760:
3750:
3695:
3648:
3448:
1779:
1111:
1060:
1011:
959:
900:
841:
792:
743:
692:
640:
622:
567:
515:
453:
393:
340:
166:
137:
129:
117:
5205:
5115:
4881:
4719:
4183:
4128:
3789:
3473:
2548:
1529:
1101:
1091:
1050:
1042:
1001:
993:
949:
939:
890:
880:
831:
823:
782:
774:
733:
723:
682:
630:
614:
557:
505:
495:
443:
435:
385:
330:
50:
4422:
4394:
416:"A C. Elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue"
5235:
5155:
4958:
4951:
4353:
4346:
4286:
4198:
4066:
4061:
4021:
3568:
3478:
3084:
1224:
218:
106:
982:"Distinct roles of TRP channels in auditory transduction and amplification in Drosophila"
1080:"The Rise and Fall of TRP-N, an Ancient Family of Mechanogated Ion Channels, in Metazoa"
935:
876:
678:
610:
553:
491:
431:
371:
326:
4982:
4897:
4667:
4589:
4296:
3828:
3735:
3705:
3598:
3506:
2880:
1567:
1106:
1079:
1055:
1030:
1006:
981:
954:
919:
895:
860:
836:
811:
787:
762:
635:
594:
510:
475:
448:
415:
181:
125:
121:
78:
26:
861:"Drosophila TRPN( =NOMPC) Channel Localizes to the Distal End of Mechanosensory Cilia"
335:
310:
5277:
5215:
5195:
4790:
4505:
4336:
4316:
4046:
3934:
3745:
3618:
3535:
2834:
2507:
738:
711:
110:
579:
201:
TRPN has the capability of performing a variety of roles in mechanosensory systems.
85:
are involved in the gating of the channel pore. Crystallography studies of TRPY1, a
5095:
4911:
4871:
4804:
4794:
4785:
4780:
4723:
4681:
4271:
4056:
3965:
3878:
3690:
3685:
3588:
3187:
2578:
186:
73:
A structure of NOMPC was published in 2017, solved using electron cryo-microscopy.
389:
1046:
997:
885:
778:
538:"NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction"
5135:
5063:
5047:
4915:
4887:
4770:
4714:
4657:
4643:
4331:
4326:
4266:
3995:
3980:
3975:
3929:
3868:
3795:
3775:
3754:
3715:
3578:
3543:
3117:
3112:
3107:
3102:
2989:
2828:
1203:
710:
Palmer, C. P.; Zhou, X. L.; Lin, J.; Loukin, S. H.; Kung, C.; Saimi, Y. (2001).
30:
5125:
5016:
4931:
4921:
4877:
4861:
4857:
4748:
4614:
4482:
4363:
4209:
4137:
4133:
4026:
3985:
3810:
3800:
3785:
3653:
3563:
3097:
2463:
1831:
1799:
980:
Lehnert, B. P.; Baker, A. E.; Gaudry, Q; Chiang, A. S.; Wilson, R. I. (2013).
687:
662:
177:
82:
763:"The role of the TRP channel NompC in Drosophila larval and adult locomotion"
626:
595:"Electron cryo-microscopy structure of the mechanotransduction channel NOMPC"
144:. Further immunostaining studies in fruit flies have identified, with higher
5240:
5225:
5220:
5170:
5165:
4810:
4729:
4687:
4677:
3914:
3779:
3182:
3092:
944:
562:
537:
500:
190:
173:
ions, although a complete ion selectivity profile has yet to be identified.
62:
1161:
1150:
1139:
1115:
1064:
1015:
963:
904:
859:
Lee, J.; Moon, S.; Cha, Y.; Chung, Y. D. (2010). Gonzalez, Cayetano (ed.).
845:
796:
747:
728:
696:
644:
571:
519:
457:
397:
344:
209:
Genomic data from a variety of organisms show that TRPN is present in most
1128:
5175:
5160:
5129:
5119:
5109:
5099:
5080:
5068:
5037:
5032:
4996:
4907:
4760:
4699:
4671:
4661:
4639:
4321:
4306:
4230:
4168:
4153:
4113:
3919:
3894:
3847:
3838:
3765:
3731:
3675:
3670:
3632:
3628:
3602:
3592:
3582:
3572:
3558:
3516:
3411:
3195:
2543:
1522:
1517:
1512:
1507:
1439:
1434:
1096:
214:
158:
154:
618:
439:
5210:
5075:
5041:
5010:
4974:
4832:
4814:
4734:
4691:
4631:
4599:
4465:
4409:
4310:
4261:
4234:
4226:
4173:
4107:
4080:
3923:
3899:
3820:
3769:
3658:
3521:
3322:
3079:
2915:
1416:
1411:
1406:
210:
4519:
4377:
3948:
761:
Cheng, L. E.; Song, W.; Looger, L. L.; Jan, L. Y.; Jan, Y. N. (2010).
5002:
4978:
4936:
4836:
4764:
4603:
4585:
4443:
4404:
4399:
4177:
4163:
3908:
3824:
3719:
3710:
3700:
3679:
3642:
3613:
3608:
3547:
3539:
3525:
3502:
2999:
2994:
2728:
2723:
2669:
2664:
2480:
2468:
2458:
2453:
2441:
2436:
2431:
2318:
2313:
2308:
2200:
2136:
2131:
2126:
2121:
2116:
2111:
2106:
2041:
2036:
2026:
2021:
2016:
1967:
1962:
1952:
1947:
1824:
1819:
1814:
1809:
1715:
1710:
1705:
1695:
1690:
1680:
1675:
1605:
1600:
1595:
1590:
1493:
1488:
1483:
1478:
1466:
1461:
1456:
1451:
1360:
1327:
1322:
1317:
1312:
827:
170:
113:
3456:
5006:
4742:
4738:
4695:
4609:
4378:
4245:
4222:
3862:
3739:
3622:
3553:
3233:
3164:
3159:
3154:
3071:
3058:
3053:
3048:
3043:
3038:
3033:
2984:
2977:
2972:
2967:
2962:
2957:
2952:
2947:
2942:
2930:
2925:
2920:
2910:
2905:
2900:
2895:
2810:
2754:
2711:
2706:
2701:
2696:
2691:
2686:
2681:
2659:
2654:
2649:
2644:
2639:
2634:
2629:
2610:
2605:
2600:
2595:
2583:
2500:
2495:
2490:
2475:
2413:
2408:
2403:
2394:
2389:
2375:
2370:
2361:
2356:
2351:
2342:
2337:
2328:
2323:
2290:
2285:
2280:
2275:
2266:
2257:
2252:
2247:
2238:
2233:
2228:
2223:
2214:
2209:
2195:
2190:
2185:
2180:
2175:
2170:
2165:
2101:
2096:
2091:
2086:
2081:
2076:
2071:
2066:
2031:
2001:
1996:
1991:
1986:
1957:
1906:
1901:
1896:
1891:
1881:
1876:
1856:
1841:
1836:
1751:
1746:
1741:
1736:
1720:
1700:
1685:
1646:
1641:
1636:
1631:
1539:
1534:
1257:
1252:
1247:
93:
conserved across TRP family members, including TRPN, in the sixth
1029:
Kang, L.; Gao, J.; Schafer, W. R.; Xie, Z.; Xu, X. Z. S. (2010).
4941:
4775:
4520:
4466:
4427:
4118:
4081:
3949:
3313:
3308:
3303:
3293:
3288:
3283:
3273:
3268:
3263:
3258:
3253:
3248:
3243:
3228:
3223:
3218:
3213:
3208:
3203:
3142:
3137:
3132:
3127:
3122:
3028:
3016:
3011:
2937:
2890:
2854:
2849:
2844:
2839:
2566:
2384:
1942:
1279:
1269:
150:
3415:
3343:
2528:
1774:
1562:
1219:
1172:
2867:
2765:
1886:
1846:
311:"Insect mechanoreception: What a long, strange TRP it's been"
414:
Li, W.; Feng, Z.; Sternberg, P. W.; Shawn Xu, X. Z. (2006).
4826:
810:
Liang, X.; Madrid, J.; Saleh, H. S.; Howard, J. (2011).
309:
Duggan, A.; García-Añoveros, J.; Corey, D. P. (2000).
3443:
5056:
4529:
4518:
4498:
4475:
4464:
4436:
4387:
4376:
4254:
4090:
4079:
4004:
3958:
3947:
3887:
3466:
3455:
3356:
3180:
3069:
2865:
2763:
2739:
2541:
2147:
2052:
1917:
1790:
1657:
1616:
1578:
1290:
1235:
49:in TRPN. Since its discovery in fruit flies, TRPN
918:Zhang, W; Yan, Z; Jan, L. Y.; Jan, Y. N. (2013).
536:Sidi, S.; Friedrich, R. W.; Nicolson, T. (2003).
176:Studies in zebrafish larvae have also shown that
924:Proceedings of the National Academy of Sciences
716:Proceedings of the National Academy of Sciences
480:Proceedings of the National Academy of Sciences
975:
973:
229:Gene database are included whenever possible.
97:are critical to the gating mechanism as well.
3427:
1184:
124:. This hypothesis is further strengthened by
8:
656:
654:
128:studies in fruit flies that have shown TRPN
4526:
4472:
4384:
4087:
3955:
3463:
3434:
3420:
3412:
3353:
3340:
2538:
2525:
1787:
1771:
1575:
1559:
1232:
1216:
1191:
1177:
1169:
531:
529:
469:
467:
161:may also serve a mechanosensory function.
53:have been discovered and characterized in
1105:
1095:
1054:
1005:
953:
943:
894:
884:
835:
786:
737:
727:
686:
634:
561:
509:
499:
447:
379:
334:
409:
407:
301:
3614:CS gas (2-chlorobenzal malononitrile)
7:
120:, which suggests a role for TRPN in
24:transient receptor potential channel
5186:N-(p-Amylcinnamoyl)anthranilic acid
4302:N-(p-Amylcinnamoyl)anthranilic acid
4042:N-(p-Amylcinnamoyl)anthranilic acid
2557:Calcium-activated chloride channels
1627:Amiloride-sensitive cation channel
661:Howard, J.; Bechstedt, S. (2004).
41:) when it was first discovered in
14:
217:. In most animals the number of
3150:Voltage-dependent anion channel
1243:Inositol trisphosphate receptor
3172:General bacterial porin family
35:no mechanoreceptor potential C
1:
5260:Receptor/signaling modulators
3609:CR gas (dibenzoxazepine; DBO)
390:10.1126/science.287.5461.2229
336:10.1016/s0960-9822(00)00478-4
89:TRP homolog, have shown that
1084:Genome Biology and Evolution
1047:10.1016/j.neuron.2010.06.032
998:10.1016/j.neuron.2012.11.030
886:10.1371/journal.pone.0011012
779:10.1016/j.neuron.2010.07.004
16:Family of transport proteins
4888:Paracetamol (acetaminophen)
3796:Paracetamol (acetaminophen)
3666:Farnesyl thiosalicylic acid
3494:15-Deoxy-Δ-prostaglandin J2
5300:
2591:Chloride Channel Accessory
1200:Membrane transport protein
213:, but it is absent in all
5253:
3397:
3352:
3339:
2537:
2524:
1786:
1770:
1586:Epithelial sodium channel
1574:
1558:
1231:
1215:
688:10.1016/j.cub.2004.02.050
3873:Umbellularia californica
1503:Cation channels of sperm
4843:N-Arachidonoyl dopamine
4625:Andrographis paniculata
945:10.1073/pnas.1312477110
563:10.1126/science.1084370
501:10.1073/pnas.0502403102
235:Drosophila melanogaster
116:have severe difficulty
5264:Ion channel modulators
4993:Tetrahydrocannabivarin
4488:Tripterygium wilfordii
3854:Tetrahydrocannabiorcol
729:10.1073/pnas.141036198
251:Caenorhabditis elegans
221:is between 28 and 29.
4821:Lysophosphatidic acid
1579:Constitutively active
265:African clawed frog (
75:X-ray crystallography
5201:Pregnenolone sulfate
5022:Euphorbia resinifera
4964:Euphorbia resinifera
4893:Phenylacetylrinvanil
4853:N-Oleoylethanolamide
4801:Homodihydrocapsaicin
4189:Pregnenolone sulfate
4052:Pregnenolone sulfate
3859:Thiopropanal S-oxide
3844:Tetrahydrocannabinol
3532:Allyl isothiocyanate
167:Electrophysiological
134:campaniform sensilla
95:transmembrane domain
5106:Cannabigerolic acid
4868:Nordihydrocapsaicin
4829:(acidic conditions)
3346:By gating mechanism
936:2013PNAS..11013612Z
877:2010PLoSO...511012L
679:2004CBio...14.R224H
619:10.1038/nature22981
611:2017Natur.547..118J
554:2003Sci...301...96S
492:2005PNAS..10212572S
486:(35): 12572–12577.
440:10.1038/nature04538
432:2006Natur.440..684L
372:2000Sci...287.2229W
366:(5461): 2229–2234.
327:2000CBio...10.R384D
22:is a member of the
5069:Vernonia tweediana
4648:African blue basil
4620:Bisandrographolide
4206:Steviol glycosides
4159:Hydroxycitronellal
3905:Dehydroligustilide
3725:Angelica acutiloba
3639:Dehydroligustilide
2873:TRP cation channel
2771:CNG cation channel
2054:Tandem pore domain
1265:Ryanodine receptor
1162:NCBI Genbank entry
1151:NCBI Genbank entry
1140:NCBI Genbank entry
1129:NCBI Genbank entry
1097:10.1093/gbe/evv091
138:chordotonal organs
5271:
5270:
5249:
5248:
5181:Meclofenamic acid
4987:melegueta peppers
4858:Nonivamide (PAVA)
4594:melegueta peppers
4514:
4513:
4460:
4459:
4372:
4371:
4292:Meclofenamic acid
4215:Stevia rebaudiana
4075:
4074:
4037:Meclofenamic acid
3943:
3942:
3833:melegueta peppers
3806:Phenacyl chloride
3761:N-Methylmaleimide
3751:Methyl salicylate
3696:Hydrogen peroxide
3649:Diallyl disulfide
3511:melegueta peppers
3409:
3408:
3393:
3392:
3389:
3388:
3381:Stretch-activated
3358:Ion channel class
3335:
3334:
3331:
3330:
2520:
2519:
2516:
2515:
1792:Calcium-activated
1780:Potassium channel
1766:
1765:
1762:
1761:
1554:
1553:
1550:
1549:
722:(14): 7801–7805.
605:(7661): 118–122.
426:(7084): 684–687.
321:(10): R384–R387.
91:aromatic residues
5291:
5116:Cannabigerovarin
4848:N-Oleoyldopamine
4754:Euodia ruticarpa
4720:Dihydrocapsaicin
4527:
4523:
4473:
4469:
4385:
4381:
4129:Cooling Agent 10
4088:
4084:
3956:
3952:
3474:4-Hydroxynonenal
3464:
3460:
3445:
3436:
3429:
3422:
3413:
3354:
3341:
2549:Chloride channel
2539:
2526:
1919:Inward-rectifier
1788:
1772:
1576:
1560:
1530:Two-pore channel
1233:
1217:
1193:
1186:
1179:
1170:
1164:
1159:
1153:
1148:
1142:
1137:
1131:
1126:
1120:
1119:
1109:
1099:
1090:(6): 1713–1727.
1075:
1069:
1068:
1058:
1026:
1020:
1019:
1009:
977:
968:
967:
957:
947:
915:
909:
908:
898:
888:
856:
850:
849:
839:
828:10.1002/cm.20493
807:
801:
800:
790:
758:
752:
751:
741:
731:
707:
701:
700:
690:
673:(6): R224–R226.
658:
649:
648:
638:
590:
584:
583:
565:
533:
524:
523:
513:
503:
471:
462:
461:
451:
411:
402:
401:
383:
355:
349:
348:
338:
306:
142:Johnston's organ
132:in the cilia of
5299:
5298:
5294:
5293:
5292:
5290:
5289:
5288:
5274:
5273:
5272:
5267:
5245:
5236:Tolfenamic acid
5156:Flufenamic acid
5052:
4959:Resiniferatoxin
4952:Ruta graveolens
4715:Diacyl glycerol
4510:
4494:
4456:
4452:
4432:
4418:
4368:
4354:Tolfenamic acid
4347:Ruta graveolens
4287:Flufenamic acid
4250:
4199:Ruta graveolens
4110:(intracellular)
4071:
4067:Tolfenamic acid
4022:Flufenamic acid
4000:
3976:Diacyl glycerol
3939:
3883:
3569:Cannabichromene
3479:4-Oxo-2-nonenal
3451:
3440:
3410:
3405:
3385:
3348:
3327:
3176:
3075:
3065:
2861:
2759:
2735:
2533:
2512:
2426:
2303:
2160:
2143:
2048:
2012:
1982:
1938:
1930:
1913:
1867:
1782:
1758:
1731:
1670:
1653:
1612:
1570:
1546:
1429:
1401:
1388:
1375:
1355:
1342:
1307:
1286:
1227:
1225:Calcium channel
1211:
1197:
1167:
1160:
1156:
1149:
1145:
1138:
1134:
1127:
1123:
1077:
1076:
1072:
1028:
1027:
1023:
979:
978:
971:
930:(33): 13612–7.
917:
916:
912:
858:
857:
853:
809:
808:
804:
760:
759:
755:
709:
708:
704:
667:Current Biology
660:
659:
652:
592:
591:
587:
548:(5629): 96–99.
535:
534:
527:
473:
472:
465:
413:
412:
405:
381:10.1.1.646.2497
357:
356:
352:
315:Current Biology
308:
307:
303:
299:
287:
271:
255:
249:Nematode worm (
239:
219:ankyrin repeats
207:
107:mechanoreceptor
103:
79:ankyrin repeats
71:
17:
12:
11:
5:
5297:
5295:
5287:
5286:
5276:
5275:
5269:
5268:
5254:
5251:
5250:
5247:
5246:
5244:
5243:
5238:
5233:
5228:
5223:
5218:
5213:
5208:
5203:
5198:
5193:
5188:
5183:
5178:
5173:
5168:
5163:
5158:
5153:
5148:
5143:
5138:
5133:
5123:
5113:
5103:
5093:
5088:
5083:
5078:
5073:
5060:
5058:
5054:
5053:
5051:
5050:
5045:
5035:
5030:
5014:
5000:
4990:
4972:
4956:
4944:
4939:
4934:
4929:
4926:Dorrigo pepper
4919:
4905:
4898:Phorbol esters
4895:
4890:
4885:
4875:
4865:
4855:
4850:
4845:
4840:
4830:
4823:
4818:
4808:
4798:
4788:
4783:
4778:
4773:
4768:
4758:
4746:
4732:
4727:
4717:
4712:
4707:
4685:
4675:
4668:Cannabidivarin
4665:
4655:
4636:camphor laurel
4629:
4617:
4612:
4607:
4597:
4579:
4574:
4569:
4564:
4559:
4554:
4549:
4544:
4539:
4533:
4531:
4524:
4516:
4515:
4512:
4511:
4509:
4508:
4502:
4500:
4496:
4495:
4493:
4492:
4479:
4477:
4470:
4462:
4461:
4458:
4457:
4455:
4454:
4450:
4446:
4440:
4438:
4434:
4433:
4431:
4430:
4425:
4420:
4416:
4412:
4407:
4402:
4397:
4391:
4389:
4382:
4374:
4373:
4370:
4369:
4367:
4366:
4361:
4356:
4351:
4339:
4334:
4329:
4324:
4319:
4314:
4304:
4299:
4297:Mefenamic acid
4294:
4289:
4284:
4279:
4274:
4269:
4264:
4258:
4256:
4252:
4251:
4249:
4248:
4243:
4238:
4219:
4203:
4191:
4186:
4181:
4171:
4166:
4161:
4156:
4151:
4146:
4141:
4131:
4126:
4121:
4116:
4111:
4105:
4100:
4094:
4092:
4085:
4077:
4076:
4073:
4072:
4070:
4069:
4064:
4059:
4054:
4049:
4044:
4039:
4034:
4029:
4024:
4019:
4014:
4008:
4006:
4002:
4001:
3999:
3998:
3993:
3990:St John's wort
3983:
3978:
3973:
3970:St John's wort
3962:
3960:
3953:
3945:
3944:
3941:
3940:
3938:
3937:
3932:
3927:
3917:
3912:
3902:
3897:
3891:
3889:
3885:
3884:
3882:
3881:
3876:
3866:
3856:
3851:
3841:
3836:
3818:
3815:Dorrigo pepper
3808:
3803:
3798:
3793:
3783:
3773:
3763:
3758:
3748:
3743:
3736:Sichuan pepper
3729:
3713:
3708:
3706:Isothiocyanate
3703:
3698:
3693:
3688:
3683:
3673:
3668:
3663:
3651:
3646:
3636:
3626:
3616:
3611:
3606:
3599:Cinnamaldehyde
3596:
3586:
3576:
3566:
3561:
3556:
3551:
3529:
3519:
3514:
3496:
3491:
3486:
3481:
3476:
3470:
3468:
3461:
3453:
3452:
3441:
3439:
3438:
3431:
3424:
3416:
3407:
3406:
3398:
3395:
3394:
3391:
3390:
3387:
3386:
3384:
3383:
3378:
3373:
3368:
3362:
3360:
3350:
3349:
3344:
3337:
3336:
3333:
3332:
3329:
3328:
3326:
3325:
3320:
3319:
3318:
3317:
3316:
3311:
3306:
3298:
3297:
3296:
3291:
3286:
3278:
3277:
3276:
3271:
3266:
3261:
3256:
3251:
3246:
3238:
3237:
3236:
3231:
3226:
3221:
3216:
3211:
3206:
3192:
3190:
3178:
3177:
3175:
3174:
3169:
3168:
3167:
3162:
3157:
3147:
3146:
3145:
3140:
3135:
3130:
3125:
3120:
3115:
3110:
3105:
3100:
3089:
3087:
3073:
3067:
3066:
3064:
3063:
3062:
3061:
3056:
3051:
3046:
3041:
3036:
3026:
3025:
3024:
3019:
3009:
3004:
3003:
3002:
2997:
2992:
2982:
2981:
2980:
2975:
2970:
2965:
2960:
2955:
2950:
2945:
2935:
2934:
2933:
2928:
2923:
2918:
2913:
2908:
2903:
2898:
2888:
2877:
2875:
2863:
2862:
2860:
2859:
2858:
2857:
2852:
2847:
2842:
2837:
2825:
2824:
2823:
2818:
2813:
2803:
2802:
2801:
2796:
2791:
2786:
2775:
2773:
2761:
2760:
2758:
2757:
2751:
2749:
2747:Proton channel
2737:
2736:
2734:
2733:
2732:
2731:
2726:
2716:
2715:
2714:
2709:
2704:
2699:
2694:
2689:
2684:
2674:
2673:
2672:
2667:
2662:
2657:
2652:
2647:
2642:
2637:
2632:
2622:
2617:
2616:
2615:
2614:
2613:
2608:
2603:
2598:
2588:
2587:
2586:
2581:
2571:
2570:
2569:
2553:
2551:
2535:
2534:
2529:
2522:
2521:
2518:
2517:
2514:
2513:
2511:
2510:
2505:
2504:
2503:
2498:
2493:
2483:
2478:
2473:
2472:
2471:
2466:
2461:
2456:
2446:
2445:
2444:
2439:
2434:
2424:
2419:
2418:
2417:
2416:
2411:
2406:
2399:
2398:
2397:
2392:
2387:
2380:
2379:
2378:
2373:
2366:
2365:
2364:
2359:
2354:
2347:
2346:
2345:
2340:
2333:
2332:
2331:
2326:
2321:
2316:
2311:
2301:
2296:
2295:
2294:
2293:
2288:
2283:
2278:
2271:
2270:
2269:
2262:
2261:
2260:
2255:
2250:
2243:
2242:
2241:
2236:
2231:
2226:
2219:
2218:
2217:
2212:
2205:
2204:
2203:
2198:
2193:
2188:
2183:
2178:
2173:
2168:
2158:
2153:
2151:
2145:
2144:
2142:
2141:
2140:
2139:
2134:
2129:
2124:
2119:
2114:
2109:
2104:
2099:
2094:
2089:
2084:
2079:
2074:
2069:
2058:
2056:
2050:
2049:
2047:
2046:
2045:
2044:
2039:
2034:
2029:
2024:
2019:
2010:
2006:
2005:
2004:
1999:
1994:
1989:
1980:
1972:
1971:
1970:
1965:
1960:
1955:
1950:
1945:
1936:
1932:
1928:
1923:
1921:
1915:
1914:
1912:
1911:
1910:
1909:
1904:
1899:
1894:
1889:
1884:
1879:
1874:
1865:
1861:
1860:
1859:
1851:
1850:
1849:
1844:
1839:
1829:
1828:
1827:
1822:
1817:
1812:
1807:
1796:
1794:
1784:
1783:
1775:
1768:
1767:
1764:
1763:
1760:
1759:
1757:
1756:
1755:
1754:
1749:
1744:
1739:
1729:
1725:
1724:
1723:
1718:
1713:
1708:
1703:
1698:
1693:
1688:
1683:
1678:
1668:
1663:
1661:
1655:
1654:
1652:
1651:
1650:
1649:
1644:
1639:
1634:
1623:
1621:
1614:
1613:
1611:
1610:
1609:
1608:
1603:
1598:
1593:
1582:
1580:
1572:
1571:
1568:Sodium channel
1563:
1556:
1555:
1552:
1551:
1548:
1547:
1545:
1544:
1543:
1542:
1537:
1527:
1526:
1525:
1520:
1515:
1510:
1499:
1498:
1497:
1496:
1491:
1486:
1481:
1471:
1470:
1469:
1464:
1459:
1454:
1444:
1443:
1442:
1437:
1427:
1422:
1421:
1420:
1419:
1414:
1409:
1399:
1391:
1386:
1378:
1373:
1365:
1364:
1363:
1353:
1345:
1340:
1332:
1331:
1330:
1325:
1320:
1315:
1305:
1296:
1294:
1288:
1287:
1285:
1284:
1283:
1282:
1277:
1272:
1262:
1261:
1260:
1255:
1250:
1239:
1237:
1229:
1228:
1220:
1213:
1212:
1198:
1196:
1195:
1188:
1181:
1173:
1166:
1165:
1154:
1143:
1132:
1121:
1070:
1041:(3): 381–391.
1021:
969:
910:
851:
802:
773:(3): 373–380.
753:
702:
650:
585:
525:
463:
403:
350:
300:
298:
295:
294:
293:
286:
279:
278:
277:
270:
267:Xenopus laevis
263:
262:
261:
254:
247:
246:
245:
238:
231:
206:
203:
126:immunostaining
122:proprioception
102:
99:
70:
67:
15:
13:
10:
9:
6:
4:
3:
2:
5296:
5285:
5282:
5281:
5279:
5266:
5265:
5261:
5258:
5252:
5242:
5239:
5237:
5234:
5232:
5229:
5227:
5224:
5222:
5219:
5217:
5216:Ruthenium red
5214:
5212:
5209:
5207:
5204:
5202:
5199:
5197:
5196:Niflumic acid
5194:
5192:
5189:
5187:
5184:
5182:
5179:
5177:
5174:
5172:
5169:
5167:
5164:
5162:
5159:
5157:
5154:
5152:
5149:
5147:
5144:
5142:
5139:
5137:
5134:
5131:
5127:
5124:
5121:
5117:
5114:
5111:
5107:
5104:
5101:
5097:
5094:
5092:
5089:
5087:
5084:
5082:
5079:
5077:
5074:
5071:
5070:
5065:
5064:α-Spinasterol
5062:
5061:
5059:
5055:
5049:
5046:
5043:
5039:
5036:
5034:
5031:
5028:
5027:
5023:
5018:
5015:
5012:
5008:
5004:
5001:
4998:
4994:
4991:
4988:
4984:
4980:
4976:
4973:
4970:
4969:
4965:
4960:
4957:
4954:
4953:
4948:
4945:
4943:
4940:
4938:
4935:
4933:
4930:
4927:
4923:
4920:
4917:
4913:
4909:
4906:
4903:
4899:
4896:
4894:
4891:
4889:
4886:
4883:
4879:
4876:
4873:
4869:
4866:
4863:
4859:
4856:
4854:
4851:
4849:
4846:
4844:
4841:
4838:
4834:
4831:
4828:
4824:
4822:
4819:
4816:
4812:
4809:
4806:
4802:
4799:
4796:
4792:
4791:Homocapsaicin
4789:
4787:
4784:
4782:
4779:
4777:
4774:
4772:
4769:
4766:
4762:
4759:
4756:
4755:
4750:
4747:
4744:
4740:
4736:
4733:
4731:
4728:
4725:
4721:
4718:
4716:
4713:
4711:
4708:
4705:
4704:wild bergamot
4701:
4697:
4693:
4689:
4686:
4683:
4679:
4676:
4673:
4669:
4666:
4663:
4659:
4656:
4653:
4652:camphor basil
4649:
4645:
4641:
4637:
4633:
4630:
4627:
4626:
4621:
4618:
4616:
4613:
4611:
4608:
4605:
4601:
4598:
4595:
4591:
4587:
4583:
4580:
4578:
4575:
4573:
4570:
4568:
4565:
4563:
4560:
4558:
4555:
4553:
4550:
4548:
4545:
4543:
4540:
4538:
4535:
4534:
4532:
4528:
4525:
4522:
4517:
4507:
4506:Ruthenium red
4504:
4503:
4501:
4497:
4490:
4489:
4484:
4481:
4480:
4478:
4474:
4471:
4468:
4463:
4453:
4447:
4445:
4442:
4441:
4439:
4435:
4429:
4426:
4424:
4421:
4419:
4413:
4411:
4408:
4406:
4403:
4401:
4398:
4396:
4393:
4392:
4390:
4386:
4383:
4380:
4375:
4365:
4362:
4360:
4357:
4355:
4352:
4349:
4348:
4343:
4340:
4338:
4337:Ruthenium red
4335:
4333:
4330:
4328:
4325:
4323:
4320:
4318:
4317:Niflumic acid
4315:
4312:
4308:
4305:
4303:
4300:
4298:
4295:
4293:
4290:
4288:
4285:
4283:
4280:
4278:
4275:
4273:
4270:
4268:
4265:
4263:
4260:
4259:
4257:
4253:
4247:
4244:
4242:
4239:
4237:; indirectly)
4236:
4232:
4228:
4224:
4220:
4217:
4216:
4211:
4207:
4204:
4201:
4200:
4195:
4192:
4190:
4187:
4185:
4182:
4179:
4175:
4172:
4170:
4167:
4165:
4162:
4160:
4157:
4155:
4152:
4150:
4147:
4145:
4144:Frescolat MGA
4142:
4139:
4135:
4132:
4130:
4127:
4125:
4122:
4120:
4117:
4115:
4112:
4109:
4106:
4104:
4101:
4099:
4096:
4095:
4093:
4089:
4086:
4083:
4078:
4068:
4065:
4063:
4060:
4058:
4055:
4053:
4050:
4048:
4047:Niflumic acid
4045:
4043:
4040:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4009:
4007:
4003:
3997:
3994:
3991:
3987:
3984:
3982:
3979:
3977:
3974:
3971:
3967:
3964:
3963:
3961:
3957:
3954:
3951:
3946:
3936:
3935:Ruthenium red
3933:
3931:
3928:
3925:
3921:
3918:
3916:
3913:
3910:
3906:
3903:
3901:
3898:
3896:
3893:
3892:
3890:
3886:
3880:
3877:
3874:
3870:
3867:
3864:
3860:
3857:
3855:
3852:
3849:
3845:
3842:
3840:
3837:
3834:
3830:
3826:
3822:
3819:
3816:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3791:
3787:
3784:
3781:
3777:
3774:
3771:
3767:
3764:
3762:
3759:
3756:
3752:
3749:
3747:
3746:Methylglyoxal
3744:
3741:
3737:
3733:
3730:
3727:
3726:
3721:
3717:
3714:
3712:
3709:
3707:
3704:
3702:
3699:
3697:
3694:
3692:
3689:
3687:
3684:
3681:
3677:
3674:
3672:
3669:
3667:
3664:
3661:
3660:
3655:
3652:
3650:
3647:
3644:
3640:
3637:
3634:
3630:
3627:
3624:
3620:
3619:Cuminaldehyde
3617:
3615:
3612:
3610:
3607:
3604:
3600:
3597:
3594:
3590:
3587:
3584:
3580:
3577:
3574:
3570:
3567:
3565:
3562:
3560:
3557:
3555:
3552:
3549:
3545:
3541:
3537:
3533:
3530:
3527:
3523:
3520:
3518:
3515:
3512:
3508:
3504:
3500:
3497:
3495:
3492:
3490:
3487:
3485:
3482:
3480:
3477:
3475:
3472:
3471:
3469:
3465:
3462:
3459:
3454:
3450:
3447:
3437:
3432:
3430:
3425:
3423:
3418:
3417:
3414:
3404:
3403:
3396:
3382:
3379:
3377:
3376:Voltage-gated
3374:
3372:
3369:
3367:
3364:
3363:
3361:
3359:
3355:
3351:
3347:
3342:
3338:
3324:
3321:
3315:
3312:
3310:
3307:
3305:
3302:
3301:
3299:
3295:
3292:
3290:
3287:
3285:
3282:
3281:
3279:
3275:
3272:
3270:
3267:
3265:
3262:
3260:
3257:
3255:
3252:
3250:
3247:
3245:
3242:
3241:
3239:
3235:
3232:
3230:
3227:
3225:
3222:
3220:
3217:
3215:
3212:
3210:
3207:
3205:
3202:
3201:
3199:
3198:
3197:
3194:
3193:
3191:
3189:
3186:
3184:
3179:
3173:
3170:
3166:
3163:
3161:
3158:
3156:
3153:
3152:
3151:
3148:
3144:
3141:
3139:
3136:
3134:
3131:
3129:
3126:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3099:
3096:
3095:
3094:
3091:
3090:
3088:
3086:
3083:
3081:
3077:
3068:
3060:
3057:
3055:
3052:
3050:
3047:
3045:
3042:
3040:
3037:
3035:
3032:
3031:
3030:
3027:
3023:
3020:
3018:
3015:
3014:
3013:
3010:
3008:
3005:
3001:
2998:
2996:
2993:
2991:
2988:
2987:
2986:
2983:
2979:
2976:
2974:
2971:
2969:
2966:
2964:
2961:
2959:
2956:
2954:
2951:
2949:
2946:
2944:
2941:
2940:
2939:
2936:
2932:
2929:
2927:
2924:
2922:
2919:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2899:
2897:
2894:
2893:
2892:
2889:
2886:
2882:
2879:
2878:
2876:
2874:
2871:
2869:
2864:
2856:
2853:
2851:
2848:
2846:
2843:
2841:
2838:
2836:
2833:
2832:
2831:
2830:
2826:
2822:
2819:
2817:
2814:
2812:
2809:
2808:
2807:
2804:
2800:
2797:
2795:
2792:
2790:
2787:
2785:
2782:
2781:
2780:
2777:
2776:
2774:
2772:
2769:
2767:
2762:
2756:
2753:
2752:
2750:
2748:
2745:
2743:
2738:
2730:
2727:
2725:
2722:
2721:
2720:
2717:
2713:
2710:
2708:
2705:
2703:
2700:
2698:
2695:
2693:
2690:
2688:
2685:
2683:
2680:
2679:
2678:
2675:
2671:
2668:
2666:
2663:
2661:
2658:
2656:
2653:
2651:
2648:
2646:
2643:
2641:
2638:
2636:
2633:
2631:
2628:
2627:
2626:
2623:
2621:
2618:
2612:
2609:
2607:
2604:
2602:
2599:
2597:
2594:
2593:
2592:
2589:
2585:
2582:
2580:
2577:
2576:
2575:
2572:
2568:
2565:
2564:
2563:
2560:
2559:
2558:
2555:
2554:
2552:
2550:
2547:
2545:
2540:
2536:
2532:
2531:Miscellaneous
2527:
2523:
2509:
2508:Shaker (gene)
2506:
2502:
2499:
2497:
2494:
2492:
2489:
2488:
2487:
2484:
2482:
2481:minK/ISK-like
2479:
2477:
2474:
2470:
2467:
2465:
2462:
2460:
2457:
2455:
2452:
2451:
2450:
2447:
2443:
2440:
2438:
2435:
2433:
2430:
2429:
2428:
2421:
2420:
2415:
2412:
2410:
2407:
2405:
2402:
2401:
2400:
2396:
2393:
2391:
2388:
2386:
2383:
2382:
2381:
2377:
2374:
2372:
2369:
2368:
2367:
2363:
2360:
2358:
2355:
2353:
2350:
2349:
2348:
2344:
2341:
2339:
2336:
2335:
2334:
2330:
2327:
2325:
2322:
2320:
2317:
2315:
2312:
2310:
2307:
2306:
2305:
2298:
2297:
2292:
2289:
2287:
2284:
2282:
2279:
2277:
2274:
2273:
2272:
2268:
2265:
2264:
2263:
2259:
2256:
2254:
2251:
2249:
2246:
2245:
2244:
2240:
2237:
2235:
2232:
2230:
2227:
2225:
2222:
2221:
2220:
2216:
2213:
2211:
2208:
2207:
2206:
2202:
2199:
2197:
2194:
2192:
2189:
2187:
2184:
2182:
2179:
2177:
2174:
2172:
2169:
2167:
2164:
2163:
2162:
2155:
2154:
2152:
2150:
2149:Voltage-gated
2146:
2138:
2135:
2133:
2130:
2128:
2125:
2123:
2120:
2118:
2115:
2113:
2110:
2108:
2105:
2103:
2100:
2098:
2095:
2093:
2090:
2088:
2085:
2083:
2080:
2078:
2075:
2073:
2070:
2068:
2065:
2064:
2063:
2060:
2059:
2057:
2055:
2051:
2043:
2040:
2038:
2035:
2033:
2030:
2028:
2025:
2023:
2020:
2018:
2015:
2014:
2013:
2007:
2003:
2000:
1998:
1995:
1993:
1990:
1988:
1985:
1984:
1983:
1976:
1973:
1969:
1966:
1964:
1961:
1959:
1956:
1954:
1951:
1949:
1946:
1944:
1941:
1940:
1939:
1933:
1931:
1925:
1924:
1922:
1920:
1916:
1908:
1905:
1903:
1900:
1898:
1895:
1893:
1890:
1888:
1885:
1883:
1880:
1878:
1875:
1873:
1870:
1869:
1868:
1862:
1858:
1855:
1854:
1852:
1848:
1845:
1843:
1840:
1838:
1835:
1834:
1833:
1830:
1826:
1823:
1821:
1818:
1816:
1813:
1811:
1808:
1806:
1803:
1802:
1801:
1798:
1797:
1795:
1793:
1789:
1785:
1781:
1778:
1773:
1769:
1753:
1750:
1748:
1745:
1743:
1740:
1738:
1735:
1734:
1733:
1726:
1722:
1719:
1717:
1714:
1712:
1709:
1707:
1704:
1702:
1699:
1697:
1694:
1692:
1689:
1687:
1684:
1682:
1679:
1677:
1674:
1673:
1672:
1665:
1664:
1662:
1660:
1659:Voltage-gated
1656:
1648:
1645:
1643:
1640:
1638:
1635:
1633:
1630:
1629:
1628:
1625:
1624:
1622:
1619:
1615:
1607:
1604:
1602:
1599:
1597:
1594:
1592:
1589:
1588:
1587:
1584:
1583:
1581:
1577:
1573:
1569:
1566:
1561:
1557:
1541:
1538:
1536:
1533:
1532:
1531:
1528:
1524:
1521:
1519:
1516:
1514:
1511:
1509:
1506:
1505:
1504:
1501:
1500:
1495:
1492:
1490:
1487:
1485:
1482:
1480:
1477:
1476:
1475:
1472:
1468:
1465:
1463:
1460:
1458:
1455:
1453:
1450:
1449:
1448:
1445:
1441:
1438:
1436:
1433:
1432:
1431:
1424:
1423:
1418:
1415:
1413:
1410:
1408:
1405:
1404:
1403:
1395:
1392:
1390:
1382:
1379:
1377:
1369:
1366:
1362:
1359:
1358:
1357:
1349:
1346:
1344:
1336:
1333:
1329:
1326:
1324:
1321:
1319:
1316:
1314:
1311:
1310:
1309:
1301:
1298:
1297:
1295:
1293:
1292:Voltage-gated
1289:
1281:
1278:
1276:
1273:
1271:
1268:
1267:
1266:
1263:
1259:
1256:
1254:
1251:
1249:
1246:
1245:
1244:
1241:
1240:
1238:
1234:
1230:
1226:
1223:
1218:
1214:
1209:
1205:
1201:
1194:
1189:
1187:
1182:
1180:
1175:
1174:
1171:
1163:
1158:
1155:
1152:
1147:
1144:
1141:
1136:
1133:
1130:
1125:
1122:
1117:
1113:
1108:
1103:
1098:
1093:
1089:
1085:
1081:
1074:
1071:
1066:
1062:
1057:
1052:
1048:
1044:
1040:
1036:
1032:
1025:
1022:
1017:
1013:
1008:
1003:
999:
995:
992:(1): 115–28.
991:
987:
983:
976:
974:
970:
965:
961:
956:
951:
946:
941:
937:
933:
929:
925:
921:
914:
911:
906:
902:
897:
892:
887:
882:
878:
874:
871:(6): e11012.
870:
866:
862:
855:
852:
847:
843:
838:
833:
829:
825:
821:
817:
813:
806:
803:
798:
794:
789:
784:
780:
776:
772:
768:
764:
757:
754:
749:
745:
740:
735:
730:
725:
721:
717:
713:
706:
703:
698:
694:
689:
684:
680:
676:
672:
668:
664:
657:
655:
651:
646:
642:
637:
632:
628:
624:
620:
616:
612:
608:
604:
600:
596:
589:
586:
581:
577:
573:
569:
564:
559:
555:
551:
547:
543:
539:
532:
530:
526:
521:
517:
512:
507:
502:
497:
493:
489:
485:
481:
477:
470:
468:
464:
459:
455:
450:
445:
441:
437:
433:
429:
425:
421:
417:
410:
408:
404:
399:
395:
391:
387:
382:
377:
373:
369:
365:
361:
354:
351:
346:
342:
337:
332:
328:
324:
320:
316:
312:
305:
302:
296:
292:
289:
288:
284:
280:
276:
273:
272:
268:
264:
260:
257:
256:
252:
248:
244:
241:
240:
236:
232:
230:
228:
222:
220:
216:
212:
204:
202:
199:
196:
193:and ciliated
192:
188:
183:
179:
174:
172:
168:
162:
160:
156:
152:
147:
143:
139:
135:
131:
127:
123:
119:
115:
112:
108:
100:
98:
96:
92:
88:
84:
80:
76:
68:
66:
64:
60:
56:
52:
48:
44:
40:
36:
32:
28:
25:
21:
5284:Ion channels
5256:
5255:
5096:Cannabigerol
5067:
5020:
4962:
4950:
4912:black pepper
4872:chili pepper
4805:chili pepper
4795:chili pepper
4786:Hepoxilin B3
4781:Hepoxilin A3
4752:
4724:chili pepper
4682:chili pepper
4623:
4486:
4345:
4272:Clotrimazole
4213:
4197:
4149:Frescolat ML
4057:Progesterone
3966:Adhyperforin
3879:WIN 55,212-2
3872:
3723:
3691:Hepoxilin B3
3686:Hepoxilin A3
3657:
3589:Cannabigerol
3399:
3366:Ligand-gated
3357:
3345:
3188:Gap junction
3181:
3070:
3006:
2866:
2827:
2805:
2778:
2764:
2740:
2718:
2676:
2624:
2590:
2573:
2561:
2542:
2530:
2485:
2448:
2422:
2299:
2156:
2061:
2008:
1978:
1934:
1863:
1776:
1727:
1666:
1564:
1473:
1446:
1425:
1397:
1384:
1371:
1351:
1338:
1303:
1236:Ligand-gated
1221:
1204:ion channels
1157:
1146:
1135:
1124:
1087:
1083:
1073:
1038:
1034:
1024:
989:
985:
927:
923:
913:
868:
864:
854:
819:
816:Cytoskeleton
815:
805:
770:
766:
756:
719:
715:
705:
670:
666:
602:
598:
588:
545:
541:
483:
479:
423:
419:
363:
359:
353:
318:
314:
304:
290:
282:
274:
266:
258:
250:
242:
234:
223:
208:
200:
187:lateral line
175:
163:
130:localization
104:
72:
46:
45:, hence the
38:
34:
31:ion channels
19:
18:
5231:Tivanisiran
5136:Capsazepine
5048:Zucapsaicin
4916:long pepper
4882:Pacific yew
4771:GSK1016790A
4658:Cannabidiol
4644:camphorweed
4332:RQ-00203078
4327:PF-05105679
4267:Capsazepine
4032:GSK2293017A
3996:Substance P
3981:GSK1702934A
3930:PF-04745637
3869:Umbellulone
3790:Pacific yew
3776:Oleocanthal
3755:wintergreen
3716:Ligustilide
3579:Cannabidiol
3544:horseradish
3371:Light-gated
1853:IK channel
283:Danio rerio
281:Zebrafish (
233:Fruit fly (
43:fruit flies
5126:Cannabinol
5026:pooissonii
5017:Tinyatoxin
4968:pooissonii
4932:Probenecid
4922:Polygodial
4878:Paclitaxel
4862:PAVA spray
4749:Evodiamine
4700:pepperwort
4615:Anandamide
4582:α-Sanshool
4530:Activators
4483:Triptolide
4476:Activators
4388:Activators
4364:TRPM4-IN-5
4282:Elismetrep
4210:stevioside
4138:eucalyptus
4134:Eucalyptol
4098:ADP-ribose
4091:Activators
4027:GSK417651A
3986:Hyperforin
3959:Activators
3839:Tear gases
3811:Polygodial
3801:PF-4840154
3786:Paclitaxel
3654:Dicentrine
3564:Bradykinin
3499:α-Sanshool
3467:Activators
3449:modulators
2574:Bestrophin
1832:SK channel
1800:BK channel
1474:γ-subunits
1447:β-subunits
1430:δ-subunits
822:(1): 1–7.
297:References
191:hair cells
180:-mediated
178:morpholino
146:resolution
83:N-terminus
81:at TRPN's
5257:See also:
5241:TRPV3-74a
5226:SB-705498
5221:SB-366791
5171:Lanthanum
5166:HC-067047
5086:Asivatrep
4947:Rutamarin
4811:Incensole
4761:Gingerols
4730:Estradiol
4706:, others)
4688:Carvacrol
4678:Capsaicin
4572:13-oxoODE
4562:12S-HpETE
4542:5',6'-EET
4342:Rutamarin
4241:Thio-BCTC
4194:Rutamarin
4124:Coolact P
3915:HC-030031
3780:olive oil
3676:Gingerols
3489:12S-HpETE
3402:disorders
3400:see also
3183:Cytoplasm
3093:Aquaporin
2562:Anoctamin
2385:11.1/hERG
627:1476-4687
376:CiteSeerX
195:epidermal
182:knockdown
153:channels
69:Structure
63:zebrafish
5278:Category
5191:NGD-8243
5176:Mavatrep
5161:GRC-6211
5130:cannabis
5120:cannabis
5110:cannabis
5100:cannabis
5081:AMG-9810
5057:Blockers
5038:Vanillin
5033:Tramadol
4997:cannabis
4975:Shogaols
4908:Piperine
4672:cannabis
4662:cannabis
4640:rosemary
4557:12S-HETE
4552:9-oxoODE
4499:Blockers
4449:PI(4,5)P
4437:Blockers
4415:PI(3,5)P
4322:Ononetin
4307:Nicotine
4255:Blockers
4231:fructose
4223:tastants
4169:Linalool
4154:Geraniol
4114:CIM-0216
4005:Blockers
3920:Nicotine
3895:A-967079
3888:Blockers
3848:cannabis
3821:Shogaols
3766:Nicotine
3732:Linalool
3671:Formalin
3633:turmeric
3629:Curcumin
3603:cinnamon
3593:cannabis
3583:cannabis
3573:cannabis
3559:ASP-7663
3517:Acrolein
3196:Connexin
2476:minK/ISK
1116:26100409
1065:20696377
1016:23312520
964:23898199
905:20543979
865:PLOS ONE
846:21069788
797:20696376
748:11427713
697:15043829
645:28658211
580:23882972
572:12805553
520:16116094
458:16572173
398:10744543
345:10837217
215:amniotes
159:inactive
155:nanchung
101:Function
51:homologs
5211:RN-9893
5206:RN-1734
5076:AMG-517
5042:vanilla
5011:oregano
4983:Sichuan
4961:(RTX) (
4937:Protons
4900:(e.g.,
4833:Menthol
4815:incense
4735:Eugenol
4692:oregano
4632:Camphor
4600:Allicin
4590:Sichuan
4577:20-HETE
4567:13-HODE
4410:ML2-SA1
4311:tobacco
4262:AMG-333
4235:sucrose
4227:glucose
4225:(e.g.,
4208:(e.g.,
4174:Menthol
4108:Calcium
3924:tobacco
3900:AM-0902
3829:Sichuan
3770:tobacco
3659:Lindera
3536:mustard
3522:Allicin
3507:Sichuan
3484:4,5-EET
3446:channel
3323:Innexin
3080:solutes
1107:4494053
1056:2928144
1007:3811118
955:3746866
932:Bibcode
896:2882365
873:Bibcode
837:3048163
788:2933178
675:Bibcode
636:5669069
607:Bibcode
550:Bibcode
542:Science
511:1194908
488:Bibcode
449:2865900
428:Bibcode
368:Bibcode
360:Science
323:Bibcode
211:animals
114:mutants
5151:DHEA-S
5003:Thymol
4979:ginger
4902:4α-PDD
4765:ginger
4604:garlic
4586:ginger
4547:9-HODE
4444:ML-SI3
4405:ML-SA1
4400:MK6-83
4221:Sweet
4184:PMD 38
4164:Icilin
4017:DHEA-S
3909:celery
3825:ginger
3720:celery
3711:JT-010
3701:Icilin
3680:ginger
3643:celery
3548:wasabi
3540:radish
3526:garlic
3503:ginger
1620:-gated
1618:Proton
1394:T-type
1381:R-type
1368:Q-type
1348:P-type
1335:N-type
1300:L-type
1114:
1104:
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1035:Neuron
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420:Nature
396:
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171:sodium
118:moving
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27:family
5141:DCDPC
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4743:clove
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4696:thyme
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4537:2-APB
4423:SF-22
4395:EVP21
4379:TRPML
4277:DCDPC
4246:WS-12
4012:DCDPC
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3740:thyme
3662:spp.)
3623:cumin
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3085:Porin
2985:TRPML
2755:HVCN1
2449:KCNIP
2304:α7-12
1208:TC 1A
739:35422
576:S2CID
291:trpn1
275:nompc
259:trp-4
243:nompC
205:Genes
105:As a
87:yeast
59:frogs
55:worms
39:nompC
5146:DHEA
5091:BCTC
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1975:GIRK
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1012:PMID
960:PMID
901:PMID
842:PMID
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744:PMID
693:PMID
641:PMID
623:ISSN
568:PMID
516:PMID
454:PMID
394:PMID
341:PMID
227:NCBI
157:and
151:TRPV
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111:null
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2324:7.4
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2017:4.1
2002:3.4
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1992:3.2
1987:3.1
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1981:ir
1937:ir
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